Abstract：
OBJECTIVE:To determine whether adolescents who self-harm are at increased risk of heavy and dependent substance use in adulthood. METHOD:Fifteen-year prospective cohort study of a random sample of 1943 adolescents recruited from secondary schools across the state of Victoria, Australia. Data pertaining to self-harm and substance use was obtained at seven waves of follow-up, from mean age 15.9 years to mean age 29.1 years. RESULTS:Substance use and self-harm were strongly associated during the adolescent years (odds ratio (OR): 3.3, 95% CI 2.1-5.0). Moreover, adolescent self-harmers were at increased risk of substance use and dependence syndromes in young adulthood. Self-harm predicted a four-fold increase in the odds of multiple dependence syndromes (sex- and wave-adjusted OR: 4.2, 95% CI: 2.7-6.6). Adjustment for adolescent anxiety/depression attenuated but did not eliminate most associations. Adolescent substance use confounded all associations, with the exception of multiple dependence syndromes, which remained robustly associated with adolescent self-harm (fully adjusted odds ratio: 2.0, 95% CI: 1.2-3.2). CONCLUSION:Adolescent self-harm is an independent risk factor for multiple dependence syndromes in adulthood. This level of substance misuse is likely to contribute substantially to the premature mortality and disease burden experienced by individuals who self-harm.
journal_name
Acta Psychiatr Scandjournal_title
Acta psychiatrica Scandinavicaauthors
Moran P,Coffey C,Romaniuk H,Degenhardt L,Borschmann R,Patton GCdoi
10.1111/acps.12306subject
Has Abstractpub_date
2015-01-01 00:00:00pages
61-8issue
1eissn
0001-690Xissn
1600-0447journal_volume
131pub_type
杂志文章abstract：OBJECTIVE:Treatment of schizophrenia is frequently complicated by patients' ambivalence and lack of insight into the disease, occasionally warranting involuntary treatment. This study aims to describe involuntary treatment in Danish schizophrenia patients. METHOD:Patients diagnosed with a lifetime ICD-10 F20 schizophr...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/acps.12144
更新日期：2014-04-01 00:00:00
abstract：:The results of a 5-year follow-up study of 76 patients in a crisis intervention ward who were suffering from an adjustment reaction (brief or prolonged depressive reaction) according to ICD-9 criteria indicate a rather favorable course and outcome using standardized instruments. Only 17% developed a chronic or severe ...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1991.tb01426.x
更新日期：1991-07-01 00:00:00
abstract：:Neuroleptic side-effects adversely affect clinical outcome in schizophrenic patients. Clinicians therefore require an understanding of the impact of such side-effects. This study compared psychiatrists' estimates of the prevalence of neuroleptic side-effects and associated distress with schizophrenic patients' reports...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1998.tb09969.x
更新日期：1998-01-01 00:00:00
abstract：OBJECTIVE:Antidepressant medications are efficacious overall; however, some individuals experience worsening mood symptoms and increased suicidal ideation (SI) during treatment. We examined the quantitative electroencephalographic (QEEG) cordance biomarker of brain function biomarker in relation to treatment-emergent s...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1600-0447.2010.01560.x
更新日期：2010-12-01 00:00:00
abstract：OBJECTIVE:To examine the reliability of a brief instrument to assess coping with symptoms by patients with psychotic illness. METHOD:A semi-structured interview (MACS) was developed to assess the amounts of distress, control and coping in relation to psychotic symptoms. Two raters interviewed 23 symptomatic but stable...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1034/j.1600-0447.2001.00324.x
更新日期：2001-06-01 00:00:00
abstract：OBJECTIVE:To investigate the impact of childhood trauma on the clinical course of panic disorder and possible contributing factors. METHOD:Longitudinal data of 539 participants with a current panic disorder were collected from the Netherlands Study of Depression and Anxiety (NESDA). Childhood trauma was assessed with ...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/acps.12726
更新日期：2017-06-01 00:00:00
abstract：OBJECTIVE:The current study aimed to compare specific cognitive profiles corresponding to auditory verbal hallucinations (AVH) status and elucidate which pattern of cognitive deficits may predict voice-hearing status. METHOD:Clinical participants with schizophrenia spectrum disorders were partitioned into: (i) current...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/acps.13169
更新日期：2020-06-01 00:00:00
abstract：OBJECTIVE:Behaviour therapy with exposure and response prevention (ERP) or cognitive behavioural therapy (CBT) including ERP are considered the psychological treatments of choice for obsessive-compulsive disorder (OCD), but group CBT/ERP has received relatively little research attention in the treatment of OCD. The aim...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章,meta分析,评审
doi：10.1111/j.1600-0447.2008.01270.x
更新日期：2009-02-01 00:00:00
abstract：:During the Second World War 70,000-75,000 Finnish children were sent to Sweden to protect them from the war. This article describes a group of children sent to Sweden from Kuopio County. The management of this group is discussed in light of their health, education and profession in adulthood. The change in culture and...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1989.tb01338.x
更新日期：1989-09-01 00:00:00
abstract：OBJECTIVE:Bipolar disorder in children and adolescents is less well studied than bipolar disorder in adults. This review addresses issues related to its underdiagnosis, precursors of bipolarity, comorbidity, natural course and treatment. METHOD:Literature from Medline and other searches, and earlier relevant articles ...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章,评审
doi：10.1034/j.1600-0447.2000.102003162.x
更新日期：2000-09-01 00:00:00
abstract：:A modified version of the revised Personality Diagnostic Questionnaire (PDQ-R), based on DSM-III-R personality disorders (PD), was completed by 74 psychiatric patients. A factor analysis of the scores for each of the PD (i.e. of the number of positive DSM-III-R criteria for each of the PD) yielded 3 factors that defin...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1991.tb03194.x
更新日期：1991-12-01 00:00:00
abstract：:This article examines admission rates for schizophrenia in terms of degree of urbanization. Patient data was obtained from the Dutch psychiatric register. The scale of urbanization used had five categories and was utilized to establish the degree of urbanization in each municipality (n=647). Admission rates showed a s...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1997.tb10167.x
更新日期：1997-10-01 00:00:00
abstract：OBJECTIVE:Prognostic studies of major depression have mainly focused on episode remission and relapse, and only a limited number of studies have examined long-term course of depressive symptomatology at threshold and subthreshold levels. METHOD:The Group for Longitudinal Affective Disorders Study has conducted prospec...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.2008.01288.x
更新日期：2009-04-01 00:00:00
abstract：OBJECTIVE:To identify psychopathological predictors for suicide in a population of major depressed Diagnostic Statistical Manual-III (DSM-III) in-patients. METHOD:A total of 210 previous participants in multicentre antidepressant drug trials, carried out in a randomized double-blind design, were followed prospectively...
journal_title：Acta psychiatrica Scandinavica
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2003-06-01 00:00:00
abstract：:The present evaluation focused on the inter-rater reliability of single items and subscales of the Positive and Negative Syndrome Scale (PANSS) before and after a standardized rater training. The results of two independent studies comprising n=23 (study I) and n=12 (study II) psychiatrists and videotaped interviews wi...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1998.tb10055.x
更新日期：1998-08-01 00:00:00
abstract：OBJECTIVE:The endocannabinoid (EC) system is widely distributed throughout the brain and modulates many functions. It is involved in mood and related disorders, and its activity may be modified by exogenous cannabinoids. This article examines the therapeutic potential of cannabinoids in psychiatric disorders. METHOD:A...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章,评审
doi：10.1111/j.1600-0447.2011.01687.x
更新日期：2011-10-01 00:00:00
abstract：OBJECTIVES:This study aimed to estimate the commitment to mental health research by the European Union (EU) through the 7th framework (FP7) and the competitiveness and innovation (CIP) programmes during the 2007-2013 period. METHODS:Research projects dedicated or partially related to mental health were identified usin...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/acps.12584
更新日期：2016-08-01 00:00:00
abstract：OBJECTIVE:We examined the prevalence and determinants of the reasons given for non-adherence to psychiatric medication in a representative community survey. METHOD:We used data for all participants taking oral psychotropic medication (n = 634) from the 2000 British Survey of National Psychiatric Morbidity. RESULTS:Of...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.2006.00974.x
更新日期：2007-07-01 00:00:00
abstract：OBJECTIVE:To give an update on epidemiological findings on sex differences in the prevalence of unipolar depression and putative risk factors. MATERIAL AND METHODS:Systematic review of the literature. RESULTS:Recent epidemiological research yields additional evidence for a female preponderance in unipolar depression,...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章,评审
doi：10.1034/j.1600-0447.2003.00204.x
更新日期：2003-09-01 00:00:00
abstract：OBJECTIVE:Relocations after disasters are known to cause added distress in survivors. This study examined the effects of migration and other factors on psychological status of survivors 4 years after the two severe earthquakes in Turkey. METHOD:Five hundred and twenty-six adult survivors of the 1999 earthquakes curren...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.2006.00786.x
更新日期：2006-09-01 00:00:00
abstract：:We investigated past suicidal behaviour and family history of suicide in 713 inpatients with major depressive illness. A familial history of suicide (mainly violent) significantly increased the frequency of violent suicidal behaviour in depressive women; bipolar patients being more affected than unipolars. In depresse...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1985.tb02600.x
更新日期：1985-09-01 00:00:00
abstract：OBJECTIVE:The paper provides the first syllabus on the prevalence of mental disorders in old-age focusing on surveys conducted in the 15 countries, which comprised the 'old' European Union. METHOD:A systematic search of the literature published from 1990 onwards was conducted. RESULTS:Mental disorders in old-age are ...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章,评审
doi：10.1111/j.1600-0447.2005.00632.x
更新日期：2006-05-01 00:00:00
abstract：OBJECTIVE:To determine whether the prescription of aripiprazole, compared with olanzapine and haloperidol, was associated with a lower frequency of metabolic syndrome (MS) and treatment discontinuation at 1 year. METHOD:Patients were randomly assigned to be treated open-label and according to usual clinical practice w...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章,随机对照试验
doi：10.1111/acps.12468
更新日期：2016-01-01 00:00:00
abstract：INTRODUCTION:This paper reviews studies on outcomes of involuntary hospital admissions in general adult psychiatry, and predictors of outcomes. METHOD:Studies assessing observer-rated clinical change and self-rated outcomes were identified. Relevant databases were searched and authors were contacted. Studies were clas...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章,评审
doi：10.1111/j.1600-0447.2006.00823.x
更新日期：2006-10-01 00:00:00
abstract：:The pathophysiology behind the abnormalities of the hypothalamic pituitary adrenal cortex axis found in patients with major depressive disorder was studied by the use of the vasopressin test. The response of plasma adrenocorticotropin (ACTH) and cortisol to the injection of 10 IU lysine-vasopressin (LVP) was investiga...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1988.tb05142.x
更新日期：1988-04-01 00:00:00
abstract：OBJECTIVE:Literature suggests that childhood trauma increases vulnerability for schizophrenia-spectrum disorders, including schizotypal personality disorder (SPD). Yet, it remains unexplored whether childhood trauma predicts symptom load and the level of neurocognitive functioning in SPD. METHOD:We included 225 indivi...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/acps.13032
更新日期：2019-07-01 00:00:00
abstract：OBJECTIVE:Patients who engage in recurrent deliberate self-harm (DSH) behaviours have increased morbidity and mortality and use emergency services more than others. Unrecognized iatrogenic injury may play a role. Specifically, we call attention to the potential danger of cumulative radiation exposure. METHOD:Case pres...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.2010.01538.x
更新日期：2010-11-01 00:00:00
abstract：:Interviews were conducted with 21 patients classified as neurotic or prepsychotic/psychotic, consecutively admitted to an intensive care unit (ICU) owing to suicide attempts by means of drug intoxication, with their 37 significant others and with care personnel concerning the patients' contacts with psychiatric, somat...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1987.tb02803.x
更新日期：1987-04-01 00:00:00
abstract：:An ethological method was employed to validate the DSM-III subtyping of unipolar, nondelusional depression. The nonverbal behavior of 44 depressed outpatients was video-recorded during psychiatric interview. The DSM-III subtyping was not significantly associated with sex or level of education. Patients with major depr...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1990.tb05499.x
更新日期：1990-06-01 00:00:00
abstract：:In a catchment area study of 101 first inceptions of schizophrenia, mania and atypical psychoses, women were significantly more likely to have atypical psychosis and men were more likely to have definite schizophrenia. Negative symptoms such as affective flattening and poverty of speech were already present in many ca...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1991.tb03182.x
更新日期：1991-12-01 00:00:00
