Abstract:
:The results of double blind trial in which 139 patients with primary depression were randomly assigned to either lofepramine (46), imipramine (48), or placebo (45) are discussed. After treatment with either active drug, lofepramine or imipramine, the clinical outcome was significantly greater than with placebo. No significant differences were found in clinical responses between lofepramine and imipramine. With regard to reported side effects, however, a statistically significant lower number of severe and/or moderate side effects were reported for the lofepramine group than for the imipramine group. In particular, for severe and/or moderate occurrences of dry mouth, the statistically significant lower incidence in favor of lofepramine is by almost a factor of 3 (8 lofepramine vs 21 imipramine patients).
journal_name
Acta Psychiatr Scandjournal_title
Acta psychiatrica Scandinavicaauthors
Feighner JP,Meridith CH,Dutt JE,Hendrickson GGdoi
10.1111/j.1600-0447.1982.tb00918.xsubject
Has Abstractpub_date
1982-08-01 00:00:00pages
100-8issue
2eissn
0001-690Xissn
1600-0447journal_volume
66pub_type
临床试验,杂志文章,随机对照试验abstract::Two groups of former depressed Italian patients comprising 54 bipolars and 52 unipolars completed the Italian version of the EMBU, a Swedish instrument aimed at assessing the experience of parental rearing behaviour. As in a previous study of Swedish depressives, three factors, "rejection", "emotional warmth", and "ov...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1985.tb02591.x
更新日期:1985-08-01 00:00:00
abstract::Of all neuroleptic-naive, acutely psychotic subjects admitted to hospital over a 2-year period (n = 62), 27 participated in a neuroendocrine study and 35 did not participate (51% refused consent, 19% were incapable of consent and 31% started neuroleptics immediately). However, all nonparticipants agreed to psychopatho...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1991.tb05558.x
更新日期:1991-05-01 00:00:00
abstract:OBJECTIVE:To review the evidence from empirical studies regarding the validity of 'post-traumatic stress disorder with secondary psychotic features' (PTSD-SP) as a separate diagnostic entity. METHOD:The authors performed a review tracing publications between 1980 and January 2008. RESULTS:Twenty-four comparative stud...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0447.2008.01252.x
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVE:To examine the association between physical and mental disorders and the separate and joint effect of physical and mental disorders on work-loss. METHOD:Data was derived from the Netherlands Mental Health Survey and Incidence Study. This was a general population study in which 7076 adults, aged between 18 an...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.2005.00513.x
更新日期:2005-06-01 00:00:00
abstract::A prospective 1-year study was conducted in 69 patients with affective disorder. Despite remission, there was a significant continued presence at each visit of major symptoms of mania and depression and of mean mood shift. Furthermore, sub-clinical affective symptoms, as determined by General Behavior Inventory self-r...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1987.tb02841.x
更新日期:1987-06-01 00:00:00
abstract:OBJECTIVE:Examine the overall incidence of medically treated depression in Denmark among individuals 15-44 years old, and estimate the 5-year cumulative incidence of psychiatric hospital care among individuals treated first in non-hospital-based care. METHODS:We followed all individuals born in Denmark between 1969 an...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/acps.13028
更新日期:2019-06-01 00:00:00
abstract::We conducted a 25-year follow-up study of 50 children of schizophrenic mothers, consisting of 25 children reared by their mothers and 25 children reared apart. The children's adult psychiatric status was evaluated in a 3-h structured interview employing a battery of syndrome check-lists and scales. A slightly higher i...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1997.tb09936.x
更新日期:1997-11-01 00:00:00
abstract:OBJECTIVE:The neurodevelopmental hypothesis of psychosis suggests that disrupted white matter (WM) maturation underlies disease onset. In this longitudinal study, we investigated WM connectivity and compared WM changes between individuals at ultra-high-risk for psychosis (UHR) and healthy controls (HCs). METHOD:Thirty...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/acps.12835
更新日期:2018-01-01 00:00:00
abstract::Recent interest in community care of schizophrenic patients has led to publication of a number of studies that deal with patients' rehabilitation in their families. Joint efforts of psychologists, psychiatrists and social workers have produced a number of techniques for collaboration with families of schizophrenic pat...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0447.1989.tb10262.x
更新日期:1989-04-01 00:00:00
abstract:INTRODUCTION:This paper reviews studies on outcomes of involuntary hospital admissions in general adult psychiatry, and predictors of outcomes. METHOD:Studies assessing observer-rated clinical change and self-rated outcomes were identified. Relevant databases were searched and authors were contacted. Studies were clas...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0447.2006.00823.x
更新日期:2006-10-01 00:00:00
abstract:OBJECTIVE:The main objective of this study was to assess the prevalence of common mental disorders in the Moroccan general population. METHOD:On a systematic representative randomized sample, the Moroccan Arabic version of the Mini International Neuropsychiatric Interview (MINI) was used to assess the prevalence of mo...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.2009.01431.x
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVE:Behaviour therapy with exposure and response prevention (ERP) or cognitive behavioural therapy (CBT) including ERP are considered the psychological treatments of choice for obsessive-compulsive disorder (OCD), but group CBT/ERP has received relatively little research attention in the treatment of OCD. The aim...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,meta分析,评审
doi:10.1111/j.1600-0447.2008.01270.x
更新日期:2009-02-01 00:00:00
abstract::This report examines the comorbidity among three key symptoms associated with suicidal intent, namely hopelessness, depression and unusual thinking. A total of 97 out-patients with suicidal thoughts were assessed using the Beck Hopelessness Scale, the anxious depression and unusual thinking factor scales of the Deroga...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1998.tb09978.x
更新日期:1998-02-01 00:00:00
abstract::The results of a 5-year follow-up study of 76 patients in a crisis intervention ward who were suffering from an adjustment reaction (brief or prolonged depressive reaction) according to ICD-9 criteria indicate a rather favorable course and outcome using standardized instruments. Only 17% developed a chronic or severe ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1991.tb01426.x
更新日期:1991-07-01 00:00:00
abstract:OBJECTIVE:Studies from three independent laboratories report varying relationships between electrodermal hyporeactivity and suicidal behavior in depressed patients. The aims of this study were to explain that variation, to assess the discriminative validity of electrodermal hyporeactivity for suicide and suicide attemp...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.2009.01364.x
更新日期:2009-05-01 00:00:00
abstract:OBJECTIVE:Somatizing patients often report cognitive complaints but neuropsychological research on somatization is scarce. We investigated somatizing patients for functioning in different cognitive domains. METHOD:Ten female patients with somatization disorder or undifferentiated somatoform disorder and 10 non-somatiz...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1034/j.1600-0447.2002.01445.x
更新日期:2002-12-01 00:00:00
abstract:OBJECTIVE:Chronically mentally ill patients in community mental health care report a better quality of life (QOL) than those in long-term hospital care, which suggests that the treatment setting per se influences their QOL. METHOD:In a region where both treatment settings are of a comparable high standard, we assessed...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1999.tb10835.x
更新日期:1999-08-01 00:00:00
abstract:OBJECTIVE:To identify trajectories of depressive symptoms in older community residents. METHOD:Depressive symptomatology, based on a modified Center for Epidemiological Studies-Depression scale, was obtained at years 0, 3, 6, and 10, in the Duke Established Populations for Epidemiologic Studies of the Elderly (n = 416...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.2011.01801.x
更新日期:2012-06-01 00:00:00
abstract::Services are intended to maintain patients in the community while improving the quality of their lives. The purpose of this study was to determine the extent to which psychiatric patients' diagnoses, levels of autonomy, objective living conditions and degree of service utilization are associated with their perceived q...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1994.tb01489.x
更新日期:1994-01-01 00:00:00
abstract::Antidepressants are ineffective in about 30% of patients with major depression. Some authors then advise treatment of non-responders with (non-tricyclic) more selective reuptake inhibitors. In a double-blind, partial crossover study, 71 patients were selected for treatment during 4 weeks with oxaprotiline and/or fluvo...
journal_title:Acta psychiatrica Scandinavica
pub_type: 临床试验,杂志文章
doi:10.1111/j.1600-0447.1988.tb06402.x
更新日期:1988-12-01 00:00:00
abstract:OBJECTIVE:This study assessed the manner in which insight influenced schizophrenic patients' evaluation of their objective life conditions and the concurrent validity between patients' and clinicians' assessments of patients' global quality of life. METHOD:Forty out-patients who fulfilled DSM-III-R criteria for schizo...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1999.tb00994.x
更新日期:1999-06-01 00:00:00
abstract::A modified version of the revised Personality Diagnostic Questionnaire (PDQ-R), based on DSM-III-R personality disorders (PD), was completed by 74 psychiatric patients. A factor analysis of the scores for each of the PD (i.e. of the number of positive DSM-III-R criteria for each of the PD) yielded 3 factors that defin...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1991.tb03194.x
更新日期:1991-12-01 00:00:00
abstract:OBJECTIVE:To describe the impact of tobacco, alcohol and cannabis on metabolic profile and cardiovascular risk in bipolar patients. METHOD:Naturalistic, cross-sectional, multicenter Spanish study. Current use of tobacco, alcohol and cannabis was determined based on patient self-reports. Metabolic syndrome was defined ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1111/j.1600-0447.2009.01498.x
更新日期:2010-06-01 00:00:00
abstract::109 killers, 38 nonviolent offenders and 54 community controls were compared on psychiatric diagnosis, the MMPI, Cattell 16 PF, IQ and clinical neurological results. Killers did not differ from nonviolent offenders on diagnosis or personality in general. Only higher MMPI Hysteria scale scores differentiated the killer...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1982.tb00930.x
更新日期:1982-09-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to analyse the cost-incidence of schizophrenia in two areas with widely differing health service systems. METHOD:The costs of patients with schizophrenia in the 3 years after the first service contact were evaluated (i) in an area (A) with fully developed mental health community prog...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1999.tb10876.x
更新日期:1999-11-01 00:00:00
abstract::A case of organic brain syndrome occurring in relation to psychological stress 2 years after a severe head injury is described. Treatment with haloperidol resulted only in slight improvement. A dramatic improvement was achieved with carbamazepine. ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1988.tb05136.x
更新日期:1988-03-01 00:00:00
abstract::Beck's Depression Inventory was administered in a study of all students aged 16-17 years in the first year of high school in a Swedish town, and was completed by 93% of them (n = 2270). Cronbach's reliability coefficient alpha was 0.89, and there were strong correlations between item scores and total scores. A diagnos...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1997.tb09632.x
更新日期:1997-04-01 00:00:00
abstract:OBJECTIVE:Electroconvulsive therapy (ECT) is a highly effective and well-tolerated therapy for severe and treatment-resistant depression. Cognitive side-effects are still feared by some patients and clinicians. Importantly, cognitive impairments are among the most disabling symptoms of depression itself. METHODS:Patie...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/acps.12652
更新日期:2016-12-01 00:00:00
abstract::All cases from the county, who were subjected to post-mortem examination at the Department of Forensic Medicine, University of Lund with a diagnosis of suicide during 1949-1984, were compared with the inpatient register at the Department of Psychiatry, University Hospital, Lund during 1949-1969. During these years all...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1987.tb05628.x
更新日期:1987-10-01 00:00:00
abstract::A number of recent research reports have reported significant relationships between seasonal mood change (seasonality) and personality. However, some of the results are difficult to interpret because of inherent methodological problems, the most important of which is the use of samples drawn from the southern as oppos...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1997.tb10143.x
更新日期:1997-06-01 00:00:00