Abstract：
:We investigated the capacity of several thyroid-axis measures to distinguish between depressed and control subjects and determined whether these variables were related to antidepressant treatment response. We studied 105 subjects who fulfilled the DSM-III-R criteria for a current major depressive episode and 41 volunteers with no current mental disorder. The following thyroid-axis variables were measured: difference between T4 levels at 09.00 hours and 13.00 hours; baseline TSH; maximal TSH response to 400 micrograms TRH (delta max TSH); and presence of a blunted delta max TSH. The T4 difference variable alone distinguished between depressed and control subjects. In multivariate analyses, T4 difference and delta max TSH were independently related to antidepressant-treatment outcome, and predicted a modest proportion (14%) of the variance in outcome. The relationship between these two variables and treatment outcome was particularly strong in depressed male subjects who were receiving desipramine, for whom they accounted for 36% of the variance in treatment outcome. The T4 difference variable both distinguished between depressed and control subjects and was related to treatment outcome. Although this finding requires replication, it is consistent with other reports of the usefulness of thyroid-axis indices measured at different times of day in depressed patients.
journal_name
Acta Psychiatr Scandjournal_title
Acta psychiatrica Scandinavicaauthors
Sullivan PF,Wilson DA,Mulder RT,Joyce PRdoi
10.1111/j.1600-0447.1997.tb09648.xsubject
Has Abstractpub_date
1997-05-01 00:00:00pages
370-8issue
5eissn
0001-690Xissn
1600-0447journal_volume
95pub_type
杂志文章abstract：OBJECTIVE:Despite comparable antipsychotic exposure, some patients experience involuntary movements yet others do not. Negative symptoms have been associated with tardive dyskinesia (TD), but it is not certain whether this is an association with primary negative symptoms or the effects of medications. The aim of the pr...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.2011.01751.x
更新日期：2011-11-01 00:00:00
abstract：:Efficacy and side effects of flurazepam 15 mg, fosazepam 60 mg, and nitrazepam 5 mg were studied in 17 psychogeriatric patients. The drugs were equipotent in maintaining sleep but nitrazepam had more side effects than the other hypnotics, and it induced a rebound insomnia after withdrawal. All hypnotics lost some of t...
journal_title：Acta psychiatrica Scandinavica
pub_type： 临床试验,杂志文章
doi：10.1111/j.1600-0447.1978.tb06871.x
更新日期：1978-01-01 00:00:00
abstract：:The case of an autopsied patient with hypophyseal prolactinoma and dermatozoic delusions is reported, and the mechanism of onset of this special form of delusion is discussed from the neuroendocrinological view point, including response to medications, and neuropathological and pituitary hormonal studies. The subject ...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1985.tb02641.x
更新日期：1985-11-01 00:00:00
abstract：:Serum levels of total L-tryptophan (L-TP) were determined before and during treatment in patients suffering from endogenous depression, who were treated with L-TP, 6 g daily, and unilateral electroconvulsive therapy (ECT). The gaussian curve of initial L-TP concentrations changed into a bimodal distribution during tre...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1979.tb00260.x
更新日期：1979-07-01 00:00:00
abstract：:109 killers, 38 nonviolent offenders and 54 community controls were compared on psychiatric diagnosis, the MMPI, Cattell 16 PF, IQ and clinical neurological results. Killers did not differ from nonviolent offenders on diagnosis or personality in general. Only higher MMPI Hysteria scale scores differentiated the killer...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1982.tb00930.x
更新日期：1982-09-01 00:00:00
abstract：:Salivary secretion was measured in 54 psychiatric patients comprising four diagnostic groups: schizophrenia, mania, depression and anxiety state. Detailed psychometric assessment was carried out at the time of measurement. Although salivary flow failed to show an association with either diagnostic category or mental s...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1979.tb00253.x
更新日期：1979-05-01 00:00:00
abstract：OBJECTIVE:This study examined the co-occurrence of anxiety/mood and personality disorders (PDs) in substance abusers, the impact of anxiety/ mood disorders on the symptom profiles of PDs, and the impact of anxiety/mood disorders and PDs on pre-treatment status. METHOD:Current anxiety/mood disorders and PDs and pre-tre...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1034/j.1600-0447.2000.90050.x
更新日期：2000-02-01 00:00:00
abstract：:The rates of middle ear disease in 70 patients with schizophrenia from a defined catchment population were compared with the rates in 359 nonpsychiatric controls who were matched for age, sex and general practice. A relative risk (odds ratio) of middle ear disease in schizophrenia of 1.92 was found. This was raised to...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1995.tb09771.x
更新日期：1995-04-01 00:00:00
abstract：:The availability of confiding persons both within and outside the household has been investigated in a series of 110 depressed patients and of 98 non-psychiatric controls. The depressive sample has been classified into diagnostic subgroups of unipolar, bipolar, reactive-neurotic and unspecified type of depression. The...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1984.tb01194.x
更新日期：1984-08-01 00:00:00
abstract：OBJECTIVE:Literature suggests that childhood trauma increases vulnerability for schizophrenia-spectrum disorders, including schizotypal personality disorder (SPD). Yet, it remains unexplored whether childhood trauma predicts symptom load and the level of neurocognitive functioning in SPD. METHOD:We included 225 indivi...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/acps.13032
更新日期：2019-07-01 00:00:00
abstract：:An increased death rate has been found in patients treated in hospital for neurosis but the reasons for this are not known. A case note study is described in which 37 patients who were treated in hospital for neurosis and subsequently died are compared with a cross-matched sample of treated neurotics who were alive at...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1979.tb06970.x
更新日期：1979-03-01 00:00:00
abstract：:Ten patients with manic psychosis were compared with 20 normal subjects with respect to their ratings of emotional meaning in music. As stimulus two pieces of music for a small symphony orchestra were used. These were structurally identical but performed at two different tempos: slow and fast. The change in tempo was ...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1982.tb00825.x
更新日期：1982-02-01 00:00:00
abstract：:Based on the theory of Henry & Short, it was predicted that suicide rates should be higher and homicide rates lower in countries where the quality of life is better. In 1980, for a sample of 43 countries, this prediction was confirmed for some components of the quality of life (psychological well-being) but not for ot...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1990.tb05459.x
更新日期：1990-04-01 00:00:00
abstract：:Demographic data, personal and familial characteristics, as well as DSM-III-R-based psychiatric diagnoses were collected in 369 adolescents and young adults aged between 15 and 29 years, referred to an Emergency Department for psychological problems. In total, 60% of them were suicide attempters. Separations before th...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1998.tb10122.x
更新日期：1998-12-01 00:00:00
abstract：OBJECTIVE:Auditory verbal hallucinations (AVHs) are core features of psychotic illness and remain significant in predicting poor outcome and risk. There has been a wide range of approaches to understanding these experiences. METHOD:A systematic literature review summarizing different methods of investigation and their...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章,评审
doi：10.1111/acps.12531
更新日期：2016-05-01 00:00:00
abstract：:Paranoid states beginning in middle life were selected from a case register. A search among the sibs of those probands uncovered no paranoid states and schizophrenia was no more common than in the general population. The implications for the aetiology of paranoid states and for the relationship between these and schiz...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1980.tb00880.x
更新日期：1980-05-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to further evaluate the oestrogen hypothesis of schizophrenia, which postulates low oestradiol levels to be a risk factor for these disorders. A possible influence of neuroleptic-induced hyperprolactinaemia was to be addressed. METHOD:Sex hormones were measured and cycle phase asses...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1046/j.1600-0447.2003.00251.x
更新日期：2004-04-01 00:00:00
abstract：OBJECTIVE:Several studies have found an increase in hippocampal volume following electroconvulsive therapy (ECT), but the effect on cortical thickness has been less investigated. We aimed to examine the effects of ECT on cortical thickness and their associations with clinical outcome. METHOD:Using 3 Tesla MRI scanner,...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/acps.13068
更新日期：2019-09-01 00:00:00
abstract：OBJECTIVE:To determine the prevalence, psychiatric comorbidity and suicidal ideation associated with co-occurring non-affective psychosis and panic attacks, compared with non-affective psychosis without panic attacks, in the general population. METHOD:Data were drawn from the National Comorbidity Survey (n = 8098). St...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1034/j.1600-0447.2002._10424.x
更新日期：2002-01-01 00:00:00
abstract：OBJECTIVE:To determine the prevalence of depression in a community with 15 000 inhabitants in Brazil (Bambuí). METHOD:The Composite International Diagnostic Interview was applied in a random sample of 1041 residents aged 18+ years. RESULTS:The ICD-10 1-month, 1-year and lifetime prevalences of depression were 8.2% (9...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1034/j.1600-0447.2001.00440.x
更新日期：2001-10-01 00:00:00
abstract：:We conducted a 25-year follow-up study of 50 children of schizophrenic mothers, consisting of 25 children reared by their mothers and 25 children reared apart. The children's adult psychiatric status was evaluated in a 3-h structured interview employing a battery of syndrome check-lists and scales. A slightly higher i...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1997.tb09936.x
更新日期：1997-11-01 00:00:00
abstract：:419 patients in Sri Lanka, 150 patients in U.K. and 172 patients in Canada who were suffering from "Functional Psychoses" were interviewed using the Present State Examination to elicit Schneider's First Rank Symptoms (FRS). Nationality and ethnicity were found to be significant variables associated with lower prevalen...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1987.tb02921.x
更新日期：1987-11-01 00:00:00
abstract：OBJECTIVE:To identify possible differences in the mean midsagittal corpus callosum (CC) total and subdivision areas in treatment-resistant schizophrenia and depression (TRS and TRD) patients. METHOD:Areas of the total CC and its five equidistant subregions (from CC1 to CC5) obtained by parallel grid partitioning schem...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.2009.01389.x
更新日期：2009-10-01 00:00:00
abstract：:Combined data from double-blind risperidone studies were used to analyse the severity of extrapyramidal symptoms (EPS) associated with treatment in patients with chronic schizophrenia. Factors associated with maximum EPS severity were increasing risperidone dose (< or = 8 mg/day was similar to placebo), lower baseline...
journal_title：Acta psychiatrica Scandinavica
pub_type： 临床试验,杂志文章
doi：10.1111/j.1600-0447.1999.tb00972.x
更新日期：1999-03-01 00:00:00
abstract：:The validity of a questionnaire developed to assess negative attitudes towards drug therapy by relatives of schizophrenic patients is examined. The questionnaire items are tested against the statement: "Patients should not take drugs, they can only be helped by good advice". The prejudice of relatives of schizophrenic...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1985.tb01269.x
更新日期：1985-02-01 00:00:00
abstract：OBJECTIVE:To test the hypothesis that not only intrafamiliar childhood abuses inflicted to the patient, but also major losses or other severe life events suffered by the mother within 2 years of patient's birth, are risk factors for the development of dissociative disorders (DDs). METHOD:A multicentric case-control st...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章,多中心研究
doi：10.1034/j.1600-0447.2002.01062.x
更新日期：2002-02-01 00:00:00
abstract：:Previous research in neuroendocrinology has evidenced that hyperactivity of the hypothalamic-pituitary-adrenal axis (HPA) depends on hypersecretion of corticotropin-releasing hormone (CRH). The aim of this study was to investigate the activity of HPA before and after recovery in depressed patients treated with electro...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1990.tb03053.x
更新日期：1990-09-01 00:00:00
abstract：OBJECTIVE:There have been increasing pressures to adopt or incorporate dimensional representations in various sections of DSM-5 including the psychotic disorders section. Thus far, findings offered as evidence of a continuous distribution of psychosis are limited given their exclusive focus on the manifest rather than ...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.2011.01800.x
更新日期：2012-01-01 00:00:00
abstract：:367 new cases of drug abuse and related cases were admitted to the teaching hospital within the study period. These cases comprised approximately 11% of all new admissions during the period. 80% were between 15 and 30 years, and 76% of them were single. People in this age group tend to abuse cannabis and amphetamine m...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1986.tb06234.x
更新日期：1986-07-01 00:00:00
abstract：:The validity of DIS-CM (Chinese modified version of Diagnostic Interview Schedule) was examined by analyzing lifetime prevalence of each age group, age at onset, and recency of illness. The magnitude of the discrepancy between the empirical and the estimated data was adopted as the criterion of the degree of deviation...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1986.tb02695.x
更新日期：1986-04-01 00:00:00
