Structure and organization of the hepatitis C virus genome isolated from human carriers.

abstract：:It has been previously shown that rotavirus maturation and stability of the outer capsid are calcium-dependent processes. More recently, it has been hypothesized that penetration of the cell membrane is also affected by conformational changes of the capsid induced by Ca2+. In this study, we determined quantitatively t...

journal_title：Journal of virology

authors： Ruiz MC,Charpilienne A,Liprandi F,Gajardo R,Michelangeli F,Cohen J

更新日期：1996-08-01 00:00:00

abstract：:In most prion diseases, infectivity accumulates in lymphoreticular organs early after infection. Defects in hematopoietic compartments, such as impaired B-cell maturation, or in stromal compartments, such as abrogation of follicular dendritic cells, can delay or prevent lymphoreticular prion colonization. However, the...

journal_title：Journal of virology

authors： Kaeser PS,Klein MA,Schwarz P,Aguzzi A

更新日期：2001-08-01 00:00:00

abstract：:Two major outer envelope glycoproteins of Epstein-Barr virus, gp350 and gp220, are known to be encoded by 3.2- and 2.5-kilobase RNAs which map to the same DNA fragment (M. Hummel, D. Thorley-Lawson, and E. Kieff, J. Virol. 49:413-417). These RNAs have the same 5' and 3' ends. The larger RNA is encoded by a 2,777-base ...

journal_title：Journal of virology

authors： Beisel C,Tanner J,Matsuo T,Thorley-Lawson D,Kezdy F,Kieff E

更新日期：1985-06-01 00:00:00

abstract：:Eight nonoverlapping regions of the hemagglutinin (HA) molecule of influenza virus A/PR/8/34 (PR8), which serve as recognition sites for class II-restricted T cells (TH) from BALB/c mice, have been identified in the form of 10- to 15-amino-acid-long synthetic peptides. These TH determinants are located between residue...

journal_title：Journal of virology

authors： Gerhard W,Haberman AM,Scherle PA,Taylor AH,Palladino G,Caton AJ

更新日期：1991-01-01 00:00:00

abstract：:Infection of neonatal mice with lymphocytic choriomeningitis virus (LCMV) strain Armstrong (ARM) results in a lifelong persistent infection. Viral variants (cytotoxic T lymphocyte [CTL] negative, persistence positive [CTL- P+]) can be isolated from the lymphoid tissues of such mice. Adult mice inoculated with these CT...

journal_title：Journal of virology

authors： Evans CF,Borrow P,de la Torre JC,Oldstone MB

更新日期：1994-11-01 00:00:00

abstract：:Replication of human papillomavirus type 11 (HPV-11) DNA requires the full-length viral E1 and E2 proteins (C.-M. Chiang, M. Ustav, A. Stenlund, T. F. Ho, T. R. Broker, and L. T. Chow, Proc. Natl. Acad. Sci. USA 89:5799-5803, 1992). Using transient transfection of subgenomic HPV DNA into hamster CHO and human 293 cell...

journal_title：Journal of virology

authors： Chiang CM,Dong G,Broker TR,Chow LT

更新日期：1992-09-01 00:00:00

abstract：:ETnII elements are mobile members of the repetitive early transposon family of mouse long terminal repeat (LTR) retroelements and have caused a number of mutations by inserting into genes. ETnII sequences lack retroviral genes, but the recent discovery of related MusD retroviral elements with regions similar to gag, p...

journal_title：Journal of virology

authors： Baust C,Gagnier L,Baillie GJ,Harris MJ,Juriloff DM,Mager DL

更新日期：2003-11-01 00:00:00

abstract：:Infection of mouse L-cell spinner cultures by vesicular stomatitis virus (VSV) effected the selective translation of viral mRNA by 4h after viral adsorption. Cell-free systems prepared from mock- and VSV-infected cells reflected this phenomenon; protein synthesis was reduced in the virus-infected cell lysate by approx...

journal_title：Journal of virology

authors： Centrella M,Lucas-Lenard J

更新日期：1982-03-01 00:00:00

abstract：:We previously showed that the cellular proteins ZEB1 and ZEB2/SIP1 both play key roles in regulating the latent-lytic switch of Epstein-Barr Virus (EBV) by repressing BZLF1 gene expression. We investigated here the effects of cellular microRNA (miRNA) 200 (miR200) family members on the EBV infection status of cells. W...

journal_title：Journal of virology

authors： Ellis-Connell AL,Iempridee T,Xu I,Mertz JE

更新日期：2010-10-01 00:00:00

abstract：:Mus dunni endogenous virus (MDEV) is activated from cells of the Asian wild mouse M. dunni (also known as Mus terricolor) in response to treatment with either 5-iodo-2'-deoxyuridine or hydrocortisone. MDEV represents a new murine retrovirus interference group and thus appears to use a different receptor for entry into...

journal_title：Journal of virology

authors： Bonham L,Wolgamot G,Miller AD

更新日期：1997-06-01 00:00:00

abstract：:The widespread presence of endogenous retroviruses in the genomes of animals and humans has suggested that these viruses may be involved in both normal and abnormal developmental processes. Previous studies have indicated the involvement of endogenous ecotropic murine leukemia virus (MuLV) in the development of age-de...

journal_title：Journal of virology

authors： Contag CH,Plagemann PG

更新日期：1989-10-01 00:00:00

abstract：:Proteasomes are critical for the processing of antigens for presentation through the major histocompatibility complex (MHC) class I pathway. HIV-1 Gag protein is a component of several experimental HIV-1 vaccines. Therefore, understanding the processing of HIV-1 Gag protein and the resulting epitope repertoire is esse...

journal_title：Journal of virology

authors： Steers NJ,Currier JR,Kijak GH,di Targiani RC,Saxena A,Marovich MA,Kim JH,Michael NL,Alving CR,Rao M

更新日期：2011-02-01 00:00:00

abstract：:The 86-kDa IE-2 protein of human cytomegalovirus is able to autoregulate its own expression via a short nucleotide sequence, termed the cis repression signal (CRS), that is located between the TATA box and the cap site of the IE-1/2 enhancer-promoter. Here we report that the 86-kDa IE-2 protein can interact directly w...

journal_title：Journal of virology

authors： Lang D,Stamminger T

更新日期：1993-01-01 00:00:00

abstract：:The polypeptides of three paramyxoviruses (simian virus 5, Newcastle disease virus, and Sendai virus) were separated by polyacrylamide gel electrophoresis. Glycoproteins were identified by the use of radioactive glucosamine as a carbohydrate precursor. The protein patterns reveal similarities among the three viruses. ...

journal_title：Journal of virology

authors： Mountcastle WE,Compans RW,Choppin PW

更新日期：1971-01-01 00:00:00

abstract：:The pattern of induced protein species of the prototype strain of the parvovirus minute virus of mice was determined in permissive A9 mouse fibroblast cells by high-resolution two-dimensional gel electrophoresis. Identities of the viral proteins in the gels were assigned by probing two-dimensional blots with antisera ...

journal_title：Journal of virology

authors： Santarén JF,Ramírez JC,Almendral JM

更新日期：1993-09-01 00:00:00

abstract：:Herpes simplex virus (HSV)-infected cells can activate the human complement system without interference of specific anti-HSV antibodies. Analysis by flow cytometry showed that C3-like molecules were deposited on the membrane of the infected cell when incubated with human serum without specific antibodies. Depletion of...

journal_title：Journal of virology

authors： van Strijp JA,van Kessel KP,Miltenburg LA,Fluit AC,Verhoef J

更新日期：1988-03-01 00:00:00

abstract：:Borna disease virus (BDV) is a nonsegmented negative-strand (NNS) RNA virus that is unusual because it replicates in the nucleus. The most abundant viral protein in infected cells is a 38/39-kDa doublet that is presumed to represent the nucleocapsid. Infectious particles also contain high levels of this protein, accou...

journal_title：Journal of virology

authors： Pyper JM,Gartner AE

更新日期：1997-07-01 00:00:00

abstract：:Herpes simplex virus type 2 (HSV-2) glycoprotein B (gB-2) gene segments were expressed as recombinant proteins in Escherichia coli. gB-2 recombinant proteins were reacted with human serum immunoglobulin G (IgG) antibodies in Western immunoblot assays. Initially, samples were tested for the presence of HSV-1-specific a...

journal_title：Journal of virology

authors： Goade DE,Bell R,Yamada T,Mertz GJ,Jenison S

更新日期：1996-05-01 00:00:00

abstract：:Resolution of virus infections depends on the priming of virus-specific CD8+ T cells by dendritic cells (DC). While this process requires major histocompatibility complex (MHC) class I-restricted antigen presentation by DC, the relative contribution to CD8+ T cell priming by infected DC is less clear. We have addresse...

journal_title：Journal of virology

authors： Whitney PG,Makhlouf C,MacLeod B,Ma JZ,Gressier E,Greyer M,Hochheiser K,Bachem A,Zaid A,Voehringer D,Heath WR,Wagle MV,Parish I,Russell TA,Smith SA,Tscharke DC,Gebhardt T,Bedoui S

更新日期：2018-01-17 00:00:00

abstract：:The RNA genome of influenza virus is transcribed and replicated by the viral RNA polymerase complex in the cell nucleus. We have generated green fluorescent protein (GFP)-tagged polymerase subunits to study the assembly of the polymerase complex. Our results show that individually expressed polymerase basic protein 1 ...

journal_title：Journal of virology

authors： Fodor E,Smith M

更新日期：2004-09-01 00:00:00

abstract：:Human papillomavirus type 11 (HPV-11) and HPV-16 contain an E5 gene that can induce c-fos gene expression in mouse fibroblasts. This study investigated the human c-fos promoter characteristics by mapping the c-fos promoter sequence with several deletion and point mutants that confer responsiveness to E5 of HPV-11 or H...

journal_title：Journal of virology

authors： Chen SL,Lin YK,Li LY,Tsao YP,Lo HY,Wang WB,Tsai TC

更新日期：1996-12-01 00:00:00

abstract：:By using a series of deletion mutants, we have shown that the stimulation of fibroblast growth by E26 requires the cooperation of the two oncogenes, v-myb and v-ets, fused in the nuclear viral product. Of the two DNA-binding domains, only one must be present to promote anchorage-independent growth, whereas that of v-m...

journal_title：Journal of virology

authors： Ravel-Chapuis P,Leprince D,Pain B,Li R,Domenget C,Stehelin D,Samarut J,Jurdic P

更新日期：1991-07-01 00:00:00

abstract：:More than 200 open reading frames (ORFs) from the human cytomegalovirus genome have been reported as potentially coding for proteins. We have used two pattern-based in silico approaches to analyze this set of putative viral genes. With the help of an objective annotation method that is based on the Bio-Dictionary, a c...

journal_title：Journal of virology

authors： Rigoutsos I,Novotny J,Huynh T,Chin-Bow ST,Parida L,Platt D,Coleman D,Shenk T

更新日期：2003-04-01 00:00:00

abstract：:Broad, multispecific CD4(+) and CD8(+) T-cell responses to the hepatitis C virus (HCV), as well as virus-cross-neutralizing antibodies, are associated with recovery from acute infection and may also be associated in chronic HCV patients with a favorable response to antiviral treatment. In order to recapitulate all of ...

journal_title：Journal of virology

authors： Lin Y,Kwon T,Polo J,Zhu YF,Coates S,Crawford K,Dong C,Wininger M,Hall J,Selby M,Coit D,Medina-Selby A,McCoin C,Ng P,Drane D,Chien D,Han J,Vajdy M,Houghton M

更新日期：2008-08-01 00:00:00

abstract：UNLABELLED:Neutralizing antibodies that target the hemagglutinin of influenza virus either inhibit binding of hemagglutinin to cellular receptors or prevent the low-pH-induced conformational change in hemagglutinin required for membrane fusion. In general, the former type of antibody binds to the globular head formed b...

journal_title：Journal of virology

authors： Iba Y,Fujii Y,Ohshima N,Sumida T,Kubota-Koketsu R,Ikeda M,Wakiyama M,Shirouzu M,Okada J,Okuno Y,Kurosawa Y,Yokoyama S

更新日期：2014-07-01 00:00:00

abstract：:In some type C retroviruses, translation of the pol gene appears to require translational suppression of the proximal gag amber codon. To identify the region of the viral nucleic acid responsible for synthesis of the pol gene products, a 300-base-pair DNA fragment containing the stop codon from a type C murine virus (...

journal_title：Journal of virology

authors： Panganiban AT

更新日期：1988-10-01 00:00:00

abstract：:To study fundamental aspects of RNA recombination, an in vivo RNA recombination system was established. This system allowed the efficient generation of recombinant cytopathogenic pestiviruses after transfection of synthetic, nonreplicatable, subgenomic transcripts in cells infected with a replicating noncytopathogenic...

journal_title：Journal of virology

authors： Gallei A,Pankraz A,Thiel HJ,Becher P

更新日期：2004-06-01 00:00:00

abstract：:The poliovirus-encoded, membrane-associated VPg-precursor polypeptide 3AB has been implicated in the initiation of viral RNA synthesis. We have expressed 3AB and 3A polypeptides in eukaryotic cells and examined their localization using indirect immunofluorescence and a direct in vitro membrane-binding assay. Results p...

journal_title：Journal of virology

authors： Datta U,Dasgupta A

更新日期：1994-07-01 00:00:00

abstract：:A well-characterized mechanism by which anti-HLA class I monoclonal antibodies (MAb) inhibit human immunodeficiency virus type 1 (HIV-1) propagation in in vitro cell cultures is the neutralization of the virus through interactions with HLA molecules associated with the virion envelope. Yet, the possibility that anothe...

journal_title：Journal of virology

authors： Briant L,Benkirane M,Girard M,Hirn M,Iosef C,Devaux C

更新日期：1996-08-01 00:00:00

abstract：:A procedure has been developed for the isolation of Newcastle disease virus (NDV) envelope proteins. The two surface glycoproteins and the non-glycosylated membrane protein were solubilized with 2% Triton X-100 and 1 m KCl. Removal of the KCl by dialysis yielded by precipitation a pure preparation of the non-glycosyla...

journal_title：Journal of virology

authors： Scheid A,Choppin PW

更新日期：1973-02-01 00:00:00