Insulin-like growth factors and somatomedin B in the cerebrospinal fluid of patients with dementia of the Alzheimer type.

Abstract:

:Cerebrospinal fluid levels of radioreceptor assayable insulin-like growth factors (RRA-IGFs) and immunoreactive somatomedin B (SMB) (RIA-B) were determined in apparently healthy individuals and in patients with dementia of the Alzheimer type (AD). The CSF levels of RIA-B and RRA-IGFs did not alter from the healthy controls. After being acidified, the CSF from the controls and from the presenile ADs were separated over a G-50 fine Sephadex . The RRA-IGFs activity eluted in three peaks. The results indicate that the major constituent of CSF RRA in both AD patients and controls is an IGF binding protein. The two minor peaks eluted at approximately 9 K and 6 K, corresponding to the elution positions of "big" IGF-2 and IGF-2.

journal_name

Acta Psychiatr Scand

authors

Tham A,Sparring K,Bowen D,Wetterberg L,Sara VR

doi

10.1111/j.1600-0447.1988.tb05193.x

subject

Has Abstract

pub_date

1988-06-01 00:00:00

pages

719-23

issue

6

eissn

0001-690X

issn

1600-0447

journal_volume

77

pub_type

杂志文章
  • Markers for vulnerability to psychopathology: temperament traits associated with platelet MAO activity.

    abstract::The functional linkage between platelet MAO activity and psychopathology was explored by analyzing temperamental correlates in 40 male subjects by means of scales from the Eysenck Personality Questionnaire (EPQ), the Zuckerman Sensation Seeking Inventory, and the Karolinska Scales of Personality (KSP). Linear correlat...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1987.tb02881.x

    authors: Schalling D,Asberg M,Edman G,Oreland L

    更新日期:1987-08-01 00:00:00

  • Are there subtypes of bipolar depression?

    abstract:OBJECTIVE:To investigate for subtypes of bipolar depression using latent class analysis (LCA). METHOD:Participants were recruited through a bipolar disorder (BD) clinic. LCA was undertaken using: (i) symptoms reported on the SCID-IV for the most severe lifetime depressive episode; (ii) lifetime illness features such a...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/acps.12615

    authors: Perich T,Hadzi-Pavlovic D,Frankland A,Breakspear M,Loo C,Roberts G,Holmes-Preston E,Mitchell PB

    更新日期:2016-09-01 00:00:00

  • Labour force activity by people with depression and anxiety disorders: a population-level second-order analysis.

    abstract:OBJECTIVE:To identify the population-level first- and second-order effects among candidate correlates of labour force activity by people with ICD-10 depression and anxiety disorders. METHOD:Australian Bureau of Statistics multistage sampling strategies obtained a household sample of 37,580 individuals. Analyses were c...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.2005.00600.x

    authors: Waghorn G,Chant D

    更新日期:2005-12-01 00:00:00

  • Overdose rates in lithium-treated versus antidepressant-treated outpatients.

    abstract::Our clinical experience that lithium is an agent used infrequently for self-poisoning was investigated. The rate at which such overdoses occurred was determined from hospital records. A retrospective case notes study then compared overdose rates in patients taking lithium versus patients on antidepressant medication. ...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1994.tb01555.x

    authors: Waddington D,McKenzie IP

    更新日期:1994-07-01 00:00:00

  • Prospective data on the prevalence of abnormal involuntary movements among elderly people living in the community.

    abstract::Trained raters from the Liverpool Continuing Health in the Community study interviewed 1070 people over the age of 65 in 1982-1983 using the Geriatric Mental State (GMS) examination. Three years later the cohort was re-interviewed, this time by psychiatrists trained in the GMS, who used the GMS and the History and Aet...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1993.tb03398.x

    authors: Green BH,Dewey ME,Copeland JR,Saunders PA,Sharma V,Larkin B,Davidson IA,Scott A

    更新日期:1993-06-01 00:00:00

  • Change in culture and language environment in childhood and its effect on adult life.

    abstract::During the Second World War 70,000-75,000 Finnish children were sent to Sweden to protect them from the war. This article describes a group of children sent to Sweden from Kuopio County. The management of this group is discussed in light of their health, education and profession in adulthood. The change in culture and...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1989.tb01338.x

    authors: Räsänen E

    更新日期:1989-09-01 00:00:00

  • Clonazepam/haloperidol combination therapy in schizophrenia: a double blind study.

    abstract::Clonazepam (CLN), a benzodiazepine originally used as an anti-epileptic, was tested in schizophrenia in a double blind comparison in combination with haloperidol (HL). Twenty-four schizophrenic inpatients, diagnosed according to DSM III were treated with HL and CLN (Group 1) or HL and placebo (Group 2) for 4 weeks. Th...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1600-0447.1987.tb02942.x

    authors: Altamura AC,Mauri MC,Mantero M,Brunetti M

    更新日期:1987-12-01 00:00:00

  • Dexamethasone suppression and energy balance in eating disorders.

    abstract::The dexamethasone suppression test (DST) was investigated in 45 female anorectic out-patients (cross sectional study) nine of whom were followed serially as in-patients (longitudinal study). DST non-suppression was strongly associated with negative energy balance (low body weight and low Ponderal Index) but there was ...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1986.tb02681.x

    authors: Abou-Saleh MT,Oleesky D,Crisp AH,Lacey JH

    更新日期:1986-03-01 00:00:00

  • Lithium augmentation in sertraline-resistant depression: a preliminary dose-response study.

    abstract::Eleven patients with DSM-III-R major depression who were treatment-resistant to sertraline were allocated for lithium augmentation therapy. In conjunction with their sertraline, 6 received lithium carbonate 400 mg at night and 5 received 800 mg at night. A total of 7 patients responded within 1 week. The degree of res...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1993.tb03461.x

    authors: Dinan TG

    更新日期:1993-10-01 00:00:00

  • Endocrine responses to growth hormone-releasing hormone, thyrotropin-releasing hormone and corticotropin-releasing hormone in depression.

    abstract::To explore and to compare hypothalamic-pituitary-somatotropic (HPS), hypothalamic-pituitary-thyroid (HPT) and hypothalamic-pituitary-adrenocortical (HPA) axis function in depression, 30 subjects (15 patients with a major depressive episode and individually matched controls) received 50 micrograms growth hormone-releas...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1989.tb10308.x

    authors: Lesch KP,Müller U,Rupprecht R,Kruse K,Schulte HM

    更新日期:1989-06-01 00:00:00

  • Immune system-associated antigens on the surface of peripheral blood lymphocytes in patients with Alzheimer's disease.

    abstract::We investigated the immune-associated antigens of peripheral lymphocytes from 13 patients with Alzheimer's disease (AD) and 13 age-matched healthy control subjects using two-color analysis with flow cytometry. Four ratios of immune-related antigens, T/B lymphocytes, CD4/CD8, CD4/CD45R and CD4/HLA-DR, were compared for...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1991.tb05573.x

    authors: Ikeda T,Yamamoto K,Takahashi K,Yamada M

    更新日期:1991-06-01 00:00:00

  • Hallucinations in Kenyan schizophrenic patients.

    abstract::Eighty Kenyan 'psychotic' patients were screened using the New Haven Schizophrenic Index (NHSI) and were all studied for hallucinations using standardised definitions. Fifty-one of the patients were NHSI positive and the rest NHSI negative. Sixty-one percent of the NHSI positive had hallucinations in one or more modal...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1983.tb00334.x

    authors: Ndetei DM,Singh A

    更新日期:1983-03-01 00:00:00

  • Brain functional changes (QEEG cordance) and worsening suicidal ideation and mood symptoms during antidepressant treatment.

    abstract:OBJECTIVE:Antidepressant medications are efficacious overall; however, some individuals experience worsening mood symptoms and increased suicidal ideation (SI) during treatment. We examined the quantitative electroencephalographic (QEEG) cordance biomarker of brain function biomarker in relation to treatment-emergent s...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1600-0447.2010.01560.x

    authors: Hunter AM,Leuchter AF,Cook IA,Abrams M

    更新日期:2010-12-01 00:00:00

  • The influence of premenstrual syndrome on ratings of anxiety in women with generalized anxiety disorder.

    abstract::During the premenstrual and follicular phases of the menstrual cycle, 41 women who had generalized anxiety disorder (GAD) plus premenstrual syndrome (PMS) were assessed with psychiatric rating scales and compared with 21 GAD patients without PMS and 19 controls. The latter two groups were rated only once, in the typic...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1993.tb03451.x

    authors: McLeod DR,Hoehn-Saric R,Foster GV,Hipsley PA

    更新日期:1993-10-01 00:00:00

  • Diagnostic validity of comorbid bipolar disorder and obsessive-compulsive disorder: a systematic review.

    abstract:OBJECTIVE:At least 50% of bipolar disorder (BD) patients have an additional diagnosis, one of the most difficult to manage being obsessive-compulsive disorder (OCD). Defining the nosology of BD-OCD comorbidity has important clinical implications, given that treatments for OCD can worsen BD outcomes. METHOD:A systemati...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.1111/acps.12250

    authors: Amerio A,Odone A,Liapis CC,Ghaemi SN

    更新日期:2014-05-01 00:00:00

  • The Italian mental health reform nine years on.

    abstract::It is 9 years since the mental health reform was passed by the Italian Parliament. The author presents a data-based evaluation of the effects of the Italian mental health reform. There are still many problems to be resolved: More than 30,000 inpatients are still in psychiatric hospitals and little is known of the fate...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1988.tb05163.x

    authors: Crepet P

    更新日期:1988-05-01 00:00:00

  • Adult antisocial personality traits are associated with experiences of low parental care and maternal overprotection.

    abstract:OBJECTIVE:To investigate the role of parenting in the development of adult antisocial personality traits. METHOD:A total of 742 community-based subjects were assessed for adult DSM-IV antisocial personality disorder traits and for measures of parental behavior experienced as children, including by the Parental Bonding...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0447.2002.02305.x

    authors: Reti IM,Samuels JF,Eaton WW,Bienvenu OJ 3rd,Costa PT Jr,Nestadt G

    更新日期:2002-08-01 00:00:00

  • Sleep disorders in patients with severe mental depression: double-blind placebo-controlled evaluation of the value of pipamperone (Dipiperon).

    abstract::Pipamperone was compared double-blindly with placebo to evaluate its capacity to relieve sleep disorders in 40 depressive inpatients. At the end of the 1-week trial, most of the items relating to sleep disturbances had improved significantly in the 24 patients of the pipamperone group whereas only a few items showed s...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1600-0447.1977.tb00147.x

    authors: Ansoms C,Backer-Dierick GD,Vereecken JL

    更新日期:1977-02-01 00:00:00

  • Couvade.

    abstract::In a prospective study a number of women and their husbands were interviewed early on in the pregnancy, in the week after delivery and again 4 months later. The couvade syndrome, in which the father-to-be suffers from somatic symptoms of psychogenic origin connected in some way with his wife's pregnancy, was investiga...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1983.tb06981.x

    authors: Bogren LY

    更新日期:1983-07-01 00:00:00

  • Preliminary results of a fine-grain analysis of mood swings and treatment modalities of bipolar I and II patients using the daily prospective life-chart-methodology.

    abstract:OBJECTIVE:The study aimed to increase the knowledge about the detailed course differences between different forms of bipolar disorder. METHOD:Using the prospective life-chart-clinician version, we compared the fine-grain analysis of mood swings and treatment modalities of 18 bipolar II with 31 bipolar I patients. RES...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.2009.01412.x

    authors: Born C,Seitz NN,Grunze H,Vieta E,Dittmann S,Seemüller F,Amann B

    更新日期:2009-12-01 00:00:00

  • Personality disorders in DSM-III-R as categorical or dimensional.

    abstract::Despite the atheoretical approach of the DSM-III-R, the personality disorders have their roots in specific theoretical schools. Due to clinical tradition, analogies with Axis I and the tradition in psychiatry and medicine, the personality disorders are presented as categories although there is more empirical support f...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1993.tb03436.x

    authors: Ekselius L,Lindström E,von Knorring L,Bodlund O,Kullgren G

    更新日期:1993-09-01 00:00:00

  • The Swedish version of the Positive and Negative Syndrome Scale (PANSS) for schizophrenia. Construct validity and interrater reliability.

    abstract::The Positive and Negative Syndrome Scale (PANSS) has been translated into Swedish and tested in 88 chronic schizophrenic patients. All 4 subscales exhibited a roughly normal distribution. The overall alpha for the positive, negative and general psychopathology subscales were 0.81, 0.58 and 0.63, respectively. The corr...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1111/j.1600-0447.1992.tb03298.x

    authors: von Knorring L,Lindström E

    更新日期:1992-12-01 00:00:00

  • Self-rated schizotypal cognitions, psychotic symptoms and the onset of schizophrenia in young people at high risk of schizophrenia.

    abstract:OBJECTIVE:To examine the associations between the Rust Inventory of Schizotypal Cognitions (RISC) and psychotic symptoms measured by the Present State Examination (PSE) and to assess the predictive validity of the RISC for later onset of schizophrenia. METHOD:A total of 154 subjects at high risk for schizophrenia but ...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0447.2002.1o175.x

    authors: Miller PM,Lawrie SM,Byrne M,Cosway R,Johnstone EC

    更新日期:2002-05-01 00:00:00

  • Female alcoholics. V: The relationship between family history of alcoholism and outcome 3-10 years after treatment.

    abstract::In a long-term follow-up study of 44 female alcoholics, a family history of alcoholism was related to younger age of onset of problem drinking, but did not necessarily imply a poorer outcome within this highly selected group of individuals. Alcoholism in father and his family was not related to either antisocial or bo...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1987.tb02857.x

    authors: Haver B

    更新日期:1987-07-01 00:00:00

  • Suicide attempt predicted by academic performance and childhood IQ: a cohort study of 26 000 children.

    abstract:OBJECTIVE:Academic performance in youth, measured by grade point average (GPA), predicts suicide attempt, but the mechanisms are not known. It has been suggested that general intelligence might underlie the association. METHODS:We followed 26 315 Swedish girls and boys in population-representative cohorts, up to maxim...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/acps.12817

    authors: Sörberg Wallin A,Zeebari Z,Lager A,Gunnell D,Allebeck P,Falkstedt D

    更新日期:2018-04-01 00:00:00

  • Weight gain and obesity in schizophrenia: epidemiology, pathobiology, and management.

    abstract:OBJECTIVE:To review recent advances in the epidemiology, pathobiology, and management of weight gain and obesity in patients with schizophrenia and to evaluate the extent to which they should influence guidelines for clinical practice. METHOD:A Medline literature search was performed to identify clinical and experimen...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.1111/acps.12445

    authors: Manu P,Dima L,Shulman M,Vancampfort D,De Hert M,Correll CU

    更新日期:2015-08-01 00:00:00

  • White matter maturation during 12 months in individuals at ultra-high-risk for psychosis.

    abstract:OBJECTIVE:The neurodevelopmental hypothesis of psychosis suggests that disrupted white matter (WM) maturation underlies disease onset. In this longitudinal study, we investigated WM connectivity and compared WM changes between individuals at ultra-high-risk for psychosis (UHR) and healthy controls (HCs). METHOD:Thirty...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/acps.12835

    authors: Krakauer K,Nordentoft M,Glenthøj BY,Raghava JM,Nordholm D,Randers L,Glenthøj LB,Ebdrup BH,Rostrup E

    更新日期:2018-01-01 00:00:00

  • Serum testosterone levels, mental disorders and criminal behaviour.

    abstract:OBJECTIVE:Although previous studies have revealed an association between androgens and aggression, there is a lack of knowledge of this issue in different mental disorders. METHOD:The associations between serum testosterone levels and criminal behaviour in different mental disorders were examined using data collected ...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1999.tb07240.x

    authors: Räsänen P,Hakko H,Visuri S,Paanila J,Kapanen P,Suomela T,Tiihonen J

    更新日期:1999-05-01 00:00:00

  • Psychotic and behavioural symptoms in a population-based sample of the very elderly subjects.

    abstract:OBJECTIVE:The aim was to elucidate the relationship between psychotic and behavioural symptoms in the elderly. METHOD:A representative sample of 85 year old subjects living in Gothenburg, Sweden (n = 451) was assessed with neuropsychiatric examinations, key informant interviews and record reviews. RESULTS:Fourteen pe...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.2009.01371.x

    authors: Ostling S,Gustafson D,Waern M

    更新日期:2009-08-01 00:00:00

  • Psychoeducational intervention for caregivers of Indian patients with schizophrenia: a randomised-controlled trial.

    abstract:OBJECTIVE:There are hardly any randomised-controlled trials of structured family interventions for schizophrenia from India. This study attempted to evaluate the impact of a structured psychoeducational intervention for schizophrenia, compared with standard out-patient treatment, on various patient- and caregiver-relat...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1600-0447.2008.01304.x

    authors: Kulhara P,Chakrabarti S,Avasthi A,Sharma A,Sharma S

    更新日期:2009-06-01 00:00:00