Biarsenical labeling of vesicular stomatitis virus encoding tetracysteine-tagged m protein allows dynamic imaging of m protein and virus uncoating in infected cells.

abstract：:Selecting human immunodeficiency virus (HIV) sequences for inclusion within vaccines has been a difficult problem, as circulating HIV strains evolve relentlessly and become increasingly divergent over time. We report an assessment of this divergence from three perspectives: (i) across different hosts as a function of ...

journal_title：Journal of virology

authors： Herbeck JT,Nickle DC,Learn GH,Gottlieb GS,Curlin ME,Heath L,Mullins JI

更新日期：2006-02-01 00:00:00

abstract：:Nonglucosylated T6 phage (T6gtam 16am30, hereafter called T6alpha gt-) were found to have two structural anomalies when compared with wild-type T6. The DNA of T6alpha gt- phage contains single-strand interruptions. These can be seen both during infection, in the pool of replicating DNA, and in DNA extracted from purif...

journal_title：Journal of virology

authors： Hewlett MJ,Mathews CK

更新日期：1975-04-01 00:00:00

abstract：:The relationship between the vaccinia virus hemagglutinin and hemadsorption was examined. Hemagglutinin synthesis was temporally related to the appearance of the hemadsorption reaction. Only chicken erythrocytes, which reacted with hemagglutinin, hemadsorbed to infected cells, and both of these reactions were inhibite...

journal_title：Journal of virology

authors： Blackman KE,Bubel HC

更新日期：1972-02-01 00:00:00

abstract：:We report on the use of spectral map analysis of the inter- and intraclade neutralization data of 14 sera of human immunodeficiency virus type 1 (HIV-1)-infected individuals and 16 primary isolates, representing genetic clades A to H in group M and group O. This multivariate analysis has been used previously to study ...

journal_title：Journal of virology

authors： Nyambi PN,Nkengasong J,Lewi P,Andries K,Janssens W,Fransen K,Heyndrickx L,Piot P,van der Groen G

更新日期：1996-09-01 00:00:00

abstract：:2G12 is a broadly neutralizing anti-HIV-1 monoclonal human IgG1 antibody reactive with a high-mannose glycan cluster on the surface of glycoprotein gp120. A key feature of this very highly mutated antibody is domain exchange of the heavy-chain variable region (V(H)) with the V(H) of the adjacent Fab of the same immuno...

journal_title：Journal of virology

authors： Huber M,Le KM,Doores KJ,Fulton Z,Stanfield RL,Wilson IA,Burton DR

更新日期：2010-10-01 00:00:00

abstract：:Understanding the mechanism(s) of action of the hepatitis B virus (HBV)-encoded protein HBx is fundamental to elucidating the underlying mechanisms of chronic liver disease and hepatocellular carcinoma caused by HBV infection. In our continued attempts to identify cellular targets of HBx, we have previously reported t...

journal_title：Journal of virology

authors： Rahmani Z,Huh KW,Lasher R,Siddiqui A

更新日期：2000-03-01 00:00:00

abstract：:Murine leukemia viruses isolated from radiation-induced BALB/c leukemias were characterized with respect to viral proteins and RNA. Analysis by sodium dodecyl sulfate-polyacrylamide gel electrophoresis of the viral structural proteins revealed that for p12, p15, p30, and gp70, three of four electrophoretic variants of...

journal_title：Journal of virology

authors： Ellis RW,Hopkins N,Fleissner E

更新日期：1980-02-01 00:00:00

abstract：:JC virus (JCV), along with other members of the polyomavirus family, encodes a class of highly conserved proteins, T antigens, that are capable of inducing aneuploidy in cultured cells. We have previously isolated T-antigen DNA variants of JCV from both colon cancer tissues and the corresponding nonneoplastic gastroin...

journal_title：Journal of virology

authors： Ricciardiello L,Chang DK,Laghi L,Goel A,Chang CL,Boland CR

更新日期：2001-02-01 00:00:00

abstract：:A substantial number of viruses have been demonstrated to subvert autophagy to promote their own replication. Recent publications have reported the proviral effect of autophagy induction on hepatitis B virus (HBV) replication. Hepatitis delta virus (HDV) is a defective virus and an occasional obligate satellite of HBV...

journal_title：Journal of virology

authors： Khabir M,Aliche AZ,Sureau C,Blanchet M,Labonté P

更新日期：2020-01-31 00:00:00

abstract：:A number of full-length cDNA clones of Kunjin virus (KUN) were previously prepared; it was shown that two of them, pAKUN and FLSDX, differed in specific infectivities of corresponding in vitro transcribed RNAs by approximately 100,000-fold (A. A. Khromykh et al., J. Virol. 72:7270-7279, 1998). In this study, we analyz...

journal_title：Journal of virology

authors： Liu WJ,Chen HB,Khromykh AA

更新日期：2003-07-01 00:00:00

abstract：UNLABELLED:A balance between the functions of the influenza virus surface proteins hemagglutinin (HA) and neuraminidase (NA) is thought to be important for the transmission of viruses between humans. Here we describe two pandemic H1N1 viruses, A/swine/Virginia/1814-1/2012 and A/swine/Virginia/1814-2/2012 (pH1N1low-1 an...

journal_title：Journal of virology

authors： Zanin M,Marathe B,Wong SS,Yoon SW,Collin E,Oshansky C,Jones J,Hause B,Webby R

更新日期：2015-06-01 00:00:00

abstract：:Mitochondria are important for the viral life cycle, mainly by providing the energy required for viral replication and assembly. A highly complex interaction with mitochondria is exerted by rubella virus (RV), which includes an increase in the mitochondrial membrane potential as a general marker for mitochondrial acti...

journal_title：Journal of virology

authors： Claus C,Schönefeld K,Hübner D,Chey S,Reibetanz U,Liebert UG

更新日期：2013-08-01 00:00:00

abstract：:Attempts to elicit broadly neutralizing antibody responses by human immunodeficiency virus type 1 (HIV-1) vaccine antigens have been met with limited success. To better understand the requirements for cross-neutralization of HIV-1, we have characterized the neutralizing antibody specificities present in the sera of th...

journal_title：Journal of virology

authors： Dhillon AK,Donners H,Pantophlet R,Johnson WE,Decker JM,Shaw GM,Lee FH,Richman DD,Doms RW,Vanham G,Burton DR

更新日期：2007-06-01 00:00:00

abstract：:The configuration of latent varicella-zoster virus (VZV) DNA was analyzed by PCR. Template DNA for both internal and terminal VZV primers was present in a 1:1 ratio in ganglionic DNA, compared with a 15:1 ratio in DNA extracted from VZV virions, indicating that the VZV genomic termini are adjacent in latently infected...

journal_title：Journal of virology

authors： Clarke P,Beer T,Cohrs R,Gilden DH

更新日期：1995-12-01 00:00:00

abstract：:The human immunodeficiency virus type 1 Vpu protein is a 16-kDa phosphoprotein which enhances the efficiency of virion production and induces rapid degradation of CD4, the cellular receptor for human immunodeficiency virus. The topology of membrane-inserted Vpu was investigated by using in vitro-synthesized Vpu cotran...

journal_title：Journal of virology

authors： Maldarelli F,Chen MY,Willey RL,Strebel K

更新日期：1993-08-01 00:00:00

abstract：:Glycoprotein B (gB) of herpes simplex virus (HSV) is one of four glycoproteins essential for viral entry and cell fusion. Recently, paired immunoglobulin-like type 2 receptor (PILRalpha) was identified as a receptor for HSV type 1 (HSV-1) gB. Both PILRalpha and a gD receptor were shown to participate in HSV-1 entry in...

journal_title：Journal of virology

authors： Fan Q,Lin E,Satoh T,Arase H,Spear PG

更新日期：2009-08-01 00:00:00

abstract：:Envelope glycoprotein E1 (gp51 to gp54) is the most antigenic protein of hog cholera virus or classical swine fever virus (CSFV). Four antigenic domains, A to D, have been mapped on E1 with a panel of monoclonal antibodies (MAbs) raised against CSFV strain Brescia. The boundaries of these domains have been established...

journal_title：Journal of virology

authors： van Rijn PA,Miedema GK,Wensvoort G,van Gennip HG,Moormann RJ

更新日期：1994-06-01 00:00:00

abstract：:A phylogenetic analysis of 52 published and 37 new nucleoprotein (NP) gene sequences addressed the evolution and origin of human and swine influenza A viruses. H1N1 human and classical swine viruses (i.e., those related to Swine/Iowa/15/30) share a single common ancestor, which was estimated to have occurred in 1912 t...

journal_title：Journal of virology

authors： Gorman OT,Bean WJ,Kawaoka Y,Donatelli I,Guo YJ,Webster RG

更新日期：1991-07-01 00:00:00

abstract：:The trans-activator Tat proteins coded by human immunodeficiency virus type 1 (HIV-1) and HIV-2 appear to be similar in structure and function. However, the Tat protein of HIV-2 (Tat2) activates the HIV-1 long terminal repeat (LTR) less efficiently than Tat1 (M. Emerman, M. Guyader, L. Montagnier, D. Baltimore, and M....

journal_title：Journal of virology

authors： Elangovan B,Subramanian T,Chinnadurai G

更新日期：1992-04-01 00:00:00

abstract：:Transfection has been found and characterized in pneumococcus. For replicating omega3 phage DNA extracted from infected cells, transfection was relatively efficient and rose linearly with DNA concentration and quadratically with time, according to T(T - 3.5) min(2). For mature DNA extracted from phage particles, trans...

journal_title：Journal of virology

authors： Porter RD,Guild WR

更新日期：1978-01-01 00:00:00

abstract：:The genome of all densoviruses (DNVs) so far isolated from mosquitoes or mosquito cell lines consists of a 4-kb single-stranded DNA molecule with a monosense organization (genus Brevidensovirus, subfamily Densovirinae). We previously reported the isolation of a Culex pipiens DNV (CpDNV) that differs significantly from...

journal_title：Journal of virology

authors： Baquerizo-Audiot E,Abd-Alla A,Jousset FX,Cousserans F,Tijssen P,Bergoin M

更新日期：2009-07-01 00:00:00

abstract：:We used deep sequencing of poly(A) RNA to characterize the transcriptome of an economically important eel virus, anguillid herpesvirus 1 (AngHV1), at a stage during the lytic life cycle when infectious virus was being produced. In contrast to the transcription of mammalian herpesviruses, the overall level of antisense...

journal_title：Journal of virology

authors： van Beurden SJ,Gatherer D,Kerr K,Galbraith J,Herzyk P,Peeters BP,Rottier PJ,Engelsma MY,Davison AJ

更新日期：2012-09-01 00:00:00

abstract：:Drug resistance remains a major concern for human immunodeficiency virus (HIV) treatment. To date, very few resistance mutations have emerged in first-line combination therapy that includes the integrase strand transfer inhibitor (INSTI) dolutegravir (DTG). In vitro, DTG selects for several primary mutations that indu...

journal_title：Journal of virology

authors： Van Rompay KKA,Hassounah S,Keele BF,Lifson JD,Ardeshir A,Watanabe J,Pham HT,Chertova E,Sowder R,Balzarini J,Mesplède T,Wainberg MA

更新日期：2019-01-04 00:00:00

abstract：:The accumulation of an abnormal, protease-resistant form of the protein PrP (PrP-res) in hosts with scrapie and related transmissible spongiform encephalopathies appears to be important in disease pathogenesis. To gain insight into the mechanism of PrP-res accumulation and the in vivo antiscrapie activity of certain p...

journal_title：Journal of virology

authors： Caughey B,Raymond GJ

更新日期：1993-02-01 00:00:00

abstract：:In order to clarify antigenic variations among various isolates of human herpesvirus 6 (HHV-6) and cross-reactivity among HHV-6, HHV-7, and human cytomegalovirus (HCMV) in the T-cell immune response, the antigenic specificity of the proliferative response mediated by 232 CD4+ human T-cell clones directed against HHV-6...

journal_title：Journal of virology

authors： Yasukawa M,Yakushijin Y,Furukawa M,Fujita S

更新日期：1993-10-01 00:00:00

abstract：UNLABELLED:Hepatitis C virus (HCV) is a major cause of chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma in humans. We showed previously that HCV induces autophagy for viral persistence by preventing the innate immune response. Knockdown of autophagy reduces extracellular HCV release, although the precis...

journal_title：Journal of virology

authors： Shrivastava S,Devhare P,Sujijantarat N,Steele R,Kwon YC,Ray R,Ray RB

更新日期：2015-11-18 00:00:00

abstract：UNLABELLED:Modified vaccinia virus Ankara (MVA) serves as a versatile platform in vaccine development. This highly attenuated orthopoxvirus, which cannot replicate in mammalian cells, triggers strong innate immune responses, including cell migration. Previously, we have shown that induction of chemokine (C-C motif) lig...

journal_title：Journal of virology

authors： Price PJ,Luckow B,Torres-Domínguez LE,Brandmüller C,Zorn J,Kirschning CJ,Sutter G,Lehmann MH

更新日期：2014-09-01 00:00:00

abstract：:The major adenovirus (Ad) capsid proteins hexon, penton, and fiber influence the efficiency and tropism of gene transduction by Ad vectors. Fiber is the high-affinity receptor binding protein that serves to mediate cell attachment in vitro when using coxsackie-adenovirus receptor (CAR)-containing cell lines. This cont...

journal_title：Journal of virology

authors： Schoggins JW,Nociari M,Philpott N,Falck-Pedersen E

更新日期：2005-09-01 00:00:00

abstract：:Escherichia coli K-12 wild type and a uvrA mutant derivative were used to construct isogenic strains bearing one, two, three, or more phage lambda cI genomes and containing increasing concentration of lambda repressor as measured by in vitro operator DNA-binding assays. The survival and phage induction in response to ...

journal_title：Journal of virology

authors： Baluch J,Sussman R

更新日期：1978-06-01 00:00:00

abstract：:We molecularly cloned the src coding region of tsNY68, a mutant of Rous sarcoma virus temperature sensitive (ts) for transformation, and constructed a series of ts wild-type recombinant src genes. DNA containing the hybrid genes was transfected into chicken cells together with viral vector DNA and helper viral DNA, an...

journal_title：Journal of virology

authors： Nishizawa M,Mayer BJ,Takeya T,Yamamoto T,Toyoshima K,Hanafusa H,Kawai S

更新日期：1985-12-01 00:00:00