Locations of herpes simplex virus type 2 glycoprotein B epitopes recognized by human serum immunoglobulin G antibodies.

abstract：:Mouse virus-like 30S RNAs (VL30m) constitute a family of retrotransposons, present at 100 to 200 copies, dispersed in the mouse genome. They display little sequence homology to Moloney murine leukemia virus (MoMLV), do not encode virus-like proteins, and have not been implicated in retroviral carcinogenesis. However, ...

journal_title：Journal of virology

authors： López-Lastra M,Ulrici S,Gabus C,Darlix JL

更新日期：1999-10-01 00:00:00

abstract：:We sequenced the leftmost 2,640 base pairs of bacteriophage P4 DNA, thus completing the sequence of the 11,627-base-pair P4 genome. The newly sequenced region encodes three nonessential genes, which are called gop, beta, and cII (in order, from left to right). The gop gene product kills Escherichia coli when the beta ...

journal_title：Journal of virology

authors： Ghisotti D,Finkel S,Halling C,Dehò G,Sironi G,Calendar R

更新日期：1990-01-01 00:00:00

abstract：:A distinct clinical presentation of respiratory syncytial virus (RSV) infection of humans is bronchiolitis, which has clinical features similar to those of asthma. Substance P (SP), a tachykinin neuropeptide, has been associated with neurogenic inflammation and asthma; therefore, we chose to examine SP-induced inflamm...

journal_title：Journal of virology

authors： Tripp RA,Moore D,Winter J,Anderson LJ

更新日期：2000-02-01 00:00:00

abstract：:The H-DNA repeat unit of Herpesvirus saimiri strain 11 was cloned in plasmid vector pAGO, and the nucleotide sequence was determined by the dideoxy chain termination method. One unit of repetitive DNA has 1,444 base pairs with 70.8% G+C content. The structural features of repeat DNA sequences at the termini of intact ...

journal_title：Journal of virology

authors： Bankier AT,Dietrich W,Baer R,Barrell BG,Colbère-Garapin F,Fleckenstein B,Bodemer W

更新日期：1985-07-01 00:00:00

abstract：:Four chimeric human immunodeficiency virus type 1 (HIV-1) env genes were constructed which encoded the extracellular domain of either the wild-type or a cleavage-defective HIV-1 envelope glycoprotein (gp160) fused at one of two different positions in env to a C-terminal glycosyl-phosphatidylinositol (GPI) attachment s...

journal_title：Journal of virology

authors： Salzwedel K,Johnston PB,Roberts SJ,Dubay JW,Hunter E

更新日期：1993-09-01 00:00:00

abstract：:We previously reported that mitogenic activation of porcine peripheral blood mononuclear cells resulted in production of porcine endogenous retrovirus(es) (PERV[s]) capable of productively infecting human cells (C. Wilson et al., J. Virol. 72:3082-3087, 1998). We now extend that analysis to show that additional passag...

journal_title：Journal of virology

authors： Wilson CA,Wong S,VanBrocklin M,Federspiel MJ

更新日期：2000-01-01 00:00:00

abstract：:Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA1) is indispensable for viral DNA replication and episome maintenance in latency. Four promoters, Cp, Wp, Qp, and Fp, are known to drive EBNA1 expression. Here we show that the TATA-less Qp is constitutively active in a variety of EBV-positive [EBV(+)] tumors and cell li...

journal_title：Journal of virology

authors： Tao Q,Robertson KD,Manns A,Hildesheim A,Ambinder RF

更新日期：1998-09-01 00:00:00

abstract：:The protein product of the v-myb oncogene of avian myeloblastosis virus, p48v-myb, differs structurally in several ways from its normal cellular homolog, p75c-myb. We demonstrated that the 11 specific amino acid substitutions found in two independent molecular clones of this virus were not required for the transformat...

journal_title：Journal of virology

authors： Stober-Grässer U,Lipsick JS

更新日期：1988-03-01 00:00:00

abstract：:Treatment of [3H]glucosamine-labeled Friend mink cell focus-forming virus (FrMCF) gp70 with excess peptide:N-glycanase F (PNGase F) resulted in removal of the expected seven N-linked oligosaccharide chains; however, approximately 10% of the glucosamine label was retained in the resulting 49,000-Mr (49K) product. For [...

journal_title：Journal of virology

authors： Pinter A,Honnen WJ

更新日期：1988-03-01 00:00:00

abstract：:Purified replicative form (RF) and replicative intermediate (RI) prepared from Escherichia coli cells infected with the ribonucleic acid (RNA) bacteriophage R17 were denatured with dimethyl sulfoxide at 37 C or in aqueous solvents of low ionic strength at 97 C. Denaturation was demonstrated for RF and RI by an increas...

journal_title：Journal of virology

authors： Franklin RM

更新日期：1967-06-01 00:00:00

abstract：:The human immunodeficiency virus type 1 Vpu protein is a 16-kDa phosphoprotein which enhances the efficiency of virion production and induces rapid degradation of CD4, the cellular receptor for human immunodeficiency virus. The topology of membrane-inserted Vpu was investigated by using in vitro-synthesized Vpu cotran...

journal_title：Journal of virology

authors： Maldarelli F,Chen MY,Willey RL,Strebel K

更新日期：1993-08-01 00:00:00

abstract：:Herpes simplex virus type 1 (HSV-1) DNA and RNA have been detected in peripheral nervous system (PNS) and central nervous system (CNS) tissues of latently infected mice. However, explant methods are successful in reactivating HSV-1 only from latently infected PNS tissues. In this report, latent herpesvirus infections ...

journal_title：Journal of virology

authors： Deatly AM,Spivack JG,Lavi E,O'Boyle DR 2nd,Fraser NW

更新日期：1988-03-01 00:00:00

abstract：:The N termini of the capsid proteins VP1 and VP2 of adeno-associated virus (AAV) play important roles in subcellular steps of infection and contain motifs that are highly homologous to a phospholipase A(2) (PLA(2)) domain and nuclear localization signals (NLSs). To more clearly understand how virion components influen...

journal_title：Journal of virology

authors： Johnson JS,Li C,DiPrimio N,Weinberg MS,McCown TJ,Samulski RJ

更新日期：2010-09-01 00:00:00

abstract：:Respiratory syncytial virus (RSV) is a major cause of severe lower respiratory tract disease in infants and the elderly, but no safe and effective RSV vaccine is yet available. For reasons that are not well understood, RSV is only weakly immunogenic, and reinfection occurs throughout life. This has complicated the sea...

journal_title：Journal of virology

authors： Martinez-Sobrido L,Gitiban N,Fernandez-Sesma A,Cros J,Mertz SE,Jewell NA,Hammond S,Flano E,Durbin RK,García-Sastre A,Durbin JE

更新日期：2006-02-01 00:00:00

abstract：:R325-beta TK+, a herpes simplex virus 1 mutant carrying a 500-base-pair deletion in the alpha 22 gene and the wild-type (beta) thymidine kinase (TK) gene, was previously shown to grow efficiently in HEp-2 and Vero cell lines. We report that in rodent cell lines exemplified by the Rat-1 line, plating efficiency was red...

journal_title：Journal of virology

authors： Sears AE,Halliburton IW,Meignier B,Silver S,Roizman B

更新日期：1985-08-01 00:00:00

abstract：:Four virion activities of Newcastle disease virus (hemagglutinating, neuraminidase, hemolytic, and infectious activities) were examined before and after heat stress in low-salt buffer and physiological salt buffer (phosphate-buffered saline). The hemagglutinating and neuraminidase activities of the Australia-Victoria ...

journal_title：Journal of virology

authors： Peeples ME,Glickman RL,Bratt MA

更新日期：1983-01-01 00:00:00

abstract：:The P4 promoter of the parvovirus minute virus of mice contains a single degenerate GC box sequence which binds the transcription factor Sp1 with high affinity. The two promoters of murine Sp1 were affinity purified, and their interactions with the P4 promoter were examined. Several unusual features were observed. Met...

journal_title：Journal of virology

authors： Pitluk ZW,Ward DC

更新日期：1991-12-01 00:00:00

abstract：:Among Moloney murine leukemia viruses (Mo-MuLVs) having stop codons other than UAG at the gag-pol junction, Mo-MuLV with UAA, but not with UGA, had a replication disadvantage. Mo-MuLV with a glutamine codon (CAG) at the junction did not replicate. A revertant of this virus consisted of the original virus and a virus w...

journal_title：Journal of virology

authors： Odawara T,Yoshikura H,Ohshima M,Tanaka T,Jones DS,Nemoto F,Kuchino Y,Iwamoto A

更新日期：1991-11-01 00:00:00

abstract：:All positive-strand RNA viruses reorganize host intracellular membranes to assemble their replication complexes. Similarly, brome mosaic virus (BMV) induces two alternate forms of membrane-bound RNA replication complexes: vesicular spherules and stacks of appressed double-membrane layers. The mechanisms by which these...

journal_title：Journal of virology

authors： Zhang J,Diaz A,Mao L,Ahlquist P,Wang X

更新日期：2012-05-01 00:00:00

abstract：:Marek's disease herpesvirus A antigen (MDHV-A) was identified as a 61,000- to 65,000-dalton glycoprotein by sodium dodecyl sulfate-polyacrylamide gel electrophoresis after immunoprecipitation from the culture medium of both [35S]methionine- and [14C]glucosamine-labeled infected cells by specific rabbit serum directed ...

journal_title：Journal of virology

authors： Glaubiger C,Nazerian K,Velicer LF

更新日期：1983-03-01 00:00:00

abstract：:Reoviruses are a leading model for understanding cellular mechanisms of virus-induced apoptosis. Reoviruses induce apoptosis in multiple cell lines in vitro, and apoptosis plays a key role in virus-induced tissue injury of the heart and brain in vivo. The activation of transcription factors NF-kappaB and c-Jun are key...

journal_title：Journal of virology

authors： DeBiasi RL,Clarke P,Meintzer S,Jotte R,Kleinschmidt-Demasters BK,Johnson GL,Tyler KL

更新日期：2003-08-01 00:00:00

abstract：UNLABELLED:The increasing number of zoonotic infections caused by influenza A virus (IAV) subtypes of avian origin (e.g., H5N1 and H7N9) in recent years underscores the need to better understand the factors driving IAV evolution and diversity. To evaluate the current feasibility of global analyses to contribute to this...

journal_title：Journal of virology

authors： Rejmanek D,Hosseini PR,Mazet JA,Daszak P,Goldstein T

更新日期：2015-11-01 00:00:00

abstract：:Coronaviruses that infect humans belong to the Alpha-coronavirus (including HCoV-229E) and Beta-coronavirus (including SARS-CoV and SARS-CoV-2) genera. In particular, SARS-CoV-2 is currently a major threat to public health worldwide. The spike (S) homotrimers bind to their receptors via the receptor-binding domain (RB...

journal_title：Journal of virology

authors： Shi Y,Shi J,Sun L,Tan Y,Wang G,Guo F,Hu G,Fu Y,Fu ZF,Xiao S,Peng G

更新日期：2021-01-07 00:00:00

abstract：:Feline herpesvirus produces characteristic morphological alterations in feline kidney cells. Nucleocapsid particles are formed in infected nuclei and are enveloped as they pass through the modified inner nuclear membrane. Aggregates of dense granular material and filamentous structures also regularly appear in infecte...

journal_title：Journal of virology

authors： Abraham A,Tegtmeyer P

更新日期：1970-05-01 00:00:00

abstract：:Zika virus (ZIKV) envelope (E) protein is the major target of neutralizing antibodies in infected hosts and thus represents a candidate of interest for vaccine design. However, a major concern in the development of vaccines against ZIKV and the related dengue virus is the induction of cross-reactive poorly neutralizin...

journal_title：Journal of virology

authors： De Lorenzo G,Tandavanitj R,Doig J,Setthapramote C,Poggianella M,Sanchez-Velazquez R,Scales HE,Edgar JM,Kohl A,Brewer J,Burrone OR,Patel AH

更新日期：2020-12-09 00:00:00

abstract：:Previously, the cyclophilin inhibitors cyclosporine (CsA) and alisporivir (ALV) were shown to inhibit the replication of diverse RNA viruses, including arteriviruses and coronaviruses, which both belong to the order Nidovirales In this study, we aimed to identify arterivirus proteins involved in the mode of action of ...

journal_title：Journal of virology

authors： de Wilde AH,Boomaars-van der Zanden AL,de Jong AWM,Bárcena M,Snijder EJ,Posthuma CC

更新日期：2019-08-28 00:00:00

abstract：UNLABELLED:Kaposi's sarcoma-associated herpesvirus (KSHV) is a human gammaherpesvirus with latent and lytic reactivation cycles. The mechanism by which KSHV evades the innate immune system to establish latency has not yet been precisely elucidated. Toll-like receptors (TLRs) are the first line of defense against viral ...

journal_title：Journal of virology

authors： Zhao Q,Liang D,Sun R,Jia B,Xia T,Xiao H,Lan K

更新日期：2015-01-01 00:00:00

abstract：:Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic agent of the aggressive and fatal disease adult T-cell leukemia. Previous studies have demonstrated that the HTLV-1-encoded Tax protein inhibits the function of tumor suppressor p53 through a Tax-induced NF-kappaB pathway. Given these attributes, we were int...

journal_title：Journal of virology

authors： Jung KJ,Dasgupta A,Huang K,Jeong SJ,Pise-Masison C,Gurova KV,Brady JN

更新日期：2008-09-01 00:00:00

abstract：:Among the five serine incorporator (SERINC) family members, SERINC5 (Ser5) was reported to strongly inhibit HIV-1 replication, which is counteracted by Nef. Ser5 produces 5 alternatively spliced isoforms: Ser5-001 has 10 putative transmembrane domains, whereas Ser5-004, -005, -008a, and -008b do not have the last one....

journal_title：Journal of virology

authors： Zhang X,Zhou T,Yang J,Lin Y,Shi J,Zhang X,Frabutt DA,Zeng X,Li S,Venta PJ,Zheng YH

更新日期：2017-04-28 00:00:00

abstract：:Autographa californica nuclear polyhedrosis virus (AcMNPV) is a double-stranded DNA virus that expresses several immediate-early genes under the control of different promoters. The expression of one of these transcription units, IE-N, is shown here, by a transient expression assay, to be regulated by both cis- and tra...

journal_title：Journal of virology

authors： Carson DD,Summers MD,Guarino LA

更新日期：1991-02-01 00:00:00