Abstract:
:Giardia duodenalis is a common intestinal parasite in most parts of the world. In Canada it is associated with both endemic and epidemic infections that are often transmitted by the waterborne route. Although G. duodenalis strains have been isolated from several animals, the role of other mammals in human infection is unclear. We have isolated and cultured G. duodenalis trophozoites from domestic and wild animals in Alberta and compared them with a human isolate by protein gel electrophoresis and immunoblot analysis. All strains examined share a similar polypeptide profile and important protein antigens. Prominent antigens of 62, 52, 38, and 31 kilodaltons are conserved. The 52- and 31-kilodalton proteins are the major surface-exposed trophozoite components. The high degree of antigenic sharing among strains from different hosts suggests that there may be a wide range of potential reservoirs for G. duodenalis infections.
journal_name
Can J Microbioljournal_title
Canadian journal of microbiologyauthors
Wenman WM,Meuser RU,Wallis PMdoi
10.1139/m86-171subject
Has Abstractpub_date
1986-12-01 00:00:00pages
926-9issue
12eissn
0008-4166issn
1480-3275journal_volume
32pub_type
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