Markers for vulnerability to psychopathology: temperament traits associated with platelet MAO activity.

Abstract:

:The functional linkage between platelet MAO activity and psychopathology was explored by analyzing temperamental correlates in 40 male subjects by means of scales from the Eysenck Personality Questionnaire (EPQ), the Zuckerman Sensation Seeking Inventory, and the Karolinska Scales of Personality (KSP). Linear correlations were found with two sensation seeking scales, replicating earlier findings. However, nonlinear correlations predominated. Subjects with intermediate platelet MAO activity had higher scores in conformity scales and lower scores in anxiety and hostility scales than low and high MAO subgroups. Low MAO subjects showed a pattern of higher scores in KSP Impulsiveness, EPQ Neuroticism, and KSP Somatic Anxiety and Irritability and lower scores in KSP Socialization, in line with personality profiles found in alcoholics, psychopaths, and suicide attempters who also tend to have low platelet MAO activity. High MAO subjects scored lower in sensation seeking and conformity scales and higher in KSP Psychasthenia, Muscular Tension and Suspicion scales, consistent with clinical links between high platelet MAO activity and anxiety and paranoia.

journal_name

Acta Psychiatr Scand

authors

Schalling D,Asberg M,Edman G,Oreland L

doi

10.1111/j.1600-0447.1987.tb02881.x

subject

Has Abstract

pub_date

1987-08-01 00:00:00

pages

172-82

issue

2

eissn

0001-690X

issn

1600-0447

journal_volume

76

pub_type

杂志文章
  • The Family Questionnaire (FQ): a scale for measuring symptom appraisal in relatives of schizophrenic patients.

    abstract:OBJECTIVE:This study examined the psychometric properties of the Family Questionnaire (FQ): a self-report measure of relatives' perceptions of the behaviours and symptoms of schizophrenic patients in terms of three dimensions: the frequency of symptoms, the relatives' concern (primary appraisal) and their ability to co...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 临床试验,杂志文章

    doi:10.1034/j.1600-0447.2003.00156.x

    authors: Quinn J,Barrowclough C,Tarrier N

    更新日期:2003-10-01 00:00:00

  • Subthreshold and threshold attention deficit hyperactivity disorder symptoms in childhood: psychosocial outcomes in adolescence in boys and girls.

    abstract:OBJECTIVE:To examine the association between different levels of childhood attention deficit hyperactivity disorder (ADHD) symptoms and sex differences in psychosocial outcomes during adolescence. METHOD:Swedish children (n = 4635) were screened for neuropsychiatric symptoms at age 9 or 12. ADHD symptoms were divided ...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/acps.12655

    authors: Norén Selinus E,Molero Y,Lichtenstein P,Anckarsäter H,Lundström S,Bottai M,Hellner Gumpert C

    更新日期:2016-12-01 00:00:00

  • Lithium and hair texture.

    abstract::Patients receiving lithium who had noticed changes in hair texture since starting that drug, described variously as hair losing its curl or wave, have a greater lithium concentration in hair than patients on lithium with no such complaints. ...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1985.tb02626.x

    authors: McCreadie RG,Farmer JG

    更新日期:1985-10-01 00:00:00

  • A 15-year follow-up study of Chinese schizophrenic patients.

    abstract::A cohort of 330 Chinese schizophrenic patients below age 40 were interviewed 5, 10 and 15 years later to determine which variables could predict their outcome. There were 189 males (57%) and 141 females (43%). At the end of 15 years, 48 (15%) died (34 (10%) from suicide). At the end of 5, 10 and 15 years, the percenta...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1991.tb03132.x

    authors: Tsoi WF,Wong KE

    更新日期:1991-09-01 00:00:00

  • A review and meta-analysis of the patient factors associated with psychiatric in-patient aggression.

    abstract:OBJECTIVE:To combine the results of earlier comparison studies of in-patient aggression to quantitatively assess the strength of the association between patient factors and i) aggressive behaviour,ii) repetitive aggressive behaviour. METHOD:A systematic review and meta-analysis of empirical articles and reports of com...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/acps.12053

    authors: Dack C,Ross J,Papadopoulos C,Stewart D,Bowers L

    更新日期:2013-04-01 00:00:00

  • Panic attacks in psychosis.

    abstract:OBJECTIVE:To determine the prevalence, psychiatric comorbidity and suicidal ideation associated with co-occurring non-affective psychosis and panic attacks, compared with non-affective psychosis without panic attacks, in the general population. METHOD:Data were drawn from the National Comorbidity Survey (n = 8098). St...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0447.2002._10424.x

    authors: Goodwin R,Davidson L

    更新日期:2002-01-01 00:00:00

  • Prospective investigations of the prodromal state of schizophrenia: review of studies.

    abstract:OBJECTIVE:The paper presents a comprehensive overview of prospective studies monitoring or intervening in the pre-onset phase of first episode psychosis. METHOD:A systematic literature search was conducted and supplemented by a manual search. All relevant studies were ordered and intensively reviewed according to spec...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.1111/j.1600-0447.2005.00697.x

    authors: Olsen KA,Rosenbaum B

    更新日期:2006-04-01 00:00:00

  • Survival analysis of suicide risk after attempted suicide.

    abstract::Survival analysis of suicide risk by sex and age after attempted suicide was studied in a cohort of 1573 suicide attempters referred to the psychiatric emergency room at the Karolinska Hospital from 1981 to 1988. The time course of suicide risk and the overall prognosis after attempted suicide and, in particular, the ...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1995.tb09791.x

    authors: Nordström P,Samuelsson M,Asberg M

    更新日期:1995-05-01 00:00:00

  • Is anhedonia a good measure of depression?

    abstract::The symptom of anhedonia, or loss of pleasure, is widely recognized to occur in depression. More recently it has been suggested that this symptom alone might be the basis for a diagnosis of depression in medically ill patients, and the Hospital Anxiety and Depression Scale (HAD) has been designed with this in mind. To...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1991.tb05534.x

    authors: Silverstone PH

    更新日期:1991-04-01 00:00:00

  • Treatment strategy in depression. I. Non-tricyclic and selective reuptake inhibitors in resistant depression: a double-blind partial crossover study on the effects of oxaprotiline and fluvoxamine.

    abstract::Antidepressants are ineffective in about 30% of patients with major depression. Some authors then advise treatment of non-responders with (non-tricyclic) more selective reuptake inhibitors. In a double-blind, partial crossover study, 71 patients were selected for treatment during 4 weeks with oxaprotiline and/or fluvo...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1600-0447.1988.tb06402.x

    authors: Nolen WA,van de Putte JJ,Dijken WA,Kamp JS,Blansjaar BA,Kramer HJ,Haffmans J

    更新日期:1988-12-01 00:00:00

  • The clinical genetics of Pick's disease.

    abstract::The families of 11 probands with Pick's disease as determined by histopathological examination, were investigated by interview and acquisition of medical records. The estimated morbid risk was 0.25 +/- 0.08 for parents and 0.07 +/- 0.07 for siblings or probands. Further analyses are presented that seek associations be...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1978.tb06886.x

    authors: Heston LL

    更新日期:1978-03-01 00:00:00

  • Childhood experiences and personality traits in patients with motor conversion symptoms.

    abstract::A total of 30 patients with newly diagnosed motor conversion disorder were consecutively investigated by means of a Swedish self-rating inventory designed to assess perceived parental rearing practices (EMBU), and the Karolinska Scale of Personality (KSP). DSM Axis I and II psychopathology was assessed using a Structu...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1998.tb10086.x

    authors: Binzer M,Eisemann M

    更新日期:1998-10-01 00:00:00

  • Hope in psychiatry: a review of the literature.

    abstract:OBJECTIVE:Hope has long been considered an important therapeutic factor in medicine, nursing and mental health and recently received attention as a central component of recovery. However, conceptual clarity, applicability and the predictive value of hope remain unclear. This review aims to define hope, review current a...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.1111/j.1600-0447.2008.01271.x

    authors: Schrank B,Stanghellini G,Slade M

    更新日期:2008-12-01 00:00:00

  • Metabolic syndrome and drug discontinuation in schizophrenia: a randomized trial comparing aripiprazole olanzapine and haloperidol.

    abstract:OBJECTIVE:To determine whether the prescription of aripiprazole, compared with olanzapine and haloperidol, was associated with a lower frequency of metabolic syndrome (MS) and treatment discontinuation at 1 year. METHOD:Patients were randomly assigned to be treated open-label and according to usual clinical practice w...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/acps.12468

    authors: Parabiaghi A,Tettamanti M,D'Avanzo B,Barbato A,GiSAS study group.

    更新日期:2016-01-01 00:00:00

  • The bipolar-borderline personality disorders connection in major depressive patients.

    abstract:OBJECTIVE:The study focuses on the controversial relationship between borderline personality disorder (BPD) and bipolar disorder (BD), defined according to different criteria set, in a world-wide sample of patients with a current major depressive episode (MDE). METHOD:A total of 5635 patients with an MDE were enrolled...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章,多中心研究

    doi:10.1111/acps.12083

    authors: Perugi G,Angst J,Azorin JM,Bowden C,Vieta E,Young AH,BRIDGE Study Group.

    更新日期:2013-11-01 00:00:00

  • Schizophrenia: a study comparing a family therapy group following a paradoxical model plus psychodrugs and a group treated by the conventional clinical approach.

    abstract::A 'short family therapy' in schizophrenia, according to a specific systemic model (the 'Elementary Pragmatic Model' or EPM) with a strong paradoxical structure is presented. A total of 38 schizophrenic patients, randomly allocated, were treated according to the EPM model combined with psychotropic drugs (19 cases, eac...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1600-0447.1997.tb09618.x

    authors: De Giacomo P,Pierri G,Santoni Rugiu A,Buonsante M,Vadruccio F,Zavoianni L

    更新日期:1997-03-01 00:00:00

  • Effect of illness expression and liability on familial associations of clinical and subclinical psychosis phenotypes.

    abstract:OBJECTIVE:Given the familial influences on schizophrenia, it may be hypothesized that specific symptom domains also cluster within families, and that this applies to both clinical and subclinical levels of expression. This hypothesis was put to the test in a group of patients with a DSM-IV diagnosis of psychotic disord...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/acps.12102

    authors: Lataster T,Verweij K,Viechtbauer W,GROUP.

    更新日期:2014-01-01 00:00:00

  • Expressed emotion: a Swedish version of the Camberwell Family Interview.

    abstract::A Swedish version of the Camberwell Family Interview (CFI), a psychiatric, semistructured interview schedule for assessing a family's emotional atmosphere, is described. Thirty-two relatives of patients with schizophrenic disorders, according to DSM-III criteria, were interviewed. Eighteen relatives were interviewed t...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1991.tb03179.x

    authors: Orhagen T,d'Elia G

    更新日期:1991-11-01 00:00:00

  • A remarkable response of chronic severe obsessive-compulsive neurosis to phenelzine.

    abstract::The author describes a 22-year-old male who suffered from chronic severe Obsessive-Compulsive Neurosis (OCN) complicated by frequent depressive episodes. Administering the monoamine oxidase inhibitor phenelzine in high dosage led to complete alleviation of his depression in 10 weeks, and 3 weeks afterwards the OCN was...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1987.tb02779.x

    authors: Mahgoub OM

    更新日期:1987-02-01 00:00:00

  • Efficacy and side effects of flurazepam, fosazepam, and nitrazepam as sleeping aids in psychogeriatric patients.

    abstract::Efficacy and side effects of flurazepam 15 mg, fosazepam 60 mg, and nitrazepam 5 mg were studied in 17 psychogeriatric patients. The drugs were equipotent in maintaining sleep but nitrazepam had more side effects than the other hypnotics, and it induced a rebound insomnia after withdrawal. All hypnotics lost some of t...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1600-0447.1978.tb06871.x

    authors: Viukari M,Linnoila M,Aalto U

    更新日期:1978-01-01 00:00:00

  • Clinical issues in perinatal mental health: new developments in the detection and treatment of perinatal mood and anxiety disorders.

    abstract:OBJECTIVE:This paper presents evidence of new developments in the detection and treatment of perinatal mood and anxiety disorders that have relevance for clinicians. METHOD:An electronic search was conducted in MEDLINE, CINAHL, PsychINFO and The Cochrane Library Database for the interval 1995-2005 for papers published...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.1111/j.1600-0447.2005.00549.x

    authors: Austin MP,Priest SR

    更新日期:2005-08-01 00:00:00

  • Long-term treatment of depression with isocarboxazide.

    abstract::Isocarboxazide has been used as long-term treatment for a selected group of 20 depressive patients, of whom some 90% (17/19) were non-responders to treatment with tricyclic antidepressants. At the follow-up the median duration of illness was 162 months, and the median duration of treatment was 42 months. Side-effects ...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1980.tb00634.x

    authors: Larsen JK,Rafaelsen OJ

    更新日期:1980-11-01 00:00:00

  • Neurocognition in bulimic eating disorders: a systematic review.

    abstract:UNLABELLED:Van den Eynde F, Guillaume S, Broadbent H, Stahl D, Campbell IC, Schmidt U, Tchanturia K. Neurocognition in bulimic eating disorders: a systematic review. OBJECTIVE:  The aim of this study was to review the literature on neurocognition comparing people with a bulimic eating disorder in the acute phase of th...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.1111/j.1600-0447.2011.01701.x

    authors: Van den Eynde F,Guillaume S,Broadbent H,Stahl D,Campbell IC,Schmidt U,Tchanturia K

    更新日期:2011-08-01 00:00:00

  • Suicide attempt predicted by academic performance and childhood IQ: a cohort study of 26 000 children.

    abstract:OBJECTIVE:Academic performance in youth, measured by grade point average (GPA), predicts suicide attempt, but the mechanisms are not known. It has been suggested that general intelligence might underlie the association. METHODS:We followed 26 315 Swedish girls and boys in population-representative cohorts, up to maxim...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/acps.12817

    authors: Sörberg Wallin A,Zeebari Z,Lager A,Gunnell D,Allebeck P,Falkstedt D

    更新日期:2018-04-01 00:00:00

  • Risk factors predicting onset and persistence of subthreshold expression of bipolar psychopathology among youth from the community.

    abstract:OBJECTIVE:To examine factors increasing the risk for onset and persistence of subthreshold mania and depression. METHOD:In a prospective cohort community study, the association between risk factors [a family history of mood disorders, trauma, substance use, attention-deficit/hyperactivity disorder (ADHD) and temperame...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.2010.01539.x

    authors: Tijssen MJ,Van Os J,Wittchen HU,Lieb R,Beesdo K,Wichers M

    更新日期:2010-09-01 00:00:00

  • Peripheral cytokine and chemokine alterations in depression: a meta-analysis of 82 studies.

    abstract:OBJECTIVE:To conduct a systematic review and meta-analysis of studies that measured cytokine and chemokine levels in individuals with major depressive disorder (MDD) compared to healthy controls (HCs). METHOD:The PubMed/MEDLINE, EMBASE, and PsycINFO databases were searched up until May 30, 2016. Effect sizes were esti...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章,meta分析

    doi:10.1111/acps.12698

    authors: Köhler CA,Freitas TH,Maes M,de Andrade NQ,Liu CS,Fernandes BS,Stubbs B,Solmi M,Veronese N,Herrmann N,Raison CL,Miller BJ,Lanctôt KL,Carvalho AF

    更新日期:2017-05-01 00:00:00

  • Agreement in psychiatric assessment.

    abstract::In 103 schizophrenic patients we investigated the extent of practice needed in the use of the Brief Psychiatric Rating Scale (BPRS) to enable its reliability to be assessed. The agreement level of the 7 raters was analysed. Generally, the lowest mean agreement found was for the negative symptoms of the BPRS schizophre...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1993.tb03343.x

    authors: Andersen J,Kørner A,Larsen JK,Schultz V,Nielsen BM,Behnke K,Munk-Andersen E,Bjørum N

    更新日期:1993-02-01 00:00:00

  • Affective disorders among Greenlandic psychiatric patients.

    abstract:OBJECTIVE:The aim of this study was to determine the treatment incidence, diagnostic stability and clinical and social outcome of affective disorders in the Greenlandic population. METHODS:A cohort of Greenlanders first hospitalized in 1980-1983 and diagnosed with an affective disorder at least once during the period ...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1999.tb10892.x

    authors: Lynge I,Munk-Jørgensen P,Mortensen PB

    更新日期:1999-12-01 00:00:00

  • Sleep in the premenstrual phase: a self-report study of PMS patients and normal controls.

    abstract::Sleep disturbances commonly occur in the premenstruum in both Premenstrual Syndrome (PMS) patients and in women from the general population. Reports on the Post-Sleep Inventory were obtained from a clinic sample of PMS patients and samples from the general population dichotomized into a non-clinic group with and witho...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1988.tb06304.x

    authors: Mauri M,Reid RL,MacLean AW

    更新日期:1988-07-01 00:00:00

  • Primary care physicians' and psychiatrists' approaches to treating mild depression.

    abstract:OBJECTIVE:To measure how primary care physicians (PCPs) and psychiatrists treat mild depression. METHOD:We surveyed a national sample of US PCPs and psychiatrists using a vignette of a 52-year-old man with depressive symptoms not meeting Major Depressive Episode criteria. Physicians were asked how likely they were to ...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.2012.01887.x

    authors: Lawrence RE,Rasinski KA,Yoon JD,Meador KG,Koenig HG,Curlin FA

    更新日期:2012-11-01 00:00:00