Macrophages and dendritic cells: what is the difference?

abstract：BACKGROUND:The prevalence of cardiovascular disease (CVD) and inflammation is high in patients with end-stage renal disease (ESRD). Adiponectin is an adipocytokine that may have significant anti-inflammatory and anti-atherosclerotic effects. Low adiponectin levels have previously been found in patients with high risk f...

journal_title：Kidney international

authors： Stenvinkel P,Marchlewska A,Pecoits-Filho R,Heimbürger O,Zhang Z,Hoff C,Holmes C,Axelsson J,Arvidsson S,Schalling M,Barany P,Lindholm B,Nordfors L

更新日期：2004-01-01 00:00:00

abstract：:Diabetes mellitus is associated with natriuresis, whereas estrogen has been shown to be renoprotective in diabetic nephropathy and may independently regulate renal sodium reabsorption. The aim of this study was to determine the effects of 17-beta estradiol (E(2)) replacement to diabetic, ovariectomized (OVX) female ra...

journal_title：Kidney international

authors： Riazi S,Maric C,Ecelbarger CA

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Tacrolimus is a relatively new calcineurin inhibitor that has been increasingly used in transplant medicine. The objective of the current work is to report our preliminary experience with tacrolimus in the treatment of diffuse proliferative glomerulonephritis in systemic lupus erythematosus (SLE). METHODS:N...

journal_title：Kidney international

authors： Mok CC,Tong KH,To CH,Siu YP,Au TC

更新日期：2005-08-01 00:00:00

abstract：:We evaluated the effects of the bisphosphonate pamidronate on bone histomorphometry, structure and strength in male rats with uninephrectomy or with chronic renal disease induced by 5/6 nephrectomy. In rats with chronic renal disease the plasma urea, phosphate and parathyroid hormone levels were significantly increase...

journal_title：Kidney international

authors： Jokihaara J,Pörsti IH,Kööbi P,Jolma PM,Mustonen JT,Saha HH,Sievänen H,Kannus P,Iwaniec UT,Turner RT,Järvinen TL

更新日期：2008-08-01 00:00:00

abstract：:In order to study the effects of acute ureteral obstruction on glomerular hemodynamics, glomerular hydrostatic capillary pressure (PG), pressure in the first-order peritubular capillaries (EAP), and intratubular pressure (PT) were directly measured in superficial nephrons on Munich-Wistar rats by micropuncture with a ...

journal_title：Kidney international

authors： Dal Canton A,Stanziale R,Corradi A,Andreucci VE,Migone L

更新日期：1977-12-01 00:00:00

abstract：:We have previously shown that the activity of the Na-HCO3 cotransporter is stimulated by protein kinase C (PKC) activation, but the mechanism responsible for this effect is not clear. We have shown that cultured proximal tubule cells of the rabbit have DIDS-sensitive Na-HCO3 cotransporter activity as assessed by HCO3-...

journal_title：Kidney international

authors： Ruiz OS,Wang LJ,Qiu YY,Kear F,Bernardo A,Arruda JA

更新日期：1996-03-01 00:00:00

abstract：:Monocyte and macrophage markers are among the most highly overexpressed genes in cpk mouse kidneys with severely progressive renal cystic disease. We show here that one of these markers, CD14, is abnormally transcribed, activated and shed in cystic kidneys. However, these abnormalities were not associated with an incr...

journal_title：Kidney international

authors： Zhou J,Ouyang X,Cui X,Schoeb TR,Smythies LE,Johnson MR,Guay-Woodford LM,Chapman AB,Mrug M

更新日期：2010-09-01 00:00:00

abstract：:Because of high risk of cardiovascular disease, patients with chronic kidney disease may benefit from cholesterol-lowering therapy beyond statins. A cost-effectiveness analysis of adding ezetimibe to high-dose statins for primary cardiovascular disease prevention in patients with non-dialysis-dependent chronic kidney ...

journal_title：Kidney international

authors： Walther CP,Erickson KF

更新日期：2019-07-01 00:00:00

abstract：:Recent linkage analyses of nondiabetic African-American patients with focal segmental glomerulosclerosis (FSGS) have identified MYH9, encoding nonmuscle myosin heavy chain IIA (NMMHC-IIA), as a gene having a critical role in this disease. Abnormalities of the MYH9 locus also underlie rare autosomal dominant diseases s...

journal_title：Kidney international

authors： Sekine T,Konno M,Sasaki S,Moritani S,Miura T,Wong WS,Nishio H,Nishiguchi T,Ohuchi MY,Tsuchiya S,Matsuyama T,Kanegane H,Ida K,Miura K,Harita Y,Hattori M,Horita S,Igarashi T,Saito H,Kunishima S

更新日期：2010-07-01 00:00:00

abstract：:To test the contribution of bicarbonate (Bi) to hemodynamic stability during hemodialysis (HD), we compared the effects of ultrafiltration dialysis with bicarbonate and with acetate under conditions of high-sodium (141 mEq/liter) and low-sodium (130 mEq/liter) dialysate concentrations in 12 stable HD patients. Group 1...

journal_title：Kidney international

authors： Velez RL,Woodard TD,Henrich WL

更新日期：1984-07-01 00:00:00

abstract：BACKGROUND:A need exists for a therapy that lowers parathyroid hormone (PTH) without increasing calcium x phosphorus in patients with secondary hyperparathyroidism. The calcimimetic AMG 073 increases the sensitivity of the parathyroid calcium-sensing receptor to extracellular calcium, thereby reducing PTH secretion. Co...

journal_title：Kidney international

authors： Lindberg JS,Moe SM,Goodman WG,Coburn JW,Sprague SM,Liu W,Blaisdell PW,Brenner RM,Turner SA,Martin KJ

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Endothelium-derived nitric oxide and reactive oxygen species (ROS) have been proposed to regulate vascular tone by complex mechanisms, including the modulation of ion channel function. In endothelial function itself, activation of Ca2+-activated K+ channels (KCa) plays a crucial role by inducing hyperpolariz...

journal_title：Kidney international

authors： Brakemeier S,Eichler I,Knorr A,Fassheber T,Köhler R,Hoyer J

更新日期：2003-07-01 00:00:00

abstract：:Factor H is a regulator of the alternative pathway of complement, and genetic studies have shown that patients with mutations in factor H are at increased risk for several types of renal disease. Pathogenic activation of the alternative pathway in acquired diseases, such as ischemic acute kidney injury, suggests that ...

journal_title：Kidney international

authors： Renner B,Ferreira VP,Cortes C,Goldberg R,Ljubanovic D,Pangburn MK,Pickering MC,Tomlinson S,Holland-Neidermyer A,Strassheim D,Holers VM,Thurman JM

更新日期：2011-07-01 00:00:00

abstract：:One of the challenges of treating patients with glomerulonephritis is to accurately assess disease activity. As renal biopsies are routinely stained for deposits of C3 activation fragments and glomerular C3 deposits are found in most forms of glomerulonephritis, we sought to determine whether a relatively noninvasive ...

journal_title：Kidney international

authors： Sargsyan SA,Serkova NJ,Renner B,Hasebroock KM,Larsen B,Stoldt C,McFann K,Pickering MC,Thurman JM

更新日期：2012-01-01 00:00:00

abstract：:We report the stepwise application of the RIFLE classification in 155,624 admissions in the UK Intensive Care National Audit & Research Centre Case Mix Programme database. The assumptions required to define RIFLE and their relationship with renal replacement therapy (RRT) and ICU mortality were assessed. Previous repo...

journal_title：Kidney international

authors： Harris SK,Lewington AJ,Harrison DA,Rowan KM

更新日期：2015-08-01 00:00:00

abstract：:Plasma newly-synthesized cholesteryl ester transfer (NCET) rate and concentrations of lipids, lipoproteins and apolipoproteins A1 and B were measured in chronic renal failure patients (dialysis independent and dialysis dependent), patients with a functioning renal transplant and in healthy control subjects with compar...

journal_title：Kidney international

authors： Corboy J,Sutherland WH,Walker RJ,Robertson MC,Cox CM

更新日期：1994-10-01 00:00:00

abstract：:Hemodialysis has a profound effect on fluid balance. Since fluid is initially withdrawn from the intravascular compartment, blood volume will decrease rapidly. A fluid shift (refill) from the overhydrated interstitium towards the intravascular compartment counteracts hypovolemia. Underestimation of postdialytic dry we...

journal_title：Kidney international

authors： de Vries JP,Kouw PM,van der Meer NJ,Olthof CG,Oe LP,Donker AJ,de Vries PM

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND:Decreased red blood cell survival contributes to the anemia of chronic renal failure patients. Because patients on chronic dialysis therapy are frequently exposed to excessive complement activation, we investigated the susceptibility of this patient population to erythrocyte C5b-9 deposition, complement-medi...

journal_title：Kidney international

authors： Himmelfarb J,McMonagle E,Holbrook D,Hakim R

更新日期：1999-02-01 00:00:00

abstract：:Gene expression differs substantially among individual cells of the same type. We speculate that genes that are expressed in all but a portion of cells of a given cell type would be likely essential and required for either the cell survival (housekeeping) or for the cell type's unique structure and function, enabling ...

journal_title：Kidney international

authors： Lu Y,Ye Y,Bao W,Yang Q,Wang J,Liu Z,Shi S

更新日期：2017-11-01 00:00:00

abstract：:Hyperinsulinemia can contribute to hypertension through effects on sodium transport. To test whether the stimulatory effect of insulin on renal proximal tubule sodium transport is preserved in insulin resistance, we compared the effects of insulin on abdominal adipocytes and proximal tubules in rats and humans. Insuli...

journal_title：Kidney international

authors： Nakamura M,Yamazaki O,Shirai A,Horita S,Satoh N,Suzuki M,Hamasaki Y,Noiri E,Kume H,Enomoto Y,Homma Y,Seki G

更新日期：2015-03-01 00:00:00

abstract：UNLABELLED:Hereditary systemic amyloidosis associated with a new apolipoprotein AII stop codon mutation Stop78Arg. BACKGROUND:Mutations in the gene for apolipoprotein AII (apoAII) have recently been found to cause hereditary renal amyloidosis. In each case amyloid deposition has been associated with a peptide extensio...

journal_title：Kidney international

authors： Yazaki M,Liepnieks JJ,Barats MS,Cohen AH,Benson MD

更新日期：2003-07-01 00:00:00

abstract：:Albumin is an acceptor of lysophosphatidylcholine (LPC), product of the lecithin:cholesterol acyl transferase (LCAT) reaction, and it has been suggested that low LCAT activity and reduced cholesterol esterification rate in patients with the nephrotic syndrome may be linked to depletion of albumin. Effects of low plasm...

journal_title：Kidney international

authors： Joles JA,Willekes-Koolschijn N,Scheek LM,Koomans HA,Rabelink TJ,van Tol A

更新日期：1994-07-01 00:00:00

abstract：:Myeloproliferative neoplasms are clonal hematopoietic stem cell disorders that can produce an undefined glomerulopathy. To better characterize the glomerular disease associated with myeloproliferative neoplasms, we evaluated features of 11 patients with myeloproliferative neoplasm-related glomerulopathy that included ...

journal_title：Kidney international

authors： Said SM,Leung N,Sethi S,Cornell LD,Fidler ME,Grande JP,Herrmann S,Tefferi A,D'Agati VD,Nasr SH

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Glucose degradation products (GDPs) are cytotoxic in vitro and potentially toxic in vivo during peritoneal dialysis (PD). We are presenting the results of a two-year randomized clinical trial of a new PD fluid, produced in a two-compartment bag and designed to minimize heat-induced glucose degradation while ...

journal_title：Kidney international

authors： Rippe B,Simonsen O,Heimbürger O,Christensson A,Haraldsson B,Stelin G,Weiss L,Nielsen FD,Bro S,Friedberg M,Wieslander A

更新日期：2001-01-01 00:00:00

abstract：:Fibroblast growth factor-23 (FGF23), a regulator of mineral metabolism, has been linked to cardiovascular disease in chronic kidney disease. As community-based data of the longitudinal association between FGF23 and cardiovascular events are lacking, we investigated a possible relationship in 727 men of the Uppsala Lon...

journal_title：Kidney international

authors： Ärnlöv J,Carlsson AC,Sundström J,Ingelsson E,Larsson A,Lind L,Larsson TE

更新日期：2013-01-01 00:00:00

abstract：:The purpose of these studies was to clarify the basis of the relationship between the urine bicarbonate concentration and the urine minus blood PCO2 difference in alkaline urine (U-B PCO2) and hence shed light on factors that influence hydrogen ion secretion in the collecting duct in vivo. The U-B PCO2 was used to mon...

journal_title：Kidney international

authors： Tam SC,Goldstein MB,Stinebaugh BJ,Chen CB,Gougoux A,Halperin ML

更新日期：1981-11-01 00:00:00

abstract：:Vitamin D analogs may slow the progression of chronic kidney disease. Tan et al. report that paricalcitol has additive effects with an angiotensin-converting enzyme inhibitor (ACEI) in suppressing extracellular matrix expression, interstitial inflammation, and myofibroblast activation in obstructive nephropathy. Paric...

journal_title：Kidney international

authors： Li M,Batuman V

更新日期：2009-12-01 00:00:00

abstract：:This study examined the utility of interleukin-10 (IL-10), a cytokine with potent anti-macrophage and anti-Th1 activity, in the treatment of experimental anti-glomerular basement membrane (GBM) nephritis in the rat. Accelerated anti-GBM disease was induced in Sprague-Dawley rats by immunization with rabbit IgG, follow...

journal_title：Kidney international

authors： Chadban SJ,Tesch GH,Lan HY,Atkins RC,Nikolic-Paterson DJ

更新日期：1997-06-01 00:00:00

abstract：:Hypertriglyceridemia in nephrotic (NS) and Nagase analbuminemic rats (Analb) results from reduced triglyceride clearance. NS and Analb have reduced or absent albumin, reduced plasma oncotic pressure (pi), but Analb lack proteinuria. The heparin releasable lipoprotein lipase (LpL) pool in both models is greatly reduced...

journal_title：Kidney international

authors： Shearer GC,Kaysen GA

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:Our preliminary studies indicate that chronic caffeine consumption has adverse renal effects in nephropathy associated with high blood pressure and insulin resistance. The purpose of this study was to investigate the effects of early (beginning at 8 weeks of age) and long-term (30 weeks) caffeine treatment (...

journal_title：Kidney international

authors： Tofovic SP,Kost CK Jr,Jackson EK,Bastacky SI

更新日期：2002-04-01 00:00:00