Association between preeclampsia and attention-deficit hyperactivity disorder: a population-based and sibling-matched cohort study.

Abstract:

OBJECTIVE:To examine the association between preeclampsia and attention-deficit hyperactivity disorder (ADHD), using a large Swedish-based registry cohort. METHODS:This study comprised 2 047 619 children, with 114 934 (5.6%) cases of ADHD. Preeclampsia was based on two alternate definitions: (i) preeclampsia (using ICD-9/ICD-10) and (ii) preeclampsia and small for gestational age (SGA) combined. ADHD was determined in one of two ways: (i) if a diagnosis of ADHD was present in the National Patient Register or (ii) if an individual was in receipt of ADHD medication in the Prescribed Drug Register. Multivariate Cox proportional hazards regression analysis allowed adjustment for several perinatal/sociodemographic factors. Sibling-matched analysis further controlled for shared genetic and familial confounding. RESULTS:In the adjusted Cox model, preeclampsia was associated with an increase in likelihood of ADHD (HR: 1.15, 95% CI: 1.12, 1.19). The HR for preeclampsia and those born SGA was 1.43 (95% CI: 1.31, 1.55) in the adjusted model, compared to those unexposed to preeclampsia/SGA. The sibling-matched analysis did not materially change these associations (HR: 1.13, 95% CI: 1.05, 1.22) and 1.55 (95% CI: 1.28, 1.88). CONCLUSIONS:Exposure to preeclampsia or preeclampsia/SGA was associated with ADHD, independent of genetic/familial factors shared by siblings. However, it is important to note that sibling-matched analysis can only adjust for factors that are constant between pregnancies; therefore, residual confounding cannot be ruled out. Further research is needed to explore modifiable risk factors and identify those most-at-risk babies following delivery.

journal_name

Acta Psychiatr Scand

authors

Maher GM,Dalman C,O'Keeffe GW,Kearney PM,McCarthy FP,Kenny LC,Khashan AS

doi

10.1111/acps.13162

subject

Has Abstract

pub_date

2020-10-01 00:00:00

pages

275-283

issue

4

eissn

0001-690X

issn

1600-0447

journal_volume

142

pub_type

杂志文章
  • Chinese diagnostic interview schedule. II. A validity study on estimation of lifetime prevalence.

    abstract::The validity of DIS-CM (Chinese modified version of Diagnostic Interview Schedule) was examined by analyzing lifetime prevalence of each age group, age at onset, and recency of illness. The magnitude of the discrepancy between the empirical and the estimated data was adopted as the criterion of the degree of deviation...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1986.tb02695.x

    authors: Hwu HG,Yeh EK,Chang LY,Yeh YL

    更新日期:1986-04-01 00:00:00

  • Social cognition in euthymic bipolar disorder: systematic review and meta-analytic approach.

    abstract:OBJECTIVE:Deficits in social cognition have been reported in euthymic subjects with bipolar disorder (BD). However, some studies have failed to find differences favoring controls. As most investigations have been conducted with small samples, they have not had sufficient power to detect statistically significant differ...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/j.1600-0447.2011.01808.x

    authors: Samamé C,Martino DJ,Strejilevich SA

    更新日期:2012-04-01 00:00:00

  • A retrospective study of symptom patterns of cannabis-induced psychosis.

    abstract::The aim of this study was to find out whether there are any similarities between cannabis psychosis on the one hand and schizophrenia and mania on the other, and to delineate any consistency in the pattern of clinical symptoms of cannabis psychosis. Relevant data were collected from patient's case-notes depicting biog...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1991.tb07378.x

    authors: Imade AG,Ebie JC

    更新日期:1991-02-01 00:00:00

  • Impact of substance use on the physical health of patients with bipolar disorder.

    abstract:OBJECTIVE:To describe the impact of tobacco, alcohol and cannabis on metabolic profile and cardiovascular risk in bipolar patients. METHOD:Naturalistic, cross-sectional, multicenter Spanish study. Current use of tobacco, alcohol and cannabis was determined based on patient self-reports. Metabolic syndrome was defined ...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1111/j.1600-0447.2009.01498.x

    authors: Garcia-Portilla MP,Saiz PA,Benabarre A,Florez G,Bascaran MT,Díaz EM,Bousoño M,Bobes J

    更新日期:2010-06-01 00:00:00

  • Effects of child-rearing by schizophrenic mothers: a 25-year follow-up.

    abstract::We conducted a 25-year follow-up study of 50 children of schizophrenic mothers, consisting of 25 children reared by their mothers and 25 children reared apart. The children's adult psychiatric status was evaluated in a 3-h structured interview employing a battery of syndrome check-lists and scales. A slightly higher i...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1997.tb09936.x

    authors: Higgins J,Gore R,Gutkind D,Mednick SA,Parnas J,Schulsinger F,Cannon TD

    更新日期:1997-11-01 00:00:00

  • Platelet MAO activity and personality characteristics. A study in schizophrenic patients and normal individuals.

    abstract::Low levels of platelet monoamine oxidase have been found in schizophrenic and bipolar depressive patients. The enzyme activity seems to correlate negatively with certain personality traits (social activity, sensation seeking, hypomania, positive affect and monotony avoidance) which are correlated to some extent with t...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1981.tb00697.x

    authors: Gattaz WF,Beckmann H

    更新日期:1981-05-01 00:00:00

  • Negative symptoms of schizophrenia and the dexamethasone suppression test.

    abstract::The dexamethasone suppression test (DST) was administered to 30 inpatients who met the DSM-III-R criteria for chronic schizophrenia and shared similar environments. Four of them (13%) were DST nonsuppressors. The mean and maximum postdexamethasone cortisol levels were correlated with the patient's score on the scale f...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1993.tb03485.x

    authors: Garyfallos G,Lavrentiadis G,Amoutzias D,Monas K,Manos N

    更新日期:1993-12-01 00:00:00

  • Attitude of the medical profession to psychiatry.

    abstract::The attitude of the medical profession to psychiatry carries important implications for the quality of personnel attracted into the specialty and for the treatment, in a general medical setting, of patients with mental disorders. This article examines the components of doctors' attitudes and reviews the literature wit...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.1111/j.1600-0447.1992.tb01432.x

    authors: Buchanan A,Bhugra D

    更新日期:1992-01-01 00:00:00

  • Sexual adjustment of male alcoholics.

    abstract::This study set out to describe the sexual attitudes and behaviour of 50 hospitalized alcoholic men by comparing them with a sample of the general population, matched in age and social class. This control sample was identified by random selection from a company register, and subjects were recruited into the study with ...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1978.tb00236.x

    authors: Whalley LJ

    更新日期:1978-10-01 00:00:00

  • Consistent evidence for a biological subtype of depression characterized by low CSF monoamine levels.

    abstract::Analysis of previously published CSF monoamine data has revealed statistical evidence for a biological subtype of depression, characterized by abnormally low CSF-5HIAA and CSF HVA. Using maximum likelihood gaussian mixture analysis we were able to resolve the empirical frequency distributions of both CSF HVA and CSF 5...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1986.tb06219.x

    authors: Gibbons RD,Davis JM

    更新日期:1986-07-01 00:00:00

  • Risk of psychiatric disorders, self-harm behaviour and service use associated with bariatric surgery.

    abstract:OBJECTIVE:To investigate psychiatric outcomes after bariatric surgery, including suicide, self-harm, psychiatric service use and substance misuse. METHOD:Retrospective study on a Danish nationwide register-based cohort of 22 451 patients followed for 1 029 736 person-years. Data were analysed utilizing single- and mul...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/acps.12669

    authors: Kovacs Z,Valentin JB,Nielsen RE

    更新日期:2017-02-01 00:00:00

  • Raised levels of plasma interleukin-1beta in major and postviral depression.

    abstract:OBJECTIVE:Interleukin-1beta (IL-1beta) is released as part of the acute phase immune response and can directly stimulate the release of corticotrophin-releasing hormone and thus induce hypothalamic pituitary adrenal axis hyperactivity. Major depression has been shown to be accompanied by both an acute phase immune resp...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0447.2001.00162.x

    authors: Owen BM,Eccleston D,Ferrier IN,Young AH

    更新日期:2001-03-01 00:00:00

  • Hopelessness and first-episode psychosis: a longitudinal study.

    abstract::Hopelessness has not been adequately studied in first-episode psychotic patients, although it is already present at the early stages, especially in schizophrenic patients. We have studied 96 neuroleptic-naive psychotic patients (49 schizophrenic patients and 47 other non-affective psychotic patients) over a period of ...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1997.tb09900.x

    authors: Aguilar EJ,Haas G,Manzanera FJ,Hernández J,Gracia R,Rodado MJ,Keshavan MS

    更新日期:1997-07-01 00:00:00

  • Adolescent suicide attempts 1973-1982 in the Helsinki area.

    abstract::Four hundred and twenty-two adolescent suicide attempts were examined. The intent to die was weaker than in adult persons. Within lethality no difference was found. Adolescents came mostly from the lowest social classes and their educational status was low. Their mental health was often unsatisfactory. The psychiatric...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1987.tb05617.x

    authors: Kotila L,Lönnqvist J

    更新日期:1987-10-01 00:00:00

  • A survey of the attitudes of chronic psychiatric patients living in the community toward their medication.

    abstract::Because non-compliance with antipsychotic drug therapy is both common and associated with a substantially increased risk of acute relapse, depot medication must be preferred for most schizophrenic out-patients. Yet there is a perception that depot medication is unpopular among patients. In the survey of out-patients r...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1997.tb10133.x

    authors: Pereira S,Pinto R

    更新日期:1997-06-01 00:00:00

  • Religiosity and psychological resilience in patients with schizophrenia and bipolar disorder: an international cross-sectional study.

    abstract:OBJECTIVE:The impact of religious/spiritual activities on clinical outcomes in patients with serious mental illnesses remains controversial, which was addressed in this international cross-sectional study. METHOD:Three-hundred sixty-nine subjects were recruited from Austria (n = 189) and Japan (n = 180), consisting of...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章,多中心研究

    doi:10.1111/acps.12838

    authors: Mizuno Y,Hofer A,Frajo-Apor B,Wartelsteiner F,Kemmler G,Pardeller S,Suzuki T,Mimura M,Fleischhacker WW,Uchida H

    更新日期:2018-04-01 00:00:00

  • Clinical issues in perinatal mental health: new developments in the detection and treatment of perinatal mood and anxiety disorders.

    abstract:OBJECTIVE:This paper presents evidence of new developments in the detection and treatment of perinatal mood and anxiety disorders that have relevance for clinicians. METHOD:An electronic search was conducted in MEDLINE, CINAHL, PsychINFO and The Cochrane Library Database for the interval 1995-2005 for papers published...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.1111/j.1600-0447.2005.00549.x

    authors: Austin MP,Priest SR

    更新日期:2005-08-01 00:00:00

  • Morning light therapy for winter depression: predictors of response.

    abstract::Bright-light therapy is widely regarded as an effective treatment for winter seasonal affective disorder (SAD). We attempted to identify predictors of light therapy response in 54 depressed, drug-free outpatients diagnosed with SAD by DSM-III-R criteria. After a baseline week, patients were treated for 2 weeks with 25...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1994.tb01494.x

    authors: Lam RW

    更新日期:1994-02-01 00:00:00

  • Personality in unipolar and bipolar manic-malancholic patients.

    abstract::By use of standardized case-recording criteria (MULTI-CLAD) manic-melancholic patients were classified as unipolar (n = 13) and bipolar (n = 23). Personality patterns are evaluated when patients were in neutral mood (defined by low symptom rating scale scores). Results showed that the similarities in the personality p...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1980.tb00612.x

    authors: Bech P,Shapiro RW,Sihm F,Nielsen BM,Sørensen B,Rafaelsen OJ

    更新日期:1980-09-01 00:00:00

  • The suicide rate of epilepsy.

    abstract::Evidence from follow-up studies concerned with the mortality of epilepsy suggests the suicide rate is increased. The risk of suicide seems to be higher from temporal lobe epilepsy, for epilepsy with a greater degree of handicap and in the early years of the condition. ...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.1111/j.1600-0447.1987.tb05616.x

    authors: Barraclough BM

    更新日期:1987-10-01 00:00:00

  • Assessment of suicide risk by computer-delivered self-rating questionnaire: preliminary findings.

    abstract::A prospective study of 167 consecutive patients admitted to a general hospital following an episode of deliberate self-harm was carried out; 102 patients were interviewed by computer and then by a psychiatrist who was blind to the results of the computer interview. The computer interview consisted of a self-rating mod...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1989.tb01330.x

    authors: Levine S,Ancill RJ,Roberts AP

    更新日期:1989-09-01 00:00:00

  • Correlates of addiction-related problems in Kuwait: a cross-cultural view.

    abstract::The promise of adopting a valid and reliable tool for diagnosing addiction-related problems is offered by the Addiction Severity Index (ASI). Socially determined admissions and poor treatment facilities may have biased the representativeness of our sample, though methodological difficulties were minimal. The ASI was u...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1988.tb06359.x

    authors: Bilal AM

    更新日期:1988-10-01 00:00:00

  • Prognosis of treated hypochondriasis. A clinical study.

    abstract::Thirty-six patients who had hypochondriacal neurosis for 6 months or longer were treated with individual psychotherapy which focused predominantly on presenting complaints, fears and beliefs. Antianxiety drugs were used at times of anxiety. Sixty-four percent either recovered or improved to the extent that they no lon...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1983.tb06725.x

    authors: Kellner R

    更新日期:1983-02-01 00:00:00

  • Renal function in chronic lithium-treated patients.

    abstract::We investigated the renal function (urine volume, glomerular filtration rate, urinary osmolality and proteinuria) of 50 patients chronically treated with lithium carbonate for major affective disorder. No patient had any alteration in the parameters considered. No relationship was found between any of the parameters s...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1989.tb10295.x

    authors: Conte G,Vazzola A,Sacchetti E

    更新日期:1989-05-01 00:00:00

  • Clinical and neurocognitive correlates of insight in patients with bipolar I disorder in remission.

    abstract:OBJECTIVE:The relationship between insight and neurocognition in bipolar disorder has not been clearly established. METHOD:A neuropsychological battery assessing attention, mental control, perceptual-motor skills, executive functions, verbal fluency and abstraction, and visuo-spatial attention was administered to 50 b...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.2007.01110.x

    authors: Dias VV,Brissos S,Carita AI

    更新日期:2008-01-01 00:00:00

  • Involuntary treatment of schizophrenia patients 2004-2010 in Denmark.

    abstract:OBJECTIVE:Treatment of schizophrenia is frequently complicated by patients' ambivalence and lack of insight into the disease, occasionally warranting involuntary treatment. This study aims to describe involuntary treatment in Danish schizophrenia patients. METHOD:Patients diagnosed with a lifetime ICD-10 F20 schizophr...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/acps.12144

    authors: Andersen TH,Kappers D,Sneider B,Uggerby P,Nielsen J

    更新日期:2014-04-01 00:00:00

  • Cannabis use in early adulthood is prospectively associated with prescriptions of antipsychotics, mood stabilizers, and antidepressants.

    abstract:OBJECTIVE:Cannabis is an acknowledged risk factor for some mental disorders, but for others the evidence is inconclusive. Prescribed medicinal drugs can be used as proxies for mental disorders. In this study, we investigate how use of cannabis is prospectively related to prescription of antipsychotics, mood stabilizers...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/acps.13104

    authors: Rognli EB,Bramness JG,von Soest T

    更新日期:2020-02-01 00:00:00

  • Early identification of bipolar disorder among young adults - a 22-year community birth cohort.

    abstract:OBJECTIVE:We set forth to build a prediction model of individuals who would develop bipolar disorder (BD) using machine learning techniques in a large birth cohort. METHODS:A total of 3748 subjects were studied at birth, 11, 15, 18, and 22 years of age in a community birth cohort. We used the elastic net algorithm wit...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/acps.13233

    authors: Rabelo-da-Ponte FD,Feiten JG,Mwangi B,Barros FC,Wehrmeister FC,Menezes AM,Kapczinski F,Passos IC,Kunz M

    更新日期:2020-12-01 00:00:00

  • Hallucinations in patients with borderline personality disorder: characteristics, severity, and relationship with schizotypy and loneliness.

    abstract:OBJECTIVE:In patients with borderline personality disorder (BPD), data are lacking on characteristics and severity of hallucinations in modalities other than the auditory (verbal) type. The same applies to relationships between hallucinations and the severity of depression, anxiety, schizotypy, and loneliness. METHODS...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/acps.13012

    authors: Slotema CW,Bayrak H,Linszen MMJ,Deen M,Sommer IEC

    更新日期:2019-05-01 00:00:00

  • Adjustment reactions: a long-term prospective and retrospective follow-up of former patients in a crisis intervention ward.

    abstract::The results of a 5-year follow-up study of 76 patients in a crisis intervention ward who were suffering from an adjustment reaction (brief or prolonged depressive reaction) according to ICD-9 criteria indicate a rather favorable course and outcome using standardized instruments. Only 17% developed a chronic or severe ...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1991.tb01426.x

    authors: Bronisch T

    更新日期:1991-07-01 00:00:00