Statin use in heart failure: a cause for concern?

abstract：OBJECTIVE:To assess whether serum uric acid, which is a marker of impaired oxidative metabolism, might correlate with left ventricular systolic and diastolic dysfunction in patients with chronic heart failure (CHF). BACKGROUND:Uric acid levels, which are frequently elevated in patients with CHF, correlate with leg vas...

journal_title：American heart journal

authors： Cicoira M,Zanolla L,Rossi A,Golia G,Franceschini L,Brighetti G,Zeni P,Zardini P

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:Moderate alcohol drinking and marine omega-3 fatty acids (omega3) have both been associated with low mortality from coronary heart disease (CHD). However, there is little data evaluating the interactions of wine ethanol drinking with omega3 in CHD patients. METHODS:The relationships between wine drinking an...

journal_title：American heart journal

authors： de Lorgeril M,Salen P,Martin JL,Boucher F,de Leiris J

更新日期：2008-01-01 00:00:00

abstract：:Our hypothesis was that the postoperative abnormalities in septal motion observed by M-mode echocardiography (MME) are due to changes of either ventricular shape or of total cardiac motion within the thorax. We obtained preoperative and early and late postoperative MME and two-dimensional echocardiograms on 25 patient...

journal_title：American heart journal

authors： Kerber RE,Litchfield R

更新日期：1982-08-01 00:00:00

abstract：BACKGROUND:Although there is evidence linking smoking and heart failure (HF), the association between lifetime smoking exposure and HF in older adults and the strength of this association among current and past smokers is not well known. METHODS:We examined the association between smoking status, pack-years of exposur...

journal_title：American heart journal

authors： Gopal DM,Kalogeropoulos AP,Georgiopoulou VV,Smith AL,Bauer DC,Newman AB,Kim L,Bibbins-Domingo K,Tindle H,Harris TB,Tang WW,Kritchevsky SB,Butler J

更新日期：2012-08-01 00:00:00

abstract：:Forty-four patients with atrial septal defects, aged 7 months to 18 years (median 8.9), underwent biplane transesophageal (TEE) and transthoracic (TTE) echocardiography. The size of the defect and the shunt flow volume were measured by TEE and compared with the actual size at surgery (N = 14) or the shunt volume measu...

journal_title：American heart journal

authors： Ishii M,Kato H,Inoue O,Takagi J,Maeno Y,Sugimura T,Miyake T,Kumate M,Kosuga K,Ohishi K

更新日期：1993-05-01 00:00:00

abstract：OBJECTIVE:The study aimed to determine the impact on eptifibatide-associated bleeding by implementing a computerized dosing algorithm in the cardiac catheterization suite. BACKGROUND:Excessive dosing of eptifibatide is associated with increased bleeding rates and hospital mortality. Although dosing adjustments based o...

journal_title：American heart journal

authors： Putney DR,Kleiman NS,Fromm RE Jr,Buergler JM

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Data derived from stress myocardial perfusion imaging (MPI) carry prognostic significance in young patients with hypertrophic cardiomyopathy (HCM), but there are limited data on the utility of stress MPI in patients with HCM who are older. This study examined the prognostic significance of stress MPI in an a...

journal_title：American heart journal

authors： Sorajja P,Chareonthaitawee P,Ommen SR,Miller TD,Hodge DO,Gibbons RJ

更新日期：2006-02-01 00:00:00

abstract：AIMS:Paclitaxel-eluting stents (PESs) have been shown to inhibit neointimal hyperplasia after percutaneous coronary intervention. Coroflex Please (B Braun, Melsungen, Germany) is a newly developed PES. We compared the clinical and angiographic efficacy of Coroflex Please with Taxus Liberte (Boston Scientific, Natick, M...

journal_title：American heart journal

authors： Seo JB,Kang SH,Hur SH,Park KW,Youn TJ,Park JS,Yang HM,Lee HY,Kang HJ,Koo BK,Bae JH,Kim SW,Moon KW,Choi JW,Lee SG,Chung WY,Kim SJ,Kim DI,Kim BO,Hyon MS,Park KS,Cha TJ,Yoo CW,Jeon HK,Kim HS

更新日期：2013-05-01 00:00:00

abstract：:We studied the possibility that a mitral regurgitant Doppler signal area on a two-dimensional color Doppler echocardiogram can reflect changes in mitral regurgitant volume in 24 patients with several types of mitral regurgitation. In 20 patients, mitral regurgitant Doppler signal areas were clear enough to measure. In...

journal_title：American heart journal

authors： Otsuji Y,Tei C,Kisanuki A,Natsugoe K,Kawazoe Y

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:Relationships between long-term use and level of dual antiplatelet therapy and outcomes after drug-eluting stent implantation are not well established. METHODS:This is a retrospective cohort study of 9,256 patients receiving drug-eluting stents between January 2003 and August 2006. We classified patients ac...

journal_title：American heart journal

authors： Petersen JL,Barron JJ,Hammill BG,Cziraky MJ,Anstrom KJ,Wahl PM,Eisenstein EL,Krucoff MW,Califf RM,Schulman KA,Curtis LH

更新日期：2010-03-01 00:00:00

abstract：:Doxazosin, a selective alpha 1-inhibitor, was assessed for antihypertensive efficacy, effect on lipid parameters, and safety profile in 21 hypertensive patients with noninsulin-dependent diabetes mellitus. The study involved a 2- to 4-week baseline period, a 10-week period in which patients received doxazosin, 1 to 8 ...

journal_title：American heart journal

authors： Castrignano R,D'Angelo A,Pati T,Al Awady M,Tronca R,Crepaldi G

更新日期：1988-12-01 00:00:00

abstract：:The effects of amiodarone on delayed afterdepolarization (DAD) and triggered automaticity induced by low potassium (0.5 mEq/L) were evaluated on isolated rabbit right ventricular muscles, by means of standard microelectrode techniques. Triggered automaticity was induced in 6 of 10 muscles in the control group, in four...

journal_title：American heart journal

authors： Ohta M,Karagueuzian HS,Mandel WJ,Peter T

更新日期：1987-02-01 00:00:00

abstract：:Cost-effectiveness analyses are routinely performed to determine whether the additional cost of a novel therapy is balanced by additional effectiveness. The definitions of costs and effects involve a variety of assumptions, both in general economic terms and with regard to the specific medical setting under considerat...

journal_title：American heart journal

authors： van Hout BA,Bowman L,Zelinger DJ,Simoons ML

更新日期：1998-04-01 00:00:00

abstract：OBJECTIVE:The aim of this study is to examine ethnic differences in depressive symptoms and antidepressant treatment in a cohort of patients undergoing diagnostic coronary angiography. BACKGROUND:Coronary heart disease (CHD) is the leading cause of mortality in the United States, with an excess of mortality in African...

journal_title：American heart journal

authors： Waldman SV,Blumenthal JA,Babyak MA,Sherwood A,Sketch M,Davidson J,Watkins LL

更新日期：2009-01-01 00:00:00

abstract：:Percutaneous transluminal coronary angioplasty (PTCA) has, in general, been restricted to therapy for patients with angina pectoris. Thrombolytic therapy and guide wire recanalization have been used to recanalize coronary arteries in patients with evolving myocardial infarction. Recently we and others have examined th...

journal_title：American heart journal

authors： Pepine CJ,Prida X,Hill JA,Feldman RL,Conti CR

更新日期：1984-04-01 00:00:00

abstract：:The clinical profile and outcome of idiopathic restrictive cardiomyopathy in a group of eight children are reviewed. There were six girls and two boys. Age at presentation was 4.0 +/- 2.6 years (range 1.3 to 9.5 years). All patients had evidence of congestive heart failure with systemic venous congestion. Right or lef...

journal_title：American heart journal

authors： Lewis AB

更新日期：1992-06-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to estimate the cost-effectiveness of beta-blocker therapy with either metoprolol or carvedilol in addition to conventional therapy for patients with heart failure (HF) in Canada. DESIGN:A Markov simulation was used to estimate the costs and life expectancy for treating patients...

journal_title：American heart journal

authors： Levy AR,Briggs AH,Demers C,O'Brien BJ

更新日期：2001-09-01 00:00:00

abstract：:Economic assessment can be incorporated into clinical trials to evaluate and compare the costs and benefits of different health care programs. In this article the three main types of evaluation are discussed: cost-effectiveness analysis, cost-utility analysis, and cost-benefit analysis. The measurement of direct and i...

journal_title：American heart journal

authors： Bulpitt CJ,Fletcher AE

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:Recent randomized clinical trials have suggested a benefit of an invasive management strategy in patients with acute coronary syndromes. However, the broader use and impact of the invasive management approach has not been established for patients with acute coronary syndromes beyond the relatively narrow pat...

journal_title：American heart journal

authors： Dauerman HL,Yarzebski J,Gore JM,Lessard D,Goldberg RJ

更新日期：2002-06-01 00:00:00

abstract：:Functional, ambulatory, community-dwelling subjects (n = 423, aged 75 to 85 years) underwent baseline 24-hour ambulatory electrocardiography (ECG) examinations as part of the Bronx Aging Study, a 10-year prospective cohort study designed to identify risk factors and disease markers for cardiovascular, cerebrovascular,...

journal_title：American heart journal

authors： Frishman WH,Heiman M,Karpenos A,Ooi WL,Mitzner A,Goldkorn R,Greenberg S

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND:No-reflow after primary percutaneous coronary intervention (PCI) in ST-elevation myocardial infarction (STEMI) is associated with poor prognosis. Endothelin-1 (ET-1) is a potent endothelium-derived vasoconstrictor that might aggravate reperfusion injury. The aim of our study was to assess the relationship be...

journal_title：American heart journal

authors： Eitel I,Nowak M,Stehl C,Adams V,Fuernau G,Hildebrand L,Desch S,Schuler G,Thiele H

更新日期：2010-05-01 00:00:00

abstract：:An expression representative of the rate of change of ventricular power during ejection was derived. The primary advantages of the expression are its theoretical value and its ability to characterize ventricular performance. The rate of change of ventricular power, measured during ejection, is virtually free of assump...

journal_title：American heart journal

authors： Stein PD,Sabbah HN

更新日期：1976-02-01 00:00:00

abstract：BACKGROUND:While pharmacologic stress single photon emission computed tomography myocardial perfusion imaging (SPECT-MPI) is used for noninvasive evaluation of patients who are unable to perform treadmill exercise, its impact on net reclassification improvement (NRI) of prognosis is unknown. METHODS:We evaluated the p...

journal_title：American heart journal

authors： Lee DS,Husain M,Wang X,Austin PC,Iwanochko RM

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Gastrointestinal bleeding (GIB) after percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS) and coronary artery disease (CAD) is associated with high morbidity and mortality. METHODS:The NIS database from 1998 to 2006 was used to identify 1,216,759 PCIs performed for ACS and CAD. We sou...

journal_title：American heart journal

authors： Shivaraju A,Patel V,Fonarow GC,Xie H,Shroff AR,Vidovich MI

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:A shortcoming of the pediatric electrocardiogram (ECG) appears to be its inability to accurately detect left ventricular hypertrophy (LVH). This study prospectively assesses the usefulness of the pediatric ECG as a screening modality for LVH. METHODS:Concomitant echocardiograms and ECGs from a large cohort ...

journal_title：American heart journal

authors： Rivenes SM,Colan SD,Easley KA,Kaplan S,Jenkins KJ,Khan MN,Lai WW,Lipshultz SE,Moodie DS,Starc TJ,Sopko G,Zhang W,Bricker JT,Pediatric Pulmonary and Cardiovascular Complications of Vertically Transmitted HIV Infection Study Grou

更新日期：2003-04-01 00:00:00

abstract：:Studies were conducted in 15 patients with coronary artery disease to determine if the type of pacing used to induce an extrasystole had a bearing on subsequent postextrasystolic potentiation (PESP) and if the fact that these were evaluated in jeopardized or nonjeopardized portions of the ventricle altered the ability...

journal_title：American heart journal

authors： Cooper MW,Lutherer LO,Stanton MW,Lust RM Jr

更新日期：1986-02-01 00:00:00

abstract：BACKGROUND:Chronotropic incompetence and left ventricular (LV) dilatation have both been shown to be markers of an adverse cardiovascular prognosis. Chronotropic incompetence has been described in patients with symptomatic LV dilatation and dysfunction, but the effect of asymptomatic LV dilatation and hypertrophy on ex...

journal_title：American heart journal

authors： Lauer MS,Larson MG,Evans JC,Levy D

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:Patients with unstable angina (UA) and non-ST-elevation myocardial infarction (NSTEMI) remain at risk for death and cardiac ischemic events after being discharged from the hospital. METHODS:We examined whether the Thrombolysis In Myocardial Infarction (TIMI) risk score for UA/NSTEMI, ascertained at presenta...

journal_title：American heart journal

authors： Sabatine MS,McCabe CH,Morrow DA,Giugliano RP,de Lemos JA,Cohen M,Antman EM,Braunwald E

更新日期：2002-06-01 00:00:00

abstract：:Coronary arterial stenosis of varying severity and length were created in open-chest dogs. The reactive hyperemic responses (RHR) to 15 second occlusions were used to produce flow increases and judge the physiological significance of the narrowings. RHR are sensitive indices of functional impairment when resting flow ...

journal_title：American heart journal

authors： Hillis WS,Friesinger GC

更新日期：1976-12-01 00:00:00

abstract：:Controlled versus uncontrolled reperfusion of ischemic myocardium after experimental coronary artery occlusion was studied to determine the effect on regional ventricular wall motion and associated biochemical alterations. Fourteen pigs underwent coronary artery occlusion for 1 hour followed by 2 hours of reperfusion....

journal_title：American heart journal

authors： Peng CF,Murphy ML,Colwell K,Straub KD

更新日期：1989-03-01 00:00:00