Sleep disorders in patients with severe mental depression: double-blind placebo-controlled evaluation of the value of pipamperone (Dipiperon).

Abstract:

:Pipamperone was compared double-blindly with placebo to evaluate its capacity to relieve sleep disorders in 40 depressive inpatients. At the end of the 1-week trial, most of the items relating to sleep disturbances had improved significantly in the 24 patients of the pipamperone group whereas only a few items showed such a change in the control group. On the Hamilton depression scale, improvement in the pipamperone patients was also superior to that in the placebo group as regards the items "depressed mood" and "insight". The adequate median daily dose of pipamperone appeared to be 80 mg (2 tablets).

journal_name

Acta Psychiatr Scand

authors

Ansoms C,Backer-Dierick GD,Vereecken JL

doi

10.1111/j.1600-0447.1977.tb00147.x

subject

Has Abstract

pub_date

1977-02-01 00:00:00

pages

116-22

issue

2

eissn

0001-690X

issn

1600-0447

journal_volume

55

pub_type

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