Gender differences in unipolar depression: an update of epidemiological findings and possible explanations.

Abstract:

OBJECTIVE:To give an update on epidemiological findings on sex differences in the prevalence of unipolar depression and putative risk factors. MATERIAL AND METHODS:Systematic review of the literature. RESULTS:Recent epidemiological research yields additional evidence for a female preponderance in unipolar depression, holding true across different cultural settings. Current explanations include artefacts, genetic, hormonal, psychological and psychosocial risk factors. Rather consistently, intrapsychic and psychosocial gender role related risk factors have been identified which may contribute to the higher depression risk in women. Gender role aspects are also reflected in endocrine stress reactions and possibly influence associated neuropsychological processes. CONCLUSION:There is a need for more integrative models taking into account psychological, psychosocial, and macrosocial risk factors as well as their interactions, which also connect these factors with physiological and endocrine responses. Furthermore, it is conceivable that across the life span, as well as across cultural settings, individual risk factors will add with varying emphasis to the higher prevalence of depression in women.

journal_name

Acta Psychiatr Scand

authors

Kuehner C

doi

10.1034/j.1600-0447.2003.00204.x

subject

Has Abstract

pub_date

2003-09-01 00:00:00

pages

163-74

issue

3

eissn

0001-690X

issn

1600-0447

pii

204

journal_volume

108

pub_type

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