Abstract:
:Topical ketoconazole (2% ointment three times per day for three weeks) markedly reduced the severity of keratitis produced with Candida albicans inoculation in the right eyes of 20 rabbits. Clinical scores of affected eyes were significantly lower in the treated eyes than in the controls, which consisted of the 20 inoculated but untreated left eyes of the same rabbits. All cultures of corneal scrapings from the treated eyes were negative on the 12th day after inoculation, while two cultures were still positive at the end of the experiment (day 21) in the control eyes. Histopathologic examination showed less severe inflammatory changes in the treated eyes than in the control eyes.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Ishibashi Y,Kaufman HEdoi
10.1016/0002-9394(86)90084-xsubject
Has Abstractpub_date
1986-10-15 00:00:00pages
522-6issue
4eissn
0002-9394issn
1879-1891pii
0002-9394(86)90084-Xjournal_volume
102pub_type
杂志文章abstract::A patient sustained mild bilateral alkali burns of the cornea following ocular exposure to a commercial hair straightening preparation. This compound and three other products all had an alkaline pH which was not reduced to neutrality by the neutralizer provided. Corneal alkali burns similar to those seen in our patien...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(75)90799-0
更新日期:1975-04-01 00:00:00
abstract:PURPOSE:To study the prevalence and risk factors of intraocular pressure (IOP) elevation and refractory IOP elevation after a single 4 mg intravitreal triamcinolone acetonide (IVTA) injection in a Chinese population. DESIGN:Retrospective, observational case series. METHODS:Retrospective chart review of all the patien...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2008.05.034
更新日期:2008-10-01 00:00:00
abstract::A 4-year-old boy had a case of ischemic infarction of the retina that occurred immediately after percutaneous carotoid angiography via a femoral percutaneous approach. This appears to be the youngest reported patient with this complication. ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(76)90203-8
更新日期:1976-01-01 00:00:00
abstract:PURPOSE:To study the correlation between posterior capsule opacification (PCO) and intraocular straylight and visual acuity. DESIGN:Prospective noninterventional study. METHODS:We measured visual acuity (VA), logarithm of minimal angle of resolution (logMAR) and intraocular straylight (C-Quant straylight parameter lo...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2010.02.026
更新日期:2010-08-01 00:00:00
abstract:PURPOSE:We report a case of a submacular surgery complicated by a choroidal neovascular membrane at the retinotomy site. METHOD:The patient underwent submacular surgery for the removal of an idiopathic choroidal neovascular membrane. RESULT:Three weeks after surgery, the patient developed a choroidal neovascular memb...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)70499-4
更新日期:1996-11-01 00:00:00
abstract:PURPOSE:Current screening of potential corneal donors for human immunodeficiency virus type 1 (HIV-1) involves serologic detection of antibodies to the virus. However, this approach cannot detect infection during the seronegative window period of the disease. We therefore evaluated the polymerase chain reaction (PCR) a...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)72113-0
更新日期:1996-10-01 00:00:00
abstract:PURPOSE:To report on the clinical manifestations, complications, and long-term visual prognosis of patients with peripheral multifocal chorioretinitis and to search for predictors for a lower visual outcome. DESIGN:Retrospective consecutive observational case series. METHODS:setting: Institutional. PATIENT POPULATIO...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2015.01.005
更新日期:2015-04-01 00:00:00
abstract:PURPOSE:To evaluate the postoperative status of the macula after vitreous surgery with internal limiting membrane removal for macular hole related retinal detachment in patients with severe myopia. DESIGN:Interventional case series. METHODS:We prospectively examined 10 eyes with retinal detachment associated with a m...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(03)00186-7
更新日期:2003-08-01 00:00:00
abstract::In 11 of 12 eyes with chronic simple glaucoma after surgery for retinal detachment, intraocular pressures were decreased for one to 5 1/2 years without any antiglaucomatous treatment. No further deterioration in the state of the optic disks or the visual fields occurred in any of these eyes. In all 12 fellow eyes anti...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(75)90403-1
更新日期:1975-10-01 00:00:00
abstract:PURPOSE:To investigate the effect of shorter axial length on the laser spot size and laser energy during photodynamic therapy (PDT) in monkeys. DESIGN:Experimental study with four rhesus monkeys. METHODS:PDT was performed on the normal retina of monkeys whose ocular axial lengths are shorter (19.55 to 20.25 mm) than ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2005.08.016
更新日期:2006-01-01 00:00:00
abstract:PURPOSE:To treat a 30-year-old man with a ventriculoperitoneal shunt who had progressive visual loss. METHODS:The patient underwent computed tomographic and magnetic resonance imaging scans and ocular examination. RESULTS:He was diagnosed with ventriculoperitoneal shunt failure despite the lack of ventriculomegaly on...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)71980-4
更新日期:1996-07-01 00:00:00
abstract:PURPOSE:To report a case of neonatal orbital ganglioglioma originating from ectopic neural tissue. METHOD:Case report. RESULTS:An African-American male presented at birth with proptosis and expansion of the left orbit. A discrete soft-tissue mass was located inferolateral to the globe, which proved to be a gangliogli...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(99)00288-3
更新日期:2000-01-01 00:00:00
abstract:PURPOSE:To document a case of Candida tropicalis endophthalmitis as the only manifestation of pacemaker endocarditis. METHODS:We examined a 75-year-old man with diabetes mellitus who was initially examined for bilateral multifocal endophthalmitis complicating endocarditis 2 years after a permanent pacemaker for sick s...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)70189-8
更新日期:1997-04-01 00:00:00
abstract:PURPOSE:To assess the optic nerve head (ONH) by optical coherence tomography (OCT), confocal scanning laser ophthalmoscopy (CSLO), and the retinal nerve fiber layer (RNFL) by OCT and scanning laser polarimetry (GDx) in highly myopic subjects. DESIGN:Observational cross-sectional study. METHODS:Thirty-five eyes of hig...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2006.05.022
更新日期:2006-11-01 00:00:00
abstract::We treated five patients with vestibular neuritis who had strabismus. Three of them spontaneously noted vertical diplopia. During the following weeks and months, strabismus progressively resolved, indicating the recently acquired nature of the oculomotor condition. In three of these individuals, a change in visual ver...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)72904-6
更新日期:1994-08-15 00:00:00
abstract:PURPOSE:To establish a rat model of acute increase in intraocular pressure (IOP) and to investigate the therapeutic window for protection against death of retinal ganglion cells (RGCs) by vaccination with glatiramer acetate (Cop-1) or by treatment with brimonidine or MK-801. DESIGN:Animal study, laboratory investigati...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2006.01.073
更新日期:2006-06-01 00:00:00
abstract::We studied 216 eyes of 160 patients who underwent combined phacoemulsification and posterior chamber intraocular lens implantation with trabeculectomy. The mean follow-up was 18.7 months, with a minimum follow-up of six months. To assess the safety and efficacy of a recently developed 3-mm incision procedure with fold...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)72258-5
更新日期:1991-02-15 00:00:00
abstract:PURPOSE:To evaluate the relationship between β-zone parapapillary atrophy (βPPA) and corneal hysteresis (CH) in patients with glaucoma. DESIGN:Prospective, cross-sectional study. METHODS:Glaucoma patients aged 18 to 90 years with disc photographs within 12 months of the study visit were consecutively enrolled. Exclus...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2011.06.025
更新日期:2012-02-01 00:00:00
abstract::In 18 patients, 2% pilocarpine, 2% pilocarpine plus tropicamide 10:1, and 2% aceclidine were tested with respect to the degree of spasm of accommodation induced by these drugs. Aceclidine had the least effect on accommodation, making it the recommended drug for use in patients with glaucoma and considerable remaining ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(75)90464-x
更新日期:1975-01-01 00:00:00
abstract::We studied the postmortem histologic characteristics of two eyes that had undergone penetrating keratoplasty and transscleral suturing of a posterior chamber intraocular lens for bullous keratopathy. The eyes were studied three days postoperatively in a 79-year-old man with pseudophakia and six months postoperatively ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)76337-8
更新日期:1990-09-15 00:00:00
abstract::We used peripheral retinal cryopexy to treat 20 eyes in 15 patients with subtotal vitreous hemorrhage secondary to proliferative diabetic retinopathy. In 18 eyes, complete panretinal photocoagulation had been performed before the subtotal vitreous hemorrhage and the subsequent cryopexy. The length of follow-up average...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(88)90301-7
更新日期:1988-04-15 00:00:00
abstract::Dipivefrin, an epinephrine prodromal drug, was used in conjunction with timolol maleate to evaluate the safety and effectiveness of combined therapy. Seventeen patients who had used timolol maleate for at least six months added dipivefrin (Group 1) and seven patients who had used dipivefrin for at least six months add...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(81)90182-3
更新日期:1981-02-01 00:00:00
abstract:PURPOSE:An association of glaucoma and sleep apnea syndrome (SAS) has been widely reported. We investigated the largest group of patients with SAS thus far to determine the prevalence of glaucoma among these patients. DESIGN:Cross-sectional study. METHODS:An institutional study. STUDY POPULATION:A total of 228 patie...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(03)00709-8
更新日期:2003-12-01 00:00:00
abstract::We treated 84 patients with a partially refractive accommodative esotropia with bifocals. Twelve patients were able to fuse without bifocals at the end of therapy; in 19, the bifocal power could be reduced and further improvement can be expected in the future. Thirty-nine remained dependent on bifocals; and in 14, fus...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)78113-9
更新日期:1978-06-01 00:00:00
abstract::The technique of keratoprosthesis was used in 21 cases of severe and intractable forms of keratopathy during the past 3 1/2 years. The results in terms of visual acuity were satisfactory in more than half the cases. Significant problems that occurred after this procedure included the diagnosis and management of glauc...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(79)90465-3
更新日期:1979-08-01 00:00:00
abstract:PURPOSE:To determine the repeatability of automated retinal and choroidal thickness measurements with swept-source optical coherence tomography (SS OCT) and the frequency and type of scan artifacts. DESIGN:Prospective evaluation of new diagnostic technology. METHODS:Thirty healthy subjects were recruited prospectivel...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2014.02.008
更新日期:2014-05-01 00:00:00
abstract::Of 42 patients studied who had fundus flavimaculatus and Stargardt's disease, most had reduced visual acuity due to an atrophic macular lesion. Family histories were consistent with autosomal-recessive inheritance. In some young patients, the yellow-white flecks developed with time, while in some older patients the fl...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(76)90539-0
更新日期:1976-10-01 00:00:00
abstract::Upshoot and downshoot of the adducted eye in Duane's retraction syndrome is thought to be caused by a bridle effect of the co-contracting horizontal recti muscles. A recession of both of these muscles transposes their insertions posteriorly in relation to the center of rotation of the globe, which reduces the bridle e...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)71796-9
更新日期:1992-09-15 00:00:00
abstract:PURPOSE:To evaluate the anatomical and visual outcome in macular hole patients who underwent surgery with infracyanine green-assisted internal limiting membrane peeling. DESIGN:A prospective case series with 51 consecutive eyes of 49 patients with idiopathic, iatrogenic, or traumatic Stage 2, 3, or 4 macular holes. M...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(03)00543-9
更新日期:2003-11-01 00:00:00
abstract::Thirty-six patients who had clinically progressive Graves' dysthyroid orbitopathy were treated with supervoltage orbital radiotherapy. Twenty-three of the patients had discontinued the use of orally administered prednisone after developing intolerable side effects. Medical contraindications prevented seven patients fr...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)76158-6
更新日期:1992-04-15 00:00:00