Cerebral blood flow, haematocrit and viscosity in subjects with a high oxygen affinity haemoglobin variant.

Abstract:

:The cerebral blood flow is low in primary polycythaemia, and it has been suggested that this is due to the increase in viscosity which accompanies the elevated haematocrit. In the present study cerebral blood flow has been measured by a non-invasive 133Xenon technique in six subjects with an elevated haematocrit secondary to a haemoglobin variant with increased oxygen affinity. Flow was significantly higher than normal and 81% higher than in 11 subjects of comparable age, matched for haematocrit and viscosity, but without the haemoglobin variant. In patients with this unusual type of polycythaemia, cerebral blood flow is high despite the elevated blood viscosity and the implications of these results are discussed.

journal_name

Acta Neurol Scand

authors

Wade JP,du Boulay GH,Marshall J,Pearson TC,Russell RW,Shirley JA,Symon L,Wetherley-Mein G,Zilkha E

doi

10.1111/j.1600-0404.1980.tb01485.x

subject

Has Abstract

pub_date

1980-04-01 00:00:00

pages

210-5

issue

4

eissn

0001-6314

issn

1600-0404

journal_volume

61

pub_type

杂志文章
  • Management of urinary incontinence in children with myelomeningocele.

    abstract::Several forms of treatment of lower urinary tract functional disorders have been attempted in children with myelomeningocele (MMC). Intravesical electrical stimulation was attempted in 10 patients. Urinary control was achieved in one and in the remaining 9 either the bladder was resistant to stimulation or the childre...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1987.tb07888.x

    authors: Petersen T

    更新日期:1987-01-01 00:00:00

  • Quantitative SPECT cisternography in normal pressure hydrocephalus.

    abstract::Twenty-one patients with normal pressure hydrocephalus (NPH), 8 patients with various brain diseases with an element of hydrocephalus, and 7 patients with miscellaneous dementia disorders were investigated with quantitative radionuclide cisternography (RC) using single photon emission computerized tomography (SPECT). ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1994.tb02704.x

    authors: Larsson A,Arlig A,Bergh AC,Bilting M,Jacobsson L,Stephensen H,Wikkelsö C

    更新日期:1994-09-01 00:00:00

  • Efficacy of a soft hand brace and a wrist splint for carpal tunnel syndrome: a randomized controlled study.

    abstract:OBJECTIVE:To examine, in a randomized, controlled, single blinded trial, the efficacy of a soft hand brace and a wrist splint for carpal tunnel syndrome (CTS). METHODS:We randomized 120 patients with CTS into a group wearing the soft hand brace MANU and into another group wearing the wrist splint CAMP TIELLE at night ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1600-0404.2008.01072.x

    authors: De Angelis MV,Pierfelice F,Di Giovanni P,Staniscia T,Uncini A

    更新日期:2009-01-01 00:00:00

  • Cerebrospinal fluid investigations in multi-infarct dementia and senile dementia.

    abstract::Thirty-eight demented patients were clinically investigated and classified into a multi-infarct dementia (MID) and senile dementia (SD) group. Total protein, albumin, immunoglobulin G, agar gel electrophoretic protein and iso-electric focusing pattern were determined in CSF and serum as well as the lactate dehydrogena...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1981.tb04380.x

    authors: Wikkelsø C,Blomstrand C,Nordquist P

    更新日期:1981-07-01 00:00:00

  • Enzyme-linked immunosorbent assay for detection of antibodies to extractable muscle antigens in myasthenia gravis.

    abstract::A purified citric acid soluble extract from human skeletal muscle (AEMA) and a phosphate-buffered saline extract from rabbit muscle acetone powder (EMA) were used to coat polystyrene beads in an enzyme-linked immunosorbent assay (ELISA). From 54 patients with myasthenia gravis, positive results were observed in 14. Fi...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1986.tb04606.x

    authors: Viana VS,Bueno C,Marchiori PE,Oliveira RM,Assis JL,Scaff M,Cossermelli W

    更新日期:1986-06-01 00:00:00

  • Serum soluble interleukin-2 receptor levels in chronic progressive, stable and steroid-treated multiple sclerosis.

    abstract::Serum levels of the soluble interleukin-2 receptor (sIL-2R), an indicator of T cell activation, were significantly elevated in chronic progressive MS (CPMS) patients, clinically stable MS patients and in patients with other neurological diseases (OND) as compared to healthy controls. Levels of sIL-2R in steroid treate...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1991.tb04955.x

    authors: Bansil S,Troiano R,Cook SD,Rohowsky-Kochan C

    更新日期:1991-10-01 00:00:00

  • Clinical neurological findings among metal degreasers exposed to chlorinated solvents.

    abstract::Among industrial solvents in present use trichloroethylene belongs to those which have been the concern of most neurological and occupational investigations since the beginning of this century. Reports on a broad spectrum of neurotoxicity are however mostly based on case-studies and accidental circumstances. The objec...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1993.tb04101.x

    authors: Rasmussen K,Arlien-Søborg P,Sabroe S

    更新日期:1993-03-01 00:00:00

  • Psychological characteristics of patients with myotonic dystrophy type 1.

    abstract:OBJECTIVES:Myotonic dystrophy type 1 (DM1) is the most common adult-onset muscular dystrophy. It is associated with motor symptoms but patients also display non-motor symptoms such as particular personality traits. Studies have reported mixed results about personality characteristics which may be attributable to small ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.12356

    authors: Bertrand JA,Jean S,Laberge L,Gagnon C,Mathieu J,Gagnon JF,Richer L

    更新日期:2015-07-01 00:00:00

  • Computerized cognition assessment during acetylcholinesterase inhibitor treatment in Alzheimer's disease.

    abstract:OBJECTIVES:Alzheimer's disease assessment scale-cognitive subscale (ADAS-Cog) has become a standard clinical trials outcome for cognition, but has been recognized as deficient in areas including coverage of cognitive domains, sensitivity and standardization. Computerized test batteries may address some of these issues....

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.2009.01309.x

    authors: Wesnes K,Edgar C,Andreasen N,Annas P,Basun H,Lannfelt L,Zetterberg H,Blennow K,Minthon L

    更新日期:2010-10-01 00:00:00

  • Relation between angiographic cerebral vasospasm and regional CBF in patients with SAH.

    abstract::The relation between angiographically determined cerebral vasospasm following a subarachnoid hemorrhage and regional cerebral blood flow (CBF) was studied in 63 investigations of 45 patients. The CBF was measured using the intra-arterial 133-Xe clearance technique within one hour of angiography. A positive correlation...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1990.tb01598.x

    authors: Jakobsen M,Overgaard J,Marcussen E,Enevoldsen EM

    更新日期:1990-08-01 00:00:00

  • Motor compensation and recovery for reaching in stroke patients.

    abstract:OBJECTIVES:To examine the mechanisms of alternative strategies developed by stroke patients to compensate their motor impairment and their role in recovery. MATERIAL AND METHODS:The three-dimensional kinematics of the upper limb were quantified during unconstrained reaching movements in seven healthy individuals and i...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0404.2003.00021.x

    authors: Roby-Brami A,Feydy A,Combeaud M,Biryukova EV,Bussel B,Levin MF

    更新日期:2003-05-01 00:00:00

  • Cerebrospinal fluid nitrate levels in patients with Parkinson's disease.

    abstract::It has been suggested that nitric oxide could be implicated in the neuronal degeneration of substantia nigra compacta in patients with Parkinson's disease. Recently, it has been reported decreased CSF nitrate levels (oxidation product that provides an indirect estimation of nitric oxide) in Parkinson's disease patient...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1996.tb00186.x

    authors: Molina JA,Jiménez-Jiménez FJ,Navarro JA,Vargas C,Gómez P,Benito-León J,Ortí-Pareja M,Cisneros E,Arenas J

    更新日期:1996-02-01 00:00:00

  • Femoxetine - a new 5-HT uptake inhibitor - and propranolol in the prophylactic treatment of migraine.

    abstract::The prophylactic effect of a 5-HT uptake inhibitor, femoxetine, was compared with that of propranolol in a double-blind crossover study of 6-months duration. 29 patients commenced the experiment. 3 subjects withdrew because of side effects and 2 because the program was inconvenient for them. In the 24 patients who con...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1983.tb04836.x

    authors: Kangasniemi PJ,Nyrke T,Lang AH,Petersen E

    更新日期:1983-10-01 00:00:00

  • Bilateral mesial temporal lobe epilepsy: comparison of scalp EEG and hippocampal MRI-T2 relaxometry.

    abstract:OBJECTIVE:Bilateral hippocampal abnormality is frequent in mesial temporal lobe sclerosis and might affect outcome in epilepsy surgery. The objective of this study was to compare the lateralization of interictal and ictal scalp EEG with MRI T2 relaxometry. MATERIAL AND METHODS:Forty-nine consecutive patients with intr...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.2004.00305.x

    authors: Okujava M,Schulz R,Hoppe M,Ebner A,Jokeit H,Woermann FG

    更新日期:2004-09-01 00:00:00

  • The normal population distribution of PRNP codon 129 polymorphism.

    abstract:OBJECTIVES:The common prion protein gene (PRNP) codon 129 polymorphism modifies the susceptibility to and the phenotype of prion diseases. However, no truly representative normal population-based data, or data stratified according to age or gender are available on the distribution of this polymorphism. MATERIAL AND ME...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0404.2003.00199.x

    authors: Nurmi MH,Bishop M,Strain L,Brett F,McGuigan C,Hutchison M,Farrell M,Tilvis R,Erkkilä S,Simell O,Knight R,Haltia M

    更新日期:2003-11-01 00:00:00

  • Economic consequences of multiple sclerosis for Canadians.

    abstract:OBJECTIVES:To estimate the total costs of multiple sclerosis (MS) for all Canadians in 1994. METHODS:Prevalence-based study estimating disease-related societal costs for Canadians with MS in 1994. The human capital approach was used to estimate the value of lost productivity due to illness. Two components were reveale...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1997.tb00208.x

    authors: Asche CV,Ho E,Chan B,Coyte PC

    更新日期:1997-05-01 00:00:00

  • Urinary noradrenaline and serotonin metabolites in drug-free Parkinson patients and the effect of L-dopa treatment.

    abstract::3-methoxy-4-hydroxyphenylglycol (MHPG) and 5-hydroxyindoleacetic acid (5-HIAA) as well as homovanillic acid (HVA) and cyclic AMP were estimated in the morning urine of 41 drug-free parkinsonian patients and 25 hospitalized controls. In 29 patients, the estimations were repeated after 2 weeks treatment with L-dopa plus...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1982.tb04524.x

    authors: Markianos M,Hadjikonstantinou M,Bistolaki E

    更新日期:1982-08-01 00:00:00

  • Cerebrospinal fluid Flt3 ligand level in patients with amyotrophic lateral sclerosis.

    abstract:OBJECTIVES:The Flt3 ligand (FL) is a cytokine with a neurotrophic and antiapoptotic activity in the central nervous system that induces the survival of neurons. The aim of the study was to measure levels of FL in amyotrophic lateral sclerosis (ALS) patients. MATERIALS AND METHODS:The study involved 23 ALS patients and...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.2006.00704.x

    authors: Iłzecka J

    更新日期:2006-09-01 00:00:00

  • Mood and neural correlates of excessive daytime sleepiness in Parkinson's disease.

    abstract::For patients with Parkinson's disease (PD), excessive daytime sleepiness (PD-EDS) is a debilitating non-motor symptom and may be affected by mood symptoms, especially depression and anxiety. Few neuroimaging works have attempted to identify the neural features of PD-EDS, but various findings were reported. The purpose...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.1111/ane.12704

    authors: Wen MC,Chan LL,Tan LCS,Tan EK

    更新日期:2017-08-01 00:00:00

  • Turns-amplitude analysis and motor unit potential analysis in myasthenia gravis.

    abstract:OBJECTIVES:The aims of this study were to investigate myopathic changes in myasthenia gravis (MG) by using turns-amplitude analysis (TAA) and quantitative motor unit potential duration analysis (MUPan), to correlate myopathic changes with severity and duration of the disease and the results of diagnostic tests includin...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0404.2000.90303.x

    authors: Odabasi Z,Kuruoglu R,Oh SJ

    更新日期:2000-05-01 00:00:00

  • Surgery in primary supratentorial intracerebral hematoma: a meta-analysis of randomized trials.

    abstract:OBJECTIVES:To examine through a meta-analysis whether a treatment strategy of surgery plus the routine medical management saves lives and reduces disability in survivors of primary supratentorial intracerebral hematoma compared to routine medical management alone. MATERIAL AND METHODS:Computerized bibliographic search...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章,meta分析

    doi:10.1111/j.1600-0404.1997.tb00078.x

    authors: Prasad K,Browman G,Srivastava A,Menon G

    更新日期:1997-02-01 00:00:00

  • Outcome following occlusion of the middle cerebral artery.

    abstract::Outcome was studied prospectively in 28 consecutive patients with occlusion of the middle cerebral artery (MCA). They comprise a subgroup of 101 consecutive patients with TIA or stroke less than or equal to 75 years of age, admitted within 72 h after the stroke. Cerebral angiography and CT-scan were performed within 1...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1991.tb04692.x

    authors: Olsen TS

    更新日期:1991-04-01 00:00:00

  • The structural connectivity of the recurrent transient global amnesia.

    abstract:BACKGROUND:One of recent interesting hypotheses of transient global amnesia (TGA) pathophysiology is the preexisting vulnerability of the memory network in patients with TGA. AIM OF THE STUDY:To verify the hypothesis that patients with recurrent amnestic attacks may have more disrupted structural connectivity than pat...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.12518

    authors: Moon Y,Moon WJ,Han SH

    更新日期:2016-08-01 00:00:00

  • The effect of L-Deprenyl on on-off phenomena in Parkinson's disease.

    abstract::L-Deprenyl, a specific monoamine oxidase subtype B inhibitor, has been reported a valuable adjunct to conventional treatment of Parkinsonism. A double-blind cross-over controlled study was performed in 19 parkinsonian patients with on-off type problems. Five mg L-Deprenyl per day reduced the number of on-off episodes....

    journal_title:Acta neurologica Scandinavica

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1600-0404.1985.tb03233.x

    authors: Brodersen P,Philbert A,Gulliksen G,Stigård A

    更新日期:1985-06-01 00:00:00

  • Type I familial amyloid polyneuropathy in a Chinese family.

    abstract::A Chinese family with at least 3 members having the typical clinical picture of type I familial amyloid polyneuropathy is presented. The pathological features, including the immunohistochemical typing of the amyloid deposits, are described and the literature is briefly reviewed. ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1989.tb03806.x

    authors: Chang CM,Yu YL,Wong M,Ng TH,Woo E,Huang CY

    更新日期:1989-05-01 00:00:00

  • Propranolol (Inderal) and clonidine (Catapressan) in the prophylactic treatment of migraine. A comparative trial.

    abstract::Twenty-one patients continued a double-blind crossover study to compare the prophylactic effect on migraine of propranolol and clonidine. The daily dosage of propranolol and clonidine was 160 mg and 100 microgram, respectively. Statistical analysis did not show any significant difference between the two drugs in respe...

    journal_title:Acta neurologica Scandinavica

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1600-0404.1980.tb01504.x

    authors: Kåss B,Nestvold K

    更新日期:1980-06-01 00:00:00

  • Circulating nociceptin and CGRP in medication-overuse headache.

    abstract:BACKGROUND:Previous studies found low serum levels of nociceptin in migraine patients but high serum levels of calcitonin gene-related peptide (CGRP). CGRP can elicit migraine-like headache. Medication-Overuse Headache (MOH) often has migraine features and can mimic chronic migraine. We therefore hypothesized that as i...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.13053

    authors: Munksgaard SB,Ertsey C,Frandsen E,Bendtsen L,Tekes K,Jensen RH

    更新日期:2019-03-01 00:00:00

  • Restless legs syndrome and cerebrovascular/cardiovascular events: Systematic review and meta-analysis.

    abstract:OBJECTIVE:We performed a systematic review and meta-analysis to evaluate the proposed association of restless legs syndrome (RLS) with cerebrovascular/cardiovascular outcomes. METHODS:We calculated the corresponding odds ratios on the prevalence of cerebrovascular/cardiovascular risk factors and standardized mean diff...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/ane.12848

    authors: Katsanos AH,Kosmidou M,Konitsiotis S,Tsivgoulis G,Fiolaki A,Kyritsis AP,Giannopoulos S

    更新日期:2018-01-01 00:00:00

  • High prevalence and increasing incidence of multiple sclerosis in the Norwegian county of Buskerud.

    abstract:OBJECTIVES:The objective was to investigate the incidence of multiple sclerosis (MS) as well as estimate the prevalence as of 1 January 2014 in the southeastern Norwegian county of Buskerud. MATERIALS AND METHODS:All patients with MS living in Buskerud county in Norway between 01 January 2003 and 01 January 2014 were ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.12615

    authors: Simonsen CS,Edland A,Berg-Hansen P,Celius EG

    更新日期:2017-04-01 00:00:00

  • Paraneoplastic neurological syndrome due to burned-out testicular tumor showing hot cross-bun sign.

    abstract:BACKGROUND:Paraneoplastic neurological syndromes (PNS) are rare remote effect of cancer. The antibodies and tumors associated with PNS have been well described, but there are still many clinically suspected cases in which no tumor or antibody can be identified. This is the first report of PNS showing hot cross-bun sign...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.12469

    authors: Ishikawa H,Kawada N,Taniguchi A,Odachi K,Mizutani A,Asahi M,Tomimoto H

    更新日期:2016-05-01 00:00:00