Economic impact of antidepressant treatment duration in naturalistic conditions.

Abstract:

OBJECTIVE:To assess the economic impact of the duration of antidepressant drug treatment in a real-life setting. METHOD:A historical fixed cohort study included 27 917 patients aged 18 and over with a new antidepressant treatment registered in the national insurance database. The economic impact concerned healthcare expenditure in the first 3 months after treatment discontinuation. Generalized linear models were used to compare two groups of treatment duration: <6 months and 6 months and over. RESULTS:After adjustment for care costs before and during treatment episode, gender, age, chronic diseases, welfare and prescriber specialty, total healthcare costs (in log) [-0.06 (-0.14;0.01) P = 0.11] and psychiatric care costs (in square root) [-0.08 (-0.41;0.25) P = 0.6] were similar in both groups. Non-psychiatric care costs were significantly lower in the 'long treatment duration' group compared with the 'short treatment duration' group [-11.4 (-15.8; -7.0) P < 0.0001]. The decreases in total and non-psychiatric care costs over the antidepressant treatment episode were larger in the 'long treatment duration' group compared with the 'short treatment duration' group. CONCLUSION:With regard to healthcare costs and global health, antidepressant drug treatments of short duration appear less effective than treatment of recommended duration.

journal_name

Acta Psychiatr Scand

authors

Tournier M,Crott R,Gaudron Y,Verdoux H

doi

10.1111/acps.12035

subject

Has Abstract

pub_date

2013-05-01 00:00:00

pages

365-72

issue

5

eissn

0001-690X

issn

1600-0447

journal_volume

127

pub_type

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