Improvement in verbal memory performance in depressed in-patients after treatment with electroconvulsive therapy.


OBJECTIVE:Electroconvulsive therapy (ECT) is a highly effective and well-tolerated therapy for severe and treatment-resistant depression. Cognitive side-effects are still feared by some patients and clinicians. Importantly, cognitive impairments are among the most disabling symptoms of depression itself. METHODS:Patients suffering from a severe episode of depression were treated with either ECT or treatment as usual (TAU) in an in-patient setting. Matched healthy participants served as controls (HC). Verbal memory was tested with the California Verbal Learning Test (CVLT) before the specific treatment started (ECT = 15, TAU = 16, HC = 31) and 2 months after the last ECT session or 2 months after discharge respectively. RESULTS:Before the specific treatment started, depressed patients performed substantially worse compared with HC in total, short- and long-delay recall in the CVLT, while the ECT group showed the worst performance. More severely depressed patients showed worse performances in these measures. Intriguingly, verbal memory showed a significant improvement in ECT-treated patients, but not in the other groups. No differences between the groups were found at follow-up. CONCLUSION:Contrary to the widely feared assumption that ECT has long-term impact on memory functions, we found evidence that ECT is superior to TAU in improving verbal memory in depressed patients.


Acta Psychiatr Scand


Biedermann SV,Bumb JM,Demirakca T,Ende G,Sartorius A




Has Abstract


2016-12-01 00:00:00












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    abstract:OBJECTIVE:While findings are contradictory, many studies report that long Duration of Untreated Psychosis (DUP) correlates with poorer outcome in first episode psychosis. In an outcome study of first-episode psychosis, we compared the patients who refused to participate in a follow-along with those who consented to est...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章


    authors: Friis S,Melle I,Larsen TK,Haahr U,Johannessen JO,Simonsen E,Opjordsmoen S,Vaglum P,McGlashan TH

    更新日期:2004-10-01 00:00:00

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    abstract::The author describes a 22-year-old male who suffered from chronic severe Obsessive-Compulsive Neurosis (OCN) complicated by frequent depressive episodes. Administering the monoamine oxidase inhibitor phenelzine in high dosage led to complete alleviation of his depression in 10 weeks, and 3 weeks afterwards the OCN was...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章


    authors: Mahgoub OM

    更新日期:1987-02-01 00:00:00

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    abstract:OBJECTIVE:The neurodevelopmental hypothesis of psychosis suggests that disrupted white matter (WM) maturation underlies disease onset. In this longitudinal study, we investigated WM connectivity and compared WM changes between individuals at ultra-high-risk for psychosis (UHR) and healthy controls (HCs). METHOD:Thirty...

    journal_title:Acta psychiatrica Scandinavica

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    authors: Krakauer K,Nordentoft M,Glenthøj BY,Raghava JM,Nordholm D,Randers L,Glenthøj LB,Ebdrup BH,Rostrup E

    更新日期:2018-01-01 00:00:00

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    pub_type: 临床试验,杂志文章


    authors: McCreadie RG,Morrison D,Eccleston D,Gall RG,Loudon J,Mitchell MJ

    更新日期:1985-08-01 00:00:00

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    abstract::The prevailing theory that normal intelligence and mild mental retardation are determined by multiple additive genes is critically reviewed in the light of findings from recent population studies. Discrepancies between theoretical concepts and reported data are noted, particularly those concerning frequency of mild me...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章


    authors: Akesson HO

    更新日期:1986-07-01 00:00:00

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    authors: Bradley HA,Rucklidge JJ,Mulder RT

    更新日期:2017-01-01 00:00:00

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    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章


    authors: Robinson S,Rapaport-Bar-Sever M,Rapaport J

    更新日期:1994-04-01 00:00:00

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    abstract:OBJECTIVE:Electroconvulsive therapy (ECT)-induced hippocampal volume change (HVC) has been repeatedly described in recent years. The similar time course of HVC and ECT-related cognitive effects suggest a relation, that is to date, understudied. This study investigates whether HVC following ECT predicts the change in me...

    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章


    authors: Laroy M,Bouckaert F,Vansteelandt K,Obbels J,Dols A,Emsell L,Stek M,Vandenbulcke M,Sienaert P

    更新日期:2019-11-01 00:00:00

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    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章


    authors: Bogren LY

    更新日期:1983-07-01 00:00:00

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    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章


    authors: Strejilevich SA,Martino DJ,Murru A,Teitelbaum J,Fassi G,Marengo E,Igoa A,Colom F

    更新日期:2013-09-01 00:00:00

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    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章


    authors: Núñez LA,Gurpegui M

    更新日期:2002-03-01 00:00:00

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    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章,随机对照试验


    authors: Kulhara P,Chakrabarti S,Avasthi A,Sharma A,Sharma S

    更新日期:2009-06-01 00:00:00

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    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章


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    更新日期:1988-04-01 00:00:00

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    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章


    authors: Nilsson LV,Persson G

    更新日期:1984-06-01 00:00:00

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    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章


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    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验


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    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章


    authors: Chastang F,Rioux P,Dupont I,Baranger E,Kovess V,Zarifian E

    更新日期:1998-12-01 00:00:00

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    journal_title:Acta psychiatrica Scandinavica

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    更新日期:1987-07-01 00:00:00

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    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章


    authors: Huber TJ,Borsutzky M,Schneider U,Emrich HM

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    pub_type: 杂志文章


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    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章


    authors: Stordal KI,Mykletun A,Asbjørnsen A,Egeland J,Landrø NI,Roness A,Rund BR,Sundet KS,Lundervold AJ,Lund A

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    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章


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    journal_title:Acta psychiatrica Scandinavica

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    authors: Keks NA,Copolov DL,Mackie B,Stuart GW,Singh BS,McGorry PD,Coffey C

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    pub_type: 临床试验,杂志文章,随机对照试验


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    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章


    authors: Kelly TM,Mann JJ

    更新日期:1996-11-01 00:00:00

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    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章


    authors: Buist-Bouwman MA,de Graaf R,Vollebergh WA,Ormel J

    更新日期:2005-06-01 00:00:00

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    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章,meta分析


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    更新日期:2000-12-01 00:00:00

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    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章


    authors: Hwu HG,Yeh EK,Chang LY,Yeh YL

    更新日期:1986-04-01 00:00:00

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    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章


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    journal_title:Acta psychiatrica Scandinavica

    pub_type: 杂志文章


    authors: Rizzardo R,Rovea A,Magni G

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