Clofibrate effects: mitochondria vs exercise tolerance in aging hamsters.

abstract：:A pilot study was performed to determine the safety and efficacy of coronary pulsed mid-infra-red laser angioplasty. The laser was coupled with a novel 2.0 mm multifiber catheter consisting of 37 optical fibers of 150 microns each arranged concentrically around a 0.018-inch central lumen and a soft leading tapered dis...

journal_title：American heart journal

authors： Geschwind HJ,Dubois-Rande JL,Zelinsky R,Morelle JF,Boussignac G

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:Systemic markers of inflammation increase after percutaneous coronary intervention (PCI). The rise in inflammatory markers after PCI is frequently attributed to the inflammatory stimulus associated with coronary artery injury during balloon inflation and coronary stent implantation. The aim of this study was...

journal_title：American heart journal

authors： Goldberg A,Zinder O,Zdorovyak A,Diamond E,Lischinsky S,Gruberg L,Markiewicz W,Beyar R,Aronson D

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Many chronic heart failure (CHF) patients have low vitamin D (VitD) and high plasma renin activity (PRA), which are both associated with poor prognosis. Vitamin D may inhibit renin transcription and lower PRA. We investigated whether vitamin D3 (VitD3) supplementation lowers PRA in CHF patients. METHODS AND...

journal_title：American heart journal

authors： Schroten NF,Ruifrok WP,Kleijn L,Dokter MM,Silljé HH,Lambers Heerspink HJ,Bakker SJ,Kema IP,van Gilst WH,van Veldhuisen DJ,Hillege HL,de Boer RA

更新日期：2013-08-01 00:00:00

abstract：:Ambulatory ECG recordings were obtained from 313 consecutive, totally symptom-free male subjects on whom cardiac catheterization was subsequently performed for occupational reasons. These recordings were examined for ventricular ectopy and the results were studied in relation to the findings on selective coronary angi...

journal_title：American heart journal

authors： Batchelor AJ,Kruyer WB,Hickman JR Jr

更新日期：1989-06-01 00:00:00

abstract：:Magnetic resonance imaging (MRI) produces high-resolution images of great-vessel anatomy in pediatric patients. In this study seven patients, aged 6 to 27 months were evaluated by using gated MRI and two-dimensional echocardiography 4 to 26 months after arterial switch operation for D-transposition of the great arteri...

journal_title：American heart journal

authors： Hardy CE,Helton GJ,Kondo C,Higgins SS,Young NJ,Higgins CB

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:Standard gray-scale imaging (GSI), three-dimensional (3D) echocardiography has been shown to be superior to two-dimensional echocardiography in measuring left ventricular volume. However, the often relatively poor quality of transthoracic gray-scale data can limit the potential application of this technique....

journal_title：American heart journal

authors： Lange A,Palka P,Nowicki A,Olszewski R,Anderson T,Adamus J,Sutherland GR,Fox KA

更新日期：1998-06-01 00:00:00

abstract：:The amount of cross-sectional area narrowing by atherosclerotic plaques in each 5 mm long sement of the left main, left anterior descending, left circumflex, and right coronary arteries was analyzed at necropsy in 15 patients with type II hyperlipoproteinemia (HLP), in 13 with type IV HLP, and in 10 with known normal ...

journal_title：American heart journal

authors： Cabin HS,Roberts WC

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:There is increasing evidence that transplantation of autologous stem cells improves cardiac function after acute myocardial infarction (AMI). For propagation of peripheral blood stem cells (PBSCs), application of granulocyte-colony stimulating factor (G-CSF) has been shown to be feasible, effective, and safe...

journal_title：American heart journal

authors： Steinwender C,Hofmann R,Kammler J,Kypta A,Pichler R,Maschek W,Schuster G,Gabriel C,Leisch F

更新日期：2006-06-01 00:00:00

abstract：:Release of thromboxane (TXA2) during acute myocardial infarction may be an important contributing factor in the genesis of ventricular fibrillation (VF). We assessed the effect of selective TXA2 inhibition on vulnerability to VF after total occlusion of the anterior descending coronary artery in chloralose-anesthetize...

journal_title：American heart journal

authors： O'Connor KM,Friehling TD,Kelliher GJ,MacNab MW,Wetstein L,Kowey PR

更新日期：1986-04-01 00:00:00

abstract：:Flow beyond a stenotic aortic valve (AS) is dynamically complex. Numerous hydraulic studies have demonstrated that at least four well-known major flow areas occur distal to a stenotic valve. These include a jet, an area alongside the jet (the parajet), an area of flow disturbance, and an area in which disturbed flow a...

journal_title：American heart journal

authors： Goldberg SJ,Kececioglu-Draelos Z,Sahn DJ,Valdes-Cruz LM,Allen HD

更新日期：1982-05-01 00:00:00

abstract：BACKGROUND:Aggressive management to reduce pulmonary artery systolic pressure (PASP) and pulmonary capillary wedge pressure (PCWP) reduces hospitalization rates and is crucial for patients awaiting transplantation but may require periodic invasive monitoring with right heart catheterization. METHODS:The purpose of thi...

journal_title：American heart journal

authors： Sherman HL,Avelar E,Grossman PM,Sachdev V,Oral H,Nicklas JM,Armstrong WF

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:Decreased heart rate variability (HRV) is often assumed to be associated with mortality in all patients after myocardial infarction (MI), independent of clinical factors or time after MI. METHOD:HRV was determined from Holter tapes in the Cardiac Arrhythmia Suppression Trial (CAST). Patients were 71 +/- 120...

journal_title：American heart journal

authors： Stein PK,Domitrovich PP,Kleiger RE,CAST Investigators.

更新日期：2004-02-01 00:00:00

abstract：:Twenty-seven patients with asymptomatic, nonsustained ventricular tachycardia whose evaluation suggested they were at high risk for sustained ventricular arrhythmias were treated with implantable cardioverter defibrillators. The option of conventional therapy (including the option of no therapy) was presented to each ...

journal_title：American heart journal

authors： Levine JH,Waller T,Hoch D,Greenberg S,Goldberger J,Kadish A

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:The same electrocardiographic (ECG) criteria that have been used for detection of left ventricular hypertrophy (LVH) have recently been recognized as predictors of adverse clinical outcomes, but this predictive ability is inadequately explored and understood. METHODS:A total of 14,984 participants from the ...

journal_title：American heart journal

authors： Estes EH,Zhang ZM,Li Y,Tereschenko LG,Soliman EZ

更新日期：2015-07-01 00:00:00

abstract：:Adventitial heparin delivery has been shown to inhibit thrombosis and neointimal thickening in a rat carotid injury model. To determine whether sustained, local delivery of hirulog, a potent antithrombin agent, inhibits thrombus formation and neointimal thickening after arterial stenting, silicone polymers containing ...

journal_title：American heart journal

authors： Muller DW,Gordon D,Topol EJ,Levy RJ,Golomb G

更新日期：1996-02-01 00:00:00

abstract：:Vessel dilator consisting of amino acids (a.a.) 31-67 and atrial natriuretic factor (ANF) composed of a.a. 99-126 of the 126 a.a. ANF prohormone circulate in humans and have potent vasodilatory properties. To determine whether these atrial natriuretic peptides are directly related to blood pressure in healthy normoten...

journal_title：American heart journal

authors： Sothern RB,Vesely DL,Kanabrocki EL,Bremner FW,Third JL,Boles MA,Nemchausky BM,Olwin JH,Scheving LE

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:Comparing the dose-response of a new drug to that of a previously studied drug can aid in understanding their relative potencies. Two dose-finding studies addressed the effect of a new drug, rosuvastatin, on its ability to decrease low-density lipoprotein cholesterol (LDL-C) levels. One of these studies incl...

journal_title：American heart journal

authors： Berry DA,Berry SM,McKellar J,Pearson TA

更新日期：2003-06-01 00:00:00

abstract：:While the total ischemic burden on the left ventricle represents the combined effects of both symptomatic and asymptomatic myocardial ischemia, the total vascular burden has many components including an increased systemic peripheral vascular resistance, an increased pulmonary vascular resistance, and an increased coro...

journal_title：American heart journal

authors： Opie LH,Commerford PJ

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Heart rate recovery (HRR) is a marker of vagal tone that is associated with survival, but little is known about the effects of exercise training on HRR in patients with heart failure (HF). METHODS:Twenty-four patients with HF were randomized to a 2-month residential rehabilitation program or to usual care. ...

journal_title：American heart journal

authors： Myers J,Hadley D,Oswald U,Bruner K,Kottman W,Hsu L,Dubach P

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:Familial hypertrophic cardiomyopathy (HCM) is a clinically and genetically heterogeneous disease of the sarcomere. Molecular genetic studies have shown that familial HCM involves mutations in 8 different genes that encode proteins of the myofibrillar apparatus. METHODS:We thoroughly searched these genes to ...

journal_title：American heart journal

authors： Lee W,Hwang TH,Kimura A,Park SW,Satoh M,Nishi H,Harada H,Toyama J,Park JE

更新日期：2001-02-01 00:00:00

abstract：:Evaluation of mitral regurgitation is difficult whether invasive or noninvasive methods are used. The determination of the regurgitant volume itself cannot be done in clinical practice with reasonable accuracy. In six sheep with chronic mitral regurgitation, left ventricular and left atrial pressures were recorded wit...

journal_title：American heart journal

authors： Teien D,Jones M,Shiota T,Yamada I,Sahn DJ

更新日期：1995-02-01 00:00:00

abstract：BACKGROUND:As stenting practice has evolved to include greater numbers of stents and adjunctive balloon catheters per case, concern has focused on the increasing costs of equipment for the delivery of stents. METHODS AND RESULTS:To evaluate temporal changes in costs of intracoronary stenting, we examined total costs, ...

journal_title：American heart journal

authors： Vaitkus PT,Adele C,Wells SK,Zehnacker JP

更新日期：1998-07-01 00:00:00

abstract：:One hundred thirty-three patients with dilated heart failure, 80 with coronary artery disease, and 53 with idiopathic dilated cardiomyopathy were followed for a mean of 29 months. Patients with ischemic heart disease had a worse prognosis than those classified as having idiopathic cardiomyopathy. Features from history...

journal_title：American heart journal

authors： Kelly TL,Cremo R,Nielsen C,Shabetai R

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:Improvement in risk stratification of patients with non-ST-segment elevation acute coronary syndrome (ACS) is a gateway to a more judicious treatment. This study examines whether the routine determination of left ventricular ejection fraction (EF) adds significant prognostic information to currently recommen...

journal_title：American heart journal

authors： Bosch X,Théroux P

更新日期：2005-08-01 00:00:00

abstract：:A-II exerts its activity on various target tissues by binding to its receptors. The discovery of local RASs and A-II receptors within various tissues has generated interest in the clinical usefulness of RAS inhibition by directly blocking the action of A-II at the receptor level. Different A-II receptor subtypes have ...

journal_title：American heart journal

authors： Kang PM,Landau AJ,Eberhardt RT,Frishman WH

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:Noninvasive methods are needed for the identification of women at highest risk for coronary artery disease (CAD) who might benefit most from aggressive preventive therapy. Identification of brachial artery atherosclerosis, which correlates with coronary artery atherosclerosis, may be useful to estimate or st...

journal_title：American heart journal

authors： Holubkov R,Karas RH,Pepine CJ,Rickens CR,Reichek N,Rogers WJ,Sharaf BL,Sopko G,Merz CN,Kelsey SF,McGorray SP,Reis SE

更新日期：2002-05-01 00:00:00

abstract：:The relation of alcohol consumption to coronary heart disease (CHD) was examined in a cohort of 1910 employed men aged 38 to 55 years enrolled in the Albany Study, a prospective investigation of factors related to cardiovascular disease. Two follow-up periods were examined, one between 1953-54 and 1971-72, the other a...

journal_title：American heart journal

authors： Gordon T,Doyle JT

更新日期：1985-08-01 00:00:00

abstract：BACKGROUND:Preoperative evaluation with contrast-enhanced multidetector computed tomographic angiography (MDCTA) is considered an "appropriate" indication based on expert consensus. We aimed to evaluate how the presurgical evaluation with MDCTA impacts the outcomes after reoperative cardiac surgery (RCS). METHODS:We r...

journal_title：American heart journal

authors： Maluenda G,Goldstein MA,Lemesle G,Weissman G,Weigold G,Landsman MJ,Hill PC,Pita F,Corso PJ,Boyce SW,Pichard AD,Waksman R,Taylor AJ

更新日期：2010-02-01 00:00:00

abstract：:Coronary arterial stenosis of varying severity and length were created in open-chest dogs. The reactive hyperemic responses (RHR) to 15 second occlusions were used to produce flow increases and judge the physiological significance of the narrowings. RHR are sensitive indices of functional impairment when resting flow ...

journal_title：American heart journal

authors： Hillis WS,Friesinger GC

更新日期：1976-12-01 00:00:00

abstract：BACKGROUND:Limited information is available on the health behavior profile of patients with premature acute coronary syndrome (ACS). The purpose of this study is to desribe the health bahvior of young patients with ACS at the baseline and 1 year post-ACS and examine sex differences. METHODS:GENESIS-PRAXY is a prospect...

journal_title：American heart journal

authors： Leung Yinko SS,Maheswaran J,Pelletier R,Bacon SL,Daskalopoulou SS,Khan NA,Eisenberg MJ,Karp I,Lavoie KL,Behlouli H,Pilote L,GENESIS-PRAXY investigators.

更新日期：2015-08-01 00:00:00