Abstract:
OBJECTIVE:This study used voxel-based morphometry (VBM) to investigate brain structural alterations related to trait dissociation and its relationship with post-traumatic stress disorder (PTSD). METHOD:Thirty-two subjects either developing (N = 15) or non-developing (N = 17) PTSD underwent MRI scanning and were assessed with the Dissociative Experience Scale (DES), subscales for pathological (DES-T) and non-pathological trait (DES-A) dissociation, and other clinical measures. Gray matter volume (GMV) was analyzed using VBM as implemented in SPM. PTSD and non-PTSD subjects were compared to assess brain alterations related to PTSD pathology, whereas correlation analyses between dissociation measures and GMV were performed on the whole sample (N = 32), irrespective of PTSD diagnosis, to identify alterations related to trait dissociation. RESULTS:As compared to traumatized controls, PTSD subjects showed reduced GMV in the prefrontal cortex, hippocampus and lingual gyrus. Correlations with dissociation measures (DES, DES-T, and DES-A) consistently showed increased GMV in the medial and lateral prefrontal, orbitofrontal, parahippocampal, temporal polar, and inferior parietal cortices. CONCLUSION:PTSD and dissociation seem to be associated with opposite volumetric patterns in the prefrontal cortex. Trait dissociation appears to involve increased GMV in prefrontal, paralimbic, and parietal cortices, with negligible differences between pathological and non-pathological dissociation.
journal_name
Acta Psychiatr Scandjournal_title
Acta psychiatrica Scandinavicaauthors
Nardo D,Högberg G,Lanius RA,Jacobsson H,Jonsson C,Hällström T,Pagani Mdoi
10.1111/acps.12026subject
Has Abstractpub_date
2013-09-01 00:00:00pages
222-33issue
3eissn
0001-690Xissn
1600-0447journal_volume
128pub_type
杂志文章abstract:OBJECTIVE:This study examines concurrent associations of attachment security, psychopathology and recollections of early parental interactions, in adults with obsessive-compulsive disorder (OCD), depression, and in healthy controls. METHOD:Thirty-six out-patients with OCD, 16 depressed out-patients and 26 controls wer...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0047.2004.00271.x
更新日期:2004-06-01 00:00:00
abstract::Koro is an acute anxiety reaction in which the perception of decreased penis length because of intra-abdominal traction is the main feature. This study attempts to explore the penis-root perception of the Koro patients by a graphomotor projective test--the Draw-a-penis Test (DAPT). This controlled DAPT investigation s...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1991.tb01413.x
更新日期:1991-07-01 00:00:00
abstract:OBJECTIVE:There is conflicting data on drug abuse and outcome in severe mental illness. This study aims to investigate if the amount of illicit psychoactive drug use is related to symptom load or premorbid functioning across diagnosis in patients with severe mental illness. METHOD:Symptom load, sociodemographic status...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.2008.01244.x
更新日期:2008-10-01 00:00:00
abstract::A mild form of neuroleptic malignant syndrome (NMS) in a schizophrenic patient who was receiving a depot neuroleptic is described and beneficial response to oral diazepam 50 mg daily is reported. ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1988.tb06355.x
更新日期:1988-09-01 00:00:00
abstract:OBJECTIVE:This paper presents evidence of new developments in the detection and treatment of perinatal mood and anxiety disorders that have relevance for clinicians. METHOD:An electronic search was conducted in MEDLINE, CINAHL, PsychINFO and The Cochrane Library Database for the interval 1995-2005 for papers published...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0447.2005.00549.x
更新日期:2005-08-01 00:00:00
abstract:OBJECTIVE:Non-suicidal self-injury (NSSI) comprising thoughts and behaviors is common and often co-occurring with suicidal behavior like ideation, plan, and attempt. As limited data are available for adolescents and young adults, this study aims to present prevalence estimates for lifetime NSSI, its co-occurrence with ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/acps.13237
更新日期:2020-12-01 00:00:00
abstract::Sleep disturbances commonly occur in the premenstruum in both Premenstrual Syndrome (PMS) patients and in women from the general population. Reports on the Post-Sleep Inventory were obtained from a clinic sample of PMS patients and samples from the general population dichotomized into a non-clinic group with and witho...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1988.tb06304.x
更新日期:1988-07-01 00:00:00
abstract::One hundred people with autistic disorder (DSM-III-R) without a known cause who comprised a total population of children with autism were compared with "autistic-like" children, Asperger syndrome and age-matched comparison children from the general population and were examined with regard to month of birth. There was ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1990.tb01373.x
更新日期:1990-08-01 00:00:00
abstract::Patients receiving lithium who had noticed changes in hair texture since starting that drug, described variously as hair losing its curl or wave, have a greater lithium concentration in hair than patients on lithium with no such complaints. ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1985.tb02626.x
更新日期:1985-10-01 00:00:00
abstract::Plasma concentrations of barbital and diazepam were measured daily during a double-blind study of the efficacy of the two drugs in the treatment of delirium tremens and less severe clinical states. Treatment was estimated as satisfactory in the majority of cases; the present study deals with the satisfactory groups on...
journal_title:Acta psychiatrica Scandinavica
pub_type: 临床试验,杂志文章
doi:10.1111/j.1600-0447.1979.tb06966.x
更新日期:1979-03-01 00:00:00
abstract::The associations between milieu therapists' feelings towards patients and the unit's psychological climate were studied at 21 small treatment homes for severely disturbed psychiatric patients. The milieu therapists filled out self-report instruments where they rated their feelings towards patients on a feeling-word ch...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1996.tb10650.x
更新日期:1996-04-01 00:00:00
abstract::Previous research in neuroendocrinology has evidenced that hyperactivity of the hypothalamic-pituitary-adrenal axis (HPA) depends on hypersecretion of corticotropin-releasing hormone (CRH). The aim of this study was to investigate the activity of HPA before and after recovery in depressed patients treated with electro...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1990.tb03053.x
更新日期:1990-09-01 00:00:00
abstract::Therapeutic relationship has been considered an important ingredient of all psychotherapies. In communities in which no familiar conventions of such a relationship are available, the therapeutic encounter poses very different problems from those in the West, where such conventions freely prevail. This study has been c...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1985.tb02547.x
更新日期:1985-06-01 00:00:00
abstract::This investigation studied by direct interviews in a randomly selected sample of 58 Swedish unbroken families, factors of importance for the father's experience of his preschool child. The father's experience of his child was shown to correlate with the child's experience of him. Fathers experiencing their child in a ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1980.tb00563.x
更新日期:1980-01-01 00:00:00
abstract:OBJECTIVE:To investigate psychiatric outcomes after bariatric surgery, including suicide, self-harm, psychiatric service use and substance misuse. METHOD:Retrospective study on a Danish nationwide register-based cohort of 22 451 patients followed for 1 029 736 person-years. Data were analysed utilizing single- and mul...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/acps.12669
更新日期:2017-02-01 00:00:00
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journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1998.tb10122.x
更新日期:1998-12-01 00:00:00
abstract:OBJECTIVE:To determine the number of attempts it took before patients with a first episode of psychosis received adequate help, the signs or symptoms that led them to seek help and the people from whom they attempted to seek help. METHOD:Subjects were 86 individuals with a schizophrenia spectrum disorder, mainly schiz...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1034/j.1600-0447.2002.02004.x
更新日期:2002-11-01 00:00:00
abstract:OBJECTIVE:The amygdala plays a major role in processing emotional stimuli. Fourteen studies using structural magnetic resonance imaging (MRI) have examined the amygdala volume in paediatric and adult patients with bipolar disorder (BD) compared with healthy controls (HC) and reported inconsistent findings. Lithium has ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.2009.01428.x
更新日期:2010-02-01 00:00:00
abstract::A study of suicide among the nonnomadic Gypsies in three counties in Hungary revealed that they had a lower completed suicide rate but a higher attempted suicide rate than ethnic Hungarians. The rate of attempted suicide appeared to be higher in the younger, partially assimilated Gypsies as a result of the conflict be...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1990.tb01405.x
更新日期:1990-11-01 00:00:00
abstract::We present a case of priapism caused by the alpha adrenoreceptor blocking action of a butyrophenone. The problem was solved surgically performing a cavernousspongiosum fistula. ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1988.tb05086.x
更新日期:1988-01-01 00:00:00
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journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/acps.12720
更新日期:2017-06-01 00:00:00
abstract::Suicide was a crime in England and Wales until 1961. This paper compares the English legal treatment of suicide with that in other Western countries. The delayed English decriminalization of suicide is a likely result of the nature of English common law, rather than a reflection of actual public opinion and medico-leg...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0447.1996.tb09857.x
更新日期:1996-10-01 00:00:00
abstract::alpha 1 antitrypsin deficiency (ATD) predisposes the individual for serious lung disease in adulthood. The identification of ATD by neonatal screening was hypothesized to have negative long-term effects on the parents' attitudes and feelings associated with the child. This hypothesis was tested by comparing these atti...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1986.tb06252.x
更新日期:1986-10-01 00:00:00
abstract::Regional brain glucose metabolism was determined in 9 male alcohol-dependent inpatients and 12 male healthy controls. All the patients were socially impaired by the alcohol abuse. All the subjects had abstained from alcohol and drugs for more than four weeks before entering the study. Brain glucose metabolism was dete...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1988.tb06330.x
更新日期:1988-08-01 00:00:00
abstract::EEG and EMG were monitored simultaneously at 72 ECT sessions in 18 patients. When EMG was recorded from the leg the duration of EMG curve convulsions varied between 43 and 89% of the EEG recorded seizure duration of the same fit. The EMG/EEG seizure ratio varied widely among different patients as well as within the si...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1981.tb00775.x
更新日期:1981-09-01 00:00:00
abstract::Antidepressants are ineffective in about 30% of patients with major depression. Some authors then advise treatment of non-responders with (non-tricyclic) more selective reuptake inhibitors. In a double-blind, partial crossover study, 71 patients were selected for treatment during 4 weeks with oxaprotiline and/or fluvo...
journal_title:Acta psychiatrica Scandinavica
pub_type: 临床试验,杂志文章
doi:10.1111/j.1600-0447.1988.tb06402.x
更新日期:1988-12-01 00:00:00
abstract::The aim of the study was to examine the social and economic variables associated with mental health by means of telephone interviews of a randomly chosen population sample (n = 1557) in Finland in 1993. Mental health was evaluated by means of a 12-item General Health Questionnaire. A mental disorder, indicated by the ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1995.tb09570.x
更新日期:1995-09-01 00:00:00
abstract::In Denmark about 11-12 per 100,000 population are diagnosed as schizophrenics for the first time each year. Less than half of these receive this diagnosis at first admission and therefore only 5-6 per 100,000 are included in the official schizophrenia incidence figures. In a cohort (n = 53), predictors for diagnosis o...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1989.tb10275.x
更新日期:1989-04-01 00:00:00
abstract::Zuclopenthixol decanoate (ZPT-D) and haloperidol decanoate (HAL-D) were compared in the maintenance treatment of chronic schizophrenic patients. All patients were treated with either ZPT-D or HAL-D for at least 3 months and were then randomly allocated to treatment with either ZPT-D (100-600 mg every 4 weeks) or HAL-D...
journal_title:Acta psychiatrica Scandinavica
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1111/j.1600-0447.1991.tb01414.x
更新日期:1991-07-01 00:00:00
abstract:OBJECTIVE:The primary aim of the study was to compare the effectiveness of group and individual cognitive behaviour therapy (CBT) for obsessive compulsive disorder (OCD). METHOD:One hundred and ten out-patients with OCD were randomly assigned to 15 sessions of either group CBT or individual CBT. Outcome measures were ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,meta分析,随机对照试验
doi:10.1111/j.1600-0447.2010.01613.x
更新日期:2011-05-01 00:00:00