Antidepressants and suicidal behaviour in unipolar depression.

Abstract:

OBJECTIVE:To compare the rates of suicidal behaviour during vs. after discontinuation of treatment with antidepressants, and to determine the comparative rates of suicidal behaviour for patients maintained on tricyclic (TCA) vs. selective serotonin reuptake inhibitor (SSRI) antidepressants. METHOD:Charts were reviewed for 521 patients with major depressive disorder and/or dysthymic disorder. Periods of active treatment or discontinuation with SSRIs or TCAs were determined. Rates of completed suicide, suicide attempts, and hospitalization for suicidality were analyzed. RESULTS:There was greater than a five-fold increase in risk for suicidal behaviour after discontinuation of antidepressant treatment (P < 0.0001). The rates of suicidal behavior during treatment with SSRIs or TCAs were similar. CONCLUSION:Suicidal behaviour in unipolar depressed patients treated with antidepressants increases substantially after medication discontinuation. This effect occurred in both patients who were maintained on SSRIs and TCAs. The findings support a possible protective effect on suicidal behaviour for both SSRIs and TCAs.

journal_name

Acta Psychiatr Scand

authors

Yerevanian BI,Koek RJ,Feusner JD,Hwang S,Mintz J

doi

10.1111/j.1600-0447.2004.00437.x

subject

Has Abstract

pub_date

2004-12-01 00:00:00

pages

452-8

issue

6

eissn

0001-690X

issn

1600-0447

pii

ACP437

journal_volume

110

pub_type

杂志文章
  • The effect of sleep deprivation on depressed patients.

    abstract::In this paper an account is given of the effect of single-night sleep deprivation (SD) therapy in 124 depressive patients of different diagnostic groups. Phasic depressives showed a marked improvement after treatment by sleep deprivation. Because these improvements were often of short duration, we repeated the treatme...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1976.tb00068.x

    authors: Pflug B

    更新日期:1976-02-01 00:00:00

  • The 10-year course of PTSD in borderline patients and axis II comparison subjects.

    abstract:OBJECTIVE:The first objective is to detail the prevalence of post-traumatic stress disorder (PTSD) over a decade of follow-up for those in both study groups. The second is to determine time-to-remission, recurrence, and new onset of PTSD, and the third is to assess the relationship between sexual adversity and the like...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.2011.01717.x

    authors: Zanarini MC,Hörz S,Frankenburg FR,Weingeroff J,Reich DB,Fitzmaurice G

    更新日期:2011-11-01 00:00:00

  • Neuroleptic malignant syndrome during olanzapine and levomepromazine treatment.

    abstract:OBJECTIVE:To date only five reports of neuroleptic malignant syndrome (NMS) related to olanzapine exist. The first case report was published in November 1998. METHOD:We report the case of a 78-year-old woman suffering from chronic schizophrenia who developed a NMS while being treated with olanzapine and levomepromazin...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0447.2000.102003231.x

    authors: Järventausta K,Leinonen E

    更新日期:2000-09-01 00:00:00

  • The cultural perspective of therapeutic relationship--a viewpoint from Africa.

    abstract::Therapeutic relationship has been considered an important ingredient of all psychotherapies. In communities in which no familiar conventions of such a relationship are available, the therapeutic encounter poses very different problems from those in the West, where such conventions freely prevail. This study has been c...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1985.tb02547.x

    authors: Neki JS,Joinet B,Hogan M,Hauli JG,Kilonzo G

    更新日期:1985-06-01 00:00:00

  • Maastricht Assessment of Coping Strategies (MACS-I): a brief instrument to assess coping with psychotic symptoms.

    abstract:OBJECTIVE:To examine the reliability of a brief instrument to assess coping with symptoms by patients with psychotic illness. METHOD:A semi-structured interview (MACS) was developed to assess the amounts of distress, control and coping in relation to psychotic symptoms. Two raters interviewed 23 symptomatic but stable...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0447.2001.00324.x

    authors: Bak M,van der Spil F,Gunther N,Radstake S,Delespaul P,van Os J

    更新日期:2001-06-01 00:00:00

  • Nature of the genetic contribution to psychotic illness--a continuum viewpoint.

    abstract::The recurrent psychoses, rather than, as Kraepelin supposed, constituting 2 major entities, manic depressive illness and schizophrenia, as separate diseases, may be distributed along a continuum that extends from unipolar depressive illness through bipolar and schizoaffective psychosis to schizophrenia with increasing...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.1111/j.1600-0447.1990.tb05471.x

    authors: Crow TJ

    更新日期:1990-05-01 00:00:00

  • Housing conditions and residential needs of psychiatric patients in Copenhagen.

    abstract::A study of the extent of homelessness among 1581 psychiatric patients in Copenhagen found that 342 patients (22%) in contact with the psychiatric services had serious housing problems. A total of 112 (7%) were long-stay patients without a home address, 134 (8%) were in an unstable housing situation and 96 (6%) were ac...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1992.tb10324.x

    authors: Nordentoft M,Knudsen HC,Schulsinger F

    更新日期:1992-05-01 00:00:00

  • Selection of patients who attempted suicide for psychiatric consultation.

    abstract::A total of 1018 self-poisoned patients were treated during one year (1983) at the emergency room of Helsinki University Central Hospital for 1207 suicide attempts; 46% were left without psychiatric consultation. Women were consulted more frequently than men. Patients with previous psychiatric treatment were referred m...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1991.tb05520.x

    authors: Suokas J,Lönnqvist J

    更新日期:1991-03-01 00:00:00

  • Offspring of women with nonorganic psychosis: fear of strangers during the first year of life.

    abstract::Fear of strangers ( FOS ) during the infant's first year was studied in 46 "high-risk" offspring of index mothers with a history of nonorganic psychosis and in 80 demographically similar control offspring. FOS was measured in the home by a standardized test at 1 year of age and by repeated interviews with the mother d...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1984.tb02516.x

    authors: Näslund B,Persson-Blennow I,McNeil T,Kaij L,Malmquist-Larsson A

    更新日期:1984-05-01 00:00:00

  • Female alcoholics. V: The relationship between family history of alcoholism and outcome 3-10 years after treatment.

    abstract::In a long-term follow-up study of 44 female alcoholics, a family history of alcoholism was related to younger age of onset of problem drinking, but did not necessarily imply a poorer outcome within this highly selected group of individuals. Alcoholism in father and his family was not related to either antisocial or bo...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1987.tb02857.x

    authors: Haver B

    更新日期:1987-07-01 00:00:00

  • Trends in prevalence of Alzheimer's disease and vascular dementia in a Japanese community: the Hisayama Study.

    abstract:OBJECTIVE:To examine secular trends in the prevalence of Alzheimer's disease (AD) and vascular dementia (VD) in a general Japanese population. METHOD:Four cross-sectional examinations were conducted among residents of a Japanese community aged >or=65 in 1985, 1992, 1998 and 2005. RESULTS:The age- and sex-adjusted pre...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.2010.01587.x

    authors: Sekita A,Ninomiya T,Tanizaki Y,Doi Y,Hata J,Yonemoto K,Arima H,Sasaki K,Iida M,Iwaki T,Kanba S,Kiyohara Y

    更新日期:2010-10-01 00:00:00

  • Self-rated schizotypal cognitions, psychotic symptoms and the onset of schizophrenia in young people at high risk of schizophrenia.

    abstract:OBJECTIVE:To examine the associations between the Rust Inventory of Schizotypal Cognitions (RISC) and psychotic symptoms measured by the Present State Examination (PSE) and to assess the predictive validity of the RISC for later onset of schizophrenia. METHOD:A total of 154 subjects at high risk for schizophrenia but ...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0447.2002.1o175.x

    authors: Miller PM,Lawrie SM,Byrne M,Cosway R,Johnstone EC

    更新日期:2002-05-01 00:00:00

  • Sleep in the premenstrual phase: a self-report study of PMS patients and normal controls.

    abstract::Sleep disturbances commonly occur in the premenstruum in both Premenstrual Syndrome (PMS) patients and in women from the general population. Reports on the Post-Sleep Inventory were obtained from a clinic sample of PMS patients and samples from the general population dichotomized into a non-clinic group with and witho...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1988.tb06304.x

    authors: Mauri M,Reid RL,MacLean AW

    更新日期:1988-07-01 00:00:00

  • Fatal antidepressant overdose among drug abusers and non-drug abusers.

    abstract:OBJECTIVE:This study examined the predictors, extent and pattern of fatal antidepressant overdose (FAO) in all psychoactive drug-related deaths and compared these in drug abusers and non-drug abusers. METHOD:Inquest data on 491 psychoactive drug-related cases in England and Wales were analysed. We examined predictors ...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0447.2000.102004295.x

    authors: Oyefeso A,Valmana A,Clancy C,Ghodse H,Williams H

    更新日期:2000-10-01 00:00:00

  • Psychopathology and treatment of 30,344 twins in Sweden. I. The appropriateness of psychoactive drug treatment.

    abstract::We studied whether regular treatment with tranquilizing and hypnotic drugs among 30,344 twins in Sweden 15-47 years old was associated with robust indicators of poor health. Longitudinal psychiatric diagnoses and subsequent suicides were analyzed with data from cross-sectional health questionnaires. Women were almost ...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1990.tb03072.x

    authors: Allgulander C,Nowak J,Rice JP

    更新日期:1990-12-01 00:00:00

  • Age and other factors relevant to the rehospitalization of schizophrenic outpatients.

    abstract::In this study 50 of 51 schizophrenic long-term patients treated by a community-based outpatient service were followed-up for 2 years. Factors known to be relevant for rehospitalization were correlated with the rate of hospitalizations 1) in the past, 2) during the last year and 3) during the follow-up period. We were ...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1994.tb08093.x

    authors: Hoffmann H

    更新日期:1994-03-01 00:00:00

  • Lithium and hair texture.

    abstract::Patients receiving lithium who had noticed changes in hair texture since starting that drug, described variously as hair losing its curl or wave, have a greater lithium concentration in hair than patients on lithium with no such complaints. ...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1985.tb02626.x

    authors: McCreadie RG,Farmer JG

    更新日期:1985-10-01 00:00:00

  • The truth about suicide in Portugal.

    abstract::It seems odd that male suicide rates have decreased in Portugal over the last few years, whereas the opposite has happened in most other countries. In order to investigate the reasons for such a decrease, suicide rates were compared with controversial cases (ICD-9 category E 980-989) and with homicide rates. The resul...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1989.tb02989.x

    authors: de Castro EF,Pimenta F,Martins I

    更新日期:1989-10-01 00:00:00

  • An association between YKL-40 and type 2 diabetes in psychotic disorders.

    abstract:OBJECTIVE:This study examines if YKL-40 is increased in individuals with psychotic disorders and if elevated YKL-40 levels at baseline is associated with subsequent development of type 2 diabetes. METHOD:A total of 1383 patients with a diagnosis of schizophrenia or affective psychosis and 799 healthy controls were rec...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/acps.12971

    authors: Dieset I,Mørch RH,Hope S,Hoseth EZ,Reponen EJ,Gran JM,Aas M,Michelsen AE,Reichborn-Kjennerud T,Nesvåg R,Agartz I,Melle I,Aukrust P,Djurovic S,Ueland T,Andreassen OA

    更新日期:2019-01-01 00:00:00

  • Prognosis of treated hypochondriasis. A clinical study.

    abstract::Thirty-six patients who had hypochondriacal neurosis for 6 months or longer were treated with individual psychotherapy which focused predominantly on presenting complaints, fears and beliefs. Antianxiety drugs were used at times of anxiety. Sixty-four percent either recovered or improved to the extent that they no lon...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1983.tb06725.x

    authors: Kellner R

    更新日期:1983-02-01 00:00:00

  • A case of organic brain syndrome following head injury successfully treated with carbamazepine.

    abstract::A case of organic brain syndrome occurring in relation to psychological stress 2 years after a severe head injury is described. Treatment with haloperidol resulted only in slight improvement. A dramatic improvement was achieved with carbamazepine. ...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1988.tb05136.x

    authors: Bouvy PF,van de Wetering BJ,Meerwaldt JD,Bruijn JB

    更新日期:1988-03-01 00:00:00

  • Reliability of an Italian standardized and expanded Brief Psychiatric Rating Scale (BPRS 4.0) in raters with high vs. low clinical experience.

    abstract:OBJECTIVE:The aims of this study were (i) to assess the inter-rater reliability of the latest Italian expanded 24-item version of the Brief Psychiatric Rating Scale, BPRS version 4.0 and (ii) to assess the feasibility of obtaining reliable BPRS 4.0 ratings by reliability training of clinically less experienced trainees...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1999.tb10850.x

    authors: Roncone R,Ventura J,Impallomeni M,Falloon IR,Morosini PL,Chiaravalle E,Casacchia M

    更新日期:1999-09-01 00:00:00

  • Cognitive behaviour therapy with coping training for persistent auditory hallucinations in schizophrenia: a naturalistic follow-up study of the durability of effects.

    abstract:OBJECTIVE:To investigate the durability of positive effects of cognitive behaviour therapy (CBT) with coping training on psychotic symptoms and social functioning. METHOD:Forty patients with schizophrenia or related psychotic disorders and refractory auditory hallucinations were given CBT and coping training in an int...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0447.2001.00213.x

    authors: Wiersma D,Jenner JA,van de Willige G,Spakman M,Nienhuis FJ

    更新日期:2001-05-01 00:00:00

  • Increased use of primary care during 6 years of prodromal schizophrenia.

    abstract:BACKGROUND:Early diagnosis is important for the course of schizophrenia. AIM:To investigate whether prodromal symptoms of schizophrenia lead to increased use of primary care. METHOD:A register-based cohort study of 21 894 cases with incident schizophrenia and 437 880 matched controls. RESULTS:Cases used daytime prim...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/acps.12600

    authors: Nørgaard H,Søndergaard Pedersen H,Fenger-Grøn M,Mors O,Nordentoft M,Vestergaard M,Munk Laursen T

    更新日期:2016-09-01 00:00:00

  • Interviews with psychiatric inpatients about professional intervention with regard to their children.

    abstract::A description of mentally ill parents' experience and points of view concerning professional intervention in relation to their young children is presented in this paper. The results are from an interview survey designed with the purpose of improving the basis for cooperation between mentally ill patients and professio...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1996.tb10619.x

    authors: Wang AR,Goldschmidt VV

    更新日期:1996-01-01 00:00:00

  • Beck's Depression Inventory as a screening instrument for adolescent depression in Sweden: gender differences.

    abstract::Beck's Depression Inventory was administered in a study of all students aged 16-17 years in the first year of high school in a Swedish town, and was completed by 93% of them (n = 2270). Cronbach's reliability coefficient alpha was 0.89, and there were strong correlations between item scores and total scores. A diagnos...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1997.tb09632.x

    authors: Olsson G,von Knorring AL

    更新日期:1997-04-01 00:00:00

  • Preventing breast cancer in women with schizophrenia.

    abstract:OBJECTIVE:To record risk factors for breast cancer in women with schizophrenia and recommend preventive actions. METHOD:A PubMed literature search (from 2005 to 2010) was conducted, using the search terms 'schizophrenia', 'antipsychotics', 'breast cancer' and 'risk factors'. RESULTS:Several risk factors of relevance ...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.2010.01626.x

    authors: Seeman MV

    更新日期:2011-02-01 00:00:00

  • Childhood experiences and personality traits in patients with motor conversion symptoms.

    abstract::A total of 30 patients with newly diagnosed motor conversion disorder were consecutively investigated by means of a Swedish self-rating inventory designed to assess perceived parental rearing practices (EMBU), and the Karolinska Scale of Personality (KSP). DSM Axis I and II psychopathology was assessed using a Structu...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1998.tb10086.x

    authors: Binzer M,Eisemann M

    更新日期:1998-10-01 00:00:00

  • A placebo-controlled comparison of zotepine versus chlorpromazine in patients with acute exacerbation of schizophrenia.

    abstract:OBJECTIVE:The aim of this study was to evaluate the efficacy of zotepine in the treatment of acute episodes of schizophrenia. METHOD:Patients with acute exacerbation of schizophrenia (DSM-III-R criteria; n = 158) were allocated on a random, double-blind basis to receive zotepine (150 or 300 mg/day), chlorpromazine (30...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:

    authors: Cooper SJ,Tweed J,Raniwalla J,Butler A,Welch C

    更新日期:2000-03-01 00:00:00

  • Immune system-associated antigens on the surface of peripheral blood lymphocytes in patients with Alzheimer's disease.

    abstract::We investigated the immune-associated antigens of peripheral lymphocytes from 13 patients with Alzheimer's disease (AD) and 13 age-matched healthy control subjects using two-color analysis with flow cytometry. Four ratios of immune-related antigens, T/B lymphocytes, CD4/CD8, CD4/CD45R and CD4/HLA-DR, were compared for...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1991.tb05573.x

    authors: Ikeda T,Yamamoto K,Takahashi K,Yamada M

    更新日期:1991-06-01 00:00:00