Abstract:
:Maturation of T4 can proceed in the presence of 5-methyltryptophan or puromycin. Puromycin inhibits phage protein synthesis within a few seconds, thus limiting the amount of phage precursor material available for maturation. After the arrest of protein synthesis, maturation continues unabated until the limiting protein precursor is depleted. At least one protein, the tail fiber protein, is depleted. Phage protein maturable in the presence of puromycin appears about 5 minutes before maturation begins. The level of the maturable material reaches a maximum at the beginning of maturation. This level is taken as a measure of the size of the pool of complete sets of maturable phage protein. The bulk precursor protein begins to accumulate 3 minutes earlier than serum blocking proteins (SBP) and forms a pool about twice as large as the pool of SBP.
journal_name
Virologyjournal_title
Virologyauthors
Piechowski MM,Susman Mdoi
10.1016/0042-6822(66)90050-xsubject
Has Abstractpub_date
1966-03-01 00:00:00pages
386-95issue
3eissn
0042-6822issn
1096-0341pii
0042-6822(66)90050-Xjournal_volume
28pub_type
杂志文章相关文献
VIROLOGY文献大全abstract::Influenza A virus, a respiratory pathogen manipulates various host cellular processes to establish a successful infection in a host. We had reported earlier the interaction of influenza A virus nucleoprotein with host glycolytic enzymes; alpha enolase and pyruvate kinase in A549 cells. Matrix protein (M1), another mul...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2020.07.019
更新日期:2020-10-01 00:00:00
abstract::In response to oncogenic insults, normal human cells execute a defense response that culminates in cellular suicide, apoptosis. Normal human diploid fibroblasts expressing the human papillomavirus type 16 (HPV-16) E7 oncoprotein are predisposed to apoptosis when they are deprived of growth factors. Even though a domin...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2003.11.008
更新日期:2004-02-05 00:00:00
abstract::Coxsackievirus B4 (CBV4), a member of the Picornavirus genus, has long been implicated in the development of insulin-dependent diabetes mellitus (IDDM), by viral-induced pancreatic cell damage. Although the pancreotropic nature of this virus is well documented, the early stages of CBV4 viral infection that involve the...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2004.04.051
更新日期:2004-08-15 00:00:00
abstract::The lung-derived dendritic cell (LDC) recruitment following intranasal (i.n.) vaccination of different poxviral vector-based vaccines/adjuvants were evaluated to decipher how these factors influenced CD8(+) T cell avidity. Compared to the standard i.n. recombinant fowlpox virus (FPV)-HIV vaccination, the FPV-HIV IL-13...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2014.09.004
更新日期:2014-11-01 00:00:00
abstract::The 121,752-bp genome sequence of bacteriophage T5 was determined; the linear, double-stranded DNA is nicked in one of the strands and has large direct terminal repeats of 10,139 bp (8.3%) at both ends. The genome structure is consistently arranged according to its lytic life cycle. Of the 168 potential open reading f...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2004.10.049
更新日期:2005-02-05 00:00:00
abstract::A chloroplast-localized papaya methionine sulfoxide reductase B1 (PaMsrB1) interacting with Papaya ringspot virus (PRSV) NIa-Pro was identified using a Sos recruitment two-hybrid system (SRS). SRS analysis of several deletion mutants of PRSV NIa-Pro and PaMsrB1 demonstrated that the C-terminal (residues 133-239) fragm...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2012.09.007
更新日期:2012-12-05 00:00:00
abstract::The subgroup C human adenovirus L4 33-kDa protein is a nuclear phosphoprotein that plays a direct, but dispensable, role in virion assembly. The r-strand open reading frame (ORF) for this protein lies opposite to the 5' end of the l-strand E2 early (E2E) transcription units. To facilitate studies of regulation of E2E ...
journal_title:Virology
pub_type: 杂志文章
doi:10.1006/viro.2001.1130
更新日期:2001-10-25 00:00:00
abstract::We have examined the synthesis of the T protein of the human polyomavirus, JCV, during productive infection in primary cultures of human fetal glial and kidney cells. Immunoprecipitation of protein extracts from virus infected cells revealed that the JCV large T protein from both the prototype Mad and HEK adapted stra...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(86)90418-6
更新日期:1986-01-15 00:00:00
abstract::Sulfolobus turreted icosahedral virus (STIV) infects Sulfolobus species found in the hot springs of Yellowstone National Park. Its 37 open reading frames (ORFs) generally lack sequence similarity to other genes. One exception, however, is ORF B116. While its function is unknown, orthologs are found in three additional...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2007.01.027
更新日期:2007-07-05 00:00:00
abstract::The P150 and P90 replicase proteins of rubella virus (RUBV), a plus-strand RNA Togavirus, produce a unique cytoplasmic fiber network resembling microtubules. Pharmacological and mutagenic approaches were used to determine if these fibers functioned in virus replication. The pharmacological approach revealed that micro...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2010.07.025
更新日期:2010-10-25 00:00:00
abstract::Attachment of human adenoviruses (Ads) to host cells is mediated by the interaction of the fiber protein of the capsid with specific cell-surface molecules. For one of the species B adenoviruses, Ad3, the mechanism of binding to cells remains to be defined. Several previous reports have proposed CD46, CD80 or CD86 as ...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2009.07.010
更新日期:2009-09-30 00:00:00
abstract::Mouse hybridomas which produce monoclonal antibodies to the Autographa californica nuclear polyhedrosis virus (AcNPV) have been prepared and the protein to which each is directed has been determined. The antibody produced by clones 3F3 and 5E9 specifically bound polyhedron protein of MW 32,000 when used in immunoadsor...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(82)90241-0
更新日期:1982-10-30 00:00:00
abstract::In a plantar cyst composed of the wall of the squamous cell layer and the horny inner substance in the lower dermis, we found characteristic pathological changes, such as cytoplasmic eosinophilic inclusions and vacuolated structure, and, immunohistochemically, the papillomavirus capsid antigen. The human papillomaviru...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(92)91254-r
更新日期:1992-09-01 00:00:00
abstract::An H5N6 highly pathogenic avian influenza virus (HPAIV) outbreak occurred in poultry in Japan during January 2018, and H5N6 HPAIVs killed several wild birds in 3 prefectures during Winter 2017-2018. Time-measured phylogenetic analyses demonstrated that the Hemagglutinin (HA) and internal genes of these isolates were g...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2019.04.011
更新日期:2019-07-01 00:00:00
abstract::The gene encoding the VP8* trypsin-cleavage product of the VP4 protein of porcine rotavirus strain A34 was sequenced, and the predicted amino acid (aa) sequence was compared to the homologous region of all known P genotypes. The aa sequence of the VP8* of strain A34 shared low identity, ranging from 39% (bovine strain...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/s0042-6822(03)00534-8
更新日期:2003-10-25 00:00:00
abstract::An immunodominant region of VP3, one of the two structural proteins of infectious bursal disease virus (IBDV strain 002-73), has been mapped by restriction site-specific deletion analysis and subcloning in Escherichia coli, followed by immunoblot analysis of the synthesized products. The epitope located within 58 amin...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(91)90457-m
更新日期:1991-10-01 00:00:00
abstract::Cell-mediated immunity plays a key role in the regression of papillomavirus-induced warts and intra-epithelial lesions but the target antigens that induce this response are not clear. Canine oral papillomavirus (COPV) infection of the oral cavity in dogs is a well-characterized model of mucosal papillomavirus infectio...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2006.07.032
更新日期:2006-12-05 00:00:00
abstract::IFN responses control acute HSV infection, but their role in regulating HSV latency is poorly understood. To address this we used mice lacking IFN signaling specifically in neural tissues. These mice supported a higher acute viral load in nervous tissue and delayed establishment of latency. While latent HSV-1 genome c...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2016.06.016
更新日期:2016-10-01 00:00:00
abstract::The 130-kDa bovine herpesvirus-1 (BHV-1) glycoprotein GVP 6 was found to cross-react immunologically with the herpes simplex glycoprotein gB. Antibodies in polyclonal serum against gB immunoprecipitated GVP 6 and its cleavage products from a lysate of BHV-1-infected cells. Conversely, polyclonal serum against GVP 6 pr...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(88)90525-9
更新日期:1988-10-01 00:00:00
abstract::Although a live attenuated HIV vaccine is not currently considered for safety reasons, a strategy inducing both T cells and neutralizing antibodies to native assembled HIV-1 particles expressed by a replicating virus might mimic the advantageous characteristics of live attenuated vaccine. To this aim, we generated a l...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2009.02.047
更新日期:2009-05-25 00:00:00
abstract::The complete genome sequence of the Liaoning isolate of the Antheraea pernyi multinucleocapsid nucleopolyhedrovirus (AnpeMNPV) was determined. The viral genome size is 126,246 bp, relatively GC-rich (53.5% G+C), with 145 predicted open reading frames (ORFs) of more than 50 amino acids, accounting for more than 97% of ...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2007.04.027
更新日期:2007-09-30 00:00:00
abstract::Purified preparations of the Helminthosporium victoriae 190S (Hv190S) virus contain two sedimenting components that differ in capsid structure. The slower sedimenting component (190S-1) contained p88 and p83 as the major capsid proteins; the faster component (190S-2) contained p88 and p78. Previous peptide-mapping stu...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(92)90520-y
更新日期:1992-06-01 00:00:00
abstract::The reticuloendotheliosis virus (REV) group of retroviruses and type D simian retroviruses (SRV) belong to the same receptor interference group. The cellular receptor for these viruses has not yet been identified. In order to study the distribution of the receptor and to identify a receptor negative cell line, vector ...
journal_title:Virology
pub_type: 杂志文章
doi:10.1006/viro.1994.1651
更新日期:1994-11-15 00:00:00
abstract::The adenovirus E1A 243R oncoprotein encodes a potent transcription-repression function within the N-terminal 80 amino acids. Our proposed model of E1A repression predicts that E1A interacts with important cellular proteins on chromatin. Consistent with this idea, we report here that E1A proteins from in vivo formaldeh...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2007.10.021
更新日期:2008-02-05 00:00:00
abstract::Human immunodeficiency virus type 1 (HIV-1) Tat transcriptionally activates expression from a number of viral and cellular promoters. Recent studies demonstrate the ability of Tat to differentially modulate cellular responses to apoptotic signaling. The antiapoptotic effects of Tat appear to correlate with increased e...
journal_title:Virology
pub_type: 杂志文章
doi:10.1006/viro.1999.9688
更新日期:1999-05-10 00:00:00
abstract::In our in vitro model for HPV16-mediated transformation, HPV16-immortalized human keratinocytes (HKc/HPV16) give rise to differentiation resistant, premalignant cells (HKc/DR). HKc/DR, but not HKc/HPV16, are resistant to growth inhibition by transforming growth factor beta (TGF-β), due to a partial loss of TGF-β recep...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2013.08.034
更新日期:2013-12-01 00:00:00
abstract::The genome of peanut clump pecluvirus (PCV) consists of two messenger RNA components which contain, respectively, three and five open reading frames (ORFs). Inoculation of transcripts from full-length cDNA clones derived from the PCV RNAs showed that RNA-1 is able to replicate in the absence of RNA-2 in protoplasts, b...
journal_title:Virology
pub_type: 杂志文章
doi:10.1006/viro.1998.9287
更新日期:1998-09-01 00:00:00
abstract::The large (L) proteins of non-segmented negative stranded (NNS) RNA viruses contain the core RNA dependent RNA polymerase activity for RNA replication and transcription as well as the activities for polyadenylating and capping the mRNA transcripts and for methylating the cap structures. There is currently no structura...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2008.08.041
更新日期:2008-12-05 00:00:00
abstract::Two minor proteins with molecular masses of 8.5 and 15.5 kDa were identified in feline calicivirus (FCV) virions. Direct sequence analysis showed that the N-terminal sequence of the 8.5-kDa protein was identical to that of the predicted protein encoded by open reading frame 3 (ORF3) of the FCV genome. The N-terminal s...
journal_title:Virology
pub_type: 杂志文章
doi:10.1006/viro.2000.0579
更新日期:2000-11-10 00:00:00
abstract::Corn lethal necrosis (CLN) is caused by the synergistic interaction between maize chlorotic mottle machlomovirus (MCMV) and any potyvirus which infects cereals. Interactions between MCMV and wheat streak mosaic rymovirus (WSMV) in N28Ht corn produced MCMV concentrations that averaged 3.3- to 11.2-fold higher in doubly...
journal_title:Virology
pub_type: 杂志文章
doi:10.1006/viro.1997.8989
更新日期:1998-03-01 00:00:00