Monocyte attachment to laminin in diabetes mellitus: The role of ATP.

abstract：:Podosomes are small, circular adhesions formed by cells such as osteoclasts, macrophages, dendritic cells, and endothelial cells. They comprise a protrusive actin core module and an adhesive ring module composed of integrins and cytoskeletal adaptor proteins such as vinculin and talin. Furthermore, podosomes are assoc...

journal_title：Cell adhesion & migration

authors： van den Dries K,Bolomini-Vittori M,Cambi A

更新日期：2014-01-01 00:00:00

abstract：:Cell migration requires a highly coordinated interplay between specialized plasma membrane adhesion complexes and the cytoskeleton. Protein phosphorylation/dephosphorylation modifications regulate many aspects of the integrin-cytoskeleton interdependence, including their coupling, dynamics, and organization to support...

journal_title：Cell adhesion & migration

authors： Arregui CO,González Á,Burdisso JE,González Wusener AE

更新日期：2013-09-01 00:00:00

abstract：:It is well recognized that a number of proteins present within adhesion complexes perform discrete signaling functions outside these adhesion complexes, including transcriptional control. In this respect, β-catenin is a well-known example of an adhesion protein present both in cadherin complexes and in the nucleus wh...

journal_title：Cell adhesion & migration

authors： van den Berg MC,Burgering BM

更新日期：2014-01-01 00:00:00

abstract：:Genetically engineered, conditionally replicating herpes simplex viruses type 1 (HSV-1) are promising therapeutic agents for brain tumors and other solid cancers. They can replicate in situ, spread and exhibit oncolytic activity via a direct cytocidal effect. One of the advantages of HSV-1 is the capacity to incorpora...

journal_title：Cell adhesion & migration

authors： Todo T

更新日期：2008-07-01 00:00:00

abstract：:There is currently great interest in the use of mesenchymal stem cells as a therapy for multiple sclerosis with potential to both ameliorate inflammatory processes as well as improve regeneration and repair. Although most clinical studies have used autologous bone marrow-derived mesenchymal stem cells, other sources s...

journal_title：Cell adhesion & migration

authors： Hou ZL,Liu Y,Mao XH,Wei CY,Meng MY,Liu YH,Zhuyun Yang Z,Zhu H,Short M,Bernard C,Xiao ZC

更新日期：2013-09-01 00:00:00

abstract：:Eph receptors and their membrane-bound ligands are intimately involved in the control of morphogenic processes during embryonic development and adult tissue homeostasis. By their ability to orchestrate cell migration, pattern formation and tissue integrity they are also prone to be involved in carcinogenic growth. In ...

journal_title：Cell adhesion & migration

authors： Kaenel P,Mosimann M,Andres AC

更新日期：2012-03-01 00:00:00

abstract：:Normal vascular development and angiogenesis is regulated by coordinated changes in cell-cell and cell-extracellular matrix (ECM) interactions. The Homeobox (Hox) family of transcription factors coordinately regulate expression of matrix degrading proteinases, integrins and ECM components and profoundly impact vascula...

journal_title：Cell adhesion & migration

authors： Arderiu G,Cuevas I,Chen A,Carrio M,East L,Boudreau NJ

更新日期：2007-10-01 00:00:00

abstract：:Since the time it was pioneered in 1992, intravital imaging of tumors at cellular resolution has offered us the extremely important opportunity of "seeing biology." However, until now, most studies were monitoring tumor cell behavior in the same animal over short times, requiring the combining of acquired data into a ...

journal_title：Cell adhesion & migration

authors： Gligorijevic B,Condeelis J

更新日期：2009-10-01 00:00:00

abstract：:The aim of this study was to compare uniaxial traction forces exerted by different cell types using a novel sensor design and to test the dependence of measured forces on cytoskeletal integrity. The sensor design detects forces generated between 2 contact points by cells spanning a gap. The magnitude of these forces v...

journal_title：Cell adhesion & migration

authors： Swierczewski R,Hedley J,Redfern CP

更新日期：2016-05-03 00:00:00

abstract：:The mechanical and structural properties of the extracellular matrix (ECM) play an important role in regulating cell fate. The natural ECM has a complex fibrillar structure and shows nonlinear mechanical properties, which are both difficult to mimic synthetically. Therefore, systematically testing the influence of ECM...

journal_title：Cell adhesion & migration

authors： Bruekers SM,Jaspers M,Hendriks JM,Kurniawan NA,Koenderink GH,Kouwer PH,Rowan AE,T S Huck W

更新日期：2016-09-02 00:00:00

abstract：:Anti-angiogenic vascular endothelial growth factor A (VEGF) 165b and pro-angiogenic VEGF 165 are generated from the same transcript, and their relative amounts are dependent on alternative splicing. The role of VEGF 165b has not been investigated in as much detail as VEGF 165, although it appears to be highly expresse...

journal_title：Cell adhesion & migration

authors： Peiris-Pagès M

更新日期：2012-11-01 00:00:00

abstract：:It has long been thought that the same molecules guide both trunk neural crest cells and motor axons as these cell types grow and extend to their target regions in developing embryos. There are common territories that are navigated by these cell types: both cells grow through the rostral portion of the somitic sclerot...

journal_title：Cell adhesion & migration

authors： Krull CE

更新日期：2010-10-01 00:00:00

abstract：:During brain development, billions of neurons organize into highly specific circuits. To form specific circuits, neurons must build the appropriate types of synapses with appropriate types of synaptic partners while avoiding incorrect partners in a dense cellular environment. Defining the cellular and molecular rules ...

journal_title：Cell adhesion & migration

authors： Basu R,Taylor MR,Williams ME

更新日期：2015-01-01 00:00:00

abstract：:Orderly cell migration is essential for embryonic development, efficient wound healing and a functioning immune system and the dysregulation of this process leads to a number of pathologies. The speed and direction of cell migration is critically dependent on the structural organization of focal adhesions in the cell....

journal_title：Cell adhesion & migration

authors： Bach CT,Schevzov G,Bryce NS,Gunning PW,O'Neill GM

更新日期：2010-04-01 00:00:00

abstract：:In this article, I discuss the hallmarks of hypoxia in vitro and in vivo and review work showing that many types of stem cell proliferate more robustly in lowered oxygen. I then discuss recent studies showing that alterations in the levels and the types of cell and substrate adhesion molecules are a notable response t...

journal_title：Cell adhesion & migration

authors： Crossin KL

更新日期：2012-01-01 00:00:00

abstract：:Angiogenesis, the growth of new blood vessels from pre-existing vessels, is a process involving endothelial cell proliferation, migration and vascular tube formation. One of the key molecules that regulate this process is the integrin beta3 subunit, a cell adhesion receptor that forms a heterodimer with the integrin a...

journal_title：Cell adhesion & migration

authors： Hayashi H,Kume T

更新日期：2009-01-01 00:00:00

abstract：:During development, dorsal root ganglion (DRG) neurons extend their axons toward the dorsolateral part of the spinal cord and enter the spinal cord through the dorsal root entry zone (DREZ). After entering the spinal cord, these axons project into the dorsal mantle layer after a 'waiting period' of a few days. We reve...

journal_title：Cell adhesion & migration

authors： Masuda T,Yaginuma H,Sakuma C,Ono K

更新日期：2009-04-01 00:00:00

abstract：:Trophoblast migration and invasion through the decidua and maternal uterine spiral arteries are crucial events in placentation. During this process, invasive trophoblast replace vascular endothelial cells as the uterine arteries are remodeled to form more permissive vessels that facilitate adequate blood flow to the g...

journal_title：Cell adhesion & migration

authors： Silva JF,Serakides R

更新日期：2016-03-03 00:00:00

abstract：:Directional cell migration is essential for almost all organisms during embryonic development, in adult life and contributes to pathological conditions. This is particularly critical during embryogenesis where it is essential that cells end up in their correct, precise locations in order to build a normal embryo. Many...

journal_title：Cell adhesion & migration

authors： Carmona-Fontaine C,Matthews H,Mayor R

更新日期：2008-10-01 00:00:00

abstract：:Changes in cell shape are associated with a variety of processes including cell migration, axon outgrowth, cell division and vesicle trafficking. C. elegans UNC-53 and its vertebrate homologs, the Navigators, are required for the migration of cells and the outgrowth of neuronal processes. The identification of novel m...

journal_title：Cell adhesion & migration

authors： Stringham EG,Schmidt KL

更新日期：2009-10-01 00:00:00

abstract：:Cell adhesion is a fundamental property of epithelial cells required for anchoring, migration and survival. During cell migration, the formation and disruption of adhesion sites is stringently regulated by integration of multiple, sequential signals acting in distinct regions of the cell. Recent findings implicate cyc...

journal_title：Cell adhesion & migration

authors： Tripathi BK,Zelenka PS

更新日期：2010-07-01 00:00:00

abstract：:The goal of this review is to highlight how emerging new models of filopodia assembly, which include tissue specific actin-bundling proteins, could provide more comprehensive representations of filopodia assembly that would describe more adequately and effectively the complexity and plasticity of epithelial cells.  Th...

journal_title：Cell adhesion & migration

authors： Khurana S,George SP

更新日期：2011-09-01 00:00:00

abstract：:Vinculin helps cells regulate and respond to mechanical forces. It is a scaffolding protein that tightly regulates its interactions with potential binding partners within adhesive structures-including focal adhesions that link the cell to the extracellular matrix and adherens junctions that link cells to each other-th...

journal_title：Cell adhesion & migration

authors： Dumbauld DW,García AJ

更新日期：2014-01-01 00:00:00

abstract：:The physical separation of the embryonic regions that give rise to the tissues and organs of multicellular organisms is a fundamental aspect of morphogenesis. Pioneer experiments by Holtfreter had shown that embryonic cells can sort based on "tissue affinities," which have long been considered to rely on differences i...

journal_title：Cell adhesion & migration

authors： Fagotto F,Winklbauer R,Rohani N

更新日期：2014-01-01 00:00:00

abstract：:Physical cues from the extracellular environment that influence cell shape and directional migration are transduced into changes in cytoskeletal organization and biochemistry through integrin-based cell adhesions to extracellular matrix (ECM). Paxillin is a focal adhesion (FA) scaffold protein that mediates integrin a...

journal_title：Cell adhesion & migration

authors： Sero JE,German AE,Mammoto A,Ingber DE

更新日期：2012-11-01 00:00:00

abstract：:Cellular motility is a fundamental process essential for embryonic development, wound healing, immune responses, and tissues development. Cells are mostly moving by crawling on external, or inside, substrates which can differ in their surface composition, geometry, and dimensionality. Cells can adopt different migrati...

journal_title：Cell adhesion & migration

authors： Siton-Mendelson O,Bernheim-Groswasser A

更新日期：2016-09-02 00:00:00

abstract：:Activation of platelet derived growth factor (PDGF) receptors causes context-dependent cellular responses, including proliferation and migration, and studies in model organisms have demonstrated that this receptor family (PDGFRα and PDGFRβ) is required in many mesenchymal and migratory cell populations during embryoni...

journal_title：Cell adhesion & migration

authors： Smith CL,Tallquist MD

更新日期：2010-10-01 00:00:00

abstract：:In addition to its well-defined role as an antagonist in apoptosis, we propose that BCL2 may act as an intracellular suppressor of cell motility and adhesion under certain conditions. Our evidence shows that, when over-expressed in both cancer and non-cancer cells, BCL2 can form a complex with actin and gelsolin that ...

journal_title：Cell adhesion & migration

authors： Ke H,Zhang JY,Akiyama SK,French JE

更新日期：2011-01-01 00:00:00

abstract：:An expanding body of evidence demonstrates that cells undergoing apoptosis send out a selection of molecular navigational signals including proteins, lipids and nucleotides that serve to recruit phagocytes to the dying targets which are subsequently engulfed and removed. This homeostatic process is essentially non-phl...

journal_title：Cell adhesion & migration

authors： Gregory CD,Rossi AG,Bournazou I,Zhuang L,Willems JJ

更新日期：2011-07-01 00:00:00

abstract：:Over 20 years ago, protrusive, F-actin-based membrane structures, termed invadopodia, were identified in highly metastatic cancer cell lines. Invadopodia penetrate artificial or explanted extracellular matrices in 2D culture conditions and have been hypothesized to facilitate the migration of cancer cells through base...

journal_title：Cell adhesion & migration

authors： Lohmer LL,Kelley LC,Hagedorn EJ,Sherwood DR

更新日期：2014-01-01 00:00:00