Preliminary results of a fine-grain analysis of mood swings and treatment modalities of bipolar I and II patients using the daily prospective life-chart-methodology.

Abstract:

OBJECTIVE:The study aimed to increase the knowledge about the detailed course differences between different forms of bipolar disorder. METHOD:Using the prospective life-chart-clinician version, we compared the fine-grain analysis of mood swings and treatment modalities of 18 bipolar II with 31 bipolar I patients. RESULTS:During an observational period of a mean of 26 months we observed an increase of euthymic days, and a decrease of (sub)depressive and (hypo)manic days. Days in a (sub)depressed state were more frequent than days of (hypo)mania as well as days of subdepression or hypomania in comparison to days of full-blown depression or mania. Bipolar II patients showed an increase in hypomanic days receiving more frequently antidepressants. Bipolar I patients, with a decrease of manic days, were significantly taking more often mood stabilizers. CONCLUSION:Treatment in a specialized bipolar clinic improves the overall outcome, but bipolar II disorder seems to be still treated sub-optimally with a possible iatrogenic increase of hypomanic days.

journal_name

Acta Psychiatr Scand

authors

Born C,Seitz NN,Grunze H,Vieta E,Dittmann S,Seemüller F,Amann B

doi

10.1111/j.1600-0447.2009.01412.x

subject

Has Abstract

pub_date

2009-12-01 00:00:00

pages

474-80

issue

6

eissn

0001-690X

issn

1600-0447

pii

ACP1412

journal_volume

120

pub_type

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