Impact of substance use on the physical health of patients with bipolar disorder.

Abstract:

OBJECTIVE:To describe the impact of tobacco, alcohol and cannabis on metabolic profile and cardiovascular risk in bipolar patients. METHOD:Naturalistic, cross-sectional, multicenter Spanish study. Current use of tobacco, alcohol and cannabis was determined based on patient self-reports. Metabolic syndrome was defined using the National Health and Nutrition Examination Survey 1999-2000 and the American Heart Association/National Heart, Lung and Blood Institute criteria, and cardiovascular risk using the Framingham and the Systematic Coronary Risk Evaluation functions. RESULTS:Mean age was 46.6 years, 49% were male. Substance use: 51% tobacco, 13% alcohol and 12.5% cannabis. Patients who reported consuming any substance were significantly younger and a higher proportion was male. After controlling for confounding factors, tobacco was a risk factor for coronary heart disease (CHD) (unstandardized linear regression coefficient 3.47, 95% confidence interval 1.85-5.10). CONCLUSION:Substance use, mainly tobacco, was common in bipolar patients. Tobacco use negatively impacted CHD risk.

journal_name

Acta Psychiatr Scand

authors

Garcia-Portilla MP,Saiz PA,Benabarre A,Florez G,Bascaran MT,Díaz EM,Bousoño M,Bobes J

doi

10.1111/j.1600-0447.2009.01498.x

subject

Has Abstract

pub_date

2010-06-01 00:00:00

pages

437-45

issue

6

eissn

0001-690X

issn

1600-0447

pii

ACP1498

journal_volume

121

pub_type

临床试验,杂志文章,多中心研究
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