Abstract:
:We investigated the immune-associated antigens of peripheral lymphocytes from 13 patients with Alzheimer's disease (AD) and 13 age-matched healthy control subjects using two-color analysis with flow cytometry. Four ratios of immune-related antigens, T/B lymphocytes, CD4/CD8, CD4/CD45R and CD4/HLA-DR, were compared for the AD and control groups. The T/B and CD4/CD8 ratios did not differ between the groups, the ratio of CD4+CD45R+ subset in the AD group was lower than the ratio in the control group, and the ratios of CD4+ CD45R- and CD4+HLA-DR+ subsets in the AD group were significantly higher. Further, in the AD group, the CD4+ CD45R+/CD4+ ratio was lower and the CD4+ CD45R- CD4+ ratio was higher than in the control group.
journal_name
Acta Psychiatr Scandjournal_title
Acta psychiatrica Scandinavicaauthors
Ikeda T,Yamamoto K,Takahashi K,Yamada Mdoi
10.1111/j.1600-0447.1991.tb05573.xsubject
Has Abstractpub_date
1991-06-01 00:00:00pages
444-8issue
6eissn
0001-690Xissn
1600-0447journal_volume
83pub_type
杂志文章abstract::The subjective quality of life (QOL) (i.e. individual evaluation of one's life experiences) has been studied according to a series of different parameters such as resource availability, and sociodemographic and clinical variables, at times yielding contradictory results. Subjective quality of life and standard of life...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1997.tb10157.x
更新日期:1997-10-01 00:00:00
abstract::The care of mentally ill people at home is being encouraged nowadays. As a result, the family members feel an increased burden of care and find it difficult to cope with the care of a schizophrenic patient at home. We interviewed the relatives of 62 schizophrenics systematically regarding the behaviour of the patients...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1992.tb03249.x
更新日期:1992-09-01 00:00:00
abstract:OBJECTIVE:Depression in bipolar disorder (BipD) requires a therapeutic approach that is from treating unipolar major depressive disorder (UniD), but to date, no reliable methods could separate these two disorders. The aim of this study was to establish the clinical validity and utility of a non-invasive functional MRI-...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/acps.12752
更新日期:2017-09-01 00:00:00
abstract::The relationship between patients with acute major depression and chronic affective disorders was investigated in 298 nonpsychotic outpatients. The patients were categorized into 4 groups: major depression only, major depression with dysthymic or cyclothymic disorders, dysthymic or cyclothymic disorder without major d...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1989.tb09228.x
更新日期:1989-01-01 00:00:00
abstract:OBJECTIVE:To investigate for subtypes of bipolar depression using latent class analysis (LCA). METHOD:Participants were recruited through a bipolar disorder (BD) clinic. LCA was undertaken using: (i) symptoms reported on the SCID-IV for the most severe lifetime depressive episode; (ii) lifetime illness features such a...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/acps.12615
更新日期:2016-09-01 00:00:00
abstract:OBJECTIVE:In patients with borderline personality disorder (BPD), data are lacking on characteristics and severity of hallucinations in modalities other than the auditory (verbal) type. The same applies to relationships between hallucinations and the severity of depression, anxiety, schizotypy, and loneliness. METHODS...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/acps.13012
更新日期:2019-05-01 00:00:00
abstract::This article is based on intensive interviews made with 75 Turkish migrant women living in Denmark. The interviews were conducted in the women's own homes, in their own language, and special care was taken to establish an atmosphere of confidence. The methodological problems involved in this kind of research are discu...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1985.tb01286.x
更新日期:1985-03-01 00:00:00
abstract:OBJECTIVE:The amygdala plays a major role in processing emotional stimuli. Fourteen studies using structural magnetic resonance imaging (MRI) have examined the amygdala volume in paediatric and adult patients with bipolar disorder (BD) compared with healthy controls (HC) and reported inconsistent findings. Lithium has ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.2009.01428.x
更新日期:2010-02-01 00:00:00
abstract::A prospective study of 167 consecutive patients admitted to a general hospital following an episode of deliberate self-harm was carried out; 102 patients were interviewed by computer and then by a psychiatrist who was blind to the results of the computer interview. The computer interview consisted of a self-rating mod...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1989.tb01330.x
更新日期:1989-09-01 00:00:00
abstract::The aim of this 12-week, double-blind, parallel group, placebo-controlled study was to compare paroxetine with clomipramine in 367 patients with DSM-III-R defined panic disorder. Efficacy assessments included the daily panic attack diary, the Clinical Global Impression Scale, the Hamilton Anxiety Rating Scale, the Mar...
journal_title:Acta psychiatrica Scandinavica
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1111/j.1600-0447.1997.tb00388.x
更新日期:1997-02-01 00:00:00
abstract:OBJECTIVE:Prefrontal cortical dysfunction has been implicated in the pathophysiology of schizophrenia but it is unclear to what extent these are related to changes in symptomatology as well as task demand. METHOD:We examined the neural correlates of symptom change and task demand during a longitudinal functional magne...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.2010.01632.x
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVE:This study examined the predictors, extent and pattern of fatal antidepressant overdose (FAO) in all psychoactive drug-related deaths and compared these in drug abusers and non-drug abusers. METHOD:Inquest data on 491 psychoactive drug-related cases in England and Wales were analysed. We examined predictors ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1034/j.1600-0447.2000.102004295.x
更新日期:2000-10-01 00:00:00
abstract::Seven chronic psychiatric patients developed signs of polyneuropathy mainly in the lower limbs after receiving chlorprothixene (500-1800 mg/d) from 3 to more than 24 months. The most prominent electroneuromyographic findings were decreased or not measurable motor conduction velocities of the peroneal nerves. Electromy...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1992.tb08604.x
更新日期:1992-03-01 00:00:00
abstract::An indepth study was carried out over 1 year on all instances of overt heterosexual interactions among acute psychiatric patients on mixed-sex intensive treatment units. Sixteen of the 1060 patients treated on the units were involved in nine instances of overt heterosexual interactions. Analysis of the interactions sh...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1981.tb00804.x
更新日期:1981-11-01 00:00:00
abstract::A total of 1070 men and women aged 65 years and over living in the community in Liverpool were interviewed using the Geriatric Mental State. Diagnoses of depression at case and subcase level were made using the GMS-AGECAT package from an initial interview and at follow-up three years later. Data relating to blood pres...
journal_title:Acta psychiatrica Scandinavica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1600-0447.1995.tb09752.x
更新日期:1995-02-01 00:00:00
abstract:OBJECTIVE:To test the hypothesis that not only intrafamiliar childhood abuses inflicted to the patient, but also major losses or other severe life events suffered by the mother within 2 years of patient's birth, are risk factors for the development of dissociative disorders (DDs). METHOD:A multicentric case-control st...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,多中心研究
doi:10.1034/j.1600-0447.2002.01062.x
更新日期:2002-02-01 00:00:00
abstract:INTRODUCTION:This paper reviews studies on outcomes of involuntary hospital admissions in general adult psychiatry, and predictors of outcomes. METHOD:Studies assessing observer-rated clinical change and self-rated outcomes were identified. Relevant databases were searched and authors were contacted. Studies were clas...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0447.2006.00823.x
更新日期:2006-10-01 00:00:00
abstract::Isocarboxazide has been used as long-term treatment for a selected group of 20 depressive patients, of whom some 90% (17/19) were non-responders to treatment with tricyclic antidepressants. At the follow-up the median duration of illness was 162 months, and the median duration of treatment was 42 months. Side-effects ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1980.tb00634.x
更新日期:1980-11-01 00:00:00
abstract::In a long-term follow-up study of 44 female alcoholics, a family history of alcoholism was related to younger age of onset of problem drinking, but did not necessarily imply a poorer outcome within this highly selected group of individuals. Alcoholism in father and his family was not related to either antisocial or bo...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1987.tb02857.x
更新日期:1987-07-01 00:00:00
abstract::To investigate the relationships between pre- and postdexamethasone hypothalamic-pituitary-adrenal (HPA) axis functioning in depression, we measured the levels of baseline and postdexamethasone urinary free cortisol (UFC), plasma cortisol, adrenocorticotropic hormone (ACTH) and beta-endorphin. We found that dexamethas...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1991.tb05580.x
更新日期:1991-06-01 00:00:00
abstract:OBJECTIVE:To investigate whether trauma exposure moderates the genetic correlation between substance use disorders and psychiatric disorders, we tested whether trauma exposure modifies the association of genetic risks for mental disorders with alcohol misuse and nicotine dependence (ND) symptoms. METHODS:High-resoluti...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/acps.12843
更新日期:2018-02-01 00:00:00
abstract::Cerebrospinal fluid levels of radioreceptor assayable insulin-like growth factors (RRA-IGFs) and immunoreactive somatomedin B (SMB) (RIA-B) were determined in apparently healthy individuals and in patients with dementia of the Alzheimer type (AD). The CSF levels of RIA-B and RRA-IGFs did not alter from the healthy con...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1988.tb05193.x
更新日期:1988-06-01 00:00:00
abstract::One of the aims of the European Study on Parasuicide, which was initiated by the Regional Office for the European Region of the World Health Organization in the mid-1980s, was to try to identify social and personal characteristics that are predictive of future suicidal behaviour. A follow-up interview study (the Repet...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1600-0447.1997.tb00378.x
更新日期:1997-02-01 00:00:00
abstract:OBJECTIVE:Post-traumatic stress disorder (PTSD) is considered a multidimensional disorder, with distinct symptom clusters including re-experiencing, avoidance/numbing, hyperarousal, and most recently depersonalization/derealization. However, the extent of differing intrinsic network connectivity underlying these sympto...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/acps.12387
更新日期:2015-07-01 00:00:00
abstract::For patients dependent on benzodiazepines alone, or in combination with alcohol and/or other legal and illegal drugs, observed mortality rates were compared with the average population, and, in cases of isolated benzodiazepine dependence, also with a control group of non-dependent patients chosen to match each depende...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1986.tb02693.x
更新日期:1986-03-01 00:00:00
abstract:OBJECTIVE:The study aimed to increase the knowledge about the detailed course differences between different forms of bipolar disorder. METHOD:Using the prospective life-chart-clinician version, we compared the fine-grain analysis of mood swings and treatment modalities of 18 bipolar II with 31 bipolar I patients. RES...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.2009.01412.x
更新日期:2009-12-01 00:00:00
abstract:OBJECTIVE:Ginseng root extract is a widely used herbal product not devoid of side effects. This report describes the development of manic symptoms after ginseng consumption in a patient with affective disorder. Other potentially harmful side effects of ginseng are also reviewed. METHOD:A single case report. RESULTS:A...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract::A group of 59 depressive in- and outpatients displayed statistically significantly subnormal electrodermal activity (EDA) according to the skin conductance level, the skin conductance response magnitude, the skin conductance response rate, and the index of nonresponding during neutral tone stimulation, compared to 59 ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1987.tb02940.x
更新日期:1987-12-01 00:00:00
abstract:OBJECTIVES:To differentiate the relation between the structure and timing of rest-activity patterns and symptoms of impulsivity and mood instability in bipolar disorder (BD), borderline personality disorder (BPD) and healthy controls (HC). METHODS:Eighty-seven participants (31 BD, 21 BPD and 35 HC) underwent actigraph...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/acps.13148
更新日期:2020-04-01 00:00:00
abstract::This investigation studied by direct interviews in a randomly selected sample of 58 Swedish unbroken families, factors of importance for the father's experience of his preschool child. The father's experience of his child was shown to correlate with the child's experience of him. Fathers experiencing their child in a ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1980.tb00563.x
更新日期:1980-01-01 00:00:00