Nature of the genetic contribution to psychotic illness--a continuum viewpoint.

Abstract:

:The recurrent psychoses, rather than, as Kraepelin supposed, constituting 2 major entities, manic depressive illness and schizophrenia, as separate diseases, may be distributed along a continuum that extends from unipolar depressive illness through bipolar and schizoaffective psychosis to schizophrenia with increasing severities of defect state. It is proposed that this continuum rests on a genetic base, variations in the form of the gene accounting for variations in form of psychosis. The simplest interpretation of the continuum is that such variation relates to changes at a single genetic locus. Evidence from a postmortem study of brain structure in schizophrenia suggests that this is the gene that determines the development of asymmetries in the human brain, i.e., the cerebral dominance gene or right shift factor of Annett; a possible genomic location is in the pseudoautosomal region of the sex chromosomes.

journal_name

Acta Psychiatr Scand

authors

Crow TJ

doi

10.1111/j.1600-0447.1990.tb05471.x

subject

Has Abstract

pub_date

1990-05-01 00:00:00

pages

401-8

issue

5

eissn

0001-690X

issn

1600-0447

journal_volume

81

pub_type

杂志文章,评审
  • Can subsyndromal manifestations of major depression be identified in children at risk?

    abstract:OBJECTIVE:Children of parents with major depression are at significantly increased risk for developing major depression themselves; however, not all children at genetic risk will develop major depressive disorder (MDD). We investigated the utility of subsyndromal scores on the Child Behavior Checklist (CBCL) Anxiety/De...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/acps.12660

    authors: Uchida M,Fitzgerald M,Lin K,Carrellas N,Woodworth H,Biederman J

    更新日期:2017-02-01 00:00:00

  • Ecological correlates of suicide in the United States and Hungary.

    abstract::Ecological correlates of suicide were explored for the counties of Hungary and the states of the United States. Only one common correlate was identified (divorce rates). The remaining social indicators that were associated with suicide rates in the United States were not associated with suicide rates in Hungary. The i...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1989.tb10293.x

    authors: Lester D,Moksony F

    更新日期:1989-05-01 00:00:00

  • SCL-25 and recognition of mental disorders reported by primary health care physicians.

    abstract::A marked proportion of primary care patients have mental disorders and problems that remain unrecognized by the patients and their general practitioners. There is furthermore a great variation in the physicians' ability to detect mental disorders. The aim of the present study was to find out the overall prevalence of ...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1994.tb01522.x

    authors: Joukamaa M,Lehtinen V,Karlsson H,Rouhe E

    更新日期:1994-05-01 00:00:00

  • Personality and self-variables: important determinants of subjective quality of life in schizophrenia out-patients.

    abstract:OBJECTIVE:To investigate factors determining severely mentally ill patients' self-rated quality of life. The study hypothesized that objective life circumstances, personality, self-variables, and psychopathology would be determinants of quality of life. METHOD:A total of 117 individuals with schizophrenia and related ...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0447.2003.00103.x

    authors: Eklund M,Bäckström M,Hansson L

    更新日期:2003-08-01 00:00:00

  • The Reactivity of Psychosis Rating Form (RPRF): background, development and psychometrics.

    abstract::The ICD-10 and DSM-IV classifications have both given low priority to "reactivity" to acute stress as a classificatory principle for functional psychoses. In Scandinavia, reactivity is still considered an important factor in the development of such psychoses. Reactivity is a complex concept, and its various components...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章,多中心研究

    doi:10.1111/j.1600-0447.1996.tb09811.x

    authors: Guldberg CA,Dahl AA,Bertelsen A,Hansen H,Haslerud J,Hytten K,Narud K

    更新日期:1996-02-01 00:00:00

  • Selective serotonin reuptake inhibitors and violence: a review of the available evidence.

    abstract:OBJECTIVE:To provide a clinically useful analysis of the relationship between selective serotonin reuptake inhibitors (SSRIs), in particular fluoxetine and violent or suicidal behaviour. METHOD:All published papers on Medline and other databases linking serotonin, SSRIs and aggression were reviewed. RESULTS:A small p...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.1034/j.1600-0447.2001.00357.x

    authors: Walsh MT,Dinan TG

    更新日期:2001-08-01 00:00:00

  • Comparison between the Brief Psychiatric Rating Scale and the Manchester Scale for the rating of schizophrenic symptoms.

    abstract::A reliability study was carried out to compare the short Manchester Scale (MS) to the longer Brief Psychiatric Rating Scale (BPRS), to see if similar items scored the same aspect of pathology and to find the sources of error. The raters were a psychiatrist and a psychologist cum medical student; they had recently arri...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1986.tb06285.x

    authors: Manchanda R,Saupe R,Hirsch SR

    更新日期:1986-12-01 00:00:00

  • Social class and psychotherapy.

    abstract::By means of a psychiatric case register the total psychiatric population in the Nacka region (75,000 inhabitants) was analysed during a 2-year period with regard to the amount of psychotherapy consumed in different social groups. Among the patients, the utilization of psychotherapy was 60% for social group I compared ...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1983.tb07014.x

    authors: Cullberg J,Stefansson CG

    更新日期:1983-11-01 00:00:00

  • Gray matter volume alterations related to trait dissociation in PTSD and traumatized controls.

    abstract:OBJECTIVE:This study used voxel-based morphometry (VBM) to investigate brain structural alterations related to trait dissociation and its relationship with post-traumatic stress disorder (PTSD). METHOD:Thirty-two subjects either developing (N = 15) or non-developing (N = 17) PTSD underwent MRI scanning and were assess...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/acps.12026

    authors: Nardo D,Högberg G,Lanius RA,Jacobsson H,Jonsson C,Hällström T,Pagani M

    更新日期:2013-09-01 00:00:00

  • A two-phase, double-blind randomized study of three haloperidol plasma levels for acute psychosis with reassignment of initial non-responders.

    abstract::To clarify the plasma level/therapeutic response relationship of haloperidol (HPDL) we used a prospective double-blind design in 95 acutely psychotic patients. After drug washout, patients were randomly assigned to a low, middle or high plasma level range for 2 weeks (phase A), and then 50% of the initial non-responde...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1600-0447.1997.tb09642.x

    authors: Janicak PG,Javaid JI,Sharma RP,Leach A,Dowd S,Davis JM

    更新日期:1997-04-01 00:00:00

  • Suicide, homicide and the quality of life in various countries.

    abstract::Based on the theory of Henry & Short, it was predicted that suicide rates should be higher and homicide rates lower in countries where the quality of life is better. In 1980, for a sample of 43 countries, this prediction was confirmed for some components of the quality of life (psychological well-being) but not for ot...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1990.tb05459.x

    authors: Lester D

    更新日期:1990-04-01 00:00:00

  • Exploratory behavior in patients suffering from senile dementia: a comparison with children.

    abstract::Thirty-seven patients with the diagnosis of senile dementia and 70 children aged 6 months to 4 years were observed in three tasks that stimulated exploratory behavior. The subjects were rated according to the frequencies of certain forms of behavior in 52 variables. It was assumed that certain behavior would be more f...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:

    authors: Jonsson CO,Edin P,Söderberg S,Waldton S

    更新日期:1976-04-01 00:00:00

  • Treatment of vaginismus by i.v. diazepam (Valium) abreaction interviews.

    abstract::A new method of treatment of vaginismus by using intravenous diazepam abreaction interviews is reported. Four patients between the ages of 19 and 28 were interviewed. The duration of their main complaint varied from 6 months to 3 years. Three to six abreaction interviews were conducted; the maximum dosage of Valium us...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1976.tb00080.x

    authors: Mikhail AR

    更新日期:1976-05-01 00:00:00

  • Co-occurrence of Axis I and Axis II disorders in substance abusers.

    abstract:OBJECTIVE:This study examined the co-occurrence of anxiety/mood and personality disorders (PDs) in substance abusers, the impact of anxiety/ mood disorders on the symptom profiles of PDs, and the impact of anxiety/mood disorders and PDs on pre-treatment status. METHOD:Current anxiety/mood disorders and PDs and pre-tre...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0447.2000.90050.x

    authors: Verheul R,Kranzler HR,Poling J,Tennen H,Ball S,Rounsaville BJ

    更新日期:2000-02-01 00:00:00

  • Psychiatric care of refugees exposed to organized violence. A comparative study of refugees and immigrants in Frederiksborg County, Denmark.

    abstract::Psychiatry in Scandinavia has a tradition for research and clinical work with people from other countries, especially related to refugees and survivors after the Second World War. In recent years an increasing number of refugees have arrived, especially from the countries of the Middle East. The aim of this study was ...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1989.tb01313.x

    authors: Jensen SB,Schaumburg E,Leroy B,Larsen BO,Thorup M

    更新日期:1989-08-01 00:00:00

  • Evaluation and interpretation of symptom structures in patients with schizophrenia.

    abstract::Seventy Japanese DSM-III-R schizophrenic patients were assessed for 30 clinical symptoms using the Positive and Negative Syndrome Scale (PANSS) of Kay et al. Principal component analysis was applied to the full item set of this scale and disclosed 5 orthogonal independent symptom groups: negative, hostile/excited, tho...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1994.tb01536.x

    authors: Kawasaki Y,Maeda Y,Sakai N,Higashima M,Urata K,Yamaguchi N,Kurachi M

    更新日期:1994-06-01 00:00:00

  • Patterns of overt sexual interaction among acute psychiatric inpatients.

    abstract::An indepth study was carried out over 1 year on all instances of overt heterosexual interactions among acute psychiatric patients on mixed-sex intensive treatment units. Sixteen of the 1060 patients treated on the units were involved in nine instances of overt heterosexual interactions. Analysis of the interactions sh...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1981.tb00804.x

    authors: Modestin J

    更新日期:1981-11-01 00:00:00

  • White matter maturation during 12 months in individuals at ultra-high-risk for psychosis.

    abstract:OBJECTIVE:The neurodevelopmental hypothesis of psychosis suggests that disrupted white matter (WM) maturation underlies disease onset. In this longitudinal study, we investigated WM connectivity and compared WM changes between individuals at ultra-high-risk for psychosis (UHR) and healthy controls (HCs). METHOD:Thirty...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/acps.12835

    authors: Krakauer K,Nordentoft M,Glenthøj BY,Raghava JM,Nordholm D,Randers L,Glenthøj LB,Ebdrup BH,Rostrup E

    更新日期:2018-01-01 00:00:00

  • Psychogenic pain: a study of marital adjustment.

    abstract::The marital adjustment of patients with psychogenic pain disorder was evaluated and compared with a matched group of patients with other neurotic disorders. Pain patients spouses were found to have better marital adjustment and less psychiatric morbidity than the spouses of neurotic patients. These findings are discus...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1987.tb02769.x

    authors: Hughes AM,Medley I,Turner GN,Bond MR

    更新日期:1987-02-01 00:00:00

  • Suicide in psychiatric patients. A prospective study of 67 cases without initial signs of severe depression or alcoholism.

    abstract::All cases from the county, who were subjected to post-mortem examination at the Department of Forensic Medicine, University of Lund with a diagnosis of suicide during 1949-1984, were compared with the inpatient register at the Department of Psychiatry, University Hospital, Lund during 1949-1969. During these years all...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1987.tb05628.x

    authors: Berglund M,Krantz P,Lundqvist G,Therup L

    更新日期:1987-10-01 00:00:00

  • Association between the antioxidant uric acid and depression and antidepressant medication use in 96 989 individuals.

    abstract:OBJECTIVE:In the last decade, several studies have suggested that depression is accompanied by increased oxidative stress and decreased antioxidant defenses. We tested the hypothesis that high levels of the antioxidant uric acid are associated with lower risk of hospitalization with depression and use of prescription a...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/acps.12793

    authors: Wium-Andersen MK,Kobylecki CJ,Afzal S,Nordestgaard BG

    更新日期:2017-10-01 00:00:00

  • The level of illicit drug use is related to symptoms and premorbid functioning in severe mental illness.

    abstract:OBJECTIVE:There is conflicting data on drug abuse and outcome in severe mental illness. This study aims to investigate if the amount of illicit psychoactive drug use is related to symptom load or premorbid functioning across diagnosis in patients with severe mental illness. METHOD:Symptom load, sociodemographic status...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.2008.01244.x

    authors: Ringen PA,Melle I,Birkenaes AB,Engh JA,Faerden A,Vaskinn A,Friis S,Opjordsmoen S,Andreassen OA

    更新日期:2008-10-01 00:00:00

  • Prejudice and schizophrenia: a review of the 'mental illness is an illness like any other' approach.

    abstract:OBJECTIVE:Many anti-stigma programmes use the 'mental illness is an illness like any other' approach. This review evaluates the effectiveness of this approach in relation to schizophrenia. METHOD:The academic literature was searched, via PsycINFO and MEDLINE, to identify peer-reviewed studies addressing whether public...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.1111/j.1600-0447.2006.00824.x

    authors: Read J,Haslam N,Sayce L,Davies E

    更新日期:2006-11-01 00:00:00

  • The influence of premenstrual syndrome on ratings of anxiety in women with generalized anxiety disorder.

    abstract::During the premenstrual and follicular phases of the menstrual cycle, 41 women who had generalized anxiety disorder (GAD) plus premenstrual syndrome (PMS) were assessed with psychiatric rating scales and compared with 21 GAD patients without PMS and 19 controls. The latter two groups were rated only once, in the typic...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1993.tb03451.x

    authors: McLeod DR,Hoehn-Saric R,Foster GV,Hipsley PA

    更新日期:1993-10-01 00:00:00

  • Selective serotonin reuptake inhibitor exposure during early pregnancy and the risk of birth defects.

    abstract:OBJECTIVE:To assess the methodological value of studies that signaled one or more selective serotonin reuptake inhibitors (SSRIs) as teratogenic agents. METHOD:Medical literature, published in English (1980-November 2010), was searched using MEDLINE/PubMed, TOXNET, EMBASE, and The Cochrane Library to identify all arti...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.1111/j.1600-0447.2011.01673.x

    authors: Gentile S

    更新日期:2011-04-01 00:00:00

  • The 10-year course of PTSD in borderline patients and axis II comparison subjects.

    abstract:OBJECTIVE:The first objective is to detail the prevalence of post-traumatic stress disorder (PTSD) over a decade of follow-up for those in both study groups. The second is to determine time-to-remission, recurrence, and new onset of PTSD, and the third is to assess the relationship between sexual adversity and the like...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.2011.01717.x

    authors: Zanarini MC,Hörz S,Frankenburg FR,Weingeroff J,Reich DB,Fitzmaurice G

    更新日期:2011-11-01 00:00:00

  • Non-suicidal self-injury and its co-occurrence with suicidal behavior: An epidemiological-study among adolescents and young adults.

    abstract:OBJECTIVE:Non-suicidal self-injury (NSSI) comprising thoughts and behaviors is common and often co-occurring with suicidal behavior like ideation, plan, and attempt. As limited data are available for adolescents and young adults, this study aims to present prevalence estimates for lifetime NSSI, its co-occurrence with ...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/acps.13237

    authors: Voss C,Hoyer J,Venz J,Pieper L,Beesdo-Baum K

    更新日期:2020-12-01 00:00:00

  • Adjustment reactions: a long-term prospective and retrospective follow-up of former patients in a crisis intervention ward.

    abstract::The results of a 5-year follow-up study of 76 patients in a crisis intervention ward who were suffering from an adjustment reaction (brief or prolonged depressive reaction) according to ICD-9 criteria indicate a rather favorable course and outcome using standardized instruments. Only 17% developed a chronic or severe ...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1991.tb01426.x

    authors: Bronisch T

    更新日期:1991-07-01 00:00:00

  • Cerebral dysfunction in alcoholism and presenile dementia. A comparison of two groups of patients with similar reduction of the cerebral blood flow.

    abstract::Fifteen chronic alcoholics and 15 presenile patients were matched in pairs with regard to their mean hemisphere cerebral blood parameters-an index of brain metabolism. The distribution of the regional cerebral blood flow was similar in the two groups. The alcoholics performed significantly better in all psychometric t...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0447.1977.tb00184.x

    authors: Berglund M,Gustafson L,Hagberg B,Ingvar DH,Nilsson L,Risberg J,Sonesson B

    更新日期:1977-05-01 00:00:00

  • Impact of childhood trauma on course of panic disorder: contribution of clinical and personality characteristics.

    abstract:OBJECTIVE:To investigate the impact of childhood trauma on the clinical course of panic disorder and possible contributing factors. METHOD:Longitudinal data of 539 participants with a current panic disorder were collected from the Netherlands Study of Depression and Anxiety (NESDA). Childhood trauma was assessed with ...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/acps.12726

    authors: De Venter M,Van Den Eede F,Pattyn T,Wouters K,Veltman DJ,Penninx BWJH,Sabbe BG

    更新日期:2017-06-01 00:00:00