Abstract：
:This study evaluates the utilization of clozapine in the treatment of therapy-refractory schizophrenia in terms both of patterns of care and of health care costs in a community psychiatric service in Italy. Data covering the year prior to commencing clozapine and the year following the initiation of the therapy were collected. Clinical outcome was assessed by means of the Clinical Global Impression (CGI) and Global Assessment of Functioning (GAF) scales. Cost analysis followed a two-step procedure: (i) to record all health care services provided to patients and (ii) to assign a monetary value to each service. Three of the 15 patients enrolled in the study dropped out before the end of the 12-month period of therapy. Considering the 12 patients on clozapine treatment for at least 1 year, clinical improvements are associated with a substantial modification of the pattern of care. While patients in the pre-clozapine period were mainly managed in hospital settings, patients on clozapine were prevalently placed in the community and participated in intensive rehabilitative programmes. The higher costs of drug therapy and community services in the post-clozapine period were more than offset by the lower costs of acute hospital care.
journal_name
Acta Psychiatr Scandjournal_title
Acta psychiatrica Scandinavicaauthors
Percudani M,Fattore G,Galletta J,Mita PL,Contini A,Altamura ACdoi
10.1111/j.1600-0447.1999.tb07225.xsubject
Has Abstractpub_date
1999-04-01 00:00:00pages
274-80issue
4eissn
0001-690Xissn
1600-0447journal_volume
99pub_type
杂志文章abstract：:Ninety men between the ages of 20 to 65 were studied to investigate the relationships between stress, depression and psychogenic pain. Three groups (the coronary heart disease (CHD) group; the left-sided psychogenic chest pain (LPCP) group; and the control group) comprising 30 patients per group, each completed the So...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1993.tb03406.x
更新日期：1993-07-01 00:00:00
abstract：OBJECTIVE:Employment outcome in bipolar disorder is an under investigated, but important area. The aim of this study was to identify the long-term employment outcomes of people with bipolar disorder. METHOD:A systematic review using the Medline, PsychInfo and Web of Science databases. RESULTS:Of 1962 abstracts retrie...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章,评审
doi：10.1111/acps.12087
更新日期：2013-09-01 00:00:00
abstract：:A prospective study of 167 consecutive patients admitted to a general hospital following an episode of deliberate self-harm was carried out; 102 patients were interviewed by computer and then by a psychiatrist who was blind to the results of the computer interview. The computer interview consisted of a self-rating mod...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1989.tb01330.x
更新日期：1989-09-01 00:00:00
abstract：:A total of 1600 adolescents between the ages of 13 and 16 living in a county bordering on Paris were interviewed concerning their health, their use of drugs, both legal and illegal, their behavior, and their seeking of health care. Fourteen percent of the boys and 23% of the girls had already thought about suicide and...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1990.tb06474.x
更新日期：1990-02-01 00:00:00
abstract：:The purpose of this study is to reveal the relationship between family expressed emotion (EE) and family evaluation for symptoms and social adjustment of schizophrenic patients. Chronic schizophrenic outpatients in offshore islands under stationary therapeutic conditions were studied. For evaluation, the Five Minute S...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1994.tb01496.x
更新日期：1994-02-01 00:00:00
abstract：:In recent discussions on euthanasia the question about mercy killing without consent of mentally ill persons has turned up, particularly in cases of hopeless suffering among senile or chronically insane patients. Possible analogies to the actions under the German Nazi-regimen and relations to the concept of Social Dar...
journal_title：Acta psychiatrica Scandinavica
pub_type： 历史文章,杂志文章
doi：10.1111/j.1600-0447.1982.tb00832.x
更新日期：1982-02-01 00:00:00
abstract：OBJECTIVE:This study was designed to investigate the association between major mental disorders (MMDs) and homicide. METHOD:The rates of exculpations because of MMDs among 1087 Austrian homicide offenders during 1975 and 1999 were compared with the rates of the respective disorders in the general population. RESULTS:...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0047.2004.00305.x
更新日期：2004-08-01 00:00:00
abstract：:Can it be said that history's most outstanding psychiatrists and the various interrelated fields of mental health are to any extent realistically represented within the framework of thematic philately? With regard to the latter theme, five main categories can be distinguished: the mentally handicapped; psychiatric ins...
journal_title：Acta psychiatrica Scandinavica
pub_type：
doi：10.1111/j.1600-0447.1988.tb05105.x
更新日期：1988-02-01 00:00:00
abstract：:Eighty Kenyan 'psychotic' patients were screened using the New Haven Schizophrenic Index (NHSI) and were all studied for hallucinations using standardised definitions. Fifty-one of the patients were NHSI positive and the rest NHSI negative. Sixty-one percent of the NHSI positive had hallucinations in one or more modal...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1983.tb00334.x
更新日期：1983-03-01 00:00:00
abstract：OBJECTIVE:Non-suicidal self-injury (NSSI) comprising thoughts and behaviors is common and often co-occurring with suicidal behavior like ideation, plan, and attempt. As limited data are available for adolescents and young adults, this study aims to present prevalence estimates for lifetime NSSI, its co-occurrence with ...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/acps.13237
更新日期：2020-12-01 00:00:00
abstract：:The relationship between brain density, measured by computerized tomography (CT), and severity of depression was investigated in 44 patients with a major depressive episode according to DSM-III. In order to limit methodological problems, correlations between both the Brief Psychiatric Rating Scale (BPRS) and the Bech-...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1988.tb06392.x
更新日期：1988-11-01 00:00:00
abstract：:Vitamin B12 levels in the serum and the cerebrospinal fluid (CSF) were compared between patients with Alzheimer's disease (AD) and senile dementia of Alzheimer's type (SDAT) (AD group) and patients with multi-infarct dementia (MID group). The B12 levels in the serum and the CSF were 742 +/- 359 pg/ml and 28 +/- 7 pg/m...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1990.tb01395.x
更新日期：1990-10-01 00:00:00
abstract：:In a study of psychotherapy in schizophrenic patients, the existence of certain clinical and anamnestic variables, such as persistent auditory hallucinations, was found to correlate with a negative outcome. To test whether these clinical variables could be a sign of organic brain abnormality, the records of 33 schizop...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1992.tb03299.x
更新日期：1992-12-01 00:00:00
abstract：:Neuroleptic side-effects adversely affect clinical outcome in schizophrenic patients. Clinicians therefore require an understanding of the impact of such side-effects. This study compared psychiatrists' estimates of the prevalence of neuroleptic side-effects and associated distress with schizophrenic patients' reports...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1998.tb09969.x
更新日期：1998-01-01 00:00:00
abstract：OBJECTIVE:Major Depressive Disorder (MDD) is a major cause of long-term work disability. However, factors predicting this are not well known. METHOD:In the Vantaa Depression Study, predictors for being granted a disability pension during an 18-month follow-up were examined among the 186 psychiatric MDD in- and out-pat...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.2006.00878.x
更新日期：2007-03-01 00:00:00
abstract：OBJECTIVE:We examined the relationship between biological rhythms and severity of depressive symptoms in subjects with bipolar disorder and the effects of biological rhythms alterations on functional impairment. METHOD:Bipolar patients (n = 260) and healthy controls (n = 191) were recruited from mood disorders program...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/acps.12442
更新日期：2016-02-01 00:00:00
abstract：OBJECTIVE:To determine the prevalence, psychiatric comorbidity and suicidal ideation associated with co-occurring non-affective psychosis and panic attacks, compared with non-affective psychosis without panic attacks, in the general population. METHOD:Data were drawn from the National Comorbidity Survey (n = 8098). St...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1034/j.1600-0447.2002._10424.x
更新日期：2002-01-01 00:00:00
abstract：OBJECTIVE:To compare the rates of suicidal behaviour during vs. after discontinuation of treatment with antidepressants, and to determine the comparative rates of suicidal behaviour for patients maintained on tricyclic (TCA) vs. selective serotonin reuptake inhibitor (SSRI) antidepressants. METHOD:Charts were reviewed...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.2004.00437.x
更新日期：2004-12-01 00:00:00
abstract：:The aim of the study was to examine the social and economic variables associated with mental health by means of telephone interviews of a randomly chosen population sample (n = 1557) in Finland in 1993. Mental health was evaluated by means of a 12-item General Health Questionnaire. A mental disorder, indicated by the ...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1995.tb09570.x
更新日期：1995-09-01 00:00:00
abstract：OBJECTIVE:Lycanthropy is an unusual psychiatric syndrome involving the delusion of being an animal. Cotard's syndrome is another rare condition in which the patient has nihilistic delusions and ideation of immortality. We report a psychiatric patient who had both syndromes simultaneously. METHOD:A single case was repo...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.2004.00438.x
更新日期：2005-03-01 00:00:00
abstract：OBJECTIVE:There is a high prevalence of depression in south Asian women. We aimed to examine the association between antenatal depression and low birthweight (LBW) in infants in a rural community in Rawalpindi, Pakistan. METHOD:A total of 143 physically healthy mothers with ICD-10 depression in the third trimester of ...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.2006.00950.x
更新日期：2007-06-01 00:00:00
abstract：:In a prospective study a number of women and their husbands were interviewed early on in the pregnancy, in the week after delivery and again 4 months later. The couvade syndrome, in which the father-to-be suffers from somatic symptoms of psychogenic origin connected in some way with his wife's pregnancy, was investiga...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1983.tb06981.x
更新日期：1983-07-01 00:00:00
abstract：:The platelet levels of serotonin and the amino acids aspartic acid, glutamine, glutamic acid and gamma-aminobutyric acid were measured in 18 drug-free autistic (DSM-III criteria) and 14 age-matched healthy children. Serotonin was significantly increased while the amino acids aspartic acid, glutamine, glutamic acid and...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1993.tb03378.x
更新日期：1993-05-01 00:00:00
abstract：OBJECTIVE:To examine age, period and cohort effects on Australian suicide rates. METHOD:Male suicide rates for successive 5-year periods between 1919 and 1998, and for 1999 were displayed graphically to examine interactions between age, period and cohort effects. RESULTS:There has been a pronounced period effect on m...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1034/j.1600-0447.2002.1193.x
更新日期：2002-04-01 00:00:00
abstract：:A multi-variate multiple regression analysis was carried out to screen the crucial characteristics of alcohol abusers immediately prior to pension in order to indicate their subsequent trends. Stepwise multiple regression analyses were performed in the younger and older subgroups, as well as in 56 first-time pension a...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1983.tb00951.x
更新日期：1983-12-01 00:00:00
abstract：OBJECTIVE:To investigate whether large social networks are associated with better functional outcome in psychotic disorders. METHOD:A prospective cohort study of epidemiologically representative patients with psychosis was analysed to examine the relationship between social networks and functional outcome. Standardize...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1034/j.1600-0447.2000.102005376.x
更新日期：2000-11-01 00:00:00
abstract：OBJECTIVE:The study aimed to characterize neuropsychiatric symptomatology and its evolution in a large group of poststroke patients during their first year. METHOD:The Neuropsychiatric Inventory (NPI) was administered to a sample of 124 poststroke patients, divided into three independent groups on the basis of time fr...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章,多中心研究
doi：10.1111/j.1600-0447.2004.00297.x
更新日期：2004-07-01 00:00:00
abstract：:The construction of the clinical category dysmorphophobia (now known as body dysmorphic disorder) resulted from the historical convergence of a neologism (coined by Enrico Morselli), a family of clinical concepts (already available during the late 19th century), and a specifiable behaviour (an 'attitude' towards part ...
journal_title：Acta psychiatrica Scandinavica
pub_type： 传,历史文章,杂志文章
doi：10.1111/j.1600-0447.1996.tb09817.x
更新日期：1996-07-01 00:00:00
abstract：:In 103 schizophrenic patients we investigated the extent of practice needed in the use of the Brief Psychiatric Rating Scale (BPRS) to enable its reliability to be assessed. The agreement level of the 7 raters was analysed. Generally, the lowest mean agreement found was for the negative symptoms of the BPRS schizophre...
journal_title：Acta psychiatrica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0447.1993.tb03343.x
更新日期：1993-02-01 00:00:00
abstract：:This article considers the nosology and taxonomy of psychiatric disorders in Sushruta Samhita, an ancient Indian treatise on medicine. Some implications of this treatise for modern psychiatry are discussed. ...
journal_title：Acta psychiatrica Scandinavica
pub_type： 历史文章,杂志文章
doi：10.1111/j.1600-0447.1989.tb01317.x
更新日期：1989-08-01 00:00:00
