Abstract:
OBJECTIVE:There is conflicting data on drug abuse and outcome in severe mental illness. This study aims to investigate if the amount of illicit psychoactive drug use is related to symptom load or premorbid functioning across diagnosis in patients with severe mental illness. METHOD:Symptom load, sociodemographic status, premorbid functioning and the level of use of illicit psychoactive drugs were assessed in 423 subjects with schizophrenia or bipolar disorder in a cross-sectional study. RESULTS:High amount of illicit drug use was associated with poorer premorbid academic functioning. In schizophrenia, there was a significant positive association between amount of drug use and severity of psychiatric symptoms. The association between symptom load and drug use was significant after controlling for premorbid functioning. CONCLUSION:The results suggest a direct association between the quantity of current drug use and more severe symptoms in schizophrenia. Poor premorbid functioning was related to high amount of use, but did not explain the difference in symptom load.
journal_name
Acta Psychiatr Scandjournal_title
Acta psychiatrica Scandinavicaauthors
Ringen PA,Melle I,Birkenaes AB,Engh JA,Faerden A,Vaskinn A,Friis S,Opjordsmoen S,Andreassen OAdoi
10.1111/j.1600-0447.2008.01244.xsubject
Has Abstractpub_date
2008-10-01 00:00:00pages
297-304issue
4eissn
0001-690Xissn
1600-0447pii
ACP1244journal_volume
118pub_type
杂志文章abstract::A total of 1814 patients were studied from the Mississippi State Hospital with a DSM-III diagnosis of schizophrenia and aged 15-39 years at the time of admission. The 634 schizophrenics with a birth date between 1 December and 31 March were compared with the 1180 born between 1 April and 30 November for age of admissi...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1991.tb03152.x
更新日期:1991-10-01 00:00:00
abstract::The attitude of the medical profession to psychiatry carries important implications for the quality of personnel attracted into the specialty and for the treatment, in a general medical setting, of patients with mental disorders. This article examines the components of doctors' attitudes and reviews the literature wit...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0447.1992.tb01432.x
更新日期:1992-01-01 00:00:00
abstract:OBJECTIVE:Renewed insight into dose-related effects of sertindole and haloperidol was sought by re-analysing published data for antipsychotic effect, extrapyramidal effect, and patient wellbeing - i.e., the important pharmacopsychometric triangle domains. METHOD:Selected Positive and Negative Syndrome Scale (PANSS) su...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/j.1600-0447.2010.01581.x
更新日期:2011-02-01 00:00:00
abstract:OBJECTIVE:'Crisis cards' state patients' treatment details and preferences in anticipation of a later occasion when the patient might be too ill to express them directly. We assessed the feasibility of introducing 'crisis cards', or a collaborative form of them, 'joint crisis plans', into a sectorized community psychia...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1999.tb10914.x
更新日期:1999-07-01 00:00:00
abstract:OBJECTIVE:To determine the long-term social function of psychiatric patients with anxiety and depressive disorders and to relate this to personality status and other factors. METHOD:A cohort of 210 patients (mean age 35 years) with dysthymic disorder, generalized anxiety disorder or panic disorder diagnosed using a st...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1046/j.1600-0447.2003.00241.x
更新日期:2004-02-01 00:00:00
abstract::224 newly admitted inpatients were randomly allocated to two treatment groups: standard care (length of stay determined by the clinical team) and brief care (acute treatment aimed at effecting the patient's discharge after about a week). Using a new research instrument (the Patient Behaviour Assessment Schedule), info...
journal_title:Acta psychiatrica Scandinavica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1600-0447.1981.tb00658.x
更新日期:1981-02-01 00:00:00
abstract::Within the framework of the multifactorial-polygenic model of inheritance, multiple threshold strategy was applied to a large set of pedigree data to examine the clinico-genetical position of some subtypes within the ICD-9 classification of schizophrenic psychoses. It appeared highly probable that the ICD-9 subtypes e...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1983.tb07009.x
更新日期:1983-10-01 00:00:00
abstract:OBJECTIVE:To examine whether the development of tardive dyskinesia (TD) is accompanied by a parallel process of worsening negative symptoms in a longitudinal study. METHOD:A sample of 708 psychotic patients were followed over a period of 2 years, using the Abnormal Involuntary Movement Scale and the Scale for the Asse...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:
更新日期:2000-04-01 00:00:00
abstract::The author describes a 22-year-old male who suffered from chronic severe Obsessive-Compulsive Neurosis (OCN) complicated by frequent depressive episodes. Administering the monoamine oxidase inhibitor phenelzine in high dosage led to complete alleviation of his depression in 10 weeks, and 3 weeks afterwards the OCN was...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1987.tb02779.x
更新日期:1987-02-01 00:00:00
abstract::The efficacy and the safety of moclobemide (400-600 mg/day), a reversible and selective inhibitor of monoamine oxidase-A (RIMA) and of clomipramine (100-150 mg/day) were compared respectively in 98 and 93 nonmelancholic, nonpsychotic out-patients with a DSM-III major depressive episode over 6 weeks and up to 3 months,...
journal_title:Acta psychiatrica Scandinavica
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1111/j.1600-0447.1995.tb09580.x
更新日期:1995-10-01 00:00:00
abstract::The Department of Psychiatry, University Hospital, Lund, is in possession of systematic clinical ratings from 1949 to 1969 based on a multi-dimensional diagnostic schedule. All 1312 first-admitted patients (120 women) from the county who were rated as "chronic alcohol intoxication" were followed up until 31 December, ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1984.tb01228.x
更新日期:1984-11-01 00:00:00
abstract::Quality of life (QOL) was assessed in three groups of patients, consisting of 30 schizophrenic patients with duration of illness <2 years, 30 schizophrenic patients with duration of illness > or = 2 years and 30 dysthymic patients. The diagnoses were made according to ICD-10. Two scales of quality of life were used, o...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1998.tb10002.x
更新日期:1998-04-01 00:00:00
abstract:OBJECTIVE:To date only five reports of neuroleptic malignant syndrome (NMS) related to olanzapine exist. The first case report was published in November 1998. METHOD:We report the case of a 78-year-old woman suffering from chronic schizophrenia who developed a NMS while being treated with olanzapine and levomepromazin...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1034/j.1600-0447.2000.102003231.x
更新日期:2000-09-01 00:00:00
abstract:OBJECTIVE:Serving military can be regarded as exposure to a moderate enforced stressor independent of other vulnerability factors. The aims of this study were i) to explore psychiatric morbidity and mortality during 10 years of follow-up in a cohort of healthy adolescent Danish conscripts and ii) to investigate whether...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.2007.01129.x
更新日期:2008-02-01 00:00:00
abstract::This investigation studied by direct interviews in a randomly selected sample of 58 Swedish unbroken families, factors of importance for the father's experience of his preschool child. The father's experience of his child was shown to correlate with the child's experience of him. Fathers experiencing their child in a ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1980.tb00563.x
更新日期:1980-01-01 00:00:00
abstract::A case of organic brain syndrome occurring in relation to psychological stress 2 years after a severe head injury is described. Treatment with haloperidol resulted only in slight improvement. A dramatic improvement was achieved with carbamazepine. ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1988.tb05136.x
更新日期:1988-03-01 00:00:00
abstract::A prospective 1-year study was conducted in 69 patients with affective disorder. Despite remission, there was a significant continued presence at each visit of major symptoms of mania and depression and of mean mood shift. Furthermore, sub-clinical affective symptoms, as determined by General Behavior Inventory self-r...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1987.tb02841.x
更新日期:1987-06-01 00:00:00
abstract:OBJECTIVE:Although previous studies have revealed an association between androgens and aggression, there is a lack of knowledge of this issue in different mental disorders. METHOD:The associations between serum testosterone levels and criminal behaviour in different mental disorders were examined using data collected ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1999.tb07240.x
更新日期:1999-05-01 00:00:00
abstract:OBJECTIVE:Our analysis aimed at comparing the placebo effect sizes from randomized controlled trials (RCTs) of two widely prescribed antidepressants, namely duloxetine and venlafaxine, and at analysing a potential influence of the investigated drugs on the placebo response. METHOD:We conducted a comprehensive systemat...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,meta分析
doi:10.1111/acps.12881
更新日期:2018-06-01 00:00:00
abstract:OBJECTIVE:To examine the association between physical and mental disorders and the separate and joint effect of physical and mental disorders on work-loss. METHOD:Data was derived from the Netherlands Mental Health Survey and Incidence Study. This was a general population study in which 7076 adults, aged between 18 an...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.2005.00513.x
更新日期:2005-06-01 00:00:00
abstract::We investigated the renal function (urine volume, glomerular filtration rate, urinary osmolality and proteinuria) of 50 patients chronically treated with lithium carbonate for major affective disorder. No patient had any alteration in the parameters considered. No relationship was found between any of the parameters s...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1989.tb10295.x
更新日期:1989-05-01 00:00:00
abstract:OBJECTIVES:To differentiate the relation between the structure and timing of rest-activity patterns and symptoms of impulsivity and mood instability in bipolar disorder (BD), borderline personality disorder (BPD) and healthy controls (HC). METHODS:Eighty-seven participants (31 BD, 21 BPD and 35 HC) underwent actigraph...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/acps.13148
更新日期:2020-04-01 00:00:00
abstract:OBJECTIVE:The aims of this study were (i) to assess the inter-rater reliability of the latest Italian expanded 24-item version of the Brief Psychiatric Rating Scale, BPRS version 4.0 and (ii) to assess the feasibility of obtaining reliable BPRS 4.0 ratings by reliability training of clinically less experienced trainees...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1999.tb10850.x
更新日期:1999-09-01 00:00:00
abstract:OBJECTIVE:In a previous magnetic resonance imaging (MRI) study, we found a significant increase in hippocampal volume immediately after electroconvulsive therapy (ECT) in patients with depression. The aim of this study was to evaluate hippocampal volume up to 1 year after ECT and investigate its possible relation to cl...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/acps.12150
更新日期:2014-04-01 00:00:00
abstract::A retrospective study was made, investigating the post-treatment outcomes of patients in two apparently dissimilar psychiatric therapeutic centres in Nigeria: the Aro Mental Hospital, a custodial facility, and the Aro Community Village Program, a pilot experiment in community psychiatry. A matches sample of 208 treate...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1977.tb00135.x
更新日期:1977-01-01 00:00:00
abstract:OBJECTIVE:To provide meta-analytical evidence of bone mineral density (BMD), fractures, and osteoporosis rates in eating disorders (ED) vs. healthy controls (HCs). METHOD:Three independent authors searched major electronic databases from inception till August 2015 for cross-sectional studies reporting BMD in people wi...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,meta分析,评审
doi:10.1111/acps.12556
更新日期:2016-05-01 00:00:00
abstract:OBJECTIVE:To study adult mental health in offspring of mothers who experienced severe puerperal disorder. METHOD:Mothers, followed up a mean of 23 years after puerperal disorder requiring hospitalization, were interviewed regarding adult psychiatric illness, childhood neurotic symptoms and conduct problems of 48 offsp...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.2004.00406.x
更新日期:2004-11-01 00:00:00
abstract:OBJECTIVE:This study used voxel-based morphometry (VBM) to investigate brain structural alterations related to trait dissociation and its relationship with post-traumatic stress disorder (PTSD). METHOD:Thirty-two subjects either developing (N = 15) or non-developing (N = 17) PTSD underwent MRI scanning and were assess...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/acps.12026
更新日期:2013-09-01 00:00:00
abstract::A multi-variate multiple regression analysis was carried out to screen the crucial characteristics of alcohol abusers immediately prior to pension in order to indicate their subsequent trends. Stepwise multiple regression analyses were performed in the younger and older subgroups, as well as in 56 first-time pension a...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1983.tb00951.x
更新日期:1983-12-01 00:00:00
abstract:OBJECTIVE:The impact of religious/spiritual activities on clinical outcomes in patients with serious mental illnesses remains controversial, which was addressed in this international cross-sectional study. METHOD:Three-hundred sixty-nine subjects were recruited from Austria (n = 189) and Japan (n = 180), consisting of...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,多中心研究
doi:10.1111/acps.12838
更新日期:2018-04-01 00:00:00