Lithium augmentation in sertraline-resistant depression: a preliminary dose-response study.

Abstract:

:Eleven patients with DSM-III-R major depression who were treatment-resistant to sertraline were allocated for lithium augmentation therapy. In conjunction with their sertraline, 6 received lithium carbonate 400 mg at night and 5 received 800 mg at night. A total of 7 patients responded within 1 week. The degree of response was not related to the serum lithium level. Patients with lithium levels as low as 0.3 mEq/l responded. No significant side effects were reported.

journal_name

Acta Psychiatr Scand

authors

Dinan TG

doi

10.1111/j.1600-0447.1993.tb03461.x

subject

Has Abstract

pub_date

1993-10-01 00:00:00

pages

300-1

issue

4

eissn

0001-690X

issn

1600-0447

journal_volume

88

pub_type

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