The distinction of bipolar II disorder from bipolar I and recurrent unipolar depression: results of a controlled family study.

Abstract:

:The aim of the study was to differentiate bipolar II, bipolar I and recurrent unipolar depression by their familial load for affective disorders. Eighty bipolar, 108 unipolar, 80 control subjects and interviewed first-degree relatives were diagnosed according to Research Diagnostic Criteria using the Schedule for Affective Disorders and Schizophrenia--lifetime version. The morbid risks for bipolar I disorder were equivalent in relatives of bipolar I (3.6%) and bipolar II (3.5%) subjects and lower in relatives of unipolar subjects (1.0%). The morbid risks of relatives for bipolar II disorder distinguished bipolar II subjects (6.1%) from bipolar I subjects (1.8%), from unipolar depressives (0.3%) and from controls (0.5%). To promote further evaluation, bipolar II disorder should be included in DSM-IV as a distinct diagnostic category.

journal_name

Acta Psychiatr Scand

authors

Heun R,Maier W

doi

10.1111/j.1600-0447.1993.tb03372.x

subject

Has Abstract

pub_date

1993-04-01 00:00:00

pages

279-84

issue

4

eissn

0001-690X

issn

1600-0447

journal_volume

87

pub_type

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