Encephalopathy with combined lithium-risperidone administration.

Abstract:

OBJECTIVE:Lithium-neuroleptics induced encephalopathy is a rare drug interaction. Here I am reporting a patient who developed reversible encepatholopathy with lithium-risperidone combination. METHOD:A single case report. RESULT:A patient of bipolar disorder, who presented with manic symptoms with psychotic feature, started with a combination of lithium and risperidone. Within few days, the patient developed encepatholopathy, which reversed upon discontinuation of lithium and risperidone. CONCLUSION:Combining lithium and neuroleptic is useful in treatment of bipolar disorder. However, encepatholapthy can be anticipated to result when lithium is used with high potency anti-psychotic such as haloperidol and risperidone and there are baseline EEG abnormalities.

journal_name

Acta Psychiatr Scand

authors

Boora K,Xu J,Hyatt J

doi

10.1111/j.1600-0447.2008.01165.x

subject

Has Abstract

pub_date

2008-05-01 00:00:00

pages

394-5; discussion 396

issue

5

eissn

0001-690X

issn

1600-0447

pii

ACP1165

journal_volume

117

pub_type

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