Abstract：
:A total 215 first-degree relatives of 88 twin probands with schizophrenia, mood disorders and nonaffective psychoses were studied. The twins' parents and siblings were personally interviewed with structured diagnostic instruments and diagnosed in accordance with DSM-III-R criteria. The first-degree relatives were interviewed by interviewers who were blind to the twins' diagnoses. Schizophrenia and schizotypal personality disorder were significantly more frequent in first-degree relatives of schizophrenic twins. Respectively, anxiety and mood disorders were significantly more prevalent among the parents and siblings of probands with mood disorders. Schizophrenic spectrum disorders were significantly more common in the families of schizophrenic probands compared with relatives of mood disorder probands, thus confirming a relationship between schizophrenia and schizophrenic spectrum disorders. However, we cannot, based on our study, specify whether this relationship is caused by genetic or environmental factors.
journal_name
Acta Psychiatr Scandjournal_title
Acta psychiatrica Scandinavicaauthors
Onstad S,Skre I,Edvardsen J,Torgersen S,Kringlen Edoi
10.1111/j.1600-0447.1991.tb05577.xsubject
Has Abstractpub_date
1991-06-01 00:00:00pages
463-7issue
6eissn
0001-690Xissn
1600-0447journal_volume
83pub_type
杂志文章abstract：:Previous research in neuroendocrinology has evidenced that hyperactivity of the hypothalamic-pituitary-adrenal axis (HPA) depends on hypersecretion of corticotropin-releasing hormone (CRH). The aim of this study was to investigate the activity of HPA before and after recovery in depressed patients treated with electro...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1990.tb03053.x
更新日期：1990-09-01 00:00:00
abstract：:In a study of psychotherapy in schizophrenic patients, the existence of certain clinical and anamnestic variables, such as persistent auditory hallucinations, was found to correlate with a negative outcome. To test whether these clinical variables could be a sign of organic brain abnormality, the records of 33 schizop...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1992.tb03299.x
更新日期：1992-12-01 00:00:00
abstract：:Emergency Psychiatric Service of the Department of Psychiatry at the University of Athens is the only referral service for the emergency psychiatric cases coming from the Athens greater area. During 1981 2,169 patients used the Service. The relations of socio-demographic and resource factors of the 26 districts of the...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1987.tb02758.x
更新日期：1987-01-01 00:00:00
abstract：OBJECTIVE:There is ongoing concern about the possible negative impact of ECT on neurocognitive functioning in older patients. In this study, we aimed to characterize the long-term cognitive effects of ECT in patients with late-life depression, using an extensive neuropsychological battery. METHODS:A total of 110 patie...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/acps.12942
更新日期：2018-09-01 00:00:00
abstract：:Eleven children who had received a diagnosis of elective mutism upon admission to the children's psychiatric clinic, were followed up 8--18 years later. The average age upon admission was 9 1/2 years, and at the time of follow-up, 23 years. Nine of the children came from homes with a strong familial shyness and reserv...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1979.tb06962.x
更新日期：1979-02-01 00:00:00
abstract：:A prospective study of 167 consecutive patients admitted to a general hospital following an episode of deliberate self-harm was carried out; 102 patients were interviewed by computer and then by a psychiatrist who was blind to the results of the computer interview. The computer interview consisted of a self-rating mod...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1989.tb01330.x
更新日期：1989-09-01 00:00:00
abstract：OBJECTIVE:Most rating scales for bipolar disorders (BDs) do not encompass the spectrum of symptomatology now established as characterizing the illness. We report the rationale, format, reliability and initial validity studies of the Bipolar Inventory of Symptoms Scale (BISS), a 44-item scale designed to encompass the s...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.2006.00955.x
更新日期：2007-09-01 00:00:00
abstract：:A 'short family therapy' in schizophrenia, according to a specific systemic model (the 'Elementary Pragmatic Model' or EPM) with a strong paradoxical structure is presented. A total of 38 schizophrenic patients, randomly allocated, were treated according to the EPM model combined with psychotropic drugs (19 cases, eac...
journal_title：Acta psychiatrica Scandinavica
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1111/j.1600-0447.1997.tb09618.x
更新日期：1997-03-01 00:00:00
abstract：:Our clinical experience that lithium is an agent used infrequently for self-poisoning was investigated. The rate at which such overdoses occurred was determined from hospital records. A retrospective case notes study then compared overdose rates in patients taking lithium versus patients on antidepressant medication. ...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1994.tb01555.x
更新日期：1994-07-01 00:00:00
abstract：:Little attention has been payed to the classification of psychotic symptoms in dementia sufferers. This article compares the etiology of delusions, visual hallucinations and delusional misidentification and examines the value of factors generated from principal components analysis as a possible classificatory system i...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1995.tb09544.x
更新日期：1995-07-01 00:00:00
abstract：OBJECTIVE:To determine whether a 24-week, needs-based cognitive-behaviourally oriented family intervention for patients suffering from schizophrenia led to improved relapse profiles over a 5-year follow-up period. METHOD:The case notes of 60 patients who had participated in a randomized, controlled effectiveness trial...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1600-0447.2007.01097.x
更新日期：2007-12-01 00:00:00
abstract：:alpha 1 antitrypsin deficiency (ATD) predisposes the individual for serious lung disease in adulthood. The identification of ATD by neonatal screening was hypothesized to have negative long-term effects on the parents' attitudes and feelings associated with the child. This hypothesis was tested by comparing these atti...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1986.tb06252.x
更新日期：1986-10-01 00:00:00
abstract：OBJECTIVE:This study examined the predictors, extent and pattern of fatal antidepressant overdose (FAO) in all psychoactive drug-related deaths and compared these in drug abusers and non-drug abusers. METHOD:Inquest data on 491 psychoactive drug-related cases in England and Wales were analysed. We examined predictors ...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1034/j.1600-0447.2000.102004295.x
更新日期：2000-10-01 00:00:00
abstract：BACKGROUND:The COVID-19 pandemic in Ireland resulted in a nationwide quarantine on March 27, 2020. This study represents the first assessment of rates of anxiety and depression in the general population of Ireland during the pandemic. AIMS:Our first aim was to estimate the probable prevalence rates of generalized anxi...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/acps.13219
更新日期：2020-09-01 00:00:00
abstract：OBJECTIVE:Lifetime and 12-month prevalence of traumatic events and DSM-IV post-traumatic stress disorder as well as risk factors and comorbidity patterns were investigated in a representative community sample (n = 3021, aged 14-24 years). METHOD:Traumatic events and PTSD were assessed with the Munich Composite Interna...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1034/j.1600-0447.2000.101001046.x
更新日期：2000-01-01 00:00:00
abstract：:The relationship between the family variables of expressed emotion (EE) and communication deviance (CD) and patient attributes of cognitive functions and clinical symptoms were examined. Eleven schizophrenic patients and their parents were evaluated at the beginning and the end of a 2-year treatment programme. The tes...
journal_title：Acta psychiatrica Scandinavica
pub_type： 临床试验,杂志文章
doi：10.1111/j.1600-0447.1994.tb01569.x
更新日期：1994-08-01 00:00:00
abstract：:Case notes of patients from nine different cultural groups admitted to a London hospital were scrutinized for religious background and religious phenomenology. With the exception of preaching behaviour there were no statistically significant cultural differences, but certain trends were apparent. The pattern of religi...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1985.tb02571.x
更新日期：1985-07-01 00:00:00
abstract：:Trends in death rates from all suicides and specific methods of suicide in Italy over the period 1955-79 were analysed on the basis of age-specific and age-standardised rates, and through a log-linear Poisson model to isolate the effects of age, birth cohort and calendar period. In both sexes, a large decrease in mort...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1986.tb10597.x
更新日期：1986-08-01 00:00:00
abstract：OBJECTIVE:This paper presents a case of chronic mania and reviews the diagnosis with respect to its definition and utility. METHOD:A case of chronic mania is described. RESULTS:Unremitting mania poses a diagnostic and management challenge. CONCLUSION:Persistent mania of this duration is rare, but a diagnosis of chro...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1034/j.1600-0447.2001.00289.x
更新日期：2001-08-01 00:00:00
abstract：:Clonazepam (CLN), a benzodiazepine originally used as an anti-epileptic, was tested in schizophrenia in a double blind comparison in combination with haloperidol (HL). Twenty-four schizophrenic inpatients, diagnosed according to DSM III were treated with HL and CLN (Group 1) or HL and placebo (Group 2) for 4 weeks. Th...
journal_title：Acta psychiatrica Scandinavica
pub_type： 临床试验,杂志文章
doi：10.1111/j.1600-0447.1987.tb02942.x
更新日期：1987-12-01 00:00:00
abstract：:To evaluate the question of whether "mixed" bipolar disorder is a distinct entity, we compared selected cerebrospinal fluid (CSF) biochemical parameters from patients with bipolar disorder, mixed, to those with mania and major depression. Fourteen patients in each category (DSM-III) were studied with regard to CSF HVA...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1988.tb06339.x
更新日期：1988-09-01 00:00:00
abstract：:Analysis of previously published CSF monoamine data has revealed statistical evidence for a biological subtype of depression, characterized by abnormally low CSF-5HIAA and CSF HVA. Using maximum likelihood gaussian mixture analysis we were able to resolve the empirical frequency distributions of both CSF HVA and CSF 5...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1986.tb06219.x
更新日期：1986-07-01 00:00:00
abstract：:Cerebrospinal fluid levels of radioreceptor assayable insulin-like growth factors (RRA-IGFs) and immunoreactive somatomedin B (SMB) (RIA-B) were determined in apparently healthy individuals and in patients with dementia of the Alzheimer type (AD). The CSF levels of RIA-B and RRA-IGFs did not alter from the healthy con...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1988.tb05193.x
更新日期：1988-06-01 00:00:00
abstract：:This article examines admission rates for schizophrenia in terms of degree of urbanization. Patient data was obtained from the Dutch psychiatric register. The scale of urbanization used had five categories and was utilized to establish the degree of urbanization in each municipality (n=647). Admission rates showed a s...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1997.tb10167.x
更新日期：1997-10-01 00:00:00
abstract：OBJECTIVE:Patients who engage in recurrent deliberate self-harm (DSH) behaviours have increased morbidity and mortality and use emergency services more than others. Unrecognized iatrogenic injury may play a role. Specifically, we call attention to the potential danger of cumulative radiation exposure. METHOD:Case pres...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.2010.01538.x
更新日期：2010-11-01 00:00:00
abstract：:A representative selection of 2,283 persons, 18-65 years old in "former" Stockholm County were examined by psychiatrists in 1970-71. The total non-response was 12%. The 12-month prevalence of mental disorders in relation to social class (I-III), marital status and immigration was estimated. The "psychiatric diagnoses ...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1985.tb01262.x
更新日期：1985-02-01 00:00:00
abstract：OBJECTIVE:Serving military can be regarded as exposure to a moderate enforced stressor independent of other vulnerability factors. The aims of this study were i) to explore psychiatric morbidity and mortality during 10 years of follow-up in a cohort of healthy adolescent Danish conscripts and ii) to investigate whether...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.2007.01129.x
更新日期：2008-02-01 00:00:00
abstract：BACKGROUND:Early diagnosis is important for the course of schizophrenia. AIM:To investigate whether prodromal symptoms of schizophrenia lead to increased use of primary care. METHOD:A register-based cohort study of 21 894 cases with incident schizophrenia and 437 880 matched controls. RESULTS:Cases used daytime prim...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/acps.12600
更新日期：2016-09-01 00:00:00
abstract：:Time trends for suicide, homicide and accident mortality among the Finnish population 65 years or over in 1951-1979 are presented. From 1951 to 1967 suicide, motor-vehicle accident mortality and overall accident mortality among elderly males tended to follow more or less similar patterns. In 1951-1979 male suicide rat...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1985.tb02588.x
更新日期：1985-08-01 00:00:00
abstract：:A mild form of neuroleptic malignant syndrome (NMS) in a schizophrenic patient who was receiving a depot neuroleptic is described and beneficial response to oral diazepam 50 mg daily is reported. ...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1988.tb06355.x
更新日期：1988-09-01 00:00:00
