Abstract:
:X-ray solution scattering data from skeletal muscle troponin C and from calmodulin have been measured. Modeling studies based on the crystal structure coordinates for these proteins show discrepancies between the solution data and the crystal structure that indicate that if the size and shape of the globular domains are the same in solution as in the crystal, the distances between them must be smaller by several angstroms. Bringing the globular domains closer together requires structural changes in the interconnecting helix that joins them.
journal_name
Biochemistryjournal_title
Biochemistryauthors
Heidorn DB,Trewhella Jdoi
10.1021/bi00403a011subject
Has Abstractpub_date
1988-02-09 00:00:00pages
909-15issue
3eissn
0006-2960issn
1520-4995journal_volume
27pub_type
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