Persistent auditory hallucinations correlate with the size of the third ventricle in schizophrenic patients.

Abstract:

:In a study of psychotherapy in schizophrenic patients, the existence of certain clinical and anamnestic variables, such as persistent auditory hallucinations, was found to correlate with a negative outcome. To test whether these clinical variables could be a sign of organic brain abnormality, the records of 33 schizophrenic patients who had been examined by computerized tomography (CT) were investigated regarding the occurrence of these symptoms. A significant correlation was found between width of the third ventricle and the occurrence of such auditory hallucinations, which also persisted between acute phases. No correlation was found between the CT measures and other clinical characteristics, including hallucinations rated at admission by the Comprehensive Psychopathological Rating Scale (CPRS). The results are interpreted to suggest a disturbance of diencephalic brain regions in a subgroup of schizophrenic patients that are further characterized by persistent auditory hallucinations and a lack of response to psychodynamic psychotherapy.

journal_name

Acta Psychiatr Scand

authors

Cullberg J,Nybäck H

doi

10.1111/j.1600-0447.1992.tb03299.x

subject

Has Abstract

pub_date

1992-12-01 00:00:00

pages

469-72

issue

6

eissn

0001-690X

issn

1600-0447

journal_volume

86

pub_type

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