Effects of losartan and captopril on left ventricular systolic and diastolic function after acute myocardial infarction: results of the Optimal Trial in Myocardial Infarction with Angiotensin II Antagonist Losartan (OPTIMAAL) echocardiographic substudy.

abstract：:Left circumflex coronary blood flow was increased significantly (20 per cent) during stimulation of somatic afferent fibers. The change in CBF was associated with significant increases in heart rate and arterial pressure and significant decrease in coronary vascular resistance. Controlling heart rate or preventing car...

journal_title：American heart journal

authors： Kline RL

更新日期：1979-07-01 00:00:00

abstract：:Mechanisms responsible for the well-documented "protection" against myocardial ischemia and infarction in young women and subsequent loss of protection after menopause remain speculative. One possibility is that gender-related variables (such as endogenous hormone levels or regular loss of stored iron) alter the susce...

journal_title：American heart journal

authors： Przyklenk K,Ovize M,Bauer B,Kloner RA

更新日期：1995-06-01 00:00:00

abstract：:Over the past 11 years, a considerable body of evidence has accumulated implicating defects in the mitochondrial energy-generating pathway, oxidative phosphorylation, in a wide variety of degenerative diseases including myopathy and cardiomyopathy. Most classes of pathogenic mitochondrial DNA mutations affect the hear...

journal_title：American heart journal

authors： Wallace DC

更新日期：2000-02-01 00:00:00

abstract：:This case report presents a young adult with asymmetric septal hypertrophy (ASH) and syncope. Infranodal complete heart block was demonstrated as his cause for syncope. Therapy consisted of implantation of a A-V sequential pacemaker. Cardiac output determinations and systolic time intervals demonstrated the beneficial...

journal_title：American heart journal

authors： Chmielewski CA,Riley RS,Mahendran A,Most AS

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND:The optimal antiplatelet regimen in elective patients undergoing complex percutaneous coronary interventions (PCIs) is uncertain. We aimed to assess the impact of glycoprotein IIb/IIIa (GpIIb/IIIa) inhibition with eptifibatide in clinically stable subjects with diffuse coronary lesions. METHODS:Patients wit...

journal_title：American heart journal

authors： Biondi-Zoccai G,Valgimigli M,Margheri M,Marzocchi A,Lettieri C,Stabile A,Petronio AS,Binetti G,Bolognese L,Bellone P,Sardella G,Contarini M,Sheiban I,Marra S,Piscione F,Romeo F,Colombo A,Sangiorgi G

更新日期：2012-05-01 00:00:00

abstract：:Quinidine serum levels and pharmacokinetic data were assessed during steady state therapy with oral quinidine sulfate in 19 hospitalized patients who were being treated for ventricular arrhythmias. A new high performance liquid chromatography assay was employed. Four patients were studied both after the first dose of ...

journal_title：American heart journal

authors： Carliner NH,Crouthamel WG,Fisher ML,Mugmon MA,Vassar DL,Narang PK,Plotnick GD

更新日期：1979-12-01 00:00:00

abstract：BACKGROUND:The conventional use of 16-slice multidetector computed tomography (MDCT) remains somewhat limited for evaluating stenoses in vein graft distal anastomotic sites and in coronary arteries. We investigated the diagnostic accuracy of 64-slice MDCT for assessment of both grafts and coronary arteries in patients ...

journal_title：American heart journal

authors： Onuma Y,Tanabe K,Chihara R,Yamamoto H,Miura Y,Kigawa I,Fukuda S,Miyairi T,Nakajima H,Hara K

更新日期：2007-09-01 00:00:00

abstract：:The purpose of this study was to determine whether myocardium salvaged by reperfusion following coronary occlusion could respond to inotropic stimulation by dopamine. Mongrel dogs underwent a 2-hour occlusion of the proximal left anterior descending coronary artery, followed by reperfusion for 5 or 28 hours. Dopamine ...

journal_title：American heart journal

authors： Ellis SG,Wynne J,Braunwald E,Henschke CI,Sandor T,Kloner RA

更新日期：1984-01-01 00:00:00

abstract：:Evaluation of pericardial effusion was attempted with computed tomography in 11 patients. The volume and distribution of pericardial fluid were assessed with satisfactory resolution and the nature of the fluid was estimated by the difference in x-ray transparency (CT numbers). The volume of pericardial fluid calculate...

journal_title：American heart journal

authors： Tomoda H,Hoshiai M,Furuya H,Oeda Y,Matsumoto S,Tanabe T,Tamachi H,Sasamoto H,Koide S,Kuribayashi S,Matsuyama S

更新日期：1980-06-01 00:00:00

abstract：BACKGROUND:Data on left atrial/left atrial appendage (LA/LAA) thrombus resolution after non-vitamin K antagonist (VKA) oral anticoagulant treatment are scarce. The primary objective of X-TRA was to explore the use of rivaroxaban for the resolution of LA/LAA thrombi in patients with nonvalvular atrial fibrillation (AF) ...

journal_title：American heart journal

authors： Lip GY,Hammerstingl C,Marin F,Cappato R,Meng IL,Kirsch B,van Eickels M,Cohen A,X-TRA study and CLOT-AF registry investigators.

更新日期：2016-08-01 00:00:00

abstract：:There has been skepticism since the early days of open heart surgery that good long-term or even short-term results were possible with repair of pure mitral insufficiency. The authors report 145 patients in whom a markedly insufficient mitral valve was repaired 6 months to 17 years previously and another 55 patients i...

journal_title：American heart journal

authors： Kay JH,Zubiate P,Mendez MA,Vanstrom N,Yokoyama T

更新日期：1978-08-01 00:00:00

abstract：BACKGROUND:In 10,001 patients with stable coronary artery disease (CAD) enrolled in the Treating to New Targets (TNT) trial, 80 mg/d of atorvastatin (high-dose regimen) reduced the composite primary end point of death from CAD, nonfatal myocardial infarction, resuscitation from cardiac arrest, or stroke by 22% relative...

journal_title：American heart journal

authors： Mark DB,Knight JD,Cowper PA,Davidson-Ray L,Anstrom KJ

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:A common regimen for patients requiring dual-antiplatelet therapy who are at risk for gastrointestinal complications is the synchronous administration of enteric-coated (EC) aspirin, a proton pump inhibitor, and clopidogrel, although proton pump inhibitors have the potential for pharmacodynamic interaction w...

journal_title：American heart journal

authors： Gurbel PA,Bliden KP,Fort JG,Jeong YH,Shuldiner A,Chai S,Gesheff T,Antonino M,Gesheff M,Zhang Y,Tantry US

更新日期：2013-02-01 00:00:00

abstract：:In 14 patients with severe congestive heart failure, the effects of captopril on the forearm circulation were evaluated with strain gauge plethysmography. Changes in plasma renin activity, angiotensin II, norepinephrine, epinephrine, bradykinin, prostaglandin E2, and 6-keto-prostaglandin F1 alpha concentrations were a...

journal_title：American heart journal

authors： Nishimura H,Kubo S,Ueyama M,Kubota J,Kawamura K

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:This study investigates whether pioglitazone reduces neointimal hyperplasia after coronary stenting in nondiabetic patients with metabolic syndrome (MS) using intravascular ultrasound (IVUS). Pioglitazone, a novel insulin-sensitizing thiazolidinedione, has been shown to reduce neointimal hyperplasia after co...

journal_title：American heart journal

authors： Katayama T,Ueba H,Tsuboi K,Kubo N,Yasu T,Kuroki M,Saito M,Momomura S,Kawakami M

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Although the use of clopidogrel in patients "unlikely" to require coronary artery bypass grafting (CABG) is recommended in current guidelines of acute coronary syndrome (ACS) management, an important minority of patients require CABG. We assessed the ability to predict need for CABG from demographics known a...

journal_title：American heart journal

authors： Chew DP,Mahaffey KW,White HD,Huang Z,Hoekstra JW,Ferguson JJ,Califf RM,Aylward PE

更新日期：2008-05-01 00:00:00

abstract：:To explore the contribution of reperfusion injury to final infarct size after a short duration of ischemia, closed-chest dogs underwent 40 minutes of proximal left anterior descending artery occlusion followed by 3 days of reperfusion. Animals randomly received intracoronary adenosine (n = 8) at 3.75 mg/min during the...

journal_title：American heart journal

authors： Velasco CE,Turner M,Cobb MA,Virmani R,Forman MB

更新日期：1991-12-01 00:00:00

abstract：BACKGROUND:Platelet inhibition is critical in reducing both short- and long-term atherothrombotic risks after acute myocardial infarction (MI), especially among patients managed with percutaneous coronary intervention (PCI). Currently available antiplatelet medications, including adenosine diphosphate (ADP) receptor in...

journal_title：American heart journal

authors： Chin CT,Wang TY,Anstrom KJ,Zhu B,Maa JF,Messenger JC,Ryan KA,Davidson-Ray L,Zettler M,Effron MB,Mark DB,Peterson ED

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:In patients with coronary heart disease (CHD), atrial fibrillation (AF) is associated with increased morbidity and mortality. We investigated the associations between clinical risk factors and biomarkers with incident AF in patients with CHD. METHODS AND RESULTS:Around 13,153 patients with optimally treated...

journal_title：American heart journal

authors： Tomasdottir M MD,Held C MD, PhD,Hadziosmanovic N,Westerbergh J,Lindbäck J,Aylward PE,Budaj A,Cannon CP,Engdahl J,Granger CB,Koenig W,Manolis AJ,Oldgren J,Stewart RAH,Svennberg E,Vinereanu D,White HD,Siegbahn A,Wallent

更新日期：2021-01-02 00:00:00

abstract：BACKGROUND:Chronic infection with Chlamydia pneumoniae (Cpn) has been associated with atherosclerotic cardiovascular disease in sero-epidemiological, pathological and animal-model studies. Inflammation and immune activation has been proposed as the pathophysiological link between chronic infection and atherosclerosis. ...

journal_title：American heart journal

authors： Smith DA,Zouridakis EG,Mariani M,Fredericks S,Cole D,Kaski JC

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:The 6-minute walk test is a submaximal exercise test that is widely used as an outcomes measure in clinical trials and cardiopulmonary rehabilitation. An initial learning effect with repeated administration is well documented, but it is unknown whether this learning effect persists with time. METHODS:This s...

journal_title：American heart journal

authors： Wu G,Sanderson B,Bittner V

更新日期：2003-07-01 00:00:00

abstract：:Combination therapy with mexiletine (MEX) and quinidine (Q) may be more efficacious than monotherapy with either drug in suppressing ventricular arrhythmias, but its effects on ventricular performance are not known. Thus, right ventricular ejection fraction (RVEF) and left ventricular ejection fraction (LVEF) and wall...

journal_title：American heart journal

authors： Sheldon RS,Duff HJ,Mitchell LB,Wyse DG,Manyari DE

更新日期：1988-05-01 00:00:00

abstract：:Congestive heart failure with dilated left ventricle developed in two patients with symptomatic hypertrophic obstructive cardiomyopathy. Both patients previously underwent cardiac surgery for relief of their outflow obstruction. Alterations in structure and function of the left ventricle during their episode of cardia...

journal_title：American heart journal

authors： ten Cate FJ,Roelandt J

更新日期：1979-06-01 00:00:00

abstract：:To estimate the incidence of residual atrial septal perforation (ASP) following percutaneous transvenous mitral commissurotomy (PTMC) with the Inoue balloon catheter and to examine the factors contributing to ASP, we studied 46 patients with mitral stenosis undergoing PTMC. Residual ASP was evaluated by Doppler color ...

journal_title：American heart journal

authors： Ishikura F,Nagata S,Yasuda S,Yamashita N,Miyatake K

更新日期：1990-10-01 00:00:00

abstract：BACKGROUND:The Fontan operation results in a circulation that is dependent on low pulmonary vascular resistance to maintain an adequate cardiac output. Medical therapies that lower pulmonary vascular resistance may augment cardiac output and improve long-term outcomes. OBJECTIVES:This phase I/II clinical trial conduct...

journal_title：American heart journal

authors： Goldberg DJ,Zak V,Goldstein BH,Chen S,Hamstra MS,Radojewski EA,Maunsell E,Mital S,Menon SC,Schumacher KR,Payne RM,Stylianou M,Kaltman JR,deVries TM,Yeager JL,Paridon SM,Pediatric Heart Network Investigators.

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:The activated coagulation time (ACT) is a rapid measurement of a patient's level of heparin anticoagulation during cardiac catheterization. Patients receiving warfarin therapy occasionally are seen at the catheterization laboratory for emergent procedures. The effects of warfarin on ACT activity have not bee...

journal_title：American heart journal

authors： Chang RJ,Doherty TM,Goldberg SL

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:There is increasing evidence that transplantation of autologous stem cells improves cardiac function after acute myocardial infarction (AMI). For propagation of peripheral blood stem cells (PBSCs), application of granulocyte-colony stimulating factor (G-CSF) has been shown to be feasible, effective, and safe...

journal_title：American heart journal

authors： Steinwender C,Hofmann R,Kammler J,Kypta A,Pichler R,Maschek W,Schuster G,Gabriel C,Leisch F

更新日期：2006-06-01 00:00:00

abstract：:Although cost estimates for acute myocardial infarction are necessary for decisions about allocating scarce resources, there is a relative paucity of studies that estimate these costs across the entire spectrum of hospitals in actual clinical practice. This study sought to determine the correlates of in-hospital costs...

journal_title：American heart journal

authors： Krumholz HM,Chen J,Murillo JE,Cohen DJ,Radford MJ

更新日期：1998-03-01 00:00:00

abstract：:Stress has been identified as contributing to the development of cardiovascular disease. The pathophysiologic link between stress and disease still remains unclear. Because experimental stress testing in the laboratory permits the examination of the underlying mechanism for stress-induced blood pressure, analyses of c...

journal_title：American heart journal

authors： Rüddel H,Langewitz W,Schächinger H,Schmieder R,Schulte W

更新日期：1988-08-01 00:00:00

abstract：:"Stunned" myocardium prevents the assessment of myocardial salvage after streptokinase. In order to unmask "stunning," we sought to evaluate left ventricular inotropic contractile reserve of patients after streptokinase. Radionuclide ventriculograms were obtained in 75 consecutive patients 2 weeks after myocardial inf...

journal_title：American heart journal

authors： Satler LF,Kent KM,Fox LM,Goldstein HA,Green CE,Rogers WJ,Pallas RS,Del Negro AA,Pearle DL,Rackley CE

更新日期：1986-05-01 00:00:00