Effect of oral combination therapy with mexiletine and quinidine on left and right ventricular function.

abstract：BACKGROUND:Heart failure (HF) is one of the leading causes of morbidity and mortality among Americans. Despite increased interest in end-of-life care, the implications of do-not-resuscitate (DNR) orders in acutely ill patients with HF remain unclear. The goals of this observational study were to describe the use of DNR...

journal_title：American heart journal

authors： Chen JL,Sosnov J,Lessard D,Goldberg RJ

更新日期：2008-07-01 00:00:00

abstract：:Sudden cardiac death syndrome remains a major health problem responsible for approximately 400,000 deaths annually in the US. Effective therapies exist but are costly and are associated with potential complications. Currently used strategies for selection of the best candidates for implantable cardioverter defibrillat...

journal_title：American heart journal

authors： Kusmirek SL,Gold MR

更新日期：2007-04-01 00:00:00

abstract：:An extremely athletic 56-year-old male physician was found to have profound sinus bradycardia. His only symptom was markedly increased alertness while actively exercising. During pacemaker insertion he had an episode of prolonged sinus arrest terminated by a precordial thump. This case suggests that exercise can alter...

journal_title：American heart journal

authors： Marmor BM,Black MM

更新日期：1980-07-01 00:00:00

abstract：BACKGROUND:Depressive symptoms in patients with heart failure (HF) are common and might be associated with inflammation. No studies have examined both the cross-sectional and prospective association between inflammation and depressive symptoms in patients with HF with adequate correction for disease severity. The aim o...

journal_title：American heart journal

authors： Johansson P,Lesman-Leegte I,Svensson E,Voors A,van Veldhuisen DJ,Jaarsma T

更新日期：2011-06-01 00:00:00

abstract：:To estimate the incidence of residual atrial septal perforation (ASP) following percutaneous transvenous mitral commissurotomy (PTMC) with the Inoue balloon catheter and to examine the factors contributing to ASP, we studied 46 patients with mitral stenosis undergoing PTMC. Residual ASP was evaluated by Doppler color ...

journal_title：American heart journal

authors： Ishikura F,Nagata S,Yasuda S,Yamashita N,Miyatake K

更新日期：1990-10-01 00:00:00

abstract：:To test alterations in plasma potassium and magnesium levels with maximal exercise, 15 sedentary, healthy men (mean age 29 years) participated in a double-blind crossover study for 11 weeks with propranolol, atenolol, and placebo. Maximal exercise tests were done at baseline and after placebo and beta-blockade phases....

journal_title：American heart journal

authors： Fletcher GF,Sweeney ME,Fletcher BJ

更新日期：1991-01-01 00:00:00

abstract：:The clinical course and coronary arteriographic findings in eight patients with Prinzmetal's variant angina pectoris are reviewed and contrasted to previously reported cases. In six patients with S-T-elevation inferiorly, three had normal coronary arteriograms, one had complete right coronary artery occlusion, one ha...

journal_title：American heart journal

authors： Donsky MS,Harris MD,Curry GC,Blomqvist CG,Willerson JT,Mullins CB

更新日期：1975-05-01 00:00:00

abstract：:Ambulatory ECG recordings are routinely used to identify patients at increased risk of sudden cardiac death and to monitor changes in ventricular arrhythmias during antiarrhythmic drug therapy. The arrhythmia frequency established during the initial baseline has previously been reported to change during a second place...

journal_title：American heart journal

authors： Pratt CM,Francis M,Mahler S,Aogaichi K,Keus P,Young JB

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND:Myxomas, the most common cardiac tumor in adults, occur in the atria and are prone to embolization. Obstructive valvular tumors in infants occur in pulmonic and aortic valves and generally have a more benign course. METHODS:We conducted a review of our experience in infants with tumors obstructing the right...

journal_title：American heart journal

authors： Guntheroth WG,Fujioka MC,Reichenbach DD

更新日期：2002-05-01 00:00:00

abstract：:Serum digoxin and/quinidine concentration were measured before and following the institution of quinidine therapy in 11 patients who were receiving maintenance oral digoxin therapy and who required quinidine therapy for suppression of extrasystoles. Steady-state serum digoxin concentrations after quinidine administra...

journal_title：American heart journal

authors： Friedman HS,Chen TS

更新日期：1982-07-01 00:00:00

abstract：BACKGROUND:Galectin-3, a β-galactoside binding lectin involved in important regulatory roles in adhesion, inflammation, immunity, and fibrosis, may be relevant to atrial fibrillation (AF) etiology. METHODS:We included 8,436 participants free of AF at baseline (1996-1998) and with measures of plasma galectin-3 from the...

journal_title：American heart journal

authors： Fashanu OE,Norby FL,Aguilar D,Ballantyne CM,Hoogeveen RC,Chen LY,Soliman EZ,Alonso A,Folsom AR

更新日期：2017-10-01 00:00:00

abstract：AIM:The aim of the study was to assess and compare the safety of antiarrhythmic drugs (AADs) in an unselected real-world population of patients with atrial fibrillation (AF). METHODS AND RESULTS:This is a study of all patients with diagnosed AF in the Swedish Patient register who filled a prescription for sotalol, ami...

journal_title：American heart journal

authors： Friberg L

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Congestive heart failure (CHF) and heart transplantation (HTX) are characterized by endothelial dysfunction as indicated by elevation of markers of endothelial function, including endothelin and von Willebrand factor (vWF). However, previous studies included both patients with idiopathic dilated cardiomyopat...

journal_title：American heart journal

authors： Galatius S,Wroblewski H,Sørensen VB,Bie P,Parving HH,Kastrup J

更新日期：1999-03-01 00:00:00

abstract：:Mitochondria in skeletal and cardiac muscle have been found to be less stable in aging hamsters, in contrast to preparations from young animals. We have found previously that clofibrate (Atromid-S) will reverse this degeneration in the older hamsters. This study examined the exercise tolerance of aged hamsters, to see...

journal_title：American heart journal

authors： Guntheroth WG,Inamdar AR,Person R,Mackler B

更新日期：1977-10-01 00:00:00

abstract：:Estimating left ventricular wall stress has recognized applications, but formulae for global stress cannot be applied to ischemic ventricles. A mathematic method for estimating regional stress in infarcted ventricles has been described. The hypothesis tested was that exercise-induced ischemia increases end-systolic wa...

journal_title：American heart journal

authors： Ginzton LE,Rodrigues D,Shapiro SM,Laks MM,Conant R,Lobodzinski SM

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:In the United States as well as globally, Asians are a growing proportion of patients presenting with non-ST-segment elevation myocardial infarction (NSTEMI), yet little is known about their longitudinal outcomes. METHODS:We linked Centers for Medicare & Medicaid claims data to detailed clinical data for 37...

journal_title：American heart journal

authors： Xu W,Holmes DN,Becker RC,Roe MT,Peterson ED,Wang TY

更新日期：2013-12-01 00:00:00

abstract：:This study correlates the anatomic pathologic coronary anatomy found by arteriography in each of three groups of symptomatic patients, all with coronary artery disease, divided according to the magnitude of ST-segment depression after an adequate submaximal treadmill exercise test. Group I consists of 45 patients with...

journal_title：American heart journal

authors： Cheitlin MD,Davia JE,de Castro CM,Barrow EA,Anderson WT

更新日期：1975-03-01 00:00:00

abstract：BACKGROUND:The metabolic syndrome is a cluster of clinical characteristics thought to be associated with increased coronary risk. This analysis evaluates angiographic progression of coronary disease in women who are postmenopausal with and without the metabolic syndrome enrolled in the Women's Angiographic Vitamin & Es...

journal_title：American heart journal

authors： Hsia J,Bittner V,Tripputi M,Howard BV

更新日期：2003-09-01 00:00:00

abstract：:The conducting tissue of the heart was studied in 25 human cases of Chagas' myocarditis with a method which employs complete serial sections mounted on continuous transparent plastic tape. The pathological changes were correlated with electrocardiographic findings. The inflammation of the acute phase of Chagas' myocar...

journal_title：American heart journal

authors： Andrade ZA,Andrade SG,Oliveira GB,Alonso DR

更新日期：1978-03-01 00:00:00

abstract：BACKGROUND:The ACUTE Trial studied a transesophageal echocardiography (TEE)-guided strategy compared with a conventional strategy for management of patients with atrial fibrillation undergoing direct current cardioversion. The primary aim was to determine if patient functional capacity, measured by the Duke Activity St...

journal_title：American heart journal

authors： Jasper SE,Lieber EA,Murray RD,Apperson-Hansen C,Black IW,Grimm RA,Pape LA,Klein AL,ACUTE Investigators.

更新日期：2005-02-01 00:00:00

abstract：:In order to study the origin of the basal systolic murmurs in mitral stenosis, left and right heart catheterization was performed in 18 patients with mitral stenosis using intracardiac phonocardiography. Our data revealed that the basal systolic murmurs originated in the aorta, the pulmonary artery, and the outflow tr...

journal_title：American heart journal

authors： Kambe T,Suzuki S,Kato T,Hibi N,Fukui Y,Arakawa T,Nishimura K,Miwa A,Sakamoto N

更新日期：1978-10-01 00:00:00

abstract：BACKGROUND:Elevations of creatine kinase-MB (CK-MB) and cardiac troponin T (cTnT) have an uncertain long-term prognostic value after coronary artery bypass graft (CABG) surgery. We aimed to test the hypothesis that CK-MB and cTnT are predictors of long-term survival after CABG and to assess which of these 2 biomarkers ...

journal_title：American heart journal

authors： Søraas CL,Friis C,Engebretsen KV,Sandvik L,Kjeldsen SE,Tønnessen T

更新日期：2012-11-01 00:00:00

abstract：:To determine correlates of and recent trends in aspirin use in middle-age men and women, we analyzed data from population-based samples selected in four U.S. communities. Aspirin use (during a 2-week period preceding the study examination) was more prevalent in whites than in blacks (30% vs 11%; p < 0.001) and in men ...

journal_title：American heart journal

authors： Shahar E,Folsom AR,Romm FJ,Bisgard KM,Metcalf PA,Crum L,McGovern PG,Hutchinson RG,Heiss G

更新日期：1996-05-01 00:00:00

abstract：:We assessed the relationship between echocardiographic and hemodynamic parameters in 28 patients with documented acute myocardial infarction (AMI), who underwent M-mode echocardiography and Swan-Ganz catheterization during the same hospitalization. Patients with valvular heart disease were excluded from the study. On ...

journal_title：American heart journal

authors： Nador F,De Martini M,Binda A,Radrizzani D,Cirò E,Lotto A

更新日期：1984-07-01 00:00:00

abstract：BACKGROUND:Platelet inhibition is critical in reducing both short- and long-term atherothrombotic risks after acute myocardial infarction (MI), especially among patients managed with percutaneous coronary intervention (PCI). Currently available antiplatelet medications, including adenosine diphosphate (ADP) receptor in...

journal_title：American heart journal

authors： Chin CT,Wang TY,Anstrom KJ,Zhu B,Maa JF,Messenger JC,Ryan KA,Davidson-Ray L,Zettler M,Effron MB,Mark DB,Peterson ED

更新日期：2011-11-01 00:00:00

abstract：:We developed a new angiographic score of the extent of coronary disease (extent score), which we compared with conventional stenosis and vessel scores that emphasize the severity of stenosis. Scores were determined in 132 patients (29 women, 103 men with a mean age of 55 +/- 10 years) who underwent elective coronary a...

journal_title：American heart journal

authors： Sullivan DR,Marwick TH,Freedman SB

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:The human KCNE1 protein forms the β-subunit of the IKs potassium channel and is important in the regulation of the atrial action potential duration. The purpose of this study was to investigate the association between the nonsynonymous 112G>A mutation of the KCNE1 gene and postcardiac surgery atrial fibrilla...

journal_title：American heart journal

authors： Voudris KV,Apostolakis S,Karyofillis P,Doukas K,Zaravinos A,Androutsopoulos VP,Michalis A,Voudris V,Spandidos DA

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Carcinoid syndrome may involve right carcinoid heart disease (CHD), secondary to the release of vasoactive substances. Left CHD is rare, as the inactivation of serotonin by the lung protects the left heart. We attempted to evaluate the prevalence of CHD and patent foramen ovale (PFO) with seria...

journal_title：American heart journal

authors： Mansencal N,Mitry E,Forissier JF,Martin F,Redheuil A,Lepère C,Farcot JC,Joseph T,Lacombe P,Rougier P,Dubourg O

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:A large proportion of patients with heart failure (HF) have a large and poorly contracting left ventricle. The noninvasive recognition of the ischemic etiology of such patients is difficult, and for this purpose, usually patients undergo coronary angiography. It has been shown that cardiovascular magnetic re...

journal_title：American heart journal

authors： Casolo G,Minneci S,Manta R,Sulla A,Del Meglio J,Rega L,Gensini G

更新日期：2006-01-01 00:00:00

abstract：:The development of ECG Minnesota Q-QS codes and their subsequent evolution were studied in the first 692 subjects to enter the POSCH program who had had one MI. The mean interval from MI to entry into the study was 2.2 years. Sixty-three percent of the subjects developed the most significant code with the infarction. ...

journal_title：American heart journal

authors： Karnegis JN,Matts J,Tuna N

更新日期：1985-08-01 00:00:00