Progression to left ventricular dilatation in patients with hypertrophic obstructive cardiomyopathy.

abstract：:Controlled-release drug delivery technology has had a significant effect on the pharmacotherapy of cardiovascular diseases. Oral and transcutaneous controlled-release systems allow relatively short-acting drugs to be administered once or twice daily with comparable therapeutic efficacy and fewer adverse reactions comp...

journal_title：American heart journal

authors： Katz B,Rosenberg A,Frishman WH

更新日期：1995-02-01 00:00:00

abstract：:Current evidence suggests that the pathogenesis of atrial fibrillation (AF) is multifactorial. The observation that AF, once present, alters the electrophysiologic properties of the atrial myocardium causing self-perpetuation of the arrhythmia raised the importance of electrical remodeling in its pathogenesis. Althoug...

journal_title：American heart journal

authors： Kourliouros A,Savelieva I,Kiotsekoglou A,Jahangiri M,Camm J

更新日期：2009-02-01 00:00:00

abstract：:Fingolimod, a sphingosine-1-phosphate receptor (S1PR) modulator, was the first oral disease-modifying therapy approved for relapsing forms of multiple sclerosis; it reduces autoreactive lymphocytes' egress from lymphoid tissues by down-regulating S1PRs. Sphingosine-1-phosphate signaling is implicated in a range of phy...

journal_title：American heart journal

authors： Camm J,Hla T,Bakshi R,Brinkmann V

更新日期：2014-11-01 00:00:00

abstract：:In over 30 years of surveillance of 2873 women, 574 developed initial clinical manifestations of CHD. A number of antecedent metabolic risk factors proved atherogenic, including blood lipids, glucose tolerance, uric acid, and menopause. Serum total cholesterol predicts as strongly in women as in men. The predictive po...

journal_title：American heart journal

authors： Kannel WB

更新日期：1987-08-01 00:00:00

abstract：:Angiographic evidence of coronary dissection after angioplasty is found in 25% to 30% of cases. Although patients are usually asymptomatic, in a small percentage angioplasty-induced coronary dissection results in luminal impairment and ischemic complications. The present study was undertaken to identify factors respon...

journal_title：American heart journal

authors： Sharma SK,Israel DH,Kamean JL,Bodian CA,Ambrose JA

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:The metabolic syndrome is a cluster of clinical characteristics thought to be associated with increased coronary risk. This analysis evaluates angiographic progression of coronary disease in women who are postmenopausal with and without the metabolic syndrome enrolled in the Women's Angiographic Vitamin & Es...

journal_title：American heart journal

authors： Hsia J,Bittner V,Tripputi M,Howard BV

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:The CAPTIM trial suggested a survival benefit of prehospital fibrinolysis (FL) compared to primary percutaneous coronary intervention (PCI) in patients with ST-elevation myocardial infarction (STEMI) with a presentation delay of <2 hours. We examined the relationship between reperfusion strategy and time fro...

journal_title：American heart journal

authors： Westerhout CM,Bonnefoy E,Welsh RC,Steg PG,Boutitie F,Armstrong PW

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Aggressive management to reduce pulmonary artery systolic pressure (PASP) and pulmonary capillary wedge pressure (PCWP) reduces hospitalization rates and is crucial for patients awaiting transplantation but may require periodic invasive monitoring with right heart catheterization. METHODS:The purpose of thi...

journal_title：American heart journal

authors： Sherman HL,Avelar E,Grossman PM,Sachdev V,Oral H,Nicklas JM,Armstrong WF

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:Anemia is now recognized as being a common finding in CHF and is associated with increased mortality and morbidity. However, it is uncertain whether the anemia is actually causing the worse prognosis or is merely a marker of more severe cardiac disease. Previous intervention studies with subcutaneous (s.c.) ...

journal_title：American heart journal

authors： Palazzuoli A,Silverberg D,Iovine F,Capobianco S,Giannotti G,Calabrò A,Campagna SM,Nuti R

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Patients undergoing percutaneous coronary intervention (PCI) for unstable coronary syndromes have substantial emotional and spiritual distress that may promote procedural complications. Noetic (nonpharmacologic) therapies may reduce anxiety, pain and distress, enhance the efficacy of pharmacologic agents, or...

journal_title：American heart journal

authors： Krucoff MW,Crater SW,Green CL,Maas AC,Seskevich JE,Lane JD,Loeffler KA,Morris K,Bashore TM,Koenig HG

更新日期：2001-11-01 00:00:00

abstract：:Adverse drug events affect millions of patients each year. An important drug-drug interaction between amiodarone and vitamin K antagonists is encountered frequently in daily clinical practice. Warfarin, a commonly used anticoagulant, is a mixture of 2 optically active isomers (R and S enantiomers). The S enantiomer is...

journal_title：American heart journal

authors： Shirolkar SC,Fiuzat M,Becker RC

更新日期：2010-10-01 00:00:00

abstract：:Because limited information is available on significant arrhythmias after myocardial infarction in pediatric patients, this study was performed to determine the incidence and impact of ventricular tachycardia or fibrillation on the postinfarction course in patients aged 1 day to 16 years. Review of 96 such children sh...

journal_title：American heart journal

authors： Johnsrude CL,Towbin JA,Cecchin F,Perry JC

更新日期：1995-06-01 00:00:00

abstract：BACKGROUND:Erectile dysfunction (ED) is a common disorder in middle-aged men and is significantly influenced by cardiovascular risk factors (CVRFs) and cardiovascular disease. The substudy of the ONTARGET/TRANSCEND trials evaluates the relationship of erectile function to baseline characteristics and current treatment ...

journal_title：American heart journal

authors： Böhm M,Baumhäkel M,Probstfield JL,Schmieder R,Yusuf S,Zhao F,Koon T,ONTARGET\/TRANSCEND ED-Investigators.

更新日期：2007-07-01 00:00:00

abstract：:Several autoimmune diseases have been associated with increased frequencies of specific histocompatibility (HLA) antigens, particularly for the D (DR) locus, that may be linked to immune response genes. Rheumatic valvular heart disease (RHD) has been postulated to have autoimmune features, but HLA associations have no...

journal_title：American heart journal

authors： Anastasiou-Nana MI,Anderson JL,Carlquist JF,Nanas JN

更新日期：1986-11-01 00:00:00

abstract：:Probucol, a new cholesterol-lowering agent, was administered to ambulatory outpatients representing several classes of hyperlipoproteinemia (HL) for two years without dietary restriction. In 32 patients with Type II HL and 12 with Type IIB HL, statistically significant reduction in mean serum cholesterol levels occurr...

journal_title：American heart journal

authors： Parsons WB Jr

更新日期：1978-08-01 00:00:00

abstract：:The acute electrophysiologic effects of a bolus injection of 100 mg. of lidocaine were investigated in 39 patients with impulse formation and conduction defects by means of His-bundle recording and were correlated with plasma lidocaine levels. The effects of therapeutic plasma levels on conduction intervals and refrac...

journal_title：American heart journal

authors： Roos JC,Dunning AJ

更新日期：1975-06-01 00:00:00

abstract：:To evaluate the potential for hyperbaric oxygen (HBO) to produce transient improvement in function in areas of myocardium ischemic at rest (hibernating myocardium), 24 patients were studied within 1 week of acute myocardial infarction. Results were compared with single-photon emission computed tomography (SPECT) thall...

journal_title：American heart journal

authors： Swift PC,Turner JH,Oxer HF,O'Shea JP,Lane GK,Woollard KV

更新日期：1992-11-01 00:00:00

abstract：:Currently, automated systems for quantitative analysis by intracoronary ultrasound (ICUS) are restricted to the detection of the lumen. The aim of this study was to determine the accuracy and reproducibility of a new semiautomated contour detection method, providing off-line identification of the intimal leading edge ...

journal_title：American heart journal

authors： von Birgelen C,Di Mario C,Li W,Schuurbiers JC,Slager CJ,de Feyter PJ,Roelandt JR,Serruys PW

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:The TRANSFER-AMI study demonstrated that early routine percutaneous coronary intervention post-fibrinolysis (pharmacoinvasive strategy) is superior to conservative management for ST-elevation myocardial infarction. However, it is not clear whether treatment efficacy differs between men and women. METHODS:In...

journal_title：American heart journal

authors： Bhan V,Cantor WJ,Yan RT,Mehta SR,Morrison LJ,Heffernan M,Fitchett D,Džavík V,Ducas J,Borgundvaag B,Cohen EA,Goodman SG,Yan AT

更新日期：2012-09-01 00:00:00

abstract：:Although successful dilatation of a target lesion by means of percutaneous transluminal coronary angioplasty (PTCA) can be attained as frequently in elderly as in younger patients, elderly patients have a higher risk of complications. Furthermore, cohorts of patients older than 75 years and undergoing PTCA include mor...

journal_title：American heart journal

authors： Lindsay J Jr,Reddy VM,Pinnow EE,Little T,Pichard AD

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:The effect of raloxifene on aortic elasticity in healthy postmenopausal women is unknown. The purpose of the present study was to examine the effect of raloxifene on aortic elasticity and cardiovascular structure and function in healthy postmenopausal women. METHODS:A randomized, crossover, double-blind, pl...

journal_title：American heart journal

authors： Tritos NA,Goepfert L,Kissinger KV,Katsimaglis G,Manning WJ,Danias PG

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Heart rate recovery (HRR) is a marker of vagal tone that is associated with survival, but little is known about the effects of exercise training on HRR in patients with heart failure (HF). METHODS:Twenty-four patients with HF were randomized to a 2-month residential rehabilitation program or to usual care. ...

journal_title：American heart journal

authors： Myers J,Hadley D,Oswald U,Bruner K,Kottman W,Hsu L,Dubach P

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:Ideal cardiovascular health (ICH) aims at primordial prevention of cardiovascular diseases in the population. However, there is a lack of research describing ICH in youth from middle-income countries. The aims of this study were to describe the prevalence of ICH at 18 and 22-years old and to investigate the ...

journal_title：American heart journal

authors： Oliveira RS,Schneider BC,Callo-Quinte G,Oliveira IO,Gonçalves H,Wehrmeister F,Menezes AMB

更新日期：2021-01-25 00:00:00

abstract：BACKGROUND:Despite the common practice of clopidogrel loading for coronary stenting, the time dependence and degree of platelet inhibition after this therapy are not well defined. We sought to establish an optimal clopidogrel dosing regimen for sustained platelet inhibition in stented patients. METHODS AND RESULTS:Pla...

journal_title：American heart journal

authors： Gurbel PA,Cummings CC,Bell CR,Alford AB,Meister AF,Serebruany VL,Plavix Reduction Of New Thrombus Occurrence (PRONTO) trial.

更新日期：2003-02-01 00:00:00

abstract：:A 47-year-old man presented with exertional angina. Selective coronary arteriography showed complete systolic segmental occlusion of the left anterior descending coronary artery producing milking effect. Permanent relief of symptoms was achieved by surgical excision of myocardial bridges. Postoperative angiography per...

journal_title：American heart journal

authors： Betriu A,Tubau J,Sanz G,Magriña J,Navarro-Lopez F

更新日期：1980-08-01 00:00:00

abstract：BACKGROUND:Limited information is available on the health behavior profile of patients with premature acute coronary syndrome (ACS). The purpose of this study is to desribe the health bahvior of young patients with ACS at the baseline and 1 year post-ACS and examine sex differences. METHODS:GENESIS-PRAXY is a prospect...

journal_title：American heart journal

authors： Leung Yinko SS,Maheswaran J,Pelletier R,Bacon SL,Daskalopoulou SS,Khan NA,Eisenberg MJ,Karp I,Lavoie KL,Behlouli H,Pilote L,GENESIS-PRAXY investigators.

更新日期：2015-08-01 00:00:00

abstract：:Out of 156 patients with stable coronary heart disease randomized to either an exercise intervention group or a control group, 41 had complete gas analysis data. Continuous gas exchange data, including the ventilatory threshold, and selected heart rates were determined initially and at 1 year. The mean attendance for ...

journal_title：American heart journal

authors： Sullivan M,Ahnve S,Froelicher VF,Meyers J

更新日期：1985-03-01 00:00:00

abstract：PURPOSE:Viable myocardium after acute myocardial infarction may be characterized by magnetic resonance imaging (MRI) either by demonstration of recovery of wall motion under dobutamine stress or by perfusion patterns after contrast medium administration. This study examines the relation between the two techniques. MAT...

journal_title：American heart journal

authors： Dendale P,Franken PR,Block P,Pratikakis Y,De Roos A

更新日期：1998-05-01 00:00:00

abstract：:The electrocardiographic QT interval, with a wide variety of practical and theoretic applications in medicine, pharmacology, and cardiology, is critically dependent on heart rate as expressed by cycle length (RR). To account for this and permit intraindividual and interindividual comparisons of changing QT intervals, ...

journal_title：American heart journal

authors： Spodick DH,Rifkin RD,Rajasingh MC

更新日期：1990-07-01 00:00:00

abstract：:To compare the effects of two thrombolytic agents, streptokinase and recombinant tissue-type plasminogen activator (rTPA) with early heparinization, on left ventricular function, coronary patency and reinfarction rates, bleeding complications, and short- and long-term mortality, we studied 122 patients with acute myoc...

journal_title：American heart journal

authors： Cherng WJ,Chiang CW,Kuo CT,Lee CP,Lee YS

更新日期：1992-04-01 00:00:00