Abstract:
OBJECTIVE:Selective outcome reporting poses serious implications on our evidence base for best practice. The extent to which selective outcome reporting and trial registration occurs in the wider psychotherapy literature needs to be investigated. METHOD:Randomized controlled psychotherapy trials published between 2010 and 2014 were selected from the five highest impact factor journals in clinical psychology that publish clinical trials. Data on primary and secondary outcomes, funding, and participant numbers were extracted from the article and registry and compared. RESULTS:From 112 trials, 67 (59.8%) were registered, 27 (24.1%) were prospectively registered, and only 13 (11.6%) were correctly registered and reported. Seven of these 13 trials showed evidence of selective outcome reporting, of which four had discrepancies favoring significant outcomes. One of the remaining six trials changed their primary outcomes during participant enrollment. Overall, only five (4.5%) trials were free from selective outcome reporting. Three of these five trials had more than a 10% change between planned and achieved sample size. Funding was not associated with correct registration or reporting. CONCLUSIONS:The proportion of psychotherapy randomized controlled trials correctly registered and transparently reported is poor. Psychologists should consider the impact these results have on public confidence in reported outcomes.
journal_name
Acta Psychiatr Scandjournal_title
Acta psychiatrica Scandinavicaauthors
Bradley HA,Rucklidge JJ,Mulder RTdoi
10.1111/acps.12647subject
Has Abstractpub_date
2017-01-01 00:00:00pages
65-77issue
1eissn
0001-690Xissn
1600-0447journal_volume
135pub_type
杂志文章,评审abstract::The study comprised 26 patients with somatic symptoms indicating a hernia-reflux syndrome referred to a university hospital ear, nose and throat department. The aim was to throw light on the hypothesis that this syndrome is largely a psychosomatic problem. The patients were divided into two groups: subjects with and w...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1986.tb10590.x
更新日期:1986-02-01 00:00:00
abstract::The validity of a questionnaire developed to assess negative attitudes towards drug therapy by relatives of schizophrenic patients is examined. The questionnaire items are tested against the statement: "Patients should not take drugs, they can only be helped by good advice". The prejudice of relatives of schizophrenic...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1985.tb01269.x
更新日期:1985-02-01 00:00:00
abstract:OBJECTIVE:There is ongoing concern about the possible negative impact of ECT on neurocognitive functioning in older patients. In this study, we aimed to characterize the long-term cognitive effects of ECT in patients with late-life depression, using an extensive neuropsychological battery. METHODS:A total of 110 patie...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/acps.12942
更新日期:2018-09-01 00:00:00
abstract:OBJECTIVE:To identify risk factors associated with cycle acceleration (CA), that is, progressive decrease in duration of syndrome-free intervals between affective episodes, in acutely admitted patients with bipolar disorder (BD). METHOD:All patients (n = 210) with BD I (67%) and BD II (33%) (DSM-IV) acutely admitted t...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/acps.12308
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:Serving military can be regarded as exposure to a moderate enforced stressor independent of other vulnerability factors. The aims of this study were i) to explore psychiatric morbidity and mortality during 10 years of follow-up in a cohort of healthy adolescent Danish conscripts and ii) to investigate whether...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.2007.01129.x
更新日期:2008-02-01 00:00:00
abstract:OBJECTIVE:To identify possible differences in the mean midsagittal corpus callosum (CC) total and subdivision areas in treatment-resistant schizophrenia and depression (TRS and TRD) patients. METHOD:Areas of the total CC and its five equidistant subregions (from CC1 to CC5) obtained by parallel grid partitioning schem...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.2009.01389.x
更新日期:2009-10-01 00:00:00
abstract:OBJECTIVE:To identify the early signs of mood disorder development, specifically bipolar disorder (BD), in a population at familial risk for BD. METHOD:The sample included 107 Dutch adolescent bipolar offspring (age 12-21) followed into adulthood (age 22-32). Lifetime DSM-IV axis I diagnoses were examined at baseline,...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/acps.12739
更新日期:2017-08-01 00:00:00
abstract::Serum levels of total L-tryptophan (L-TP) were determined before and during treatment in patients suffering from endogenous depression, who were treated with L-TP, 6 g daily, and unilateral electroconvulsive therapy (ECT). The gaussian curve of initial L-TP concentrations changed into a bimodal distribution during tre...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1979.tb00260.x
更新日期:1979-07-01 00:00:00
abstract::A 23-year-old male with a history of severe Tourette syndrome refractory to treatment with oral haloperidol is reported. The Tourette symptoms remitted after treatment with haloperidol decanoate. The response has been maintained over 18 months. ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1988.tb05159.x
更新日期:1988-04-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the efficacy of zotepine in the treatment of acute episodes of schizophrenia. METHOD:Patients with acute exacerbation of schizophrenia (DSM-III-R criteria; n = 158) were allocated on a random, double-blind basis to receive zotepine (150 or 300 mg/day), chlorpromazine (30...
journal_title:Acta psychiatrica Scandinavica
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:
更新日期:2000-03-01 00:00:00
abstract::In a population survey in Stockholm, 224 dementia cases were staged using two scales: the Washington University Clinical Dementia Rating Scale and DSM III-R. Both scales had to be modified by adding additional specifications and, in the case of DSM III-R, a new category of questionable dementia. After modification, th...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1992.tb03225.x
更新日期:1992-07-01 00:00:00
abstract:OBJECTIVE:The study aimed to characterize neuropsychiatric symptomatology and its evolution in a large group of poststroke patients during their first year. METHOD:The Neuropsychiatric Inventory (NPI) was administered to a sample of 124 poststroke patients, divided into three independent groups on the basis of time fr...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1600-0447.2004.00297.x
更新日期:2004-07-01 00:00:00
abstract:OBJECTIVE:Treatment of schizophrenia is frequently complicated by patients' ambivalence and lack of insight into the disease, occasionally warranting involuntary treatment. This study aims to describe involuntary treatment in Danish schizophrenia patients. METHOD:Patients diagnosed with a lifetime ICD-10 F20 schizophr...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/acps.12144
更新日期:2014-04-01 00:00:00
abstract:OBJECTIVE:The aim of this review is to summarize all data on suicidal behaviour reported in the Bible and to discuss basic implications for medical ethical positions. METHOD:All books of the Jerusalem Bible, including the apocrypha accepted in the Catholic canon, were searched for all cases of suicide, attempted suici...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.2005.00567.x
更新日期:2005-09-01 00:00:00
abstract::Review of recent literature with emphasis on growth, development and epidemiology of eating disorders and diabetes reveals many common features of the conditions. Thus we hypothesize more concurrence than would occur by chance alone. At present epidemiological evidence is inconclusive, but prevalence of eating disorde...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1987.tb02819.x
更新日期:1987-05-01 00:00:00
abstract:BACKGROUND:A higher incidence of childhood trauma (CT) has been reported in first episode of psychosis (FEP). There is, however, a lack of knowledge about the synergetic effect between CT and recent stressful events (RSE). METHODS:Information on specific types of CT (under 17 years) and RSE (within the past 3 years) w...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/acps.13114
更新日期:2020-01-01 00:00:00
abstract::The relationship between brain density, measured by computerized tomography (CT), and severity of depression was investigated in 44 patients with a major depressive episode according to DSM-III. In order to limit methodological problems, correlations between both the Brief Psychiatric Rating Scale (BPRS) and the Bech-...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1988.tb06392.x
更新日期:1988-11-01 00:00:00
abstract:OBJECTIVE:The amygdala plays a major role in processing emotional stimuli. Fourteen studies using structural magnetic resonance imaging (MRI) have examined the amygdala volume in paediatric and adult patients with bipolar disorder (BD) compared with healthy controls (HC) and reported inconsistent findings. Lithium has ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.2009.01428.x
更新日期:2010-02-01 00:00:00
abstract::In a prospective study a number of women and their husbands were interviewed early on in the pregnancy, in the week after delivery and again 4 months later. The couvade syndrome, in which the father-to-be suffers from somatic symptoms of psychogenic origin connected in some way with his wife's pregnancy, was investiga...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1983.tb06981.x
更新日期:1983-07-01 00:00:00
abstract:OBJECTIVE:Cannabis is an acknowledged risk factor for some mental disorders, but for others the evidence is inconclusive. Prescribed medicinal drugs can be used as proxies for mental disorders. In this study, we investigate how use of cannabis is prospectively related to prescription of antipsychotics, mood stabilizers...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/acps.13104
更新日期:2020-02-01 00:00:00
abstract:OBJECTIVE:To evaluate morbidity during long-term follow-up with clinical treatment of affective and schizoaffective disorder subjects followed from hospitalization for first major psychotic episodes. METHODS:We followed adult subjects systematically at regular intervals from hospitalization for first-lifetime episodes...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/acps.13243
更新日期:2021-01-01 00:00:00
abstract:OBJECTIVE:To study the outcome of a sequential treatment protocol in elderly, severely depressed in-patients. METHOD:All 81 patients from a 12-week double-blind randomized controlled trial (RCT) comparing venlafaxine with nortriptyline were asked to participate in a 3 year follow-up study. Thirty-two patients who did ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1600-0447.2008.01295.x
更新日期:2009-04-01 00:00:00
abstract:OBJECTIVE:In this paper, we aimed at reviewing evidence-based treatment options for bipolar mania and proposed tentative evidence-based clinical suggestions regarding the management of a manic episode, especially regarding the choice of the proper mood stabilizer and antipsychotic medication. METHOD:A narrative review...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/acps.13209
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVE:The study examined to what degree schizophrenia is characterized by a neuropsychological (NP) test profile specific in shape and level compared with depression and normal functioning. METHOD:Fifty-three patients with schizophrenia, 45 with non-psychotic depression, and 50 normals were assessed with a compreh...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.2005.00626.x
更新日期:2006-04-01 00:00:00
abstract:OBJECTIVE:To compare the service use and costs of individuals who have a dual diagnosis of psychosis and substance abuse with those who have a diagnosis of psychosis but no substance abuse. METHOD:Patients with psychosis were identified and a representative sample were interviewed. Six-month service use was measured a...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1034/j.1600-0447.2000.101006464.x
更新日期:2000-06-01 00:00:00
abstract::Pneumoencephalography (PEG) was carried out in 50 patients of both sexes consecutively discharged from a psychiatric department with a diagnosis of acute schizophrenia. At clinical follow-up with a mean observation time of 8 years the diagnosis was verified in 38 patients, while 12 were considered to have had a reacti...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1982.tb06719.x
更新日期:1982-11-01 00:00:00
abstract::A total 215 first-degree relatives of 88 twin probands with schizophrenia, mood disorders and nonaffective psychoses were studied. The twins' parents and siblings were personally interviewed with structured diagnostic instruments and diagnosed in accordance with DSM-III-R criteria. The first-degree relatives were inte...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1991.tb05577.x
更新日期:1991-06-01 00:00:00
abstract::We studied whether regular treatment with tranquilizing and hypnotic drugs among 30,344 twins in Sweden 15-47 years old was associated with robust indicators of poor health. Longitudinal psychiatric diagnoses and subsequent suicides were analyzed with data from cross-sectional health questionnaires. Women were almost ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1990.tb03072.x
更新日期:1990-12-01 00:00:00
abstract::Antidepressants are ineffective in about 30% of patients with major depression. Some authors then advise treatment of non-responders with (non-tricyclic) more selective reuptake inhibitors. In a double-blind, partial crossover study, 71 patients were selected for treatment during 4 weeks with oxaprotiline and/or fluvo...
journal_title:Acta psychiatrica Scandinavica
pub_type: 临床试验,杂志文章
doi:10.1111/j.1600-0447.1988.tb06402.x
更新日期:1988-12-01 00:00:00
abstract:OBJECTIVE:The neurodevelopmental hypothesis of psychosis suggests that disrupted white matter (WM) maturation underlies disease onset. In this longitudinal study, we investigated WM connectivity and compared WM changes between individuals at ultra-high-risk for psychosis (UHR) and healthy controls (HCs). METHOD:Thirty...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/acps.12835
更新日期:2018-01-01 00:00:00