Abstract:
OBJECTIVE:The aim of this study was to investigate the relationship between low cerebrospinal fluid 5-hydroxyindoleacetic acid (CSF 5-HIAA) and aggressive acts in mentally disordered violent offenders. METHOD:CSF concentrations of 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid and 4-hydroxy-3-methoxyphenyl glycol were measured in 35 drug-free men convicted of homicide and currently undergoing forensic psychiatric investigation in a high security hospital. RESULTS:The mean metabolite concentrations in the homicide offenders did not differ from those of age- and body-height matched male control subjects. One-third of the murderers had made one or several suicide attempts, and their mean concentration of spinal fluid 5-HIAA was significantly lower than that of the remaining murderers. Subjects with impulse control disorder also had lower mean CSF 5-HIAA. A consistent pattern of higher CSF 5-HIAA in subjects with more self-reported anxiety traits was observed. CONCLUSION:The association between serotonin and suicidal behaviour holds for yet another subject group. Determining CSF 5-HIAA might be worth while in the routine assessment of psychiatrically ill homicide offenders.
journal_name
Acta Psychiatr Scandjournal_title
Acta psychiatrica Scandinavicaauthors
Lidberg L,Belfrage H,Bertilsson L,Evenden MM,Asberg Mdoi
10.1034/j.1600-0447.2000.101005395.xsubject
Has Abstractpub_date
2000-05-01 00:00:00pages
395-402issue
5eissn
0001-690Xissn
1600-0447journal_volume
101pub_type
杂志文章abstract::As a part of the American-Danish prospective study of children of schizophrenic mothers, psychiatrically hospitalised and untreated cases of schizophrenia spectrum conditions, i.e. borderline schizophrenia, schizoid and paranoid personality disorders, were compared on a number of characteristics. This exploratory anal...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1987.tb02749.x
更新日期:1987-01-01 00:00:00
abstract:OBJECTIVE:To investigate the durability of positive effects of cognitive behaviour therapy (CBT) with coping training on psychotic symptoms and social functioning. METHOD:Forty patients with schizophrenia or related psychotic disorders and refractory auditory hallucinations were given CBT and coping training in an int...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1034/j.1600-0447.2001.00213.x
更新日期:2001-05-01 00:00:00
abstract::In recent discussions on euthanasia the question about mercy killing without consent of mentally ill persons has turned up, particularly in cases of hopeless suffering among senile or chronically insane patients. Possible analogies to the actions under the German Nazi-regimen and relations to the concept of Social Dar...
journal_title:Acta psychiatrica Scandinavica
pub_type: 历史文章,杂志文章
doi:10.1111/j.1600-0447.1982.tb00832.x
更新日期:1982-02-01 00:00:00
abstract:OBJECTIVE:We examine the safety and efficacy of venlafaxine monotherapy in bipolar type II (BP II) patients with major depressive episode (MDE) who were unresponsive to prior lithium monotherapy. We hypothesized that venlafaxine would be superior to lithium with a low hypomanic conversion rate. METHOD:Seventeen patien...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.2009.01462.x
更新日期:2010-03-01 00:00:00
abstract::The rates of middle ear disease in 70 patients with schizophrenia from a defined catchment population were compared with the rates in 359 nonpsychiatric controls who were matched for age, sex and general practice. A relative risk (odds ratio) of middle ear disease in schizophrenia of 1.92 was found. This was raised to...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1995.tb09771.x
更新日期:1995-04-01 00:00:00
abstract::Failure to respond to adequate pharmacological treatment for major depression is now the most common indication for the use of electroconvulsive therapy (ECT). The advantages of ECT with respect to both speed and quality of response are clinically important issues, but surprisingly few studies have examined the effica...
journal_title:Acta psychiatrica Scandinavica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1600-0447.1997.tb09926.x
更新日期:1997-11-01 00:00:00
abstract::Eleven patients with DSM-III-R major depression who were treatment-resistant to sertraline were allocated for lithium augmentation therapy. In conjunction with their sertraline, 6 received lithium carbonate 400 mg at night and 5 received 800 mg at night. A total of 7 patients responded within 1 week. The degree of res...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1993.tb03461.x
更新日期:1993-10-01 00:00:00
abstract::The psychopathological pattern of depression was assessed by means of the Puzyński Inventory Scale for Depression (ISD) in 79 patients with bipolar affective disorders, 45 with unipolar and 42 with undifferentiated type of affective disorders. Four groups of patients showing different psychopathological patterns were ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1986.tb10579.x
更新日期:1986-02-01 00:00:00
abstract:OBJECTIVE:Studies from three independent laboratories report varying relationships between electrodermal hyporeactivity and suicidal behavior in depressed patients. The aims of this study were to explain that variation, to assess the discriminative validity of electrodermal hyporeactivity for suicide and suicide attemp...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.2009.01364.x
更新日期:2009-05-01 00:00:00
abstract::The care of mentally ill people at home is being encouraged nowadays. As a result, the family members feel an increased burden of care and find it difficult to cope with the care of a schizophrenic patient at home. We interviewed the relatives of 62 schizophrenics systematically regarding the behaviour of the patients...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1992.tb03249.x
更新日期:1992-09-01 00:00:00
abstract::Based on the theory of Henry & Short, it was predicted that suicide rates should be higher and homicide rates lower in countries where the quality of life is better. In 1980, for a sample of 43 countries, this prediction was confirmed for some components of the quality of life (psychological well-being) but not for ot...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1990.tb05459.x
更新日期:1990-04-01 00:00:00
abstract:OBJECTIVE:To measure how primary care physicians (PCPs) and psychiatrists treat mild depression. METHOD:We surveyed a national sample of US PCPs and psychiatrists using a vignette of a 52-year-old man with depressive symptoms not meeting Major Depressive Episode criteria. Physicians were asked how likely they were to ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.2012.01887.x
更新日期:2012-11-01 00:00:00
abstract::Thirty-seven, out of a sample of 100 elderly subjects, all suffering from dementia, were found to have delusions. The delusions were more common in women, in patients with a history of psychiatric illness, and amongst those with higher information subscores (Blessed Scale); and were less common in patients suffering f...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1985.tb02610.x
更新日期:1985-09-01 00:00:00
abstract::A previous report by our group and results published by other research groups have indicated a dichotomy in MHPG levels in depressed patients. This study attempted to characterize phenomena associated with this dichotomy in plasma MHPG levels. First, we have noted, at least in female patients, that homogeneity of MHPG...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1989.tb03012.x
更新日期:1989-11-01 00:00:00
abstract::The leisure activities of 110 depressed patients and of 98 non-psychiatric controls were studied. The following aspects of leisure behaviour were taken into account: quantity, type (active, passive), frequency, presence of other people, place and satisfaction. In addition, possible relationships between personality an...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1984.tb04515.x
更新日期:1984-01-01 00:00:00
abstract:OBJECTIVE:To examine the risk factors for suicidal behaviour in human immunodeficiency virus (HIV) positive patients. METHOD:HIV substance dependent positive patients who had attempted suicide were compared with HIV substance dependent positive patients who had never attempted suicide for suicide risk factors. RESULT...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1034/j.1600-0447.2003.02033.x
更新日期:2003-01-01 00:00:00
abstract::Patients attending a clinic were ascertained for psychiatric morbidity by a general practitioner and reascertained by a psychiatrist. The agreement ranged from 84% for neurosis and 60% for psychosis. The differences were mainly due to a lack of the depression category in the general practitioner's classification. One ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1981.tb00784.x
更新日期:1981-10-01 00:00:00
abstract::302 mentally retarded adults, sampled by epidemiological criteria, were examined with regard to epilepsy and psychiatric disorder. Each of the complications was frequent and related to degree and origin of mental retardation. In 55 (18.2%) epilepsy had occurred at some time during their lives, in 25 (8.3%) of these in...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1985.tb02654.x
更新日期:1985-12-01 00:00:00
abstract:OBJECTIVE:To compare ratings of quality of life in patients with established schizophrenia in Chandigarh, India, in both subjective and objective view points and between patients' and relatives' ratings. METHOD:Subjective and objective quality of life was assessed in 38 patients with schizophrenia using the Quality of...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1034/j.1600-0447.2001.104001051.x
更新日期:2001-07-01 00:00:00
abstract::The possible hypersecretion involvement of corticotropin-releasing hormone (CRH) in the pathophysiology of hypothalamic-pituitary-adrenocortical axis disturbances in patients with major depressive episode and with an abnormal dexamethasone suppression test (DST) was investigated. The corticotropin (ACTH) and cortisol ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1993.tb03344.x
更新日期:1993-02-01 00:00:00
abstract::The purpose of this study was to determine whether (reported) parental over involvement and lack of affection identify initially healthy subjects at risk for depression. One thousand subjects from the province of Utrecht, the Netherlands were randomly selected by using telephone addresses and asked to participate in a...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1992.tb03265.x
更新日期:1992-10-01 00:00:00
abstract::The availability of confiding persons both within and outside the household has been investigated in a series of 110 depressed patients and of 98 non-psychiatric controls. The depressive sample has been classified into diagnostic subgroups of unipolar, bipolar, reactive-neurotic and unspecified type of depression. The...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1984.tb01194.x
更新日期:1984-08-01 00:00:00
abstract:OBJECTIVE:To examine the associations between the Rust Inventory of Schizotypal Cognitions (RISC) and psychotic symptoms measured by the Present State Examination (PSE) and to assess the predictive validity of the RISC for later onset of schizophrenia. METHOD:A total of 154 subjects at high risk for schizophrenia but ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1034/j.1600-0447.2002.1o175.x
更新日期:2002-05-01 00:00:00
abstract::Electrodermal activity and heart-rate were recorded in the laboratory from partially remitted schizophrenic patients living in the community, chronic schizophrenic inpatients and normal controls. Althoug all patients had faster heart-rates, no consistent electrodermal differences between patient groups and normals wer...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1978.tb06905.x
更新日期:1978-05-01 00:00:00
abstract::A total of 30 patients with newly diagnosed motor conversion disorder were consecutively investigated by means of a Swedish self-rating inventory designed to assess perceived parental rearing practices (EMBU), and the Karolinska Scale of Personality (KSP). DSM Axis I and II psychopathology was assessed using a Structu...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1998.tb10086.x
更新日期:1998-10-01 00:00:00
abstract:OBJECTIVE:To compare the service use and costs of individuals who have a dual diagnosis of psychosis and substance abuse with those who have a diagnosis of psychosis but no substance abuse. METHOD:Patients with psychosis were identified and a representative sample were interviewed. Six-month service use was measured a...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1034/j.1600-0447.2000.101006464.x
更新日期:2000-06-01 00:00:00
abstract::The ICD-10 and DSM-IV classifications have both given low priority to "reactivity" to acute stress as a classificatory principle for functional psychoses. In Scandinavia, reactivity is still considered an important factor in the development of such psychoses. Reactivity is a complex concept, and its various components...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1600-0447.1996.tb09811.x
更新日期:1996-02-01 00:00:00
abstract:OBJECTIVE:To review the evidence from empirical studies regarding the validity of 'post-traumatic stress disorder with secondary psychotic features' (PTSD-SP) as a separate diagnostic entity. METHOD:The authors performed a review tracing publications between 1980 and January 2008. RESULTS:Twenty-four comparative stud...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0447.2008.01252.x
更新日期:2009-01-01 00:00:00
abstract::The aim of this 12-week, double-blind, parallel group, placebo-controlled study was to compare paroxetine with clomipramine in 367 patients with DSM-III-R defined panic disorder. Efficacy assessments included the daily panic attack diary, the Clinical Global Impression Scale, the Hamilton Anxiety Rating Scale, the Mar...
journal_title:Acta psychiatrica Scandinavica
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1111/j.1600-0447.1997.tb00388.x
更新日期:1997-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the long-term effectiveness of the second generation antipsychotics, risperidone and olanzapine on hospitalization, clinical response, and adherence to therapy after switching from conventional antipsychotics or clozapine in a naturalistic setting of schizophrenic patients. METHOD:Data were regis...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1034/j.1600-0447.2003.00063.x
更新日期:2003-05-01 00:00:00