Comorbid personality disorder predicts suicide after major depression: a 10-year follow-up.

Abstract:

OBJECTIVE:To identify psychopathological predictors for suicide in a population of major depressed Diagnostic Statistical Manual-III (DSM-III) in-patients. METHOD:A total of 210 previous participants in multicentre antidepressant drug trials, carried out in a randomized double-blind design, were followed prospectively through a maximum of 10 years. Patients with a drug or alcohol abuse were excluded. The association between suicide and the pretreatment psychopathological profile was analysed using survival statistics. RESULTS:The suicide rate for non-melancholic depressed patients was significantly higher than for melancholic depressed patients. Comorbid personality disorder was independently associated with an increased suicide rate [relative hazard 3.41(CI: 1.15-10.10)]. CONCLUSION:The study indicates that the non-melancholic aspect of depression, and especially comorbid personality disorder, is associated with an increased suicidal vulnerability.

journal_name

Acta Psychiatr Scand

authors

Hansen PE,Wang AG,Stage KB,Kragh-Sorensen P,Danish University Antidepressant Group.

subject

Has Abstract

pub_date

2003-06-01 00:00:00

pages

436-40

issue

6

eissn

0001-690X

issn

1600-0447

pii

2o048

journal_volume

107

pub_type

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