Alteration of amino acids in cerebrospinal fluid from patients with Parkinson's disease and spinocerebellar degeneration.

abstract：:Sympathetic denervation of the brain vessels was performed uni- or bilaterally in 13 adult rabbits, and cortical cold lesions were induced bilaterally 10-18 days afterwards. After a further 4-35 days the vascular and morphological changes in the lesion areas were studied histologically and with angiography. No differe...

journal_title：Acta neurologica Scandinavica

authors： West KA,Hassler O

更新日期：1976-09-01 00:00:00

abstract：OBJECTIVES:Optic neuritis (ON) often precedes multiple sclerosis (MS). MS is associated with a significant socioeconomic burden. However, the burden of ON with and without MS before and after its diagnosis has never been calculated. METHODS:Using complete national records from the Danish National Patient Registry (199...

journal_title：Acta neurologica Scandinavica

authors： Jennum P,Frederiksen JL,Wanscher B,Kjellberg J

更新日期：2013-04-01 00:00:00

abstract：AIMS:To conduct a psychometric analysis to determine the adequacy of instruments that measure cognition in Alzheimer's disease trials. BACKGROUND:Both the Alzheimer's Disease Assessment Scale - Cognition (ADAS-Cog) and the Neuropsychological Test Battery (NTB) are validated outcome measures for clinical trials in Alzh...

journal_title：Acta neurologica Scandinavica

authors： Karin A,Hannesdottir K,Jaeger J,Annas P,Segerdahl M,Karlsson P,Sjögren N,von Rosen T,Miller F

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVES:We studied the in vitro production of variably MS-related cytokines from Sardinian MS and healthy donors bearing the two "Sardinian" MS-associated HLA-DR alleles: DR3 and DR4, with the purpose to evidentiate possible differences in their immune response. MATERIALS AND METHODS:ELISA were used for detection o...

journal_title：Acta neurologica Scandinavica

authors： Sotgiu S,Serra C,Marrosu MG,Dolei A,Pugliatti M,Murgia B,Aiello I,Rosati G

更新日期：1998-11-01 00:00:00

abstract：:Alterations in nervous system functioning following acute and chronic ethanol exposure have been studied in a great number of experimental investigations. Results from many of these investigations can be difficult to interpret, particularly since a variety of techniques and exposure models are employed. This review em...

journal_title：Acta neurologica Scandinavica

authors： Melgaard B

更新日期：1983-03-01 00:00:00

abstract：:We present clinical and virological data on 9 patients, 7 women and 2 men aged 31-56 years, with recurrent aseptic meningitis (Mollaret's meningitis). Polymerase chain reaction detected Herpes simplex virus type 2 DNA in cerebrospinal fluid samples from all patients collected during their latest attacks of meningitis....

journal_title：Acta neurologica Scandinavica

authors： Jensenius M,Myrvang B,Størvold G,Bucher A,Hellum KB,Bruu AL

更新日期：1998-09-01 00:00:00

abstract：OBJECTIVES:To assess predictors of headache in patients who had sustained a head injury 22 years earlier. MATERIALS AND METHODS:A questionnaire about headache was sent to 361 subjects hospitalized for head injury in 1974-1975. RESULTS:A total of 249 patients (69%) responded to the questionnaire. The prevalence of hea...

journal_title：Acta neurologica Scandinavica

authors： Nestvold K,Lundar T,Mowinckel P,Stavem K

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVE:To evaluate the clinical course of patients with myasthenia gravis (MG) up to 3 months after double filtration plasmapheresis (DFP). MATERIAL AND METHODS:We recorded the MG score and measured the level of acetylcholine receptor antibody (AchRAb) at baseline and day 1 (D1), week 1 (W1), 1 month (M1), 2 (M2) a...

journal_title：Acta neurologica Scandinavica

authors： Yeh JH,Chen WH,Chiu HC

更新日期：2003-09-01 00:00:00

abstract：OBJECTIVES:Biomarkers with the potential for longitudinal measurements are needed in multiple sclerosis (MS). Urine is easy to collect, and repeated sampling is possible. METHODS:39 paired CSF and urine samples were taken. Oligoclonal bands (OCBs) were measured in CSF. Kappa and lambda free light chain (FLC), neopteri...

journal_title：Acta neurologica Scandinavica

authors： Dobson R,Topping J,Davis A,Thompson E,Giovannoni G

更新日期：2013-11-01 00:00:00

abstract：:The clinical features in 268 patients with diffuse cerebral atrophy of initially unknown origin have been analysed. Pneumoencephalography showed supratentorial ventricular atrophy in 87 per cent (cortical in 71 per cent), and brain stem and/or cerebellar atrophy in 17 per cent of the patients. Epileptic seizures, dizz...

journal_title：Acta neurologica Scandinavica

authors： Iivanainen M

更新日期：1975-04-01 00:00:00

abstract：:The possibility of disturbed dopamine and serotonin metabolism in senile dementia of Alzheimer type was studied. The basal concentrations of homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA) in cerebrospinal fluid (CSF) were studied in 28 patients with senile dementia of Alzheimer type and in 13 controls...

journal_title：Acta neurologica Scandinavica

authors： Soininen H,MacDonald E,Rekonen M,Riekkinen PJ

更新日期：1981-08-01 00:00:00

abstract：:A total of 43 patients with multiple sclerosis (MS) consecutively admitted to the Multiple Sclerosis Rehabilitation Hospital in Haslev completed a Danish version of the Laman & Lankhorst Questionnaire (LLQ) on quality of life (qol), and the Beck Depression Inventory (BDI). Twenty-one of the 43 pts completed the questi...

journal_title：Acta neurologica Scandinavica

authors： Jønsson A,Dock J,Ravnborg MH

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:Far from being uniform, Huntington's disease (HD)'s phenotype encompasses a large variety of motor and non-motor symptoms which occur in various combinations in individual patients. AIM:To describe an unusual association between restless legs syndrome (RLS) and HD. METHODS AND RESULTS:We report a patient w...

journal_title：Acta neurologica Scandinavica

authors： Savva E,Schnorf H,Burkhard PR

更新日期：2009-04-01 00:00:00

abstract：:The effects of bromocriptine in patients with Parkinson's disease manifesting various problems in levodopa therapy were tested in a double-blind manner with the collaboration of 59 institutions. The slow and low principle was in part adopted. Either bromocriptine or placebo was added to levodopa. Twenty-nine % of the ...

journal_title：Acta neurologica Scandinavica

authors： Toyokura Y,Mizuno Y,Kase M,Sobue I,Kuroiwa Y,Narabayashi H,Uono M,Nakanishi T,Kameyama M,Ito H

更新日期：1985-08-01 00:00:00

abstract：OBJECTIVES:It was shown previously that low-Mg2+-induced epileptiform activity in rat entorhinal cortex slices changes with time from a pattern of serial seizure-like events (SLEs) to a state of continuously recurring epileptiform activity. Valproic acid blocked the early SLEs but not the late activity. It was proposed...

journal_title：Acta neurologica Scandinavica

authors： Dreier JP,Zhang CL,Heinemann U

更新日期：1998-09-01 00:00:00

abstract：:The present communication is devoted to investigating the possibility that in myotonic dystrophy (MyD) a decreased ATP utilization by the membrane may produce modifications in glycoprotein structure and/or in the supramolecular arrangement of some membrane proteins. The study was carried out a) by determining the memb...

journal_title：Acta neurologica Scandinavica

authors： Sandrini G,Bottiroli G,Nappi G,Balduini C,Brovelli A

更新日期：1982-06-01 00:00:00

abstract：OBJECTIVES:Evaluate interim long-term tolerability, safety and efficacy of adjunctive perampanel, a novel α-amino-3-hydroxy-5-methyl-5-isoxazolepropionic acid (AMPA)-receptor antagonist, in patients with refractory partial-onset seizures. MATERIALS AND METHODS:Study 207, an open-label extension (OLE) study (ClinicalTr...

journal_title：Acta neurologica Scandinavica

authors： Rektor I,Krauss GL,Bar M,Biton V,Klapper JA,Vaiciene-Magistris N,Kuba R,Squillacote D,Gee M,Kumar D

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVES:We used an electrical conditioning stimulation followed by transcranial magnetic stimulation (TMS) to facilitate the occurrence of long latency potentials (LLPs) in order to study the relationship between primary motor evoked potentials (MEPs) and LLPs in the lower limbs. MATERIALS AND METHODS:The study gro...

journal_title：Acta neurologica Scandinavica

authors： Chen JT,Chen CC,Kao KP,Wu ZA,Liao KK

更新日期：1998-12-01 00:00:00

abstract：:This is the first epidemiological study of myasthenia gravis (MG) in the area of Belgrade. During the survey period (1983 1992), 124 incidental cases of MG were observed, producing an average annual incidence rate of 7.1 per million population (women, 8.3; men, 5.8). Age and sex specific incidence rates for females de...

journal_title：Acta neurologica Scandinavica

authors： Lavrnić D,Jarebinski M,Rakocević-Stojanović V,Stević Z,Lavrnić S,Pavlović S,Trikić R,Tripković I,Nesković V,Apostolski S

更新日期：1999-09-01 00:00:00

abstract：:The effect of a new peripherally acting muscle relaxant drug Dantrium, on spasticity tested on 11 hemiplegic patients. The effect was evaluated both with regular clinical examination and with electromyographic technique. The latter concerned a quantitative analysis of the patients' voluntary control of fine neuromuscu...

journal_title：Acta neurologica Scandinavica

authors： Jonsson B,Ladd H,Afzelius-Frisk I,Lindberg-Broman AM

更新日期：1975-05-01 00:00:00

abstract：:Twenty-four male patients, all homosexual except one, with asymptomatic HIV-infection were studied. The patients had no signs of opportunistic CNS-infections but 6 had been treated for syphilis. The patients were tested with auditory brainstem response (ABR) audiometry and with oculomotor tests (saccades and smooth pu...

journal_title：Acta neurologica Scandinavica

authors： Rosenhall U,Håkansson C,Löwhagen GB,Hanner P,Jonsson-Ehk B

更新日期：1989-02-01 00:00:00

abstract：OBJECTIVES:To investigate eventual differences between women and men with Parkinson's disease (PD) before and after surgery, with respect to clinical status, disability and health-related quality of life (HRQoL). MATERIAL AND METHODS:Twenty-four men and 14 women with PD received a total of 46 surgical procedures (pall...

journal_title：Acta neurologica Scandinavica

authors： Hariz GM,Lindberg M,Hariz MI,Bergenheim AT

更新日期：2003-07-01 00:00:00

abstract：OBJECTIVES:To compare intravenous phenytoin (PHT) and intravenous lacosamide (LCM) for treatment of status epilepticus after failure of the first and second drug. METHODS:We retrospectively identified patients from a large community hospital in northern Germany who had been diagnosed with SE between August 2008 and De...

journal_title：Acta neurologica Scandinavica

authors： Kellinghaus C,Berning S,Stögbauer F

更新日期：2014-05-01 00:00:00

abstract：:Alzheimer's disease (AD) and vascular dementia (VD) are the two most common causes of dementia. As yet, no definitive biological antemortem marker has been established for differential diagnosis of AD or VD. In this study, proteins of cerebrospinal fluid (CSF) from AD, VD and control patients were analyzed by two-dime...

journal_title：Acta neurologica Scandinavica

authors： Mattila KM,Pirttilä T,Blennow K,Wallin A,Viitanen M,Frey H

更新日期：1994-03-01 00:00:00

abstract：:The cerebral blood flow is low in primary polycythaemia, and it has been suggested that this is due to the increase in viscosity which accompanies the elevated haematocrit. In the present study cerebral blood flow has been measured by a non-invasive 133Xenon technique in six subjects with an elevated haematocrit secon...

journal_title：Acta neurologica Scandinavica

authors： Wade JP,du Boulay GH,Marshall J,Pearson TC,Russell RW,Shirley JA,Symon L,Wetherley-Mein G,Zilkha E

更新日期：1980-04-01 00:00:00

abstract：OBJECTIVE:To validate the diagnosis of idiopathic intracranial hypertension (IIH) from the Swedish National Patient Register (NPR) and investigate the incidence of IIH, as well as co-morbidities and medication use in a large Swedish population-based sample. METHODS:We searched the NPR to find all patients ≥18 years ol...

journal_title：Acta neurologica Scandinavica

authors： Sundholm A,Burkill S,Sveinsson O,Piehl F,Bahmanyar S,Nilsson Remahl AIM

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:To study the relationship between cerebral hemodynamics and clinical performance in normal pressure hydrocephalus (NPH), before and after surgery. MATERIAL AND METHODS:Ten patients were studied prospectively before and 3 months after shunt surgery by means of transcranial Doppler (TCD). Clinical performance ...

journal_title：Acta neurologica Scandinavica

authors： Bakker SL,Boon AJ,Wijnhoud AD,Dippel DW,Delwel EJ,Koudstaal PJ

更新日期：2002-09-01 00:00:00

abstract：:The prophylactic effect of a 5-HT uptake inhibitor, femoxetine, was compared with that of propranolol in a double-blind crossover study of 6-months duration. 29 patients commenced the experiment. 3 subjects withdrew because of side effects and 2 because the program was inconvenient for them. In the 24 patients who con...

journal_title：Acta neurologica Scandinavica

authors： Kangasniemi PJ,Nyrke T,Lang AH,Petersen E

更新日期：1983-10-01 00:00:00

abstract：INTRODUCTION:In patients with cervical root syndromes, the relation between clinical findings and EMG results, the value of the registration of the H-reflex latency of the flexor carpi radial muscle (HFCR) and the rate of recovery of EMG abnormalities following surgery are unclear. METHODS:In 68 patients with cervical...

journal_title：Acta neurologica Scandinavica

authors： van den Bent MJ,Oosting J,Laman DM,van Duijn H

更新日期：1995-10-01 00:00:00

abstract：OBJECTIVE:Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a severe autoimmune disorder with a mortality of 5%-7%, but few studies have focused on the predictors of death in this disease. In this study, we aim to investigate predictors and causes of death in patients with anti-NMDAR encephalitis. METHODS:In ...

journal_title：Acta neurologica Scandinavica

authors： Chi X,Wang W,Huang C,Wu M,Zhang L,Li J,Zhou D

更新日期：2017-10-01 00:00:00