A longitudinal study of indoor nitrogen dioxide levels and respiratory symptoms in inner-city children with asthma.

abstract：:A patient with massive exposure to tetrachloroethylene fumes presented with coma and severe pulmonary edema. Sequential blood gases, chest x-rays, and clinical findings showed dramatic improvement with conventional but aggressive management and the patient recovered completely. There was no evidence of permanent renal...

journal_title：Environmental health perspectives

authors： Patel R,Janakiraman N,Towne WD

更新日期：1977-12-01 00:00:00

abstract：:Along the Texas-Mexico border, the prevalence of neural tube defects (NTDs) among Mexican-American women doubled during 1990-1991. The human outbreak began during the same crop year as epizootics attributed to exposure to fumonisin, a mycotoxin that often contaminates corn. Because Mexican Americans in Texas consume l...

journal_title：Environmental health perspectives

authors： Missmer SA,Suarez L,Felkner M,Wang E,Merrill AH Jr,Rothman KJ,Hendricks KA

更新日期：2006-02-01 00:00:00

abstract：:Environmental tobacco smoke (ETS) has been associated with cardiovascular mortality. Pathophysiologic pathways leading from ETS exposure to cardiopulmonary disease are still being explored. Reduced cardiac autonomic function, as measured by heart rate variability (HRV), has been associated with cardiac vulnerability a...

journal_title：Environmental health perspectives

authors： Pope CA 3rd,Eatough DJ,Gold DR,Pang Y,Nielsen KR,Nath P,Verrier RL,Kanner RE

更新日期：2001-07-01 00:00:00

abstract：:The destruction of the World Trade Center (WTC) on 11 September 2001 in New York City resulted in the massive release of pulverized dust and combustion products. The dust and smoke settled in the surrounding area, which encompassed a large residential community. We hypothesized that previously normal residents in the ...

journal_title：Environmental health perspectives

authors： Reibman J,Lin S,Hwang SA,Gulati M,Bowers JA,Rogers L,Berger KI,Hoerning A,Gomez M,Fitzgerald EF

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:In animals, some phthalates impair male reproductive development and function. Epidemiological studies have reported inconsistent evidence of associations between phthalates and markers of human testicular function. OBJECTIVES:We aimed to provide estimates of the effects of phthalate exposure on reproductiv...

journal_title：Environmental health perspectives

authors： Joensen UN,Frederiksen H,Blomberg Jensen M,Lauritsen MP,Olesen IA,Lassen TH,Andersson AM,Jørgensen N

更新日期：2012-10-01 00:00:00

abstract：:Haloalkane toxicity originates from attack on biological targets by reactive intermediates derived from haloalkane metabolism by a hemoprotein, cytochrome P-450. Carbon-centered radicals and their peroxyl derivatives are most likely involved. The reactions of iron porphyrin--a model for cytochrome P-450--with various ...

journal_title：Environmental health perspectives

authors： Brault D

更新日期：1985-12-01 00:00:00

abstract：:The physiological function of copper(I)-metallothionein is not well understood. The respiratory function of hemocyanin, a copper(I)-containing respiratory protein found in the hemolymph of many invertebrates, has been known a long time. However, the mechanism by which Cu(I) is inserted into the oxygen-binding site of ...

journal_title：Environmental health perspectives

authors： Brouwer M,Whaling P,Engel DW

更新日期：1986-03-01 00:00:00

abstract：:To examine the effects of dibutyl phthalate (DBP) on gonadal sex differentiation, genetically male tadpoles of Rana rugosa were exposed to dilute solutions of DBP at concentrations of 0.1, 1, or 10 microM during days 19-23 after fertilization, which is the critical period of gonadal sex differentiation in R. rugosa. T...

journal_title：Environmental health perspectives

authors： Ohtani H,Miura I,Ichikawa Y

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:Human controlled-exposure studies have assessed the impact of ambient fine particulate matter on cardiac autonomic function measured by heart rate variability (HRV), but whether these effects are modified by concomitant ozone exposure remains unknown. OBJECTIVE:In this study we assessed the impact of O(3) a...

journal_title：Environmental health perspectives

authors： Fakhri AA,Ilic LM,Wellenius GA,Urch B,Silverman F,Gold DR,Mittleman MA

更新日期：2009-08-01 00:00:00

abstract：:Among the issues dealing with identifying potential adverse immunologic effects (i.e., suppression, hypersensitivity, or autoimmunity) associated with xenobiotic exposure, general agreement exists among the regulatory and pharmaceutical communities that predictive tests for autoimmunity are in most need of development...

journal_title：Environmental health perspectives

authors： Luster MI,Simeonova PP,Gallucci R,Matheson J

更新日期：1999-10-01 00:00:00

abstract：:Fanconi anemia (FA) is an autosomal recessive disorder characterized by diverse developmental abnormalities, progressive bone marrow failure, and a markedly increased incidence of malignancy. FA cells are hypersensitive to DNA cross-linking agents, suggesting a general defect in the repair of DNA cross-links. Some for...

journal_title：Environmental health perspectives

authors： Vilcheck SK,O'Brien TJ,Pritchard DE,Ha L,Ceryak S,Fornsaglio JL,Patierno SR

更新日期：2002-10-01 00:00:00

abstract：:Current research indicates a role for several oncogenes in radiation-induced carcinogenesis in vivo and cell transformation in vitro. Certain oncogenes are probably also involved in some cases of human cancer caused by exposure to nonionizing radiation and may play a mechanistic role in the phenomenon of radioresistan...

journal_title：Environmental health perspectives

authors： Garte SJ,Burns FJ

更新日期：1991-06-01 00:00:00

abstract：:Most of the composites and sealants used in dentistry are based on bisphenol A diglycidylether methacrylate (Bis-GMA). Reports revealed that in situ polymerization is not complete and that free monomers can be detected by different analytic methods. Concerns about the estrogenicity of bisphenol A (BPA) and other aroma...

journal_title：Environmental health perspectives

authors： Pulgar R,Olea-Serrano MF,Novillo-Fertrell A,Rivas A,Pazos P,Pedraza V,Navajas JM,Olea N

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Exposure mixtures frequently occur in data across many domains, particularly in the fields of environmental and nutritional epidemiology. Various strategies have arisen to answer questions about exposure mixtures, including methods such as weighted quantile sum (WQS) regression that estimate a joint effect o...

journal_title：Environmental health perspectives

authors： Keil AP,Buckley JP,O'Brien KM,Ferguson KK,Zhao S,White AJ

更新日期：2020-04-01 00:00:00

abstract：:The metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), the most abundant compound of the aminoimidazoazaarens (AIA) group of mutagens/carcinogens isolated from the crust of fried and broiled meat, was examined in freshly isolated hepatocytes from untreated rat, mouse, hamster, and guinea pig. Activa...

journal_title：Environmental health perspectives

authors： Alexander J,Fossum BH,Holme JA

更新日期：1994-10-01 00:00:00

abstract：:The hypothesis has been put forward that humans and wildlife species adverse suffered adverse health effects after exposure to endocrine-disrupting chemicals. Reported adverse effects include declines in populations, increases in cancers, and reduced reproductive function. The U.S. Environmental Protection Agency spon...

journal_title：Environmental health perspectives

authors： Kavlock RJ,Daston GP,DeRosa C,Fenner-Crisp P,Gray LE,Kaattari S,Lucier G,Luster M,Mac MJ,Maczka C,Miller R,Moore J,Rolland R,Scott G,Sheehan DM,Sinks T,Tilson HA

更新日期：1996-08-01 00:00:00

abstract：:As a result of the Leadership Conference on Biomedical Research and the Environment, the Facilities Committee focused its work on the development of best environmental practices at biomedical research facilities at the university and independent research facility level as well as consideration of potential involvement...

journal_title：Environmental health perspectives

authors： Medlin EL,Grupenhoff JT

更新日期：2000-12-01 00:00:00

abstract：:In 1998 we published the results of a study suggesting an association between breast cancer and perchloroethylene (PCE; also called tetrachloroethylene) exposure from public drinking water. The present case-control study was undertaken to evaluate this association further. The cases were composed of female residents o...

journal_title：Environmental health perspectives

authors： Aschengrau A,Rogers S,Ozonoff D

更新日期：2003-02-01 00:00:00

abstract：:At picomolar concentrations, lead activates protein kinase C (PKC). This activation has been implicated in the neurotoxicity of lead. No prior study has evaluated the association of PKC activity with neurobehavioral function in humans. The purpose of this study was to determine whether PKC activity is associated with ...

journal_title：Environmental health perspectives

authors： Hwang KY,Lee BK,Bressler JP,Bolla KI,Stewart WF,Schwartz BS

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Persistent organic pollutants (POPs) are developmental toxicants, but the impact of both maternal and paternal exposures on offspring birth size is largely unexplored. OBJECTIVE:We examined associations between maternal and paternal serum concentrations of 63 POPs, comprising five major classes of pollutant...

journal_title：Environmental health perspectives

authors： Robledo CA,Yeung E,Mendola P,Sundaram R,Maisog J,Sweeney AM,Barr DB,Louis GM

更新日期：2015-01-01 00:00:00

abstract：:Atlantic coast estuaries recently have experienced fish kills and fish with lesions attributed to Pfiesteria piscicida and related dinoflagellates. Human health effects have been reported from laboratory exposure and from a 1997 Maryland fish kill. North Carolina has recorded Pfiesteria-related fish kill events over t...

journal_title：Environmental health perspectives

authors： Swinker M,Koltai D,Wilkins J,Hudnell K,Hall C,Darcey D,Robertson K,Schmechel D,Stopford W,Music S

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:In a changing climate, increasing temperatures are anticipated to have profound health impacts. These impacts could be mitigated if individuals and communities adapt to changing exposures; however, little is known about the extent to which the population may be adapting. OBJECTIVE:We investigated the hypoth...

journal_title：Environmental health perspectives

authors： Bobb JF,Peng RD,Bell ML,Dominici F

更新日期：2014-08-01 00:00:00

abstract：:Exposure to ultrafine particles (UFPs) from vehicle exhaust has been related to risk of cardiovascular and pulmonary disease and cancer, even though exposure assessment is difficult. We studied personal exposure in terms of number concentrations of UFPs in the breathing zone, using portable instruments in six 18-hr pe...

journal_title：Environmental health perspectives

authors： Vinzents PS,Møller P,Sørensen M,Knudsen LE,Hertel O,Jensen FP,Schibye B,Loft S

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:Tens of millions of Americans suffer from a range of adverse health outcomes due to noise exposure, including heart disease and hearing loss. Reducing environmental noise pollution is achievable and consistent with national prevention goals, yet there is no national plan to reduce environmental noise polluti...

journal_title：Environmental health perspectives

authors： Hammer MS,Swinburn TK,Neitzel RL

更新日期：2014-02-01 00:00:00

abstract：:Pyrethroids are important insecticides used in agriculture, forestry, horticulture, and in the home. In humans, they are rapidly metabolized and renally eliminated. In numerous studies, pyrethroid metabolites have been detected in urine after occupational exposure to insecticides. In this study, we used a new, reliabl...

journal_title：Environmental health perspectives

authors： Heudorf U,Angerer J

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:The Love Canal is a rectangular 16-acre, 10-ft deep chemical waste landfill situated in a residential neighborhood in Niagara Falls, New York. This seriously contaminated site first came to public attention in 1978. No studies have examined mortality in the former residents of the Love Canal neighborhood (LC...

journal_title：Environmental health perspectives

authors： Gensburg LJ,Pantea C,Fitzgerald E,Stark A,Hwang SA,Kim N

更新日期：2009-02-01 00:00:00

abstract：:Exposure to environmental pollutants may contribute to the development of coronary heart disease (CHD). We determined the ZIP codes containing or abutting each of the approximately 900 hazardous waste sites in New York and identified the major contaminants in each. Three categories of ZIP codes were then distinguished...

journal_title：Environmental health perspectives

authors： Sergeev AV,Carpenter DO

更新日期：2005-06-01 00:00:00

abstract：:With this research I tested the hypothesis that individual preferences for specific ecosystem components and restorative environments are significantly associated with quality of life (QOL). A total of 379 human subjects responded to a structured 18-item questionnaire on topophilia and to the 26-item World Health Orga...

journal_title：Environmental health perspectives

authors： Ogunseitan OA

更新日期：2005-02-01 00:00:00

abstract：:Airway mucus is a complex airway secretion whose primary function as part of the mucociliary transport mechanism is to to serve as renewable and transportable barrier against inhaled particulates and toxic agents. The rheologic properties necessary for this function are imparted by glycoproteins, or mucins. Some respi...

journal_title：Environmental health perspectives

authors： Samet JM,Cheng PW

更新日期：1994-06-01 00:00:00

abstract：:Biological markers of intermediate health outcomes sometimes provide a superior alternative to traditional measures of pollutant-related disease. Some opportunities and methodologic issues associated with using markers are discussed in the context of exposures to four complex mixtures: environmental tobacco smoke and ...

journal_title：Environmental health perspectives

authors： Wilcosky TC

更新日期：1993-12-01 00:00:00