Abstract:
:We tested whether overload of the two ventricles may be associated with a preponderance of interventricular septum in patients with high blood pressure. The rationale is that the septum is shared by the greater and lesser circulation and that in hypertension the latter shows the same qualitative hemodynamic alterations as the former. Among 65 hypertensive patients, 40 (group 1) showed (echo) posterior wall thickness within the mean +/- 1 SD of 62 normal subjects, and 25 (group 2) had a posterior wall thickness exceeding the mean + 1 SD of the normal population. Both groups were subdivided into subgroups A and B, which included patients whose ventricular septum was similar to (within the mean + 1 SD) and thicker than (exceeding the mean + 1 SD) the posterior wall thickness in the corresponding group, respectively. Resting differences in systemic and pulmonary pressure and vascular resistance among subgroups 1A, 1B, and 2A were not significant; however, in subgroup 2B these variables exceeded those in the other subgroups to a significant extent. During cold pressor testing (CPT) the levels reached and the changes in pressure and resistance from baseline values in both circuits were much greater in subgroups B than in subgroups A. The baseline plasma norepinephrine value showed a trend toward an increase from subgroup 1A to 1B and from subgroup 2A and 2B; during CPT norepinephrine invariably changed and in subgroups B it rose significantly more than in subgroups A. It was not determined whether this caused the hemodynamic overload in subgroups B.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
Am Heart Jjournal_title
American heart journalauthors
Fiorentini C,Galli C,Tamborini G,Moruzzi P,Berti M,Riva S,Guazzi MDdoi
10.1016/0002-8703(88)90626-6subject
Has Abstractpub_date
1988-08-01 00:00:00pages
509-14issue
2 Pt 1eissn
0002-8703issn
1097-6744pii
0002-8703(88)90626-6journal_volume
116pub_type
杂志文章abstract::A pair of endocardial pacemaker leads, identical except for the presence or absence of dexamethasone elution from the distal stimulating electrode, was implanted into the right ventricle of each of 12 dogs for either 3 weeks (n = six pairs) or 6 weeks (n = six pairs). Fibrous connective tissue sheaths (0.04 to 0.20 mm...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(89)90408-0
更新日期:1989-06-01 00:00:00
abstract:BACKGROUND:The objective was to report recent trends in the incidence, adoption of evidence-based treatment, and clinical outcomes for first-time hospitalization for acute myocardial infarction. METHODS:This is a large retrospective population-based cohort study using medical administrative data (International Classif...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2013.08.026
更新日期:2013-11-01 00:00:00
abstract::We investigated the relation between the angiographic collateral grade (Rentrop's classification) and the collateral flow velocity pattern in 43 patients with angina pectoris. Collateral flow velocity was measured with a Doppler guide wire during balloon occlusion in coronary angioplasty. Collateral flow was detected ...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(95)90232-5
更新日期:1995-07-01 00:00:00
abstract::The 2,000 heart donors available annually continue to be inadequate for the 50,000 patients with end-stage congestive heart failure who require heart transplantation to survive. This discrepancy has led to the successful use of long-term implantable LVADs as a bridge to transplantation and has raised the issue of perm...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(95)90056-x
更新日期:1995-01-01 00:00:00
abstract::A 17-year-old man with staphylococcal endocarditis of the mitral valve developed an infective aneurysm of the posterior left ventricular wall. Echocardiography revealed an echo-free space posterior to the posterior left ventricular wall. This echo-free space undoubtedly represented the aneurysmal sac, because it could...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(78)90051-0
更新日期:1978-09-01 00:00:00
abstract::Echocardiography was performed on 26 patients with prosthetic Björk-Shiley aortic valves (BSAV). Technically satisfactory records were obtained in 22 patients. The systolic displacement of the valve disc varied from 1 to 1.8 cm. (mean, 1.4 cm.). Six patients developed valve dysfunction. Two patients had complete absen...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(76)80215-3
更新日期:1976-03-01 00:00:00
abstract:UNLABELLED:Antiarrhythmic agents enhance maintenance of sinus rhythm (SR) after direct current cardioversion (DCC) for atrial fibrillation but there are few comparative trials. BACKGROUND:The aims of the study were (1) to establish whether patients successfully cardioverted to SR are more likely to stay in SR over 6 m...
journal_title:American heart journal
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ahj.2005.09.009
更新日期:2006-04-01 00:00:00
abstract::Quantitation of coronary luminal diameter with a 20 MHz mechanically rotating intravascular ultrasound (IVUS) catheter was compared with orthogonal-view cineangiography by use of a semiautomated edge-detection algorithm in 48 patients undergoing coronary angioplasty. Quantitative comparison of 196 matched segments was...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(94)90110-4
更新日期:1994-02-01 00:00:00
abstract::The hemodynamic, electrocardiographic, and metabolic responses of dogs with acute myocardial ischemia to intravenous administration of fructose-1,6-diphosphate (FDP) were assessed. Analysis of the results (compared to dextrose control) revealed evidence of major improvement of LVEDP and cardiac output, significant dec...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(80)90228-8
更新日期:1980-11-01 00:00:00
abstract:BACKGROUND:Statins are effective in the prevention of coronary events and the treatment of acute coronary syndromes. However, their efficacy and safety in patients with heart failure (HF) are unknown. In this review, we discuss the evidence for the efficacy and safety of statin therapy in patients with HF. METHODS:We ...
journal_title:American heart journal
pub_type: 杂志文章,评审
doi:10.1016/j.ahj.2005.09.008
更新日期:2006-07-01 00:00:00
abstract::Detection of mild hypertension by a small number of casual blood pressures may be inaccurate for the determination of average blood pressure. Nonetheless, casual pressures remain the basis for the diagnosis and treatment of hypertensive patients. We compared casual and noninvasive ambulatory blood pressure monitoring ...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(88)90180-9
更新日期:1988-10-01 00:00:00
abstract::We previously reported that single-head SPECT imaging with teboroxime is feasible. However, excessive hepatic uptake in some patients may interfere with image interpretation. This study examined the feasibility of improving image quality by use of a preprocessing masking technique to subtract hepatic activity. A band ...
journal_title:American heart journal
pub_type: 临床试验,杂志文章
doi:10.1016/0002-8703(92)90079-b
更新日期:1992-12-01 00:00:00
abstract:BACKGROUND:Current acetylsalicylic acid (ASA) dosing algorithms for the prevention of secondary thrombotic events in acute coronary syndrome (ACS) patients are inconsistent and lack sufficient data support. METHODS:We performed a systematic review of the literature for studies that assessed clinical outcomes in patien...
journal_title:American heart journal
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.ahj.2012.04.001
更新日期:2012-08-01 00:00:00
abstract::Although the Doppler mitral flow velocity pattern changes in accordance with the degree of left ventricular diastolic dysfunction, it is "normalized" in the presence of heart failure. In this study the pulmonary venous flow velocity pattern was characterized in 43 hypertensive patients with and without heart failure t...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(92)90982-2
更新日期:1992-10-01 00:00:00
abstract:BACKGROUND:Physical activity and symptom questionnaires have been used as surrogates for exercise testing to estimate a patient's functional capacity and to individualize an exercise testing protocol in accordance with exercise testing guidelines. To validate these approaches, they must be compared with measured oxygen...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1067/mhj.2001.118740
更新日期:2001-12-01 00:00:00
abstract::Infections related to cardiac surgery increase morbidity and mortality, and increase cost and use of health resources. With the widespread use of synthetic materials, whether in prosthetic valves or vascular conduits, bacterial infection and, more rarely, fungal complications can be devastating, requiring prolonged an...
journal_title:American heart journal
pub_type: 评论
doi:10.1016/j.ahj.2003.08.016
更新日期:2004-04-01 00:00:00
abstract:BACKGROUND:Little is known about the management of elderly patients with congestive heart failure (CHF) although they represent the majority of the CHF population. Therefore, the TIME-CHF study was set up (1) to evaluate the medical management of very old patients (> or = 75 years) with CHF compared with younger patien...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ahj.2005.10.022
更新日期:2006-05-01 00:00:00
abstract::Controlled-release drug delivery technology has had a significant effect on the pharmacotherapy of cardiovascular diseases. Oral and transcutaneous controlled-release systems allow relatively short-acting drugs to be administered once or twice daily with comparable therapeutic efficacy and fewer adverse reactions comp...
journal_title:American heart journal
pub_type: 杂志文章,评审
doi:10.1016/0002-8703(95)90019-5
更新日期:1995-02-01 00:00:00
abstract:BACKGROUND:In the United States as well as globally, Asians are a growing proportion of patients presenting with non-ST-segment elevation myocardial infarction (NSTEMI), yet little is known about their longitudinal outcomes. METHODS:We linked Centers for Medicare & Medicaid claims data to detailed clinical data for 37...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2013.10.001
更新日期:2013-12-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(84)90745-2
更新日期:1984-11-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章,评审
doi:10.1016/0002-8703(81)90738-9
更新日期:1981-09-01 00:00:00
abstract::Antiarrhythmic therapy for prevention of sustained ventricular tachycardia is commonly guided by programmed electrical stimulation, and the persistent ability to initiate ventricular tachycardia during drug therapy often leads to the use of nonpharmacologic therapies such as surgery. Prior studies suggest that program...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(05)80325-4
更新日期:1990-04-01 00:00:00
abstract::To evaluate regional differences in thickness and systolic function of human myocardium perfused by angiographically normal coronary arteries in valvular and ischemic heart disease, we performed intraoperative epicardial M-mode mapping of ventriculographically normal wall regions (perfused by normal coronary arteries)...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(86)90273-5
更新日期:1986-08-01 00:00:00
abstract::In a study of GTN absorption during exercise and high ambient temperature, 12 healthy volunteers carried 10 mg glyceryl trinitrate (GTN, nitroglycerin) transdermal patches for 6 hours during each of 3 days. During a control day the mean plasma GTN concentration ranged from 1.0 nmol/L (SD +/- 0.8 nmol/L) to 1.5 nmol/L ...
journal_title:American heart journal
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0002-8703(86)90518-1
更新日期:1986-09-01 00:00:00
abstract::Mitochondria in skeletal and cardiac muscle have been found to be less stable in aging hamsters, in contrast to preparations from young animals. We have found previously that clofibrate (Atromid-S) will reverse this degeneration in the older hamsters. This study examined the exercise tolerance of aged hamsters, to see...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(77)80040-9
更新日期:1977-10-01 00:00:00
abstract:BACKGROUND:Glycoprotein (GP) IIb/IIIa antagonists have become a mainstay for the treatment of acute coronary syndromes. Yet, they have rarely been evaluated under relevant pathophysiologic conditions, for example, high shear rates in the presence of physiologic calcium concentrations. We compared the efficacy of eptifi...
journal_title:American heart journal
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.ahj.2003.11.003
更新日期:2004-04-01 00:00:00
abstract::There has been considerable debate regarding the value of programmed electrical stimulation in patients who present with asymptomatic, or minimally symptomatic, nonsustained VT. Unfortunately, there has never been a sufficiently large study of an untreated group of patients to make any sense of the issue. We culled th...
journal_title:American heart journal
pub_type: 杂志文章,meta分析
doi:10.1016/0002-8703(92)90664-h
更新日期:1992-02-01 00:00:00
abstract:BACKGROUND:Depression is common in cardiac patients and has been associated with adverse clinical outcome. However, little is known about predictors of the onset of depressive symptoms. We examined predictors of the onset of depressive symptoms at 12 months post-percutaneous coronary intervention (PCI) in patients trea...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2005.08.012
更新日期:2006-02-01 00:00:00
abstract::In vitro studies have established that intravascular ultrasound is a reliable technique for accurate assessment of vascular anatomic structure and disease conditions before and after intervention. In addition, quantitative data from intravascular ultrasound studies correspond well with histologic findings, which serve...
journal_title:American heart journal
pub_type: 社论,评审
doi:10.1016/s0002-8703(96)90263-x
更新日期:1996-09-01 00:00:00
abstract:BACKGROUND:Angiotensin-converting enzyme inhibitors have been shown to attenuate adverse remodeling after acute myocardial infarction (AMI), and the same has been suggested for angiotensin II type 1 receptor antagonists in animal models. Therefore the aim of the study was to compare the effects of losartan and captopri...
journal_title:American heart journal
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.ahj.2003.10.031
更新日期:2004-03-01 00:00:00