Abstract:
:Serial sampling of peripheral blood from six healthy adult male volunteers was performed during daytime waking and nighttime sleeping. In addition, sleep physiology was assessed in all subjects (Ss) and sleep stages scored blind by standard criteria. Samples of plasma were analyzed for cortisol (Co) levels, functional interleukin-1 (IL-1), and interleukin-2 (IL-2) activity. Peripheral blood monocytes (PBM) were assayed to evaluate natural killer (NK) activity and mitogen responsiveness. Dramatic increase in IL-1 activity along with changes in other immune functions occurred during sleep and were related to onset of slow wave sleep.
journal_name
Psychosom Medjournal_title
Psychosomatic medicineauthors
Moldofsky H,Lue FA,Eisen J,Keystone E,Gorczynski RMdoi
10.1097/00006842-198605000-00001subject
Has Abstractpub_date
1986-05-01 00:00:00pages
309-18issue
5eissn
0033-3174issn
1534-7796journal_volume
48pub_type
杂志文章abstract:OBJECTIVE:Classical conditioning of insulin effects was examined in healthy humans using a placebo-controlled design. This study examined whether subjects who experienced a conditioned stimulus (CS) paired with insulin in the acquisition phase of a conditioning protocol would show a conditioned decrease of blood glucos...
journal_title:Psychosomatic medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00006842-199907000-00004
更新日期:1999-07-01 00:00:00
abstract:OBJECTIVE:A previous study suggested that insulin metabolic variables play a role in the progression of atherosclerosis in Watanabe heritable hyperlipidemic (WHHL) rabbits. The present study sought to determine: 1) if young, individually caged WHHLs are insulin-resistant relative to New Zealand white (NZW) rabbits and ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000155674.95497.ab
更新日期:2005-03-01 00:00:00
abstract::A multidimensional behavioral program was developed for the treatment of essential hypertension. Over a course of 6 weeks, 108 patients of a rehabilitation center were treated with this program consisting of health education, self-monitoring of blood pressure, relaxation techniques, and a social skill training in addi...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-198707000-00011
更新日期:1987-07-01 00:00:00
abstract::MMPI measures of neuroticism (N) and of cynicism (C) were obtained at the initial examination of 1871 employed, middle-aged men in Chicago. Neither N nor C was significantly associated cross-sectionally with systolic blood pressure or serum cholesterol, but both were positively associated with cigarette smoking and al...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-199103000-00006
更新日期:1991-03-01 00:00:00
abstract::This study was conducted to test the hypothesis that patients with MI are distinguished from persons with a less serious illness, more by subjective interpretations of the emotional impact of life events than by exposure to a surfeit of life events that purportedly representative samples of the population have judged ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-198001000-00001
更新日期:1980-01-01 00:00:00
abstract:OBJECTIVES:We sought to determine whether irritable bowel syndrome (IBS) was associated with attentional bias toward symptom-related cues in IBS patients versus healthy controls, using a modified Stroop task to measure selective processing of gastrointestinal symptom-related cues. METHODS:Fifteen patients with a clini...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000232270.78071.28
更新日期:2006-09-01 00:00:00
abstract:OBJECTIVE:We investigated whether perception of subjective asthma symptoms can be brought under control of biomedically irrelevant cues in the environment, i.e., whether subjective asthma symptoms can be learned in response to harmless stimuli. METHODS:Twenty patients with asthma and 20 healthy participants were prese...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000160470.43167.e2
更新日期:2005-05-01 00:00:00
abstract:OBJECTIVE:Accumulating evidence indicates the beneficial effects of positive emotion on health and general well-being in older age. Less evidence is available on whether positive emotion supports improvement in functional status after an acute medical event such as stroke. This study examined the association between po...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e31816fd7d0
更新日期:2008-05-01 00:00:00
abstract:OBJECTIVE:To examine whether socioeconomic status (SES) (education, occupation, income), is associated both cross sectionally and prospectively with circulating concentrations of a) two correlates of oxidative damage, F(2)-isoprostanes (F(2)-IsoPs) and gamma-glutamyltransferase (GGT); and b) antioxidant nutrients (asco...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e31819e7526
更新日期:2009-06-01 00:00:00
abstract:OBJECTIVE:We examined whether depression is independently associated with implantable cardioverter defibrillator (ICD) therapy for ventricular tachyarrhythmias and mortality. METHODS:A cohort of 430 consecutive patients with a first-time ICD (79% men; mean [standard deviation] age = 57.8 [12.1] years) completed the Ho...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000017
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVES:Our objectives were to test whether Conscientiousness, the other 4 domains of the Five-Factor Model, and their facets predicted mortality in older, frail individuals. METHODS:Controlling for demographic and health measures, we used Cox regression to test whether the NEO Five-Factor Inventory (NEO-FFI) Neuro...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000181272.58103.18
更新日期:2005-09-01 00:00:00
abstract:OBJECTIVE:To investigate the association between vitamin D deficiency and depressive symptoms in a national community sample of older people. Vitamin D deficiency is common in older people with potential effects on mood. METHODS:Data were analyzed from 2070 participants aged ≥65 years who had participated in the 2005 ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e3181e9bf15
更新日期:2010-09-01 00:00:00
abstract:OBJECTIVES:Lesbian, gay, and bisexual (LGB) individuals-particularly those who have not disclosed their sexual orientation-are believed to experience increased chronic stress in comparison with heterosexuals. This interdisciplinary study assessed whether psychiatric symptoms (self-rated anxiety, depression, and burnout...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e3182826881
更新日期:2013-02-01 00:00:00
abstract:OBJECTIVE:This study evaluated the ability of mental stress testing to discriminate between women with and without CHD, and among women with different disease manifestations, taking into account history of hypertension and beta-blocker use. METHODS:Analyses were based on data from a community-based case-control study ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-200111000-00010
更新日期:2001-11-01 00:00:00
abstract:OBJECTIVE:To examine the hypothesis that young adults with major depressive disorder (MDD) would show increased affective bias to painful and nonpainful experimental heat stimuli, as evidenced by an increased responsiveness to warm and hot temperatures. Pain and depression often occur together. Pain is both a sensation...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e3181656a48
更新日期:2008-04-01 00:00:00
abstract:OBJECTIVE:To examine the association of anxiety with incident dementia and cognitive impairment not dementia (CIND). METHODS:We conducted a prospective study of men aged 48 to 67 years at baseline anxiety assessment; we measured cognition 17 years later. We studied 1481 men who were either eligible for examination or ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e3181a6177c
更新日期:2009-07-01 00:00:00
abstract:OBJECTIVE:We examined whether high waist-to-hip ratio (WHR) in women is a biomarker for increased testosterone (T) and higher levels of sexual desire. METHODS:Participants were 99 healthy nonobese premenopausal women. Trait levels of mean bioavailable T were estimated from three saliva samples collected at 8:00 am, 9:...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000151747.22904.d7
更新日期:2005-03-01 00:00:00
abstract:OBJECTIVE:To investigate the modifying effects of two candidate genes (serotonin transporter gene linked promoter region (5-HTTLPR) and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphisms) on the associations between general somatic morbidity and incidence of depression in an East Asian population with high...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e3181990fff
更新日期:2009-04-01 00:00:00
abstract:OBJECTIVES:To elucidate the potential relationship between classification of emotional faces and impaired central processing in eating disorders and to investigate the potential mediatory role of alexithymia and depression in this relationship. METHODS:Visual-evoked potentials (VEPs) to emotional faces and classificat...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e31817e41e6
更新日期:2008-07-01 00:00:00
abstract:OBJECTIVES:Exposure is regarded to be a crucial component of therapies for phobias. According to emotional processing theory, the success of exposure therapy is predicted by activation of subjective and physiological fear responses and their within-session habituation and between-session adaptation. This study tested t...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000209
更新日期:2015-09-01 00:00:00
abstract:OBJECTIVE:Cancer-related distress due to the psychological and physical challenges of metastatic breast cancer (MBC) may result in symptoms of depression, which negatively affects quality and may influence quantity of life. This study investigated how depression affects MBC stress reactivity, including autonomic (ANS) ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000238216.88515.e5
更新日期:2006-09-01 00:00:00
abstract::Using a prospective design, this study examined the hypothesis that a predisposition to focus on internal aspects of the self serves as a stress resistance resource. One hundred and twenty subjects filled out the Private Self-Consciousness inventory, a schedule of recent life events and a symptom checklist. Two months...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-198509000-00007
更新日期:1985-09-01 00:00:00
abstract:OBJECTIVES:Agency has been conceptualized as a drive toward mastery, control, and effective self-management. Such an agentic approach to life and its challenges may be life-prolonging, a hypothesis not previously investigated. METHOD:In four studies, individual differences in agency were assessed in terms of the frequ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000337
更新日期:2016-09-01 00:00:00
abstract:OBJECTIVE:Posttraumatic stress disorder (PTSD) is associated with indicators of poor physical health and sleep disturbance. This study investigated the relationship between PTSD and metabolic risk factors and examined the role of sleep duration in medically healthy and medication-free adults. METHODS:Participants with...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000176
更新日期:2015-05-01 00:00:00
abstract:OBJECTIVE:This study examines whether stressful negative life events and pessimism were associated with lower natural killer cell cytotoxicity (NKCC) and T cytotoxic/suppressor cell (CD8+CD3+) percentage in black women co-infected with human immunodeficiency virus Type 1 (HIV-1) and human papillomavirus (HPV), a viral ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-199811000-00009
更新日期:1998-11-01 00:00:00
abstract:OBJECTIVE:This study examined the genetic and environmental contributions to the individual differences in blood pressure (BP) levels and underlying hemodynamic characteristics at rest and during mental challenge tasks in a large twin cohort of youth. Including both European American and African American twins further ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e31828d3cb6
更新日期:2013-05-01 00:00:00
abstract::This study compared the neurobehavioral performance of hypertensive and normotensive men and women using neuropsychological, information-processing, and psychometric assessments. One hundred subjects, including 68 hypertensive and 32 normotensive individuals, completed a test battery that yielded scores on measures of...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-199301000-00008
更新日期:1993-01-01 00:00:00
abstract:OBJECTIVE:Hospital readmission after acute coronary syndrome (ACS) is associated with worsened patient outcomes and financial burden. Short sleep duration is a risk factor for cardiovascular events and may therefore represent a behavioral factor that increases risk of adverse posthospitalization outcomes. This study ex...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000730
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:This study was conducted to confirm the definition of multiple chemical sensitivity (MCS) in actual life: that multiple symptoms are provoked in multiple organs by exposure to, and ameliorated by avoidance of, multiple chemicals at low levels. We used the Ecological Momentary Assessment to monitor everyday sy...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000155676.69030.28
更新日期:2005-03-01 00:00:00
abstract::Thirty normal-weight female bulimics were followed up 2-5 years following hospital admission using semistructured interviews and psychometric measures. Inasmuch as bulimia was only recently designated a distinct disorder, questions have emerged with regard to its clinical course and diagnostic validity. Results of thi...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-198701000-00004
更新日期:1987-01-01 00:00:00