Role of depression, stress, and trauma in HIV disease progression.

Abstract:

:Despite advances in HIV treatment, there continues to be great variability in the progression of this disease. This paper reviews the evidence that depression, stressful life events, and trauma account for some of the variation in HIV disease course. Longitudinal studies both before and after the advent of highly active antiretroviral therapies (HAART) are reviewed. To ensure a complete review, PubMed was searched for all English language articles from January 1990 to July 2007. We found substantial and consistent evidence that chronic depression, stressful events, and trauma may negatively affect HIV disease progression in terms of decreases in CD4 T lymphocytes, increases in viral load, and greater risk for clinical decline and mortality. More research is warranted to investigate biological and behavioral mediators of these psychoimmune relationships, and the types of interventions that might mitigate the negative health impact of chronic depression and trauma. Given the high rates of depression and past trauma in persons living with HIV/AIDS, it is important for healthcare providers to address these problems as part of standard HIV care.

journal_name

Psychosom Med

journal_title

Psychosomatic medicine

authors

Leserman J

doi

10.1097/PSY.0b013e3181777a5f

subject

Has Abstract

pub_date

2008-06-01 00:00:00

pages

539-45

issue

5

eissn

0033-3174

issn

1534-7796

pii

PSY.0b013e3181777a5f

journal_volume

70

pub_type

杂志文章,评审
  • The relationship of interleukin-1 and immune functions to sleep in humans.

    abstract::Serial sampling of peripheral blood from six healthy adult male volunteers was performed during daytime waking and nighttime sleeping. In addition, sleep physiology was assessed in all subjects (Ss) and sleep stages scored blind by standard criteria. Samples of plasma were analyzed for cortisol (Co) levels, functional...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-198605000-00001

    authors: Moldofsky H,Lue FA,Eisen J,Keystone E,Gorczynski RM

    更新日期:1986-05-01 00:00:00

  • Prediction of daily food intake as a function of measurement modality and restriction status.

    abstract:OBJECTIVE:Research on eating relies on various indices (e.g., stable, momentary, neural) to accurately reflect food-related reactivity (e.g., disinhibition) and regulation (e.g., restraint) outside the laboratory. The degree to which they differentially predict real-world consumption remains unclear. Further, the predi...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0000000000000187

    authors: Giuliani NR,Tomiyama AJ,Mann T,Berkman ET

    更新日期:2015-06-01 00:00:00

  • Neural correlates of levels of emotional awareness during trauma script-imagery in posttraumatic stress disorder.

    abstract:OBJECTIVE:To examine individual differences in levels of emotional awareness as a predictor of the blood oxygenation level dependent (BOLD) response to trauma script-driven imagery in trauma-exposed individuals with (n = 25) and without (n = 16) posttraumatic stress disorder (PTSD). METHODS:Participants completed the ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e31815f66d4

    authors: Frewen P,Lane RD,Neufeld RW,Densmore M,Stevens T,Lanius R

    更新日期:2008-01-01 00:00:00

  • Neuroticism and cardiovascular disease mortality: socioeconomic status modifies the risk in women (UK Health and Lifestyle Survey).

    abstract:OBJECTIVE:The association between personality traits and mortality might differ as a function of socioeconomic status (SES). Our aim was to evaluate the all-cause, cardiovascular disease (CVD), and cancer mortality risk associated with neuroticism or extraversion and their interactions with SES in a representative samp...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e31825c85ca

    authors: Hagger-Johnson G,Roberts B,Boniface D,Sabia S,Batty GD,Elbaz A,Singh-Manoux A,Deary IJ

    更新日期:2012-07-01 00:00:00

  • Partner violence and psychological well-being: buffer or indirect effect of social support.

    abstract:OBJECTIVES:To determine the effect of two kinds of intimate partner violence (IPV) (physical and psychological) in the previous 12 months (current) and before the previous 12 months (past) on psychological well-being among women aged 18 to 70 years who attend primary healthcare centers in Spain; and to analyze the effe...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e3181d2f0dd

    authors: Escribà-Agüir V,Ruiz-Pérez I,Montero-Piñar MI,Vives-Cases C,Plazaola-Castaño J,Martín-Baena D,G6 for the Study of Gender Violence in Spain.

    更新日期:2010-05-01 00:00:00

  • Low Control and High Demands at Work as Risk Factors for Suicide: An Australian National Population-Level Case-Control Study.

    abstract:OBJECTIVE:Previous research suggests that psychosocial job stressors may be plausible risk factors for suicide. This study assessed the relationship between psychosocial job stressors and suicide mortality across the Australian population. METHODS:We developed a job exposure matrix to objectively measure job stressors...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0000000000000389

    authors: Milner A,Spittal MJ,Pirkis J,Chastang JF,Niedhammer I,LaMontagne AD

    更新日期:2017-04-01 00:00:00

  • Blood pressure response to the "second cup of coffee".

    abstract::Twenty young male coffee-drinkers consumed 150 mg of caffeine in decaffeinated coffee three times a day for 8 days. On days 3, 4, 7, and 8, caffeine or a placebo was administered in the laboratory at 11 A.M., 8 A.M., 11 A.M., and 8 A.M., respectively, in a randomized double-blind crossover design. There was a blood pr...

    journal_title:Psychosomatic medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00006842-199005000-00007

    authors: Goldstein IB,Shapiro D,Hui KK,Yu JL

    更新日期:1990-05-01 00:00:00

  • Insomnia and depression prior to myocardial infarction.

    abstract::Insomnia is common among patients who subsequently experience an acute myocardial infarction (MI), and is a major symptom of psychiatric depression. The purpose of this study was to determine what proportion of patients reporting insomnia prior to MI have depression. Of 70 patients with a recent MI, 27 (39%) reported ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199011000-00001

    authors: Carney RM,Freedland KE,Jaffe AS

    更新日期:1990-11-01 00:00:00

  • Electrophysiologic characteristics of respiratory suspension periods occurring during the practice of the Transcendental Meditation Program.

    abstract::In a study designed to identify the electrophysiologic characteristics of the Transcendental Meditation Program, 52 periods of spontaneous respiratory suspension (RS) were observed in 18 subjects during the practice of this program. These periods were correlated with some but not all the subjective experiences of pure...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-198405000-00008

    authors: Badawi K,Wallace RK,Orme-Johnson D,Rouzere AM

    更新日期:1984-05-01 00:00:00

  • Personality characteristics, body image and social attitudes of organ transplant donors versus nondonors.

    abstract::Thirty adults willing their body at death to medical science were compared on a number of personality variables with 30 nondonors, both groups equated for age, education, and socioeconomic status. Donors are internally directed, masters of their fate; nondonors rely on chance or luck to explain outcome. A more defin...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-197507000-00004

    authors: Cleveland SE

    更新日期:1975-07-01 00:00:00

  • Relationship between work stress and body mass index among 45,810 female and male employees.

    abstract:OBJECTIVE:The proportion of overweight and obese people has grown rapidly, and obesity has now been widely recognized as an important public health problem. At the same time, stress has increased in working life. The 2 problems could be connected if work stress promotes unhealthy eating habits and sedentary behavior an...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/01.psy.0000170330.08704.62

    authors: Kouvonen A,Kivimäki M,Cox SJ,Cox T,Vahtera J

    更新日期:2005-07-01 00:00:00

  • Socioeconomic Position and Antidepressant Use as Predictors of Coronary Heart Disease Mortality: A Population-Based Registry Study of 362,271 Finns.

    abstract:OBJECTIVE:The interplay between depression and socioeconomic position (SEP) in predicting cardiovascular outcomes has rarely been examined. We investigated whether SEP modified the effect of antidepressant use on coronary heart disease (CHD) mortality. METHODS:The data consisted of an 11% random sample of the Finnish ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0000000000000258

    authors: Konttinen H,Kilpi F,Moustgaard H,Martikainen P

    更新日期:2016-02-01 00:00:00

  • Classical conditioning of insulin effects in healthy humans.

    abstract:OBJECTIVE:Classical conditioning of insulin effects was examined in healthy humans using a placebo-controlled design. This study examined whether subjects who experienced a conditioned stimulus (CS) paired with insulin in the acquisition phase of a conditioning protocol would show a conditioned decrease of blood glucos...

    journal_title:Psychosomatic medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00006842-199907000-00004

    authors: Stockhorst U,Gritzmann E,Klopp K,Schottenfeld-Naor Y,Hübinger A,Berresheim HW,Steingrüber HJ,Gries FA

    更新日期:1999-07-01 00:00:00

  • Impaired central processing of emotional faces in anorexia nervosa.

    abstract:OBJECTIVES:To elucidate the potential relationship between classification of emotional faces and impaired central processing in eating disorders and to investigate the potential mediatory role of alexithymia and depression in this relationship. METHODS:Visual-evoked potentials (VEPs) to emotional faces and classificat...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e31817e41e6

    authors: Pollatos O,Herbert BM,Schandry R,Gramann K

    更新日期:2008-07-01 00:00:00

  • Diagnostic groups and depressed mood as predictors of 22-month mortality in medical inpatients.

    abstract:OBJECTIVE:While depression has been found to predict mortality in acute myocardial infarction, results from many other groups of medical patients are inconclusive. It is, therefore, unclear whether depression also predicts mortality in the typical mixed patient populations treated on medical hospital wards and whether ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199809000-00011

    authors: Herrmann C,Brand-Driehorst S,Kaminsky B,Leibing E,Staats H,Rüger U

    更新日期:1998-09-01 00:00:00

  • Depressed mood and flow-mediated dilation: a systematic review and meta-analysis.

    abstract:OBJECTIVE:This systematic and quantitative review evaluates the literature on associations between depressed mood and flow-mediated dilation (FMD), a measure of endothelial function, in adults. METHODS:Published English-language articles (through December 2010) were identified from literature searches, assessed for da...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/PSY.0b013e31821db79a

    authors: Cooper DC,Tomfohr LM,Milic MS,Natarajan L,Bardwell WA,Ziegler MG,Dimsdale JE

    更新日期:2011-06-01 00:00:00

  • Divorce and health: current trends and future directions.

    abstract:OBJECTIVE:Social relationships play a vital role in health and well-being, and it follows that loss experiences can be highly stressful for some people. This article reviews what is known about the association between marital separation, divorce, and health outcomes. METHODS:Key findings in the area of divorce and hea...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章,评审

    doi:10.1097/PSY.0000000000000168

    authors: Sbarra DA

    更新日期:2015-04-01 00:00:00

  • Blood pressure, ethnicity, and psychosocial resources.

    abstract::Research on psychosocial factors and cardiovascular disease has shown that psychosocial resources (including social supports and coping styles) help to protect individuals from the risk associated with psychosocial stressors. Some evidence indicates that this protective effect may extend to standard risk factors as we...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-198609000-00006

    authors: Dressler WW,Dos Santos JE,Viteri FE

    更新日期:1986-09-01 00:00:00

  • Respiratory airway changes in response to suggestion in normal individuals.

    abstract::Thirty normal individuals were told they were inhaling a substance that would either cause breathing difficulty (N = 15) or not affect breathing (N = 15). Total respiratory resistance was measured prior to and during inhalation. In reality, the subjects inhaled no substance; inhalation consisted of breathing normally ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-198709000-00009

    authors: Kotses H,Rawson JC,Wigal JK,Creer TL

    更新日期:1987-09-01 00:00:00

  • Socioeconomic status, antioxidant micronutrients, and correlates of oxidative damage: the Coronary Artery Risk Development in Young Adults (CARDIA) study.

    abstract:OBJECTIVE:To examine whether socioeconomic status (SES) (education, occupation, income), is associated both cross sectionally and prospectively with circulating concentrations of a) two correlates of oxidative damage, F(2)-isoprostanes (F(2)-IsoPs) and gamma-glutamyltransferase (GGT); and b) antioxidant nutrients (asco...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e31819e7526

    authors: Janicki-Deverts D,Cohen S,Matthews KA,Gross MD,Jacobs DR Jr

    更新日期:2009-06-01 00:00:00

  • Heart rate reactivity as a predictor of neuroendocrine responses to aversive and appetitive challenges.

    abstract::The present paper examines the neuroendocrine influences of aversive and reward incentives (noise and shock versus monetary bonuses) presented during reaction time tasks administered to 71 healthy men (ages 21 to 35) classified as being high (N = 30) or low (N = 41) in heart rate reactivity. High heart rate reactivity...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199001000-00002

    authors: Lovallo WR,Pincomb GA,Brackett DJ,Wilson MF

    更新日期:1990-01-01 00:00:00

  • Brain Structure and Response to Emotional Stimuli as Related to Gut Microbial Profiles in Healthy Women.

    abstract:OBJECTIVE:Brain-gut-microbiota interactions may play an important role in human health and behavior. Although rodent models have demonstrated effects of the gut microbiota on emotional, nociceptive, and social behaviors, there is little translational human evidence to date. In this study, we identify brain and behavior...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0000000000000493

    authors: Tillisch K,Mayer EA,Gupta A,Gill Z,Brazeilles R,Le Nevé B,van Hylckama Vlieg JET,Guyonnet D,Derrien M,Labus JS

    更新日期:2017-10-01 00:00:00

  • Adjustment in diabetic adolescent girls: II. Adjustment, self-esteem, and depression in diabetic adolescent girls.

    abstract::The Rosenberg Self-Esteem Scale, Beck Depression Inventory, and Sullivan Diabetic Adjustment Scale were administered to 105 adolescent girls with diabetes. Results indicate that levels of self-esteem and depression highly correlate with the level of adjustment as assessed on the Diabetic Adjustment Scale (DAS). That i...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-197903000-00006

    authors: Sullivan BJ

    更新日期:1979-03-01 00:00:00

  • The influence of stress intrusion on immunodepression in generalized anxiety disorder patients and controls.

    abstract::Previous work from our group has examined the relationship between stress and immunodepression in medical students taking National Boards, Part I, and has described a relationship between stress intrusion scores (SIS) and immunodepression. We have also shown that a high proportion of individuals with generalized anxie...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199603000-00007

    authors: La Via MF,Munno I,Lydiard RB,Workman EW,Hubbard JR,Michel Y,Paulling E

    更新日期:1996-03-01 00:00:00

  • Transforming Pain With Prosocial Meaning: A Functional Magnetic Resonance Imaging Study.

    abstract:OBJECTIVE:Contextual factors can transform how we experience pain, particularly if pain is associated with other positive outcomes. Here, we test a novel meaning-based intervention. Participants were given the opportunity to choose to receive pain on behalf of their romantic partners, situating pain experience in a pos...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0000000000000609

    authors: López-Solà M,Koban L,Wager TD

    更新日期:2018-11-01 00:00:00

  • Placebo Effects in the Neuroendocrine System: Conditioning of the Oxytocin Responses.

    abstract:OBJECTIVE:There is evidence that placebo effects may influence hormone secretion. However, few studies have examined placebo effects in the endocrine system, including oxytocin placebo effects. We studied whether it is possible to trigger oxytocin placebo effects using a classical conditioning paradigm. METHODS:Ninety...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0000000000000759

    authors: Skvortsova A,Veldhuijzen DS,Pacheco-Lopez G,Bakermans-Kranenburg M,van IJzendoorn M,Smeets MAM,Wilderjans TF,Dahan A,van den Bergh O,Chavannes NH,van der Wee NJA,Grewen KM,van Middendorp H,Evers AWM

    更新日期:2020-01-01 00:00:00

  • Higher abnormal leukocyte and lymphocyte counts 20 years after exposure to severe stress: research and clinical implications.

    abstract:OBJECTIVES:Research suggests that individuals with posttraumatic stress disorder (PTSD) are more likely to develop medical conditions and other stress-related psychiatric disorders. Given these findings and others suggesting that PTSD victims may have altered neuroendocrine and immune systems, the hypothesis that Vietn...

    journal_title:Psychosomatic medicine

    pub_type: 临床试验,杂志文章

    doi:10.1097/00006842-199905000-00019

    authors: Boscarino JA,Chang J

    更新日期:1999-05-01 00:00:00

  • Type D personality, self-efficacy, and medication adherence following an acute coronary syndrome.

    abstract:OBJECTIVE:To assess the relationship among Type D personality, self-efficacy, and medication adherence in patients with coronary heart disease. METHODS:The study design was prospective and observational. Type D personality, self-efficacy for illness management behaviors, and medication adherence were measured 3 weeks ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e31823a5b2f

    authors: Molloy GJ,Randall G,Wikman A,Perkins-Porras L,Messerli-Bürgy N,Steptoe A

    更新日期:2012-01-01 00:00:00

  • Short Sleep Duration After Hospital Evaluation for Acute Coronary Syndrome Is Associated With Increased Risk of 6-Month Readmission.

    abstract:OBJECTIVE:Hospital readmission after acute coronary syndrome (ACS) is associated with worsened patient outcomes and financial burden. Short sleep duration is a risk factor for cardiovascular events and may therefore represent a behavioral factor that increases risk of adverse posthospitalization outcomes. This study ex...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0000000000000730

    authors: Romero EK,Abdalla M,Thanataveerat A,Alcantara C,Kronish IM,Edmondson D,Shechter A

    更新日期:2020-01-01 00:00:00

  • Insulin and glucose: relationships with hassles, anger, and hostility in nondiabetic older adults.

    abstract::Relationships of psychosocial factors (anger, hostility, hassles, and caregiving) with fasting insulin and glucose levels were examined. Samples included two groups of nondiabetic adults (mean age = 69.4 years): spouse caregivers (CG) of individuals with diagnoses of Alzheimer's disease (AD) (N = 78) and spouses of no...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199609000-00011

    authors: Vitaliano PP,Scanlan JM,Krenz C,Fujimoto W

    更新日期:1996-09-01 00:00:00