当前位置： SCI文献检索 > AMERICAN HEART JOURNAL期刊下所有文献 > Prognostic utility of single-photon emission computed tomography in adult patients with hypertrophic cardiomyopathy.

Prognostic utility of single-photon emission computed tomography in adult patients with hypertrophic cardiomyopathy.

Abstract：

BACKGROUND:Data derived from stress myocardial perfusion imaging (MPI) carry prognostic significance in young patients with hypertrophic cardiomyopathy (HCM), but there are limited data on the utility of stress MPI in patients with HCM who are older. This study examined the prognostic significance of stress MPI in an adult population of patients with HCM. METHODS:We examined 158 patients with HCM (aged 60 +/- 16 years, 61% men) who underwent exercise or pharmacologic stress MPI. Summed stress score (SSS, normal = 56) and summed reversibility scores were calculated for each patient. Follow-up was complete in 157 (99%) patients at a median duration of 5.2 years. RESULTS:Normal single-photon emission computed tomography (SPECT) images were present in 38% of the population. Summed stress score (P = .01) and summed reversibility score (P = .03) were both significantly associated with cardiovascular death. Survival at 10 years was significantly better in those with normal versus abnormal SPECT (89% vs 67%, P = .04). Ten-year survival also was better in those without versus those with ischemia (90% vs 64%, P = .02). Five-year survival could be stratified by SSS risk categories: low risk (SSS > or = 53), 97%; intermediate risk (SSS = 48-52), 94%; and high risk (SSS < or = 47), 79% (P = .04). Bivariate models of SSS and other significant covariates supported an independent relation of SSS to cardiovascular death. CONCLUSIONS:In an older population of patients with HCM referred for SPECT imaging, abnormal stress MPI identifies those at increased risk of cardiovascular death.

journal_name

Am Heart J

journal_title

American heart journal

authors

Sorajja P,Chareonthaitawee P,Ommen SR,Miller TD,Hodge DO,Gibbons RJ

doi

10.1016/j.ahj.2005.02.050

subject

Has Abstract

pub_date

2006-02-01 00:00:00

pages

426-35

issue

2

eissn

0002-8703

issn

1097-6744

pii

S0002-8703(05)00412-6

journal_volume

151

pub_type

杂志文章

相关文献

AMERICAN HEART JOURNAL文献大全
  • Coronary angioplasty in symptomatic patients after bypass surgery.

    abstract：:With the availability of percutaneous transluminal coronary angioplasty (PTCA), the management of patients who present with recurrent angina following coronary artery bypass surgery (CABG) has changed. From January 1987 to December 1988, 149 symptomatic post CABG patients underwent coronary angiography at our institut...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(90)90121-d

    authors： Tabbalat RA,Haft JI

    更新日期：1990-11-01 00:00:00

  • Erythropoietin improves anemia exercise tolerance and renal function and reduces B-type natriuretic peptide and hospitalization in patients with heart failure and anemia.

    abstract：BACKGROUND:Anemia is now recognized as being a common finding in CHF and is associated with increased mortality and morbidity. However, it is uncertain whether the anemia is actually causing the worse prognosis or is merely a marker of more severe cardiac disease. Previous intervention studies with subcutaneous (s.c.) ...

    journal_title：American heart journal

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.ahj.2006.08.005

    authors： Palazzuoli A,Silverberg D,Iovine F,Capobianco S,Giannotti G,Calabrò A,Campagna SM,Nuti R

    更新日期：2006-12-01 00:00:00

  • Circadian variation and triggering of acute coronary events.

    abstract：:The recognition that the onset of cardiovascular events follows a circadian periodicity and is frequently triggered by physical or mental stresses has created new possibilities for disease prevention. Morning peaks in occurrence are now well-documented for acute myocardial infarction, sudden cardiac death, transient m...

    journal_title：American heart journal

    pub_type： 杂志文章,评审

    doi：10.1016/s0002-8703(99)70390-x

    authors： Muller JE

    更新日期：1999-04-01 00:00:00

  • Chronic obstructive pulmonary disease in heart failure. Prevalence, therapeutic and prognostic implications.

    abstract：BACKGROUND:Patients with heart failure (HF) frequently have comorbidities. Frequency, prognostic, and therapeutic implications of chronic obstructive pulmonary disease (COPD) in HF are largely unknown. We aimed to assess the prevalence and prognostic implications of COPD in a sample of stable patients with HF and to de...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2007.10.040

    authors： Mascarenhas J,Lourenço P,Lopes R,Azevedo A,Bettencourt P

    更新日期：2008-03-01 00:00:00

  • Primary prevention in patients with hypertension: comments on the clinical implications of the MAPHY Study. Metoprolol Atherosclerosis Prevention in Hypertensives Study.

    abstract：:The MAPHY Study was conducted to investigate whether metoprolol, a relatively beta 1-selective beta-blocker, given as initial antihypertensive treatment, would lower cardiovascular complications of high blood pressure to a greater extent than do thiazide diuretics as initial treatment at similar blood pressure control...

    journal_title：American heart journal

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/0002-8703(88)90112-3

    authors： Wikstrand J

    更新日期：1988-07-01 00:00:00

  • Risk stratification in survivors of acute myocardial infarction: routine cardiac catheterization and angiography is a reasonable approach in most patients.

    abstract：:Noninvasive risk assessment in survivors of AMI can effectively subdivide patients into groups with differing risk profiles after hospital discharge, but some patients at risk for late death or recurrent AMI may be incorrectly identified; data from cardiac catheterization and angiography provide complementary and gene...

    journal_title：American heart journal

    pub_type： 社论

    doi：10.1016/0002-8703(91)90747-6

    authors： Kulick DL,Rahimtoola SH

    更新日期：1991-02-01 00:00:00

  • Atrial septal defect resulting from mitral balloon valvuloplasty: relation of defect morphology to transseptal balloon catheter delivery.

    abstract：:Percutaneous balloon mitral valvuloplasty has been shown to be an effective means of reducing mitral valve gradient and increasing mitral valve area in patients with mitral stenosis. Most techniques currently employed for performing this procedure involve delivery of one or two balloon valvuloplasty catheters through ...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/s0002-8703(05)80279-0

    authors： Fields CD,Slovenkai GA,Isner JM

    更新日期：1990-03-01 00:00:00

  • The effects of cytochrome C on the extent of myocardial infarction and regional function of the ischemic myocardium.

    abstract：:The effects of cytochrome C, an electron carrier in the process of oxidative phosphorylation, on infarct size and regional left ventricular function after a coronary artery occlusion were investigated. Thus, in 30 dogs, 1 minute after left anterior descending coronary artery occlusion, 99mTc-labeled albumin microspher...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(87)90019-6

    authors： Zalewski A,Goldberg S,Krol R,Maroko PR

    更新日期：1987-01-01 00:00:00

  • Isovolumic relaxation time varies predictably with its time constant and aortic and left atrial pressures: implications for the noninvasive evaluation of ventricular relaxation.

    abstract：:The isovolumic relaxation time (IVRT) is an important noninvasive index of left ventricular diastolic function. Despite its widespread use, however, the IVRT has not been related analytically to invasive parameters of ventricular function. Establishing such a relationship would make the IVRT more useful by itself and ...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(92)90416-s

    authors： Thomas JD,Flachskampf FA,Chen C,Guererro JL,Picard MH,Levine RA,Weyman AE

    更新日期：1992-11-01 00:00:00

  • Significance of hypotension preceding fatal ventricular tachyarrhythmias in post-coronary obstruction sudden death.

    abstract：:While sudden death after acute myocardial infarction or ischemia most commonly occurs in the first few minutes, usually from tachyarrhythmias, little is known of associated hemodynamics. We monitored hemodynamics for 15 minutes following coronary embolization with mercury in 31 awake dogs. In 17 nonsurvivors, mean art...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(81)90131-9

    authors： Franciosa JA,Heckel R

    更新日期：1981-04-01 00:00:00

  • Evaluation of systolic time intervals in patients with angina pectoris.

    abstract：:We have explored the systolic time intervals of 52 patients with angina pectoris at the time of their hospitalization in our wards. Our results are in close agreement with published data, essentially indicating prolongation of the preejection time and shortening of the ejection time. These alterations of systolic time...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(83)90237-5

    authors： Randazzo A,Sardella F,Martinotti R,Daffara G,Parziale M,Cremonesi G

    更新日期：1983-05-01 00:00:00

  • Mode of deployment of coronary Palmaz-Schatz stents after implantation with the stent delivery system: an intravascular ultrasound study.

    abstract：:The stent delivery system (SDS) is a sheath-covered Palmaz-Schatz stent mounted on a 3.0, 3.5, or 4.0 mm compliant polyethylene balloon catheter; the balloon resists maximal inflation pressures of 5.7, 6.2, or 6.0 atm, respectively. It is postulated that these pressures are too low to obtain optimal stent deployment. ...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(95)90308-9

    authors： Kiemeneij F,Laarman G,Slagboom T

    更新日期：1995-04-01 00:00:00

  • "Silent" myocardial ischemia during and after exercise testing in patients with coronary artery disease.

    abstract：:Although many patients with coronary artery disease (CAD) have a positive exercise test without pain, the frequency and significance of this "silent" ischemia is unclear. Therefore, we studied 122 consecutive clinically stable patients with angiographically defined CAD (greater than 75 per cent luminal stenosis) and a...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(78)90234-x

    authors： Lindsey HE Jr,Cohn PF

    更新日期：1978-04-01 00:00:00

  • New phenotype of familial dilated cardiomyopathy and conduction disorders.

    abstract：BACKGROUND:Familial dilated cardiomyopathy (FDCM) is attributed to defects in cytoskeletal proteins, and different patterns of inheritance and phenotypic expressions according to assorted-protein modifications have been identified to date. We describe a clinical family study with 24 individuals in 3 generations affecte...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1067/mhj.2003.141

    authors： Oropeza ES,Cadena CN

    更新日期：2003-02-01 00:00:00

  • Decreased peripheral blood flow in the pathogenesis of the metabolic syndrome comprising hypertension, hyperlipidemia, and hyperinsulinemia.

    abstract：:Major cardiovascular risk factors, such as hypertension, hyperlipidemia, and diabetes, often cluster in the same individuals. It has been claimed that obesity, hyperinsulinemia, insulin resistance, and a deranged intracellular handling of ions have pathogenetic importance in the development of this metabolic syndrome....

    journal_title：American heart journal

    pub_type： 杂志文章,评审

    doi：10.1016/0002-8703(93)90446-g

    authors： Lind L,Lithell H

    更新日期：1993-05-01 00:00:00

  • Predictors of prognosis in severe chronic heart failure.

    abstract：:A total of 127 patients with chronic heart failure referred to our exercise laboratory were studied retrospectively to identify parameters predictive of prognosis. Patients were followed for a mean of 14.6 months. The group as a whole had severe ventricular dysfunction with a median ejection fraction of 17% and a medi...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(92)90656-g

    authors： Parameshwar J,Keegan J,Sparrow J,Sutton GC,Poole-Wilson PA

    更新日期：1992-02-01 00:00:00

  • A demonstration of differential refractoriness within a single fascicle of the human ventricular specialized conduction system.

    abstract：:In 15 patients with left bundle branch block (LBBB), atrial (A), His bundle (H), and ventricular (V) electrograms were recorded. Successively more premature atrial depolarizations were introduced via a catheter in the right antrium. In eight patients, the ventricular specialized conducting system (VSCS) was the most r...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(75)90194-5

    authors： Cannom DS,Goldreyer BN,Damato AN

    更新日期：1975-06-01 00:00:00

  • Perioperative beta-blocker withdrawal and mortality in vascular surgical patients.

    abstract：OBJECTIVE:Our purpose was to determine the effect of postoperative beta-blocker withdrawal on mortality and cardiovascular events after vascular surgery. METHODS:Detailed data were collected on perioperative cardiovascular medication use and discontinuation and cardiovascular risk factors among consecutive major vascu...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1067/mhj.2001.111547

    authors： Shammash JB,Trost JC,Gold JM,Berlin JA,Golden MA,Kimmel SE

    更新日期：2001-01-01 00:00:00

  • The economic consequences of non-evidence-based clopidogrel use.

    abstract：BACKGROUND:Clinical trials have helped clarify the efficacy of clopidogrel for the treatment and prevention of vascular disease. Costs for its use exceeded $5.9 billion in 2005, making it the second greatest source of drug expenditure in the world. However, little is known about the appropriateness of that use. Overuse...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2007.11.039

    authors： Choudhry NK,Levin R,Avorn J

    更新日期：2008-05-01 00:00:00

  • Return to the workforce following infective endocarditis-A nationwide cohort study.

    abstract：BACKGROUND:The ability to return to work after infective endocarditis (IE) holds important socioeconomic consequences for both patients and society, yet data on this issue are sparse. We examined return to the workforce and associated factors in IE patients of working age. METHODS:Using Danish nationwide registries, w...

    journal_title：American heart journal

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.ahj.2017.09.009

    authors： Butt JH,Kragholm K,Dalager-Pedersen M,Rørth R,Kristensen SL,Chaudry MS,Valeur N,Østergaard L,Torp-Pedersen C,Gislason GH,Køber L,Fosbøl EL

    更新日期：2018-01-01 00:00:00

  • Validation of pressure-volume data obtained in patients by initial transit radionuclide angiocardiography.

    abstract：:In order to validate the measurement of pressure-volume loops and stroke work in humans, simultaneous digital subtraction ventriculography (DSA) and first-pass radionuclide angiocardiography (RNA) coupled with high-fidelity micromanometer left ventricular pressure measurements were undertaken in 34 patients, mean age ...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(89)90234-2

    authors： Harpole DH,Skelton TN,Davidson CJ,Jones RH,Bashore TM

    更新日期：1989-11-01 00:00:00

  • Transitional adherence and persistence in the use of aldosterone antagonist therapy in patients with heart failure.

    abstract：BACKGROUND:Aldosterone antagonist therapy is recommended for selected patients with heart failure and reduced ejection fraction. Adherence to therapy in the transition from hospital to home is not well understood. METHODS:We identified patients with heart failure and reduced ejection fraction who were ≥65 years old, e...

    journal_title：American heart journal

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.ahj.2013.03.007

    authors： Curtis LH,Mi X,Qualls LG,Check DK,Hammill BG,Hammill SC,Heidenreich PA,Masoudi FA,Setoguchi S,Hernandez AF,Fonarow GC

    更新日期：2013-06-01 00:00:00

  • Effects of hyperoxia on myocardial injury following cardioversion-A randomized clinical trial.

    abstract：:Oxygen has long been assumed beneficial for all ill and injured patients. However, hyperoxia may be harmful and aggravate myocardial injury such as that caused by myocardial infarction. We aimed to investigate if hyperoxia increases myocardial injury following direct current cardioversion compared with room air. METH...

    journal_title：American heart journal

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.ahj.2017.10.006

    authors： Lauridsen KG,Schmidt AS,Adelborg K,Bach L,Hornung N,Jepsen SM,Deakin CD,Rickers H,Løfgren B

    更新日期：2018-02-01 00:00:00

  • Incidence of atrial fibrillation in whites and African-Americans: the Atherosclerosis Risk in Communities (ARIC) study.

    abstract：OBJECTIVES:To define the incidence and cumulative risk of atrial fibrillation (AF) in a population-based cohort of whites and African Americans. BACKGROUND:African-Americans reportedly have a lower risk of AF than whites despite their higher exposure to AF risk factors. However, precise estimates of AF incidence in Af...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2009.05.010

    authors： Alonso A,Agarwal SK,Soliman EZ,Ambrose M,Chamberlain AM,Prineas RJ,Folsom AR

    更新日期：2009-07-01 00:00:00

  • Adverse association between diabetic retinopathy and cardiac structure and function.

    abstract：BACKGROUND:Recent work has demonstrated a link between retinopathy, a marker of microvascular disease, and the development of heart failure, a finding particularly relevant in individuals with diabetes. Our objective was to assess the relationship between retinopathy and cardiac structure and function in a cohort of in...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2008.10.019

    authors： Aguilar D,Hallman DM,Piller LB,Klein BE,Klein R,Devereux RB,Arnett DK,Gonzalez VH,Hanis CL

    更新日期：2009-03-01 00:00:00

  • Patterns of inflammation associated with peripheral arterial disease: the InCHIANTI study.

    abstract：OBJECTIVE:To determine whether peripheral arterial disease is associated with high circulating levels of pro-inflammatory cytokines, independent of confounders. METHODS:Participants were 955 men and women aged 60 years and older representative of the population in 2 Italian communities (107 with peripheral arterial di...

    journal_title：American heart journal

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.ahj.2004.09.032

    authors： McDermott MM,Guralnik JM,Corsi A,Albay M,Macchi C,Bandinelli S,Ferrucci L

    更新日期：2005-08-01 00:00:00

  • Combined use of high-sensitivity cardiac troponin T and N-terminal pro-B type natriuretic peptide improves measurements of performance over established mortality risk factors in chronic heart failure.

    abstract：BACKGROUND:Heart failure still maintains a high mortality. Biomarkers reflecting different pathophysiological pathways are under evaluation to better stratify the mortality risk. The objective was to assess high-sensitivity cardiac troponin T (hs-cTnT) in combination with N-terminal pro-B type natriuretic peptide (NT-p...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2012.03.004

    authors： de Antonio M,Lupon J,Galan A,Vila J,Urrutia A,Bayes-Genis A

    更新日期：2012-05-01 00:00:00

  • Clinical status of patients removed from a transplant waiting list rivals that of transplant recipients at significant cost savings.

    abstract：:We retrospectively contrasted the medical outcome of patients removed from the heart transplant consideration list because of clinical improvement with that of transplant recipients. Of 60 patients awaiting transplantation, 18 were removed from the list (group A), and 42 required transplant or died (group B). Group A ...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/s0002-8703(96)90462-7

    authors： Levine TB,Levine AB,Goldberg AD,Tobes M,Narins B,Lesch M

    更新日期：1996-12-01 00:00:00

  • Acute and chronic effects of ketanserin on the electrophysiologic properties of isolated rabbit ventricular myocardium: particular reference to repolarization.

    abstract：:The acute and chronic cellular electrophysiologic actions of ketanserin, a selective blocker of 5-hydroxytriptamine (5-HT2) receptor, were examined in the isolated rabbit ventricular muscle. This work was prompted by the recent observations that small numbers of patients treated with hypertension develop QTc prolongat...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(88)90012-9

    authors： Kamiya K,Venkatesh N,Singh BN

    更新日期：1988-06-01 00:00:00

  • Probable postcardiotomy syndrome following implantation of a transvenous pacemaker: report of the first case.

    abstract：:The syndrome of fever and pericarditis is reported following implantation of a transvenous pacemaker in a 72-year-old man. The pacemaker was placed for prophylactic reasons (i.e., presence of bifascicular block). The syndrome resolved spontaneously after over four weeks of fever and a pericardial friction rub. Perfora...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(75)90227-6

    authors： Kaye D,Frankl W,Arditi LI

    更新日期：1975-11-01 00:00:00