Abstract：
OBJECTIVE:About one-third of patients referred to services for people at high risk for psychosis may have already developed a first episode of psychosis (FEP). We compared clinical outcomes in FEP patients who presented to either high risk or conventional mental health services. METHOD:Retrospective study comparing duration of hospital admission, referral-to-diagnosis time, need for compulsory hospital admission and frequency of admission in patients with FEP who initially presented to a high-risk service (n = 164) to patients with FEP who initially presented to conventional mental health services (n = 2779). Regression models were performed, controlling for several confounders. RESULTS:FEP patients who had presented to a high-risk service spent 17 fewer days in hospital [95% CI: -33.7 to (-0.3)], had a shorter referral-to-diagnosis time [B coefficient -74.5 days, 95% CI: -101.9 to -(47.1)], a lower frequency of admission [IRR: 0.49 (95% CI: 0.39-0.61)] and a lower likelihood of compulsory admission [OR: 0.52 (95% CI: 0.34-0.81)] in the 24 months following referral, as compared to FEP patients who were first diagnosed at conventional services. CONCLUSION:Services for people at high risk for psychosis are associated with better clinical outcomes in patients who are already psychotic.
journal_name
Acta Psychiatr Scandjournal_title
Acta psychiatrica Scandinavicaauthors
Fusar-Poli P,Díaz-Caneja CM,Patel R,Valmaggia L,Byrne M,Garety P,Shetty H,Broadbent M,Stewart R,McGuire Pdoi
10.1111/acps.12480subject
Has Abstractpub_date
2016-01-01 00:00:00pages
76-85issue
1eissn
0001-690Xissn
1600-0447journal_volume
133pub_type
杂志文章abstract：:The validity of DIS-CM (Chinese modified version of Diagnostic Interview Schedule) was examined by analyzing lifetime prevalence of each age group, age at onset, and recency of illness. The magnitude of the discrepancy between the empirical and the estimated data was adopted as the criterion of the degree of deviation...
journal_title：Acta psychiatrica Scandinavica
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doi：10.1111/j.1600-0447.1986.tb02695.x
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abstract：OBJECTIVE:There have been increasing pressures to adopt or incorporate dimensional representations in various sections of DSM-5 including the psychotic disorders section. Thus far, findings offered as evidence of a continuous distribution of psychosis are limited given their exclusive focus on the manifest rather than ...
journal_title：Acta psychiatrica Scandinavica
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abstract：:The marital adjustment of patients with psychogenic pain disorder was evaluated and compared with a matched group of patients with other neurotic disorders. Pain patients spouses were found to have better marital adjustment and less psychiatric morbidity than the spouses of neurotic patients. These findings are discus...
journal_title：Acta psychiatrica Scandinavica
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doi：10.1111/j.1600-0447.1987.tb02769.x
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abstract：:Seven chronic psychiatric patients developed signs of polyneuropathy mainly in the lower limbs after receiving chlorprothixene (500-1800 mg/d) from 3 to more than 24 months. The most prominent electroneuromyographic findings were decreased or not measurable motor conduction velocities of the peroneal nerves. Electromy...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1992.tb08604.x
更新日期：1992-03-01 00:00:00
abstract：:The possible hypersecretion involvement of corticotropin-releasing hormone (CRH) in the pathophysiology of hypothalamic-pituitary-adrenocortical axis disturbances in patients with major depressive episode and with an abnormal dexamethasone suppression test (DST) was investigated. The corticotropin (ACTH) and cortisol ...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1993.tb03344.x
更新日期：1993-02-01 00:00:00
abstract：OBJECTIVE:Children of parents with major depression are at significantly increased risk for developing major depression themselves; however, not all children at genetic risk will develop major depressive disorder (MDD). We investigated the utility of subsyndromal scores on the Child Behavior Checklist (CBCL) Anxiety/De...
journal_title：Acta psychiatrica Scandinavica
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journal_title：Acta psychiatrica Scandinavica
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doi：10.1111/j.1600-0447.1997.tb09658.x
更新日期：1997-05-01 00:00:00
abstract：BACKGROUND:The COVID-19 pandemic in Ireland resulted in a nationwide quarantine on March 27, 2020. This study represents the first assessment of rates of anxiety and depression in the general population of Ireland during the pandemic. AIMS:Our first aim was to estimate the probable prevalence rates of generalized anxi...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/acps.13219
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abstract：OBJECTIVE:There is conflicting data on drug abuse and outcome in severe mental illness. This study aims to investigate if the amount of illicit psychoactive drug use is related to symptom load or premorbid functioning across diagnosis in patients with severe mental illness. METHOD:Symptom load, sociodemographic status...
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pub_type： 杂志文章
doi：10.1111/j.1600-0447.2008.01244.x
更新日期：2008-10-01 00:00:00
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journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1990.tb03053.x
更新日期：1990-09-01 00:00:00
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journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1979.tb00284.x
更新日期：1979-10-01 00:00:00
abstract：:Thirty-seven, out of a sample of 100 elderly subjects, all suffering from dementia, were found to have delusions. The delusions were more common in women, in patients with a history of psychiatric illness, and amongst those with higher information subscores (Blessed Scale); and were less common in patients suffering f...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1985.tb02610.x
更新日期：1985-09-01 00:00:00
abstract：:Twenty-nine depressed elderly patients receiving ECT were randomly assigned to a unilateral or bilateral group; post-ictal recovery times, memory changes, and clinical improvement during and after each course were measured by blind and independent observers. All patients but one showed full recovery on testing 3 weeks...
journal_title：Acta psychiatrica Scandinavica
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1111/j.1600-0447.1980.tb00590.x
更新日期：1980-07-01 00:00:00
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journal_title：Acta psychiatrica Scandinavica
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：
更新日期：2000-03-01 00:00:00
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journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1992.tb03249.x
更新日期：1992-09-01 00:00:00
abstract：:The dexamethasone suppression test (DST) was investigated in 45 female anorectic out-patients (cross sectional study) nine of whom were followed serially as in-patients (longitudinal study). DST non-suppression was strongly associated with negative energy balance (low body weight and low Ponderal Index) but there was ...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1986.tb02681.x
更新日期：1986-03-01 00:00:00
abstract：:Among 1,040 consecutive male criminals remitted for mental examination nine had the karyotype 47,XYY, one 48,XXYY and eleven 47,XXY. The types of crime in the XYY men were much like those in the XXY men, the proportion of sexual crimes possibly being greater than among other criminal offenders. The reasons for these f...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1981.tb00674.x
更新日期：1981-03-01 00:00:00
abstract：OBJECTIVE:Describe potential cardiac complications of low-dose quetiapine and other atypical antipsychotic drugs. METHOD:We present a case report of a 45-year-old Black woman with multiple medical and psychiatric problems taking low-dose quetiapine. RESULTS:Coincident with a generalized seizure, the patient developed...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.2005.00592.x
更新日期：2005-10-01 00:00:00
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journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1990.tb05459.x
更新日期：1990-04-01 00:00:00
abstract：:The author describes a 22-year-old male who suffered from chronic severe Obsessive-Compulsive Neurosis (OCN) complicated by frequent depressive episodes. Administering the monoamine oxidase inhibitor phenelzine in high dosage led to complete alleviation of his depression in 10 weeks, and 3 weeks afterwards the OCN was...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1987.tb02779.x
更新日期：1987-02-01 00:00:00
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journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1988.tb06371.x
更新日期：1988-10-01 00:00:00
abstract：:Neuroleptic side-effects adversely affect clinical outcome in schizophrenic patients. Clinicians therefore require an understanding of the impact of such side-effects. This study compared psychiatrists' estimates of the prevalence of neuroleptic side-effects and associated distress with schizophrenic patients' reports...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1998.tb09969.x
更新日期：1998-01-01 00:00:00
abstract：OBJECTIVE:Lithium-neuroleptics induced encephalopathy is a rare drug interaction. Here I am reporting a patient who developed reversible encepatholopathy with lithium-risperidone combination. METHOD:A single case report. RESULT:A patient of bipolar disorder, who presented with manic symptoms with psychotic feature, s...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.2008.01165.x
更新日期：2008-05-01 00:00:00
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journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1977.tb00154.x
更新日期：1977-03-01 00:00:00
abstract：:The purpose of the present study is to determine the frequency of polypharmacy among psychiatric patients in Helsinki, and to ascertain whether this practice is supported by clinical trials. The drugs prescribed in 1 day to a sample of patients (n = 694) in mental hospitals and outpatient clinics in Helsinki were stud...
journal_title：Acta psychiatrica Scandinavica
pub_type： 临床试验,杂志文章
doi：10.1111/j.1600-0447.1977.tb06676.x
更新日期：1977-11-01 00:00:00
abstract：OBJECTIVE:This study was designed to investigate the association between major mental disorders (MMDs) and homicide. METHOD:The rates of exculpations because of MMDs among 1087 Austrian homicide offenders during 1975 and 1999 were compared with the rates of the respective disorders in the general population. RESULTS:...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0047.2004.00305.x
更新日期：2004-08-01 00:00:00
abstract：OBJECTIVE:Despite comparable antipsychotic exposure, some patients experience involuntary movements yet others do not. Negative symptoms have been associated with tardive dyskinesia (TD), but it is not certain whether this is an association with primary negative symptoms or the effects of medications. The aim of the pr...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.2011.01751.x
更新日期：2011-11-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to determine the prevalence of personality disorders in a group of elderly patients without an organic mental disorder and to examine the relationship between the Temperament and Character Inventory (TCI) and personality disorder symptoms in psychogeriatric clinical practice. METHOD...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1999.tb10865.x
更新日期：1999-10-01 00:00:00
abstract：:Psychological autopsies are an important research tool in establishing risk factors associated with suicide. We report the results of a validity study comparing psychological autopsy-generated DSM-III-R diagnoses in suicides and non-suicides with chart diagnoses generated by clinicians who had treated the subjects pri...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1996.tb09869.x
更新日期：1996-11-01 00:00:00
abstract：OBJECTIVE:The endocannabinoid (EC) system is widely distributed throughout the brain and modulates many functions. It is involved in mood and related disorders, and its activity may be modified by exogenous cannabinoids. This article examines the therapeutic potential of cannabinoids in psychiatric disorders. METHOD:A...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章,评审
doi：10.1111/j.1600-0447.2011.01687.x
更新日期：2011-10-01 00:00:00
