Negative symptoms of schizophrenia and the dexamethasone suppression test.

Abstract:

:The dexamethasone suppression test (DST) was administered to 30 inpatients who met the DSM-III-R criteria for chronic schizophrenia and shared similar environments. Four of them (13%) were DST nonsuppressors. The mean and maximum postdexamethasone cortisol levels were correlated with the patient's score on the scale for the Schedule for the Assessment of Negative Symptoms and with the score on the anergia subscale of the Brief Psychiatric Rating Scale. None of the correlations were statistically significant. Furthermore, the scores on the above scales were not significantly correlated with clinical variables such as duration of illness, number of admissions or length of hospitalization, nor were any significant correlations found between the postdexamethasone cortisol levels and the score on the Beck Depression Inventory. In addition, depressed and nondepressed schizophrenics did not differ regarding the rate of nonsuppression and the postdexamethasone cortisol levels. This study found that: 1) dexamethasone nonsuppression in schizophrenia was not related to the presence of negative symptoms; 2) there was no relationship between negative symptoms and illness variables; and 3) the depressed schizophrenics did not display increased nonsuppression compared with nondepressed schizophrenics.

journal_name

Acta Psychiatr Scand

authors

Garyfallos G,Lavrentiadis G,Amoutzias D,Monas K,Manos N

doi

10.1111/j.1600-0447.1993.tb03485.x

subject

Has Abstract

pub_date

1993-12-01 00:00:00

pages

425-8

issue

6

eissn

0001-690X

issn

1600-0447

journal_volume

88

pub_type

杂志文章
  • Service use and costs of people with dual diagnosis in South London.

    abstract:OBJECTIVE:To compare the service use and costs of individuals who have a dual diagnosis of psychosis and substance abuse with those who have a diagnosis of psychosis but no substance abuse. METHOD:Patients with psychosis were identified and a representative sample were interviewed. Six-month service use was measured a...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0447.2000.101006464.x

    authors: McCrone P,Menezes PR,Johnson S,Scott H,Thornicroft G,Marshall J,Bebbington P,Kuipers E

    更新日期:2000-06-01 00:00:00

  • Service utilization and costs of first-onset schizophrenia in two widely differing health service areas in North-East Spain. PSICOST Group.

    abstract:OBJECTIVE:The aim of the study was to analyse the cost-incidence of schizophrenia in two areas with widely differing health service systems. METHOD:The costs of patients with schizophrenia in the 3 years after the first service contact were evaluated (i) in an area (A) with fully developed mental health community prog...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1999.tb10876.x

    authors: Salvador-Carulla L,Haro JM,Cabasés J,Madoz V,Sacristán JA,Vázquez-Barquero JL

    更新日期:1999-11-01 00:00:00

  • Labour force activity by people with depression and anxiety disorders: a population-level second-order analysis.

    abstract:OBJECTIVE:To identify the population-level first- and second-order effects among candidate correlates of labour force activity by people with ICD-10 depression and anxiety disorders. METHOD:Australian Bureau of Statistics multistage sampling strategies obtained a household sample of 37,580 individuals. Analyses were c...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.2005.00600.x

    authors: Waghorn G,Chant D

    更新日期:2005-12-01 00:00:00

  • Does hallucination perceptual modality impact psychosis risk?

    abstract:OBJECTIVE:Subthreshold perceptual abnormalities are commonly used to identify individuals at clinical high risk (CHR) for developing a psychotic disorder. Predictive validity for modality-specific perceptual abnormality severity on psychosis risk is unknown. METHODS:We examined prospectively collected data from 164 in...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/acps.13078

    authors: Niles HF,Walsh BC,Woods SW,Powers AR 3rd

    更新日期:2019-10-01 00:00:00

  • The distinction of bipolar II disorder from bipolar I and recurrent unipolar depression: results of a controlled family study.

    abstract::The aim of the study was to differentiate bipolar II, bipolar I and recurrent unipolar depression by their familial load for affective disorders. Eighty bipolar, 108 unipolar, 80 control subjects and interviewed first-degree relatives were diagnosed according to Research Diagnostic Criteria using the Schedule for Affe...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1993.tb03372.x

    authors: Heun R,Maier W

    更新日期:1993-04-01 00:00:00

  • Mental disorders in first-degree relatives of schizophrenics.

    abstract::A total 215 first-degree relatives of 88 twin probands with schizophrenia, mood disorders and nonaffective psychoses were studied. The twins' parents and siblings were personally interviewed with structured diagnostic instruments and diagnosed in accordance with DSM-III-R criteria. The first-degree relatives were inte...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1991.tb05577.x

    authors: Onstad S,Skre I,Edvardsen J,Torgersen S,Kringlen E

    更新日期:1991-06-01 00:00:00

  • Early behavioral symptoms and course of Alzheimer's disease.

    abstract:OBJECTIVE:To determine if behavioral symptoms detected at initial evaluation relate to cognitive or functional status or survival time in Alzheimer's disease (AD) patients. method: Review, in 100 cases of autopsy-proven AD, of the relationship of behavioral symptoms detected at initial evaluation to cognitive and globa...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.1111/j.1600-0447.2004.00472.x

    authors: Weiner MF,Hynan LS,Bret ME,White C 3rd

    更新日期:2005-05-01 00:00:00

  • Identifying crime victims who are at high risk for post traumatic stress disorder: developing a practical referral instrument.

    abstract:OBJECTIVE:To construct a practical instrument for the identification and referral of crime victims who are at high risk for post traumatic stress disorder (PTSD). METHOD:Crime victims filing a complaint at a police station were asked to fill out a questionnaire probing risk factors for PTSD (n=126). One and 3 months l...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0447.2002.01099.x

    authors: Wohlfarth T,Winkel FW,Van Den Brink W

    更新日期:2002-06-01 00:00:00

  • Electrodermal and heart-rate measurements in chronic and partially remitted schizophrenic patients.

    abstract::Electrodermal activity and heart-rate were recorded in the laboratory from partially remitted schizophrenic patients living in the community, chronic schizophrenic inpatients and normal controls. Althoug all patients had faster heart-rates, no consistent electrodermal differences between patient groups and normals wer...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1978.tb06905.x

    authors: Tarrier N,Cooke EC,Lader MH

    更新日期:1978-05-01 00:00:00

  • Co-occurrence of Axis I and Axis II disorders in substance abusers.

    abstract:OBJECTIVE:This study examined the co-occurrence of anxiety/mood and personality disorders (PDs) in substance abusers, the impact of anxiety/ mood disorders on the symptom profiles of PDs, and the impact of anxiety/mood disorders and PDs on pre-treatment status. METHOD:Current anxiety/mood disorders and PDs and pre-tre...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0447.2000.90050.x

    authors: Verheul R,Kranzler HR,Poling J,Tennen H,Ball S,Rounsaville BJ

    更新日期:2000-02-01 00:00:00

  • Cognitive functioning and survival in psychogeriatric patients.

    abstract::The relationship between cognitive functioning and survival was studied among 92 people referred to a psychogeriatric assessment unit. A follow-up 4-5 years later showed that the nonsurvivors initially had lower scores on the Mini-Mental State Examination (MMSE) than the survivors. The differences were greatest among ...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1991.tb03121.x

    authors: Berg S,Jeppson L

    更新日期:1991-08-01 00:00:00

  • A repetition-prediction study of European parasuicide populations: a summary of the first report from part II of the WHO/EURO Multicentre Study on Parasuicide in co-operation with the EC concerted action on attempted suicide.

    abstract::One of the aims of the European Study on Parasuicide, which was initiated by the Regional Office for the European Region of the World Health Organization in the mid-1980s, was to try to identify social and personal characteristics that are predictive of future suicidal behaviour. A follow-up interview study (the Repet...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章,多中心研究

    doi:10.1111/j.1600-0447.1997.tb00378.x

    authors: Bille-Brahe U,Kerkhof A,De Leo D,Schmidtke A,Crepet P,Lonnqvist J,Michel K,Salander-Renberg E,Stiles TC,Wasserman D,Aagaard B,Egebo H,Jensen B

    更新日期:1997-02-01 00:00:00

  • Interhemispheric electroencephalographic coherence as a biological marker in alcoholism.

    abstract::Electroencephalographic coherence scores in 21 teetotaler first-degree relatives of alcoholics, 27 subjects with alcohol dependence and 21 healthy subjects without a family history of alcohol abuse were compared. The relatives had significantly higher coherence scores in the frontal and parietal leads than the alcohol...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1993.tb03358.x

    authors: Michael A,Mirza KA,Mukundan CR,Channabasavanna SM

    更新日期:1993-03-01 00:00:00

  • Deep venous thrombosis and pulmonary embolism following physical restraint.

    abstract:OBJECTIVE:We describe a case of deep venous thrombosis (DVT) and pulmonary embolism (PE) following the use of physical restraint in a patient with a diagnosis of acute delusional psychotic disorder. METHOD:A new case report of DVT and PE associated with prolonged physical restraint is presented. The literature on phys...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.2004.00456.x

    authors: Laursen SB,Jensen TN,Bolwig T,Olsen NV

    更新日期:2005-04-01 00:00:00

  • Interviews with psychiatric inpatients about professional intervention with regard to their children.

    abstract::A description of mentally ill parents' experience and points of view concerning professional intervention in relation to their young children is presented in this paper. The results are from an interview survey designed with the purpose of improving the basis for cooperation between mentally ill patients and professio...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1996.tb10619.x

    authors: Wang AR,Goldschmidt VV

    更新日期:1996-01-01 00:00:00

  • How to treat mania.

    abstract:OBJECTIVE:In this paper, we aimed at reviewing evidence-based treatment options for bipolar mania and proposed tentative evidence-based clinical suggestions regarding the management of a manic episode, especially regarding the choice of the proper mood stabilizer and antipsychotic medication. METHOD:A narrative review...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/acps.13209

    authors: Pacchiarotti I,Anmella G,Colomer L,Vieta E

    更新日期:2020-09-01 00:00:00

  • A repeated dose comparison of three benzodiazepine derivative (nitrazepam, flurazepam and flunitrazepam) on subjective appraisals of sleep and measures of psychomotor performance the morning following night-time medication.

    abstract::Repeated doses of 5 mg nitrazepam, 15 mg flurazepam, and 1 mg flunitrazepam improved subjective assessments of the ease of getting to sleep and the perceived quality of induced sleep in a population of 30 healthy volunteers. The subjective reports of improved sleep inducement were related to a perceived difficulty in ...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1600-0447.1977.tb06678.x

    authors: Hindmarch I

    更新日期:1977-11-01 00:00:00

  • Psychiatric disorder in children with birth anomalies. A retrospective follow-up study.

    abstract::A group of 273 children and adolescents, aged 8 to 19 years, who had been treated for a congenital malformation during their 1st month of life, were studied using psychiatric interviews with the child and at least one of his parents. The child was also given a Wechsler intelligence test. The rate of psychopathological...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1976.tb00089.x

    authors: Sandberg S

    更新日期:1976-07-01 00:00:00

  • Adrenocorticotropin and cortisol response to lysine vasopressin in relation to the outcome of the dexamethasone suppression test in major depressive disorder.

    abstract::The pathophysiology behind the abnormalities of the hypothalamic pituitary adrenal cortex axis found in patients with major depressive disorder was studied by the use of the vasopressin test. The response of plasma adrenocorticotropin (ACTH) and cortisol to the injection of 10 IU lysine-vasopressin (LVP) was investiga...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1988.tb05142.x

    authors: Akner G,Ljunggren JG,Kjellman BF,Undén F,Wetterberg L

    更新日期:1988-04-01 00:00:00

  • Preventing breast cancer in women with schizophrenia.

    abstract:OBJECTIVE:To record risk factors for breast cancer in women with schizophrenia and recommend preventive actions. METHOD:A PubMed literature search (from 2005 to 2010) was conducted, using the search terms 'schizophrenia', 'antipsychotics', 'breast cancer' and 'risk factors'. RESULTS:Several risk factors of relevance ...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.2010.01626.x

    authors: Seeman MV

    更新日期:2011-02-01 00:00:00

  • Psychodynamic personality profile in first-episode severe mental disorders.

    abstract:OBJECTIVE:The aim of this study was to relate measures of psychoanalytically derived personality traits to descriptive diagnosis and psychopathology in severe mental disorders. METHOD:Sixty-one consecutive first-episode patients with schizophrenia, bipolar disorder and severe major depression were interviewed. Persona...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.2003.00289.x

    authors: Heikkilä J,Karlsson H,Taiminen T,Lauerma H,Ilonen T,Leinonen KM,Wallenius E,Virtanen H,Heinimaa M,Kaljonen A,Salokangas RK

    更新日期:2004-03-01 00:00:00

  • Changes in public attitudes towards mental illness in the Athens area (1979/1980-1994).

    abstract::Opinions about mental illness were measured, in 1994, in a probability sample consisting of 360 residents of two boroughs in greater Athens. These boroughs represent the catchment area of a community mental health centre. The aim of this study was to compare the differences in attitudes towards mental illness with a m...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1999.tb05387.x

    authors: Madianos MG,Economou M,Hatjiandreou M,Papageorgiou A,Rogakou E

    更新日期:1999-01-01 00:00:00

  • Hallucinations in patients with borderline personality disorder: characteristics, severity, and relationship with schizotypy and loneliness.

    abstract:OBJECTIVE:In patients with borderline personality disorder (BPD), data are lacking on characteristics and severity of hallucinations in modalities other than the auditory (verbal) type. The same applies to relationships between hallucinations and the severity of depression, anxiety, schizotypy, and loneliness. METHODS...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/acps.13012

    authors: Slotema CW,Bayrak H,Linszen MMJ,Deen M,Sommer IEC

    更新日期:2019-05-01 00:00:00

  • A double-blind randomized placebo-controlled study of the efficacy and safety of pirlindole, a reversible monoamine oxidase A inhibitor, in the treatment of depression.

    abstract::The efficacy and safety of pirlindole (300 mg/day), a new reversible inhibitor of monoamine oxidase A, have been evaluated in a multicentre placebo-controlled double-blind randomized trial in 103 in-patients suffering from unipolar major depression (DSM-III-R 296.2, 296.3) over a 42-day period after a run-in placebo p...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1111/j.1600-0447.1996.tb09881.x

    authors: De Wilde JE,Geerts S,Van Dorpe J,Bruhwyler J,Géczy J

    更新日期:1996-12-01 00:00:00

  • Acoustic analysis of speech variables during depression and after improvement.

    abstract::Speech recordings were made of 16 depressed patients during depression and after clinical improvement. The recordings were analyzed using a computer program which extracts acoustic parameters from the fundamental frequency contour of the voice. The percent pause time, the standard deviation of the voice fundamental fr...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1987.tb02891.x

    authors: Nilsonne A

    更新日期:1987-09-01 00:00:00

  • Rediscovering chronic mania.

    abstract:OBJECTIVE:This paper presents a case of chronic mania and reviews the diagnosis with respect to its definition and utility. METHOD:A case of chronic mania is described. RESULTS:Unremitting mania poses a diagnostic and management challenge. CONCLUSION:Persistent mania of this duration is rare, but a diagnosis of chro...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0447.2001.00289.x

    authors: Malhi GS,Mitchell PB,Parker GB

    更新日期:2001-08-01 00:00:00

  • Comparison of participants and nonparticipants in a neuroendocrine investigation of psychosis.

    abstract::Of all neuroleptic-naive, acutely psychotic subjects admitted to hospital over a 2-year period (n = 62), 27 participated in a neuroendocrine study and 35 did not participate (51% refused consent, 19% were incapable of consent and 31% started neuroleptics immediately). However, all nonparticipants agreed to psychopatho...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1991.tb05558.x

    authors: Keks NA,Copolov DL,Mackie B,Stuart GW,Singh BS,McGorry PD,Coffey C

    更新日期:1991-05-01 00:00:00

  • Affective disorders among Greenlandic psychiatric patients.

    abstract:OBJECTIVE:The aim of this study was to determine the treatment incidence, diagnostic stability and clinical and social outcome of affective disorders in the Greenlandic population. METHODS:A cohort of Greenlanders first hospitalized in 1980-1983 and diagnosed with an affective disorder at least once during the period ...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1999.tb10892.x

    authors: Lynge I,Munk-Jørgensen P,Mortensen PB

    更新日期:1999-12-01 00:00:00

  • Bright light therapy of subsyndromal seasonal affective disorder in the workplace: morning vs. afternoon exposure.

    abstract:OBJECTIVE:Bright light therapy in seasonal affective disorder (SAD) has been studied extensively. However, little attention has been given to subsyndromal seasonal affective disorder (SSAD) or the use of bright light in the workplace. Many patients using bright light boxes complain of the inconvenience of use. Much of ...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 临床试验,杂志文章

    doi:10.1034/j.1600-0447.2001.00078.x

    authors: Avery DH,Kizer D,Bolte MA,Hellekson C

    更新日期:2001-04-01 00:00:00

  • The Reactivity of Psychosis Rating Form (RPRF): background, development and psychometrics.

    abstract::The ICD-10 and DSM-IV classifications have both given low priority to "reactivity" to acute stress as a classificatory principle for functional psychoses. In Scandinavia, reactivity is still considered an important factor in the development of such psychoses. Reactivity is a complex concept, and its various components...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章,多中心研究

    doi:10.1111/j.1600-0447.1996.tb09811.x

    authors: Guldberg CA,Dahl AA,Bertelsen A,Hansen H,Haslerud J,Hytten K,Narud K

    更新日期:1996-02-01 00:00:00