Measuring costs and financial benefits in randomized controlled trials.

Abstract:

:Economic assessment can be incorporated into clinical trials to evaluate and compare the costs and benefits of different health care programs. In this article the three main types of evaluation are discussed: cost-effectiveness analysis, cost-utility analysis, and cost-benefit analysis. The measurement of direct and indirect costs is described and specific examples are quoted. Full economic analyses are given for the use of naftidrofuryl in the treatment of acute cerebral hemisphere infarction and the use of auranofin in the treatment of rheumatoid arthritis. Economic evaluation is seen to be justified whenever a more expensive treatment is expected to produce greater benefit. Such analyses should consider quality of life and health status, as well as the more easily identifiable outcomes.

journal_name

Am Heart J

journal_title

American heart journal

authors

Bulpitt CJ,Fletcher AE

doi

10.1016/s0002-8703(05)80059-6

subject

Has Abstract

pub_date

1990-03-01 00:00:00

pages

766-70; discussion 770-1

issue

3 Pt 2

eissn

0002-8703

issn

1097-6744

pii

S0002-8703(05)80059-6

journal_volume

119

pub_type

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